Failed Experiment ReportMedicine
Araujo, Araujo, Silva et al. · 2026 · Journal of motor behavior
The study investigated the effects of ten 20-minute sessions of neurofunctional motor training combined with anodal transcranial direct current stimulation (tDCS) over the primary motor cortex or cerebellum on motor skills in autistic…
View details →DOI: 10.1080/00222895.2026.2668719 Negative / Null Result ReportMedicine
Elenjickal, Baroz, Boileau et al. · 2026 · Diabetes, obesity & metabolism
Pharmacokinetic data suggest a potential dose-dependent effect of sodium-glucose co-transporter-2 (SGLT-2) inhibitors on surrogate markers of efficacy, but the impact of SGLT-2 inhibitor dose on renal and cardiovascular outcomes remains…
View details →DOI: 10.1111/dom.70886 Failed Experiment ReportMedicine
Idris, Burhan, Hajeer et al. · 2026 · The Journal of international medical research
ObjectiveTo investigate the effect of repeated submucosal administration of injectable platelet-rich fibrin in the buccal region of the lower incisors on orthodontically induced apical root resorption in patients with moderate…
View details →DOI: 10.1177/03000605261452234 Negative / Null Result ReportMedicine
Wilcox, Campbell, Gill et al. · 2026 · The bone & joint journal
Computer navigation is capable of improving the accuracy of glenoid baseplate and screw positioning in shoulder arthroplasty, but there is very limited evidence of its effect on clinical outcomes. In Australia, there is one commonly used…
View details →DOI: 10.1302/0301-620x.108b6.bjj-2025-1772.r1 Negative / Null Result ReportMedicine
Metter, Dumoulin, Hay et al. · 2026 · Scandinavian journal of gastroenterology
Endoscopic submucosal resection (ESR) is a novel resection technique. ESR is performed with a partially insulated snare, which allows a resection close to the proper muscle layer thus resecting in the deep submucosa. This should have…
View details →DOI: 10.1080/00365521.2026.2678594 Negative / Null Result ReportMedicine
García Alcaide, Conde Villar, Pérez Alfayate et al. · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe
To assess the impact of a tailored ergonomic lecture on postural risk among second-year endodontic residents depending on the use of no magnification, ergonomic loupes, or an operating microscope. A within-subjects, repeated measures…
View details →DOI: 10.1111/eje.70203 Negative / Null Result ReportMedicine
Qiao, Wang, Liu et al. · 2026 · BMC surgery
To evaluate the impact of sodium carboxymethyl cellulose (SCMC)-based absorbable hemostatic gauze on postoperative infectious outcomes in emergency laparoscopic appendectomy (LA) for acute appendicitis. A retrospective analysis of 184…
View details →DOI: 10.1186/s12893-026-03886-0 Negative / Null Result ReportMedicine
Herzog, Brink, Gondalia et al. · 2026 · Sports medicine (Auckland, N.Z.)
One often-stated aim of load management in elite athletes is injury reduction. However, current literature on the efficacy and effectiveness of specific load management strategies to reduce injury risk is limited. The aim of this study was…
View details →DOI: 10.1007/s40279-026-02457-w Negative / Null Result ReportMedicine
Wang, Liu, Wang et al. · 2026 · Journal of neuro-oncology
H3K27M-mutant diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brainstem tumor with a median overall survival (OS) of less than one year. Radiotherapy (RT) is the standard treatment, but the survival benefit of adding…
View details →DOI: 10.1007/s11060-026-05622-3 Negative / Null Result ReportMedicine
Prasert, Praphasiri, Ditsungnoen et al. · 2026 · The Journal of infectious diseases
Antigenically drifted influenza A(H3N2) subclade K viruses have contributed substantially to influenza burden since 2025, but their clinical severity is less well described. Using sentinel surveillance data from Thailand, we found no…
View details →DOI: 10.1093/infdis/jiag283 Negative / Null Result ReportMedicine
Keskin, Erdoğan, Küçükçetin et al. · 2026 · Psychiatry research
The aim of this study was to compare serum levels of Fibroblast Growth Factor-2 (FGF-2) and Fibroblast Growth Factor-9 (FGF-9) between patients with Bipolar Disorder (BD) and healthy controls (HC), and to evaluate whether these molecules…
View details →DOI: 10.1016/j.psychres.2026.117248 Negative / Null Result ReportMedicine
Li, Zhu, Xu et al. · 2026 · Advances in therapy
This study evaluated the efficacy and safety of cipepofol vs. dexmedetomidine for long-term sedation of patients undergoing mechanical ventilation (MV) in an intensive care unit (ICU). Adult patients who required invasive MV for…
View details →DOI: 10.1007/s12325-026-03640-1 Negative / Null Result ReportMedicine
Tan, Feng, Wen et al. · 2026 · Medicine
To investigate the effect of expressive writing intervention on optimism and coping modes of newly diagnosed people with human immunodeficiency virus (HIV). A total of 84 newly diagnosed people with HIV in the care clinic of Public Health…
View details →DOI: 10.1097/md.0000000000048936 Negative / Null Result ReportMedicine
Tao, Pan, Li et al. · 2026 · BMC emergency medicine
