Negative / Null Result ReportMedicine
Benomar A, Fahed R, Omar AT et al. · 2026 · Journal of neurointerventional surgery
Background The Alberta Stroke Program Early CT Score (ASPECTS) and CT angiography (CTA) Collateral Score (CS) are routinely used to estimate ischemic core burden and collateral status in acute ischemic stroke due to large vessel occlusion,…
View details →DOI: 10.1136/jnis-2026-025321 Negative / Null Result ReportMedicine
Singhal M, Nidadavole K, Murphy DS et al. · 2026 · Journal of pharmaceutical sciences
Dissolution testing is performed to understand the rate and extent of drug release for assurance of in vivo bioavailability. In this case study, an immediate-release tablet of an investigational BCS Class II compound exhibited slow and…
View details →DOI: 10.1016/j.xphs.2026.104368 Negative / Null Result Report
Smith HJ, Delf B, Rosi V et al. · 2026 · Preprint
Artificial voices are encountered frequently in modern life, including artificial “clones” of an individual’s voice. For natural voices, familiar talkers are more intelligible than unfamiliar talkers when competing speech is present, which…
View details →DOI: 10.31234/osf.io/6bu8x_v1 Negative / Null Result ReportMedicine
Dolak KD, Davila S, White PC · 2026 · BMC pediatrics
Background Procalcitonin is a useful screen for bacterial infection, but its utility in pediatric diabetic ketoacidosis (DKA) is unknown. Methods We conducted a retrospective study of DKA patients admitted to two pediatric hospitals in…
View details →DOI: 10.1186/s12887-026-07114-9 Negative / Null Result Report
Kobas B, Koth SC, Reitmayer A et al. · 2026 · Preprint
Abstract Continuous mechanical cooling is commonly used to maintain thermal comfort in office environments; however, its influence on human thermophysiological adaptation under sedentary conditions remains poorly understood. This study…
View details →DOI: 10.21203/rs.3.rs-9747541/v1 Negative / Null Result ReportMedicine
Drake C, Buckman C, Brucker A et al. · 2026 · JAMA internal medicine
Importance Patients with diabetes and food insecurity are at greater risk of adverse health outcomes. Effective strategies to promote healthy food access are urgently needed. Objective To evaluate the effect of a produce prescription (PRx)…
View details →DOI: 10.1001/jamainternmed.2025.8008 Negative / Null Result ReportMedicine
Tamás S, György H, András M et al. · 2026 · The international journal of lower extremity wounds
IntroductionThe treatment of chronic non-healing wounds represents a great challenge in healthcare, especially in rehabilitation medicine, as it contributes significantly to increased patient mortality and morbidity. Various types of laser…
View details →DOI: 10.1177/15347346261461464 Negative / Null Result ReportMedicine
de Wasseige S, Mainguy-Seers S, Lavoie JP · 2026 · Equine veterinary journal
Background During clinical remission of severe equine asthma (SEA), affected animals can be challenging to distinguish from healthy horses. In humans, the degree of bronchodilation achieved with a β 2 -adrenergic bronchodilator is helpful…
View details →DOI: 10.1002/evj.70212 Negative / Null Result ReportMedicine
Untan I, Sabur V · 2026 · International journal of general medicine
Background Flank pain is a common emergency department (ED) presentation with a wide differential diagnosis. The albumin-to-globulin ratio (AGR) reflects both nutritional status and systemic inflammation, but its utility in…
View details →DOI: 10.2147/ijgm.s602023 Negative / Null Result ReportOpen accessMedicine
Lee-Miller CA, Kairalla JA, Hibbitts E et al. · 2026 · Blood advances
Abstract Patients with central nervous system (CNS) disease at diagnosis on Children's Oncology Group (COG) B-acute lymphoblastic leukemia (B-ALL) trials AALL0331 and AALL0232 had inferior outcomes, largely secondary to CNS relapse. In…
