Negative / Null Result ReportMedicine
Gabrielsen R, Tellum T, Bø K et al. · 2025 · Journal of physiotherapy
Question How much does adding supervised group and independent individual exercise including pelvic floor muscle training (PFMT) to multidisciplinary pain management affect pelvic and genital pain in women with endometriosis? How much does…
View details →DOI: 10.1016/j.jphys.2025.09.012 Negative / Null Result ReportMedicine
Redman N, Brumbaugh K, Farquharson K · 2025 · Seminars in speech and language
This investigation compared the effectiveness of the Cycles Approach with and without auditory stimulation. Using an alternating treatment design (AATD), three preschool-aged children with severe phonological disorders received a modified…
View details →DOI: 10.1055/a-2719-4944 Negative / Null Result Report
Li X, Yan M, Li T et al. · 2025 · Preprint
Abstract Background Perineural invasion (PNI), though reported with varying incidence in rectal cancer, is a recognized marker of adverse prognosis. While postoperative adjuvant radiotherapy is a cornerstone of multidisciplinary management…
View details →DOI: 10.21203/rs.3.rs-8387361/v1 Negative / Null Result ReportMedicine
Minkley M, Ravasia K, Nghiem T et al. · 2026 · Virchows Archiv : an international journal of pathology
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is an aggressive and molecularly heterogenous cancer with poorly defined treatment strategies. We aimed to (i) assess whether RB1 immunohistochemistry alone can prognostically stratify…
View details →DOI: 10.1007/s00428-026-04440-2 Negative / Null Result ReportMedicine
Kakihara S, Busza AM, Duffy BV et al. · 2026 · American journal of ophthalmology
Objective To determine whether foveal avascular zone (FAZ) enlargement and geometric perfusion deficits in the deep capillary plexus (GPDd) are independently associated with retinal nonperfusion in different regions of ultrawidefield…
View details →DOI: 10.1016/j.ajo.2026.03.031 Negative / Null Result Report
Bansaghi S, Klein J · 2026 · Preprint
Background Cruise ships are relatively small, crowded spaces where many people travel in a new environment, making infection control especially important. Proper hand hygiene is the first line of defense against the spread of infection.…
View details →DOI: 10.12688/openreseurope.20172.3 Negative / Null Result ReportMedicine
Kuula L, Pesonen AK · 2026 · The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Purpose Many adolescents develop very late circadian rhythms, indicating delayed sleep phase. Interventions are sparse, and the stability of any improvements is rarely reported. To evaluate how late sleep patterns can be improved, we…
View details →DOI: 10.1016/j.jadohealth.2025.12.247 Negative / Null Result ReportOpen accessMedicine
Silva LEV, Balcarcel D, Ko TS et al. · 2026 · Resuscitation
Aims Heart rate variability (HRV), a non-invasive measure of autonomic function, may offer prognostic value after pediatric cardiac arrest. We used machine learning models to determine whether HRV features within the first 24 h after…
View details →DOI: 10.1016/j.resuscitation.2026.110961 Negative / Null Result ReportMedicine
Miao Y, Zhang H, Wu J et al. · 2026 · Journal of clinical anesthesia
Background Clinical evidence on obturator nerve involvement after supra-inguinal fascia iliaca compartment block (SFICB) is limited. This study aimed to investigate whether a 40-mL SFICB reliably anesthetizes the obturator nerve and…
View details →DOI: 10.1016/j.jclinane.2026.112193 Negative / Null Result Report
Bori-Bru B, Salvador JP, Crehuet R · 2025 · Preprint
Generative models have advanced profusely in recent years, generating great impact in computational modelling and structural bioinformatics. A part of computational protein design focuses on antibody and nanobody engineering, targeting…
View details →DOI: 10.64898/2025.12.12.693880 Negative / Null Result ReportMedicine