The impact of Emergency Medical Service (EMS) on the prognosis of patients with acute ischemic stroke (AIS) remains controversial. This prospective cohort study enrolled AIS patients admitted to the emergency department of the Central…
View details →DOI: 10.1186/s12873-026-01621-9 Negative / Null Result ReportMedicine
Sood, Turnbull, De Silva et al. · 2026 · Heart, lung & circulation
Improved patient outcomes after ventricular arrhythmia (VA) ablation procedure have been found to correlate with procedures being performed in high volume centres. Whether the concentration of expertise in experienced, urban centres…
View details →DOI: 10.1016/j.hlc.2025.12.026 Negative / Null Result ReportMedicine
Cheng, Zhu, Xie et al. · 2026 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
This study aimed to explore the association between different stroke onset types [unwitnessed stroke (UWS) vs. witnessed stroke (WS)] and clinical outcomes in patients with large ischemic stroke treated with endovascular therapy (EVT).…
View details →DOI: 10.1016/j.jocn.2026.112116 Negative / Null Result ReportMedicine
Sinsareekul, Chantarangsu, Hiran-Us · 2026 · Journal of dentistry
This retrospective study aimed to evaluate the influence of sealer extrusion on treatment outcomes using a within-tooth comparative design and to identify associated prognostic factors. A total of 126 patients who underwent nonsurgical…
View details →DOI: 10.1016/j.jdent.2026.106801 Negative / Null Result ReportMedicine
Susma, Spronken, van Nieuwkoop et al. · 2026 · Journal of virology
Cytosine-phosphate-guanine (CpG) dinucleotide motifs are the most underrepresented motifs in RNA virus genomes, including those of the influenza A viruses (IAV). Previous studies have indicated that increasing the number of CpG motifs in…
View details →DOI: 10.1128/jvi.00047-26 Negative / Null Result ReportMedicine
Adeoye, Ani, Egbokhare et al. · 2026 · Psychology, health & medicine
Sickle Cell Disorder (SCD) is a complex, multi-system blood condition affecting 7.78 million people, with 80% of global cases in sub-Saharan Africa, especially Nigeria. The condition is associated with physical health complications and…
View details →DOI: 10.1080/13548506.2026.2694730 Negative / Null Result ReportMedicine
Kaewmanee, Ganesan, Choochana et al. · 2026 · PloS one
Phy-Blica-O (PBO) is a traditional Thai polyherbal formulation historically regarded as a brain tonic and memory enhancer. Despite its long-standing ethnomedicinal use, its neuroprotective mechanisms have not been scientifically validated.…
View details →DOI: 10.1371/journal.pone.0352429 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Shingo Hatakeyama, Hayato Yamamoto, Akiko Okamoto et al. · 2012 · International Journal of Nephrology
The oral adsorbent AST-120 has the potential to delay dialysis initiation and improve survival of patients on dialysis. We evaluated the effect of AST-120 on dialysis initiation and its potential to improve survival in patients with chronic kidney disease. The present retrospective pair-matched study included 560 patients, grouped according to whether or not they received AST-120 before dialysis (AST-120 and non-AST-120 groups). The cumulative dialysis initiation free rate and survival rate were compared by the Kaplan-Meier method. Multivariate analysis was used to determine the impact of AST-
View details →DOI: 10.1155/2012/376128 Negative / Null Result ReportOpen accessScience (General)
Fan Liu, Peng Guo, Quan Wang et al. · 2023 · Heliyon
Background: Bowel volume loss during anus-preserving surgery (APS) may result in low anterior resection syndrome (LARS). We conducted this prospective observational cohort study to measure the incidence of LARS after surgery and evaluate the relationship between bowel volume loss and bowel function. Methods: Patients with R0 resectable rectal cancer who consented to several bowel function surveys through telephone interviews after the operation were included. Enrolled patients underwent standard APS for rectal cancer, and three length indexes, viz. length of excised bowel, length of the distal
View details →DOI: 10.1016/j.heliyon.2023.e17630 Negative / Null Result ReportOpen accessMedicine
Saumya Srivastava, Charu Eapen, Harramb Mittal · 2018 · Journal of Clinical and Diagnostic Research
Introduction: Shoulder Impingement Syndrome (SIS) is one of the common cause of shoulder ailment which leads to pain and restriction of the movements. Though Mobilisation with Movement and cryotherapy, both are found to be effective in managing SIS, there is no comparison done between the two treatments. Aim: To compare the effectiveness of Mobilisation With Movement (MWM) and cryotherapy in SIS. Materials and Methods: A randomised clinical trial was conducted on 22 subjects who aged between 18-64 years, and those who had a positive painful arc, three positive tests out of five i.e., Neer’s Im
View details →DOI: 10.7860/jcdr/2018/34624.12091 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Cleusa Ema Quilici Belczak, José Maria Pereira de Godoy, Amélia Cristina Seidel et al. · 2018 · International Journal of Vascular Medicine
