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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21697 results · page 208 of 724

Negative / Null Result ReportMedicine

A Geospatially Customizable Culturally Tailored Just-in-Time Adaptive Intervention for Violence-Affected People Living With HIV: Mixed Methods Acceptability, Feasibility, and User Experience Study.

Skeen, Tokarz, Gasik et al. · 2026 · JMIR human factors

Posttraumatic stress, along with comorbid mental health challenges and hazardous alcohol use, disproportionately affects people living with HIV. The drivers of these stressors are both intraindividual, rooted in early life adversity and…

View details →DOI: 10.2196/80705
Negative / Null Result ReportMedicine

When performance declines: culturally mediated delay in pediatric knee fracture following traditional healing and scarification-a case report from rural Cameroon.

Npochinto Moumeni, Dikongue · 2026 · Frontiers in pediatrics

Delayed presentation of pediatric musculoskeletal trauma remains a critical yet underexplored challenge in sub-Saharan Africa, where cultural beliefs, socioeconomic constraints, and reliance on traditional healing practices frequently…

View details →DOI: 10.3389/fped.2026.1810974
Negative / Null Result ReportMedicine

Effect of Vaginal Palpation on Voluntary Pelvic Floor Muscle Performance During Early Motor Learning in Women with Stress Urinary Incontinence (SUI): A Randomized Controlled Trial.

de Azevedo Ferreira, Fitz, Gimenez et al. · 2026 · International urogynecology journal

Seventy percent of women with pelvic floor muscle (PFM) dysfunction are unable to contract these muscles correctly. Instruction to contract properly is essential for effective PFM training (PFMT). The study aimed to compare two…

View details →DOI: 10.1007/s00192-026-06775-5
Negative / Null Result ReportMedicine

Nonlinear Association of Serum Sodium with Urine Output in Postoperative Pediatric Cardiac Patients Receiving Furosemide: A Retrospective Study.

Gilad, Jacover, Levy et al. · 2026 · Pediatric cardiology

Furosemide resistance and fluid overload remain major challenges in postoperative pediatric cardiac patients. Although adult studies suggest synergistic effects of hypertonic saline with loop diuretics, pediatric postoperative physiology…

View details →DOI: 10.1007/s00246-026-04341-w
Negative / Null Result ReportMedicine

Chronic Neutropenia in Children: A Single-Center Experience.

Roganović, Zubović, Đorđević et al. · 2026 · Acta medica academica

To analyze the characteristics, etiology, diagnostic evaluation, management, follow-up, and outcomes of children with chronic neutropenia treated at a tertiary care pediatric hospital in Croatia. We retrospectively reviewed the…

View details →DOI: 10.5644/ama2006-124.510
Negative / Null Result ReportMedicine

EXPRESS: Longitudinal evaluation of discordant symmetric dimethylarginine and creatinine as markers of glomerular filtration rate in radioiodine-treated hyperthyroid cats.

Hardy, Hibbert, Tasker et al. · 2026 · Journal of feline medicine and surgery

To determine the frequency and clinical significance of discordant serum symmetric dimethylarginine (SDMA) and creatinine concentrations relative to glomerular filtration rate (GFR) in mature and senior hyperthyroid cats treated with…

View details →DOI: 10.1177/1098612x261466163
Negative / Null Result ReportMedicine

AMCP Market Insights: Managed care considerations in Barth syndrome.

Flavin, Vernon, Todd Cade et al. · 2026 · Journal of managed care & specialty pharmacy

Barth syndrome is an ultrarare, complex, multisystem, X-linked metabolic and neuromuscular disease, which poses significant and wide-ranging burden to patients and caregivers. Pharmacologic management focuses on treatment of disease…

View details →DOI: 10.18553/jmcp.2026.32.7-b.s1
Negative / Null Result ReportMedicine

Effectiveness of intravenous infusion protocol in improving quality of care and reducing complications among hospitalized patients.

Ani, Hameed · 2026 · Wiadomosci lekarskie (Warsaw, Poland : 1960)

Aim: This study aimed to evaluate the effectiveness of a structured intravenous infusion protocol in improving the quality of care and reducing IV-related complications among hospitalized patients. Materials and Methods: A purposive sample…

View details →DOI: 10.36740/wlek/219896
Negative / Null Result ReportMedicine

Long-term mortality trends and disparities in renal failure across the United States, 1999 to 2024: A nationwide population-based ecological time-trend study.

Wang, Leng · 2026 · The Journal of international medical research

ObjectiveAlthough renal failure is an important cause of death in the United States, recent mortality trends and subgroup differences remain insufficiently characterized. This nationwide ecological time-trend study examined renal failure…

View details →DOI: 10.1177/03000605261463635
Negative / Null Result ReportMedicine

Fibrocartilaginous Embolism Presenting as Isolated L2-3 Radiculopathy without Spinal Cord Infarction.

Kim, Park, Park et al. · 2026 · American journal of physical medicine & rehabilitation

Lumbosacral radiculopathy often presents as back pain and lower limb weakness and is frequently encountered in rehabilitation medicine. Fibrocartilaginous embolism (FCE) is an uncommon but significant vascular cause of radiculopathy. It…

View details →DOI: 10.1097/phm.0000000000003002
Negative / Null Result ReportMedicine

The sound of engagement: assessing the feasibility and acceptability of an AI-generated personalized podcast as a between-session resource for therapy.