Najjar-Debbiny R, Cohen R, Arbel A et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
BACKGROUND: Mycobacterium simiae is an emerging cause of non-tuberculous mycobacterial pulmonary disease (NTM-PD) in the Middle East, yet treatment outcomes remain unclear. We aimed to evaluate clinical and microbiologic outcomes of M.…
View details →DOI: 10.1007/s10096-026-05468-7 Negative / Null Result ReportMedicine
Rhyu KH, Cho YJ, Chun YS et al. · 2026 · Clinical orthopaedics and related research
Background Cementing a new liner into a well-fixed acetabular cup with a deficient locking mechanism has been reported as a viable option, but concerns remain regarding complications such as dislocation and late loosening.…
View details →DOI: 10.1097/corr.0000000000003917 Negative / Null Result Report
Morales AA, Camarena V, Peart L et al. · 2025 · Preprint
Abstract Geleophysic dysplasia (GD) is a rare genetic disorder characterized by short stature, joint contractures, and cardiopulmonary complications, with early mortality, and linked to mutations in ADAMTSL2 (GD1), FBN1 (GD2), or LTBP3…
View details →DOI: 10.21203/rs.3.rs-8301608/v1 Negative / Null Result ReportMedicine
Fatima H, Schaffert J, Carlew AR et al. · 2025 · The Clinical neuropsychologist
Objective Cognitive dispersion (CD) or neuropsychological test score variability has been associated with more rapid cognitive decline, and the development of mild cognitive impairment (MCI) and Alzheimer's disease (AD). The predictive…
View details →DOI: 10.1080/13854046.2025.2577149 Negative / Null Result ReportMedicine
Agyeman AA, Buggiotti L, Brown LK et al. · 2026 · British journal of clinical pharmacology
Aims The repurposed use of favipiravir in COVID-19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it…
View details →DOI: 10.1002/bcp.70507 Negative / Null Result ReportMedicine
Khoshnevis A, Zayernouri M, Malete L et al. · 2026 · Journal of voice : official journal of the Voice Foundation
Objective Voice-based biomarkers have been proposed as objective tools for anxiety assessment, yet existing research relies on small, demographically homogeneous samples and shows inconsistent associations between fundamental frequency (F…
View details →DOI: 10.1016/j.jvoice.2026.03.014 Negative / Null Result ReportMedicine
Kwon Y, Park J, Kim D et al. · 2026 · Obesity surgery
Background While bariatric surgery (BS) is an effective treatment for gout in patients with morbid obesity, little is known about how BS influences subsequent use of gout medications. We investigated the impact of BS on gout medication…
View details →DOI: 10.1007/s11695-025-08445-9 Negative / Null Result ReportMedicine
Golparian A, Anbarian M, Golparian M · 2026 · Journal of biomechanics
Anterior cruciate ligament deficiency (ACLD) leads to knee instability and altered gait patterns. Individuals with ACLD can be classified as copers or noncopers. Lower-limb coordination and coordination variability may reflect compensatory…
View details →DOI: 10.1016/j.jbiomech.2026.113416 Negative / Null Result ReportMedicine
Sınır B, Ortan P, Sayin SS et al. · 2026 · Respiratory medicine
Purpose Obstructive sleep apnea syndrome (OSAS) causes intermittent hypoxia and sleep fragmentation, which may alter gut microbiota composition. We primarily aimed to compare intestinal Desulfovibrio detection/abundance between patients…
View details →DOI: 10.1016/j.rmed.2026.108986 Negative / Null Result Report
Kumar A, Sinha RRK, Sahu SP et al. · 2026 · Preprint
Abstract The present experiment was conducted to compare three housing systems Individual cages, Colony cages and Deep litter on welfare, behaviour, and physiological traits in Rhode Island Red laying hens under tropical conditions. A…
View details →DOI: 10.21203/rs.3.rs-9950223/v1 Negative / Null Result ReportMedicine
Okumura M, Yamagami S, Akiyama M et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
