A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21697 results · page 205 of 724
Burke ND, Anderson AL, Schjenken JE et al. · 2026 · Preprint
ABSTRACT Capacitation, the process whereby sperm gain the functional competence to fertilize an egg in the absence of de novo transcription and translation, is orchestrated by a hierarchy of kinases driving the phosphorylation of sperm…
Kang AJ, Tseng CH, Wei MY · 2026 · The journals of gerontology. Series A, Biological sciences and medical sciences
Background Accurate case ascertainment of chronic conditions is critical for research, clinical decision-making, and population health management, especially for older adults with high multimorbidity. However, validation of ICD-based case…
Joy N, Soslow JH, Crum K et al. · 2026 · Cardiology in the young
Background Pulmonary valve replacement may be required for patients with pulmonary valve disease. Exertional symptoms related to cardiovascular disease are an indication for pulmonary valve replacement; however, quantification of symptom…
Boscariol R, Tressoldi P · 2026 · Preprint
This preregistered study is a replication and extension of prior exploratory work comparing an Intuition Market (IM) with a traditional Prediction Market (PM) in forecasting binary financial outcomes. A previous exploratory study suggested…
Csonka LL, Tikkakoski A, Karjalainen J et al. · 2026 · Clinical physiology and functional imaging
Background Peak expiratory flow (PEF) obtained from dedicated PEF meters and various types of spirometers is often used interchangeably in research, despite differences in both devices and expiratory maneuver technique. The aim of this…
Tang L, Sun C, Chen Z et al. · 2026 · Preprint
Abstract Background This study aimed to investigate the effects of curcumin supplementation and aerobic exercise on delaying age-related skeletal muscle atrophy and to further explore their potential synergistic effects. The findings are…
Aghdam EB, Romeralo C, Knapp DG et al. · 2026 · Preprint
Abstract Soilborne oomycetes of the genus Phytophthora are an increasing concern in European beech ( Fagus sylvatica ) forests, where they can damage root systems and contribute to tree decline. Because Phytophthora inoculum may persist in…
Parmar A, Saini N, Chhatre A et al. · 2026 · Preprint
Abstract Smartphone GNSS receivers are increasingly relied upon for location-dependent workflows in surveying, citizen science, agriculture, forestry, and field-based environmental data collection. The release of raw GNSS measurements…
Wadington M, Eklund K, Kilgus SP et al. · 2026 · School psychology (Washington, D.C.)
Research highlights the importance of the early identification of social, emotional, and behavioral concerns in young children; however, there are limitations regarding the usability and technical adequacy of available measures. The…
Tsuboi R, Murakami S, Miyata M et al. · 2026 · Preprint
Abstract BACKGROUND Dysphagia in Parkinson’s disease (PD) increases aspiration pneumonia risk and is associated with poor prognosis. Although subthalamic nucleus deep brain stimulation (STN-DBS) effectively treats motor symptoms, dysphagia…
Liao Y, Zhan L, Li H · 2026 · Basic & clinical pharmacology & toxicology
This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) collected between 1999 and 2018, enrolling a total of 4525 children and adolescents aged 6-15 years. Weighted logistic regression,…
Ashraf S, Ismail T, Akhtar S et al. · 2026 · Ultrasonics sonochemistry
Phyllanthus emblica L. (amla) is a medicinal fruit, rich in secondary metabolites with reported anti-inflammatory and antimicrobial effects. The current study aimed to assess the impact of drying and extraction techniques on phytochemical…
Krishna J, Khan Z, Chandra Y et al. · 2026 · Journal of nephrology
The epidemiology of kidney diseases is poorly known in several settings, including the Pacific Islands. To contribute to filling this gap, the current study aims to explore the incidence, distribution and patterns of biopsy-proven…
Hattori T, Hamaguchi M, Hashimoto Y et al. · 2026 · Diabetes, obesity & metabolism
Background In type 2 diabetes, impaired glucagon action in the liver (hepatic glucagon resistance) may disrupt the liver-α-cell axis. We examined the associations of fasting glucagon and a modified glucagon-alanine index (GAI) with…
Yahanda AT, Joseph K, Bui TT et al. · 2026 · Spine deformity
Purpose Surgical corrections for adult spinal deformity (ASD) often extend from T4-pelvis. Certain patients may require fusion from C2-pelvis. Comparisons are necessary to guide surgical decision-making, particularly for frailer patients…