Peake, Swirbul, Rodio et al. · 2026 · Frontiers in digital health

Consistent client engagement with between-therapy session activities (i.e., homework) is a strong predictor of positive psychotherapy outcomes. Because traditional homework activities aren't always tailored to the individual, they can fail…

View details →DOI: 10.3389/fdgth.2026.1821642
Abandoned HypothesisMedicine

Early-Onset Amiodarone Pulmonary Toxicity at a Standard Maintenance Dose Masquerading as Decompensated Heart Failure: A Case Report and Literature Review.

Chabalout, Chaudhry, Inanc et al. · 2026 · Cureus

Amiodarone is a widely used antiarrhythmic agent. Pulmonary toxicity is its most feared non-cardiac complication and is classically associated with high doses and prolonged duration of therapy. We report a case of early-onset amiodarone…

View details →DOI: 10.7759/cureus.109617
Negative / Null Result ReportMedicine

Evaluation of electroacupuncture acupoint selection's potential in the treatment of inflammatory bowel disease: an investigation using a mouse gut microbiome and metabolomics model.

Lu, Bi, Gao et al. · 2026 · Frontiers in cellular and infection microbiology

Electroacupuncture (EA) serves as an effective complementary therapy in the treatment of inflammatory bowel disease (IBD) within traditional Chinese medicine, with the therapeutic efficacy significantly influenced by the selection of…

View details →DOI: 10.3389/fcimb.2026.1830455
Negative / Null Result ReportMedicine

Optimising the implementation of adolescent-friendly health services and its effects on contraceptive uptake and adolescent pregnancy in rural Mozambique: an implementation research study of the S-NICE intervention.

Chilundo, Xinavane, Huo et al. · 2026 · Frontiers in reproductive health

Despite national policies promoting adolescent- and youth-friendly health services, implementation gaps hinder improvements in adolescent sexual and reproductive health outcomes in Mozambique. S-NICE is a structured, participatory…

View details →DOI: 10.3389/frph.2026.1828528
Negative / Null Result ReportMedicine

The thyroid-heart axis-hormone dynamics and outcomes in cardiogenic shock following myocardial infarction.

Boettger, Sedighi, Pallmann et al. · 2026 · Journal of the Intensive Care Society

Thyroid hormone alterations are common in critical illness and may reflect disease severity. Their prognostic significance in infarct-related cardiogenic shock remains incompletely defined. In this prospective cohort study from a…

View details →DOI: 10.1177/17511437261454174
Negative / Null Result ReportMedicine

Persuasive Gamified Virtual Reality Experience to Enhance Engagement and Focus in Young Adults With Mild Anxiety Symptoms: Randomized Pilot Experimental Study.

Argaw, Jingili, Oyelere et al. · 2026 · JMIR XR and spatial computing

Anxiety-related symptoms are prevalent and can negatively affect concentration, motivation, and overall well-being. Traditional treatments such as cognitive behavioral therapy and medication work well for clinical anxiety disorders.…

View details →DOI: 10.2196/66713
Negative / Null Result ReportMedicine

Association of advanced therapies for intermediate- to high-risk pulmonary embolism with improved right ventricular function on outpatient follow-up among survivors.

Sheikh, Singh, Smith et al. · 2026 · Frontiers in cardiovascular medicine

The impact of catheter-directed thrombolysis (CDT), catheter-directed embolectomy (CDE) and surgical pulmonary embolectomy (SPE) on long term RV function among patients with acute PE remains unclear. We investigated the association of…

View details →DOI: 10.3389/fcvm.2026.1767184
Negative / Null Result ReportMedicine

Nutritional indicators and fluid self-efficacy among hemodialysis patients in the Qassim region, Saudi Arabia: a multicenter descriptive cross-sectional study.

Elmansy, Elbqry, Qalawa et al. · 2026 · Frontiers in nutrition

Hemodialysis is a life-sustaining renal replacement therapy that removes metabolic waste products normally eliminated by the kidneys. Patients undergoing hemodialysis are required to adhere to strict fluid and dietary restrictions to…

View details →DOI: 10.3389/fnut.2026.1820274
Negative / Null Result ReportMedicine

Dietary inclusion of black cumin ( Nigella sativa L.) seed meal in broiler chickens: Effects on growth performance, cecal microbiota, and cost efficiency.

Tilahun, Urge, Girma et al. · 2026 · Veterinary and animal science

The current study evaluated the effects of black cumin seed meal (BCSM) on growth performance, cecal microbiota, production efficiency, and cost efficiency in broiler chickens. A total of 144 one-day-old unsexed Cobb 500 broiler chicks…

View details →DOI: 10.1016/j.vas.2026.100731
Negative / Null Result ReportMedicine

Pre-synchronization with GnRH or hCG enhances fertility outcomes of heat synch protocol in Holstein dairy cows across parities: A pilot study.

Navidifar, Kaveh, Hosseini et al. · 2026 · Veterinary and animal science

Efficient estrus synchronization is important for improving reproductive performance in dairy herds; however, variations in ovarian activity among cows of different parities may influence responses to synchronization protocols. The present…

View details →DOI: 10.1016/j.vas.2026.100739
Negative / Null Result ReportMedicine

Effect of Chitosan Modification and Support Type on the Catalytic Properties of Supported Palladium Catalysts in Hydrogenation of 2-Propen-1-ol.

Naizabayev, Talgatov, Auyezkhanova et al. · 2026 · Molecules (Basel, Switzerland)

Palladium catalysts modified with chitosan (CS) and supported on MgO, SiO 2 , TiO 2 , and Al 2 O 3 were prepared by a precipitation method and evaluated in the low-temperature hydrogenation of 2-propen-1-ol. Chitosan was first deposited…

View details →DOI: 10.3390/molecules31122028