Introduction Pulsed field ablation (PFA) is a non-thermal ablation modality, but repeated high-voltage applications can still cause Joule heating at the electrode-tissue interface. We evaluated the effects of application repetition and…
View details →DOI: 10.1007/s10840-026-02379-7 Negative / Null Result ReportMedicine
Xiang F, Lin J, Chen B et al. · 2026 · The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
Background To compare the superthin (3-5 mm) versus conventional (≥10 mm) anterolateral thigh (ALT) flap for post-traumatic ankle reconstruction. Methods Retrospective cohort (2020-2024): superthin ALT (n=26) vs conventional ALT (n=34).…
View details →DOI: 10.1053/j.jfas.2026.06.019 Negative / Null Result ReportMedicine
Sabharwal P, Kaur N, Kaur R et al. · 2026 · Journal of ultrasound
Objectives To determine the incremental diagnostic value of multiparametric quantitative ultrasound-integrating B-mode, Color Doppler, Strain, and Shear Wave Elastography (SWE)-in differentiating benign and malignant breast lesions, using…
View details →DOI: 10.1007/s40477-026-01116-0 Negative / Null Result ReportMedicine
Wang L, Pulgrossi RC, Anderson J et al. · 2026 · The journal of applied laboratory medicine
Background Acute graft-versus-host disease (aGVHD) is a common complication of allogenic hematopoietic cell transplantation (HCT). The aGVHD presymptomatic algorithm is comprised of 2 serum biomarkers, suppression of tumorigenicity 2 and…
View details →DOI: 10.1093/jalm/jfaf193 Negative / Null Result ReportMedicine
Delaye-Martínez MA, Aguilar-Rodea BP, Cardona-Ortiz AF et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Purpose Nebulized colistin has shown promise in treating ventilator-associated pneumonia (VAP) due to carbapenem-resistant strains; evidence in burn patients is limited. This study evaluated the efficacy of nebulized colistin as an adjunct…
View details →DOI: 10.1007/s10096-026-05550-0 Negative / Null Result ReportMedicine
Rusa AM, Schmidlin PR, Sarkar P et al. · 2026 · Swiss dental journal
Large language models (LLMs) are increasingly used in clinical and educational settings. However, there is a paucity of data on LLMs' performance in specialized dental domains. This study assessed the performance of four LLMs, including…
View details →DOI: 10.61872/sdj-2025-04-04 Negative / Null Result ReportMedicine
Zou Q, Huang Q, Li J et al. · 2026 · International urology and nephrology
Background The optimal treatment strategy for androgen receptor pathway inhibitor (ARPI)-pretreated and chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) remains unclear. Chemotherapy has limited efficacy as a…
View details →DOI: 10.1007/s11255-026-05064-w Negative / Null Result Report
Oscorbin IP, Smertina MA, Kunova MS et al. · 2025 · Preprint
The metal-binding periplasmic protein CusF has been proposed as a bifunctional tag enhancing solubility of recombinant proteins and enabling purification using Cu affinity chromatography. However, evidence for its performance remains…
View details →DOI: 10.20944/preprints202512.0908.v1 Negative / Null Result ReportMedicine
van Boven M, Bennis F, Onland W et al. · 2025 · IEEE journal of biomedical and health informatics
Machine learning models predicting neurodevelopmental outcome in preterm infants have great potential, but have often relied on inaccessible brain magnetic resonance imaging measurements. This study aimed to build models using readily…
View details →DOI: 10.1109/jbhi.2025.3559793 Negative / Null Result ReportMedicine
Hoyle JD Jr, Ekblad G, Dunwoody S et al. · 2026 · Prehospital emergency care
Objectives We sought to decrease pediatric prehospital dosing errors by implementing a bundled drug dosing safety system (DDSS). Multiple studies have demonstrated that pediatric prehospital drug-dosing errors occur at rates of > 30% for…
View details →DOI: 10.1080/10903127.2025.2609784 