Xu P, Li Y, Chen Y et al. · 2026 · Preprint
Background: Moderate-to-severe preterm brain injury (PBI), including intraventricular hemorrhage (IVH) and periventricular leukomalacia (PVL), remains an important cause of adverse neurodevelopmental outcomes in preterm infants. Early risk…
Mitchell WJ, Schmidt H, Moughan E et al. · 2026 · Preprint
Continuous self-report during ongoing experience provides a high-resolution window into subjective processing, yet concerns that it may disrupt the neural and cognitive processes being measured have limited its use in neuroimaging. We…
Bülbül N, Çiftçi R, Atik İ et al. · 2026 · Healthcare (Basel, Switzerland)
Background/Objectives: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder associated with substantial long-term morbidity and mortality. Routinely collected anthropometric, biochemical, and hematological variables may…
Ziva A, Ziori E, Pothos EM · 2026 · Quarterly journal of experimental psychology (2006)
Implicit (unconscious) learning ostensibly affects cognitive and social skills in both typical and atypical populations, such as those on the autism spectrum. Research into implicit learning in autism has yielded conflicting results,…
Newman EL, Mashanova-Galikova I, Tiganj Z et al. · 2026 · Hippocampus
Spatial tuning is a hallmark property of neural firing in the hippocampal formation. Yet, that tuning is often less well correlated with the instantaneous current position of an animal than it is with an integrated version of the past or…
Agboola OE, Agboola SS, Shaleye AB et al. · 2026 · Journal of molecular graphics & modelling
Predicting drug-target interactions computationally is a practical strategy for prioritizing candidate compounds in early drug discovery, but the reliability of published models is often limited by small resampled datasets, warm-only…
Pasotti F, Da Molin S, Bosoni T et al. · 2026 · Clinica chimica acta; international journal of clinical chemistry
Serum free light chains (FLC) κ and λ, and the κ/λ ratio, are key biomarkers for the diagnosis, risk stratification and monitoring of monoclonal gammopathies. However, substantial between-method variability still limits harmonised…
Neiling SL, Alt M, Kapa LL · 2026 · Language, speech, and hearing services in schools
Background The current project was a prospective feasibility study using a dynamic assessment of statistical learning of a novel morpheme for the identification of developmental language disorder (DLD) in Spanish-English-speaking…
Ren X, Dai Q, Jin C · 2026 · Journal of intensive care
Background Existing biomarker studies profile plasma during acute illness, leaving pre-illness proteomic susceptibility to critical care largely uncharacterised. We mapped the baseline proteomic architecture of critical-care outcomes in UK…
Diamantino GML, Beeler-Marfisi J, Foster RA et al. · 2026 · Veterinary pathology
The objective of this study was to evaluate the effect of different fixatives and demineralizers on immunohistochemical (IHC) detection of antigens in bone marrow (BM). Sternal BM samples were collected within 24 hours of death from dogs…
Xu P, Li Y, Chen Y et al. · 2026 · Children (Basel, Switzerland)
Background Moderate-to-severe preterm brain injury (PBI), including intraventricular hemorrhage (IVH) and periventricular leukomalacia (PVL), remains an important cause of adverse neurodevelopmental outcomes in preterm infants. Early risk…
Pratt AS, Ramos MN, Peña ED et al. · 2026 · Journal of speech, language, and hearing research : JSLHR
Purpose This study attempts to discriminate developmental language disorder (DLD) in bilinguals using only the child's second language (L2), English. We grouped bilinguals by their current weekly language experience (high English…
Wade ML, Litvak MK · 2026 · Zebrafish
Cryopreservation enables the long-term storage of viable biological material at ultra-low temperatures and forms the foundation for germplasm cryobanks that maintain valuable genetic lines of model organisms such as zebrafish ( Danio rerio…
Xu J, Ashebir YA, Shao Y · 2026 · Genes
Background: The dual agonism of glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) becomes a groundbreaking treatment for type 2 diabetes (T2D) that achieves robust glycemic control…
Nguyen Van H, Vu Dang L, Nguyen The A et al. · 2026 · Preprint
Objectives: Histologic grade is an important prognostic factor in hepatocellular carcinoma (HCC). Gd-EOB-DTPA-enhanced MRI may provide noninvasive im-aging markers related to tumour differentiation. This study aimed to evaluate the…