View details →DOI: 10.1182/bloodadvances.2026019660 Negative / Null Result ReportMedicine
Kong BH, Dillon K, Brady CM et al. · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
ObjectiveTo determine whether the Centers for Disease Control and Prevention's Social Vulnerability Index (SVI) influences models of adherence to speech evaluations beyond individual demographic and clinical factors.DesignRetrospective…
View details →DOI: 10.1177/10556656261436717 Negative / Null Result ReportMedicine
Matsuo A, Kanaya M · 2026 · Psychoneuroendocrinology
Stress contributes significantly to visceral pain hypersensitivity in irritable bowel syndrome (IBS). Although stress during critical developmental periods, such as chronic social defeat stress (CSDS) in adolescence or early-life…
View details →DOI: 10.1016/j.psyneuen.2026.107848 Negative / Null Result ReportMedicine
Wamsley EJ, Barron J, Livingston WH · 2026 · Journal of cognitive neuroscience
Memory is consolidated during "offline" states of reduced attention to the external stimulus environment, including sleep and resting wakefulness. While consolidation is usually studied on a timescale of hours to days, accumulating…
View details →DOI: 10.1162/jocn.a.2589 Negative / Null Result ReportMedicine
Piazza FRG, Schuch JB, Ferreira DNSDS et al. · 2025 · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Objective N-acetylcysteine (NAC) is a medication known for its hepatoprotective properties and potential to reduce cravings and psychoactive substance use. Vitamin D is metabolized in the liver, and individuals with alcohol abuse often…
View details →DOI: 10.47626/1516-4446-2025-4304 Negative / Null Result ReportMedicine
Chen PA, Hsueh YC, Lin YC et al. · 2026 · The Journal of arthroplasty
Background Whether the addition of magnesium sulfate (MgSO 4 ) to intra-articular analgesic cocktails improves early pain after total knee arthroplasty (TKA) remains uncertain. Methods This prospective, double-blind, within-patient…
View details →DOI: 10.1016/j.arth.2026.04.066 Negative / Null Result ReportMedicine
Leak M, Giambini H, Cheever K et al. · 2026 · Journal of sport rehabilitation
Context Thoracic mobility is integral to respiratory function and mobility of the neck, shoulder, and spine. The efficacy of thoracic mobility exercises in enhancing respiratory function and spinal range of motion (ROM) is well documented…
View details →DOI: 10.1123/jsr.2025-0061 Negative / Null Result ReportMedicine
Mayer J, Al-Sheikhli J, Wang X et al. · 2026 · JACC. Clinical electrophysiology
Background Functional extra-stimulus (ES) substrate mapping has been shown to reduce the recurrence of ventricular tachycardia (VT) compared with intrinsic rhythm mapping. However, there is no standardized approach to functional ES…
View details →DOI: 10.1016/j.jacep.2025.11.006 Negative / Null Result ReportMedicine
Mattila N, Meinberg M, Juppo A et al. · 2026 · Scandinavian journal of gastroenterology
Objective To assess whether a gargled articaine solution makes gastroscopy more tolerable for the patient. Background Gastroscopy is an unpleasant experience for most people. A drug that is easy to use, has a fast onset, enables quick…
View details →DOI: 10.1080/00365521.2026.2654974 Negative / Null Result ReportMedicine
Hoberstorfer T, Nopp S, Steiner D et al. · 2026 · Journal of thrombosis and haemostasis : JTH
Growth differentiation factor-15 (GDF-15) has been proposed as a bleeding biomarker. To evaluate the predictive value of GDF-15 for clinically relevant bleeding (CRB, major bleeding and clinically relevant non-major bleeding [CRNMB])…
View details →DOI: 10.1016/j.jtha.2026.06.023 Negative / Null Result ReportMedicine
Asmundo L, Pansini V, Monti CB et al. · 2026 · Abdominal radiology (New York)
To evaluate the diagnostic performance of hepatic extracellular volume (ECV) fraction derived from delayed single-energy CT for identifying graft rejection in liver transplant recipients and its added value over clinical parameters. This…
