A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19821 results in Negative / Null Result Report · page 192 of 661
Awadallah M, Singh A, Hale GL et al. · 2026 · Case reports in transplantation
Hepatitis E virus (HEV) infection is an increasingly recognized cause of acute and chronic hepatitis in immunosuppressed individuals, including solid organ transplant recipients. Although typically self-limited in immunocompetent hosts,…
Yoon HJ, Kim GC, Nam SH · 2026 · Pathogens (Basel, Switzerland)
Background Oral candidiasis is an opportunistic infection caused by Candida albicans (C. albicans) , highlighting the need to evaluate candidate substances that ensure both antifungal efficacy and mucosal safety. This study aimed to assess…
Carretero D, Giménez E, Pérez A et al. · 2026 · Enfermedades infecciosas y microbiologia clinica (English ed.)
Introduction Studies assessing SARS-CoV-2 antibodies and functional T-cell responses in hematological patients following receipt of a three-dose mRNA vaccine schedule have