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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19823 results in Negative / Null Result Report · page 230 of 661

Negative / Null Result ReportMedicine

Comparison of visual performance among three higher-order aspheric enhanced monofocal intraocular lenses and a standard aspheric monofocal lens.

Hayashi S, Yoshida M, Hayashi K et al. · 2025 · Journal of cataract and refractive surgery

Purpose To compare visual performance among 3 types of higher-order aspheric enhanced monofocal intraocular lenses (IOLs) and a standard aspheric monofocal IOL. Setting Hayashi Eye Hospital, Fukuoka, Japan. Design Randomized comparative…

View details →DOI: 10.1097/j.jcrs.0000000000001734
Negative / Null Result ReportMedicine

Comparative outcomes of Mini-PCNL and suction-assisted flexible ureteroscopy in patients with renal stones ≥2 cm.

Durak HM, Sancı A, Hepşen E et al. · 2026 · Actas urologicas espanolas

Introduction To compare the efficacy and perioperative outcomes of miniaturized percutaneous nephrolithotomy (mini-PCNL) and flexible ureteroscopy with flexible and navigable suction ureteral access sheath (FANS-UAS) in the management of…

View details →DOI: 10.1016/j.acuroe.2026.501997
Negative / Null Result ReportMedicine

Sleep and emotional memory of preschool children adopted from foster care: a comparison with a community sample.

Rusin K, Myers A, Rech ME et al. · 2026 · Journal of pediatric psychology

Objective Children who spend time in foster care are at risk for adverse developmental outcomes, including sleep problems. Yet, research examining sleep and emotional memory has primarily focused on children with no history of foster care…

View details →DOI: 10.1093/jpepsy/jsag039
Negative / Null Result Report

Increasing clinical utility of prenatal exome sequencing: the potential power of phenotype-driven Artificial Intelligence analysis

Suerink M, Hoffer M, Dingemans A et al. · 2026 · Preprint

Abstract Prenatal exome sequencing (pES) is challenging due to rapid turnaround requirements and limited phenotype information. Analysis strategies span gene panels through exome-wide review, with Artificial Intelligence (AI) as optional…

View details →DOI: 10.21203/rs.3.rs-9634215/v1
Negative / Null Result ReportMedicine

Day-case versus conventional inpatient artificial urinary sphincter implantation: A single-center comparative study of 177 patients.

Youssef MW, Perrin L, Denormandie AC et al. · 2026 · The French journal of urology

Purpose Ambulatory artificial urinary sphincter (AUS) implantation has been proposed as an alternative to conventional inpatient surgery, but comparative data remain limited. We aimed to compare early postoperative outcomes between…

View details →DOI: 10.1016/j.fjurol.2026.103135
Negative / Null Result ReportMedicine

The benefit of robotic gastrectomy in minimally invasive surgery for elderly patients: a propensity score-matched analysis.

Jinushi K, Saito T, Fujikawa K et al. · 2026 · Surgery today

Purposes Robotic gastrectomy (RG) offers superior dexterity and visualization compared with laparoscopic gastrectomy (LG). However, its high cost requires careful patient selection. This study aimed to evaluate whether these advantages…

View details →DOI: 10.1007/s00595-026-03292-2
Negative / Null Result ReportMedicine

Antioxidant, Redox, and Immunomodulatory Effects of <i>Hypericum perforatum</i> in the <i>Galleria mellonella</i>: A 3R-Oriented Invertebrate Model.

Battal F, Kaya S, Kiraz HA · 2026 · Biomedicines

Background/Objectives : Hypericum perforatum L. (St. John's Wort) is extensively utilized in ethnopharmacology due to its anti-inflammatory and immunomodulatory properties. However, its effects on the interaction between innate immunity…

View details →DOI: 10.3390/biomedicines14061297
Negative / Null Result ReportMedicine

Evaluating junior medical staff confidence in assessment and management of mental health presentations in an Australian paediatric emergency department.

Daoud J, Greenwood J, Botha T et al. · 2026 · Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists

ObjectiveTo evaluate confidence levels of junior doctors working in the paediatric emergency department (ED) in the assessment and management of acute mental health presentations.MethodsThis cross-sectional study invited 89 eligible junior…

View details →DOI: 10.1177/10398562261424122
Negative / Null Result ReportMedicine

Artificial Intelligence Applications Versus Manual Methods For Literature Retrieval: A Comparative Analysis.

O'Rourke J, Byrne M, Schroers G · 2026 · Western journal of nursing research

Background Artificial intelligence (AI), particularly generative and large language models, is being used in nursing education, practice, and scholarly writing. Generative AI applications have been specifically examined for their use in…

View details →DOI: 10.1177/01939459261451723
Negative / Null Result ReportMedicine

Retrospective study on diagnostic yield and medical impact of diagnostic imaging in dogs with immune-mediated haemolytic anaemia in Belgium.