Background. Elastic compression stockings (ECS) are effective in preventing and reducing occupational edema (OE), but the optimal pressure according to the prevalent working position during the day is still controversial. Objective. To compare the effectiveness of ECS with different pressures (15–20 mmHg or 20–30 mmHg) for reducing OE in individuals working in different prolonged postures. Methods. This cross-sectional study comprised 116 lower limbs of 58 individuals divided into three groups according to their prevalent postures over the day (sitting, standing, or combination). Volumetric me
View details →DOI: 10.1155/2018/2053985 Negative / Null Result ReportOpen accessPublic aspects of medicine
Juliana Cavalcanti Correia, Rosângela Maria Rodrigues Barbosa, Cláudia Maria Fontes de Oliveira et al. · 2012 · Revista de Saúde Pública
OBJECTIVE: Analyse how basic sanitation conditions, water supply and housing conditions affect the concentration of Culex quinquefasciatus METHODS: Populations of C. quinquefasciatus in 61 houses in the municipality of Olinda, PE, were monitored between October 2009 and October 2010. Observations were carried out in homes without the presence of preferred breeding sites in order to identify characteristics that may be aggravating factors for the development of the mosquito. Five aggravating factors were analysed: vegetation cover surrounding the home, number of residents/home, water storage, s
View details →DOI: 10.1590/s0034-89102013005000010 Negative / Null Result Report
Rose R. Andrade · 2025 · International journal of humanities and social sciences
This study was conducted to determine the level of perceptions, interests, and understanding of Florante at Laura among Grade 8 students of Ernesto R. Sicad Sr. National High School for the academic year 2024–2025. It also aimed to examine…
View details →DOI: 10.69651/pijhss0403392 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Muzaffar Ali, Deepak Padmanabhan, Khalil Kanjwal et al. · 2021 · Journal of Arrhythmia
Abstract Background Fluoroscopic imaging involves exposure of the patients and the laboratory staff to ionizing radiation. One of the strategies that reduce such exposure in an electrophysiology laboratory is using a three‐dimensional electroanatomic mapping (3D EAM) system for performing these procedures. In this analysis, we have analyzed the effect of fluoroscopy frame rate on the radiation exposure and in‐hospital outcomes in ablation procedures performed under 3D EAM guidance. Methods We retrospectively analyzed all the ablation procedures performed under 3D EAM guidance at our institute
View details →DOI: 10.1002/joa3.12496 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Chen Xinyan, Wu Yajie, He Shangfan et al. · 2025 · Nutrition & Metabolism
Abstract Intermittent fasting (IF) as a dietary intervention with potential health benefits has garnered significant attention in recent years. This study investigated the effects of varying fasting intensities on skeletal muscle growth using mouse models. Compared to the normal-diet (ND) control group, short-term fasting induced feeding amount-dependent alterations in skeletal muscle autophagy markers, characterized by elevated LC3B expression, reduced p62 levels, and decreased p-mTOR/mTOR ratio. Notably, short-term mild fasting (sMF) significantly upregulated myogenic (MYH, MyoD) and adipoge
View details →DOI: 10.1186/s12986-025-01001-3 Negative / Null Result ReportOpen accessMedicine
Hakan Hasman, Orhan Cinar, Ahmet Uzun, Erdem Cevik, Loni Jay, Bilgin Comert · 2012 · International Journal of Medical Sciences
Study objective: To compare the effect of normal saline (NS), lactated Ringer's, and Plasmalyte on the acid-base status of dehydrated patients in the emergency department (ED). Method: We conducted a prospective, double-blind, randomized trial of consecutive adult patients who presented to the emergency department with moderate-severe dehydration. Patients were randomly allocated to blindly receive normal saline (NS), lactated Ringer's or Plasmalyte at 20 ml/kg/h for 2 hours. Outcome measures of the study were pH and changes in electrolytes, including serum potassium, sodium, chloride and bica
Negative / Null Result ReportOpen accessAgriculture
José Antonio Suárez Lepe, Carlos Anibal Uthurry · 2007 · OENO One
Aims: Ethyl carbamate (EC) is a toxic compound of major concern for the hygiene quality of wines. Its natural synthesis in wine is connected to the ethanolysis of molecules such as urea (alcoholic fermentation metabolite) and citrulline and carbamyl phosphate (malolactic fermentation metabolites) during ageing. This study reports the effect of adenine, arginine, urea and ammonium phosphate of Vitis vinifera L. cv. Tempranillo must, on EC synthesis in fermented wine using two lactic acid bacteria strains under different microbiological and physicochemical conditions. Methods and results: EC was
View details →DOI: 10.20870/oeno-one.2007.41.4.842 