View details →DOI: 10.1007/s00261-026-05647-2 Negative / Null Result Report
Li M, Xie T, Liu H et al. · 2026 · Preprint
Abstract Theileria orientalis is a group of tick‑borne protozoan parasites responsible for significant economic losses in cattle worldwide. We previously reported an outbreak of oriental theileriosis due to mixed infection of T. orientalis…
View details →DOI: 10.21203/rs.3.rs-9797774/v1 Negative / Null Result Report
Dinç G, Öztürk B, Ciğerim SÇ · 2026 · Preprint
Abstract Objectives Sagittal skeletal classification is central to orthodontic diagnosis. This study aimed to (1) develop and validate an interpretable machine learning (ML) model for three-class sagittal skeletal classification (Class I,…
View details →DOI: 10.21203/rs.3.rs-9470812/v1 Negative / Null Result Report
Anderson JW, Shaikh N, Cooper GF et al. · 2026 · Preprint
Abstract Fairness is an important concern in statistical models, especially in clinical prediction models. Most fairness methods focus on model predictions, aiming for parity in model performance across relevant groups. However, this…
View details →DOI: 10.21203/rs.3.rs-9644545/v1 Negative / Null Result Report
Olgun A, Zengin S · 2026 · Preprint
Abstract Purpose. To evaluate whether prompt structure changes large language model-recommended triage in urologic patient messages and whether safety-focused prompting reduces unsafe undertriage without increasing overtriage. Methods. In…
View details →DOI: 10.21203/rs.3.rs-9453460/v1 Negative / Null Result Report
Schwartz MA, Lue D, Mutaher M et al. · 2026 · Preprint
Stem-like TCF7+ CD8 T cells sustain anti-tumor responses and support immune checkpoint blockade. We systematically identified regulators of this cell state using genome-wide CRISPR screens in primary T cells in vitro . Using random…
View details →DOI: 10.64898/2026.06.14.732162 Negative / Null Result ReportMedicine
Kikkawa K, Takeuchi M, Sakaguchi D et al. · 2026 · Journal of anesthesia
Purpose Monitored anesthesia care (MAC) is increasingly used for various procedures, but sedation-related upper airway obstruction may lead to hypoxemia or conversion to general anesthesia. This study evaluated whether preoperative tongue…
View details →DOI: 10.1007/s00540-026-03792-y Negative / Null Result ReportMedicine
Jin Z, Ueda K, Higo F et al. · 2026 · Anesthesia and analgesia
Background Prehabilitation during unavoidable surgical delay after an acute femoral neck fracture may mitigate rapid functional decline but is often limited by movement-evoked pain. The pericapsular nerve group (PENG) block is a…
View details →DOI: 10.1213/ane.0000000000008147 Negative / Null Result ReportMedicine
Navarro LP, Combes X, Galinski M et al. · 2026 · BMC emergency medicine
Introduction We aimed to assess the relationship between arterial partial pressure of carbon dioxide (PaCO 2 ) and end-tidal carbon dioxide (EtCO 2 ) according to three prehospital hemodynamic status and to evaluate whether…
View details →DOI: 10.1186/s12873-026-01649-x Negative / Null Result ReportMedicine
Jorritsma R, Bijkerk HJC, Martina R et al. · 2026 · Irish veterinary journal
In September 2023, the official national reference laboratory confirmed the presence of BTV serotype 3 in The Netherlands. In the following weeks, it appeared that the infection caused very severe clinical signs in sheep, but it was…
View details →DOI: 10.1186/s13620-026-00351-5 Negative / Null Result ReportMedicine
Burtnett SL, Bomberger RA, Harvatine KJ · 2026 · Journal of dairy science
Oleic acid has a lower risk for biohydrogenation-induced milk fat depression (MFD) than linoleic acid and can act as an emulsifier to aid fatty acid (FA) digestion in the small intestine. Our objective was to evaluate the effect of high…
View details →DOI: 10.3168/jds.2026-28283 