Vlassenbroek R, Peeters D, Matthewman L et al. · 2026 · The Journal of small animal practice

Objectives To assess the incidence of associative immune-mediated haemolytic anaemia in dogs diagnosed with immune-mediated haemolytic anaemia and to evaluate whether performing diagnostic imaging, specifically thoracic radiographs and…

View details →DOI: 10.1111/jsap.70159
Negative / Null Result ReportMedicine

Stabilizing Segmental Le Fort I Osteotomy Using Clear Thermoplastic Retainers Versus Arch Bars With Occlusal Splints: A Retrospective Analysis.

Wu L, Xu X, Liu X et al. · 2026 · The Journal of craniofacial surgery

In patients receiving segmental Le Fort I osteotomy as part of a clear aligner treatment regimen, this study aimed to compare the clinical effectiveness of clear thermoplastic retainers as a postoperative stabilization technique and…

View details →DOI: 10.1097/scs.0000000000012825
Negative / Null Result ReportMedicine

Midterm Clinical and Echocardiographic Outcomes After Transcatheter Aortic Valve Replacement in Patients With Severe Bicuspid Aortic Valve Stenosis.

Nienaber S, Krabichler K, Fahlbusch D et al. · 2026 · Journal of the American Heart Association

Background Outcomes >2 years after transcatheter aortic valve replacement (TAVR) for bicuspid aortic valves (BAV) are scarce, and differences between balloon-expandable transcatheter heart valves (THVs) and self-expandable (SE-THVs) are…

View details →DOI: 10.1161/jaha.125.047634
Negative / Null Result ReportMedicine

Three-Year Outcomes of Supera Interwoven Nitinol Stents Versus Eluvia Drug-Eluting Stents in Severely Calcified Femoropopliteal Lesions.

Yanagiuchi T, Tokuda T, Yoshioka N et al. · 2026 · Journal of vascular surgery

Objective To compare the 3-year outcomes of Supera interwoven nitinol stents (IWNS) and Eluvia fluoropolymer-based drug-eluting stents (DES) in patients with severely calcified femoropopliteal lesions. Methods This multicenter…

View details →DOI: 10.1016/j.jvs.2026.06.068
Negative / Null Result ReportMedicine

Comparative Outcomes of Exogenous and Endogenous MRSA Vs MSSA Endophthalmitis.

Katragadda KP, Palestine AG · 2026 · Ocular immunology and inflammation

Purpose Methicillin-resistant Staphylococcus aureus (MRSA) is associated with a worse systemic prognosis compared to methicillin-sensitive S. aureus (MSSA). Prior studies of MRSA and MSSA endophthalmitis group endogenous and exogenous…

View details →DOI: 10.1080/09273948.2026.2679851
Negative / Null Result ReportMedicine

Switching patterns of GLP-1 receptor agonists from 2018 to 2025 in the largest private healthcare network in Poland.

Łupina K, Dziewierz A, Janczura J et al. · 2026 · Acta diabetologica

Aims To characterize switching among GLP-1 receptor agonists (GLP-1 RAs) in a large private-sector cohort in Poland and to quantify therapy- and patient-level associations with switching while accounting for switching opportunity and…

View details →DOI: 10.1007/s00592-026-02709-1
Negative / Null Result ReportMedicine

The Clinical Impact of Team Triage vs Conventional Triage on Patients With Acute Surgical Appendicitis or Cholecystitis.

Adams JL, Tong A, Chen P et al. · 2026 · Journal of emergency nursing

Introduction Team triage incorporates collaborative evaluation by physicians and nurses during initial assessment, differing from conventional nurse-only triage models. Although previous studies have demonstrated improvements in wait times…

View details →DOI: 10.1016/j.jen.2026.04.016
Negative / Null Result ReportMedicine

Increased Retinol Levels in Patients with Cardiac Surgery-Associated Acute Kidney Injury-A Prospective Single-Center Exploratory Study.

Olasińska-Wiśniewska A, Swora-Cwynar E, Urbanowicz T et al. · 2026 · Nutrients

Background Acute kidney injury (AKI) is a frequent and prognostically important complication of cardiac surgery, yet early risk stratification remains challenging. The purpose of this prospective exploratory study was to determine whether…

View details →DOI: 10.3390/nu18121921
Negative / Null Result ReportMedicine

Comparative Analysis of Clinically Meaningful Recovery Trajectories Following Unicompartmental Arthroplasty and Patello-Femoral Arthroplasty.

Singh R, Williams DL, Alexander J et al. · 2026 · The Journal of arthroplasty

Background Medial unicompartmental knee arthroplasty (UKA), lateral UKA, and patello-femoral arthroplasty (PFA) are established treatments for isolated compartmental knee osteoarthritis. Despite its growing popularity, the comparative…

View details →DOI: 10.1016/j.arth.2026.06.020
Negative / Null Result ReportMedicine

No serological association between Porphyromonas gingivalis or Prevotella intermedia and early spondyloarthritis: analysis from the DESIR cohort.

Zekre F, Neel T, Paul M et al. · 2026 · Clinical and experimental medicine

Porphyromonas gingivalis and Prevotella intermedia are key oral pathogens implicated in periodontal disease and have been associated with rheumatoid arthritis and specific categories of juvenile idiopathic arthritis. Whether oral dysbiosis…

View details →DOI: 10.1007/s10238-026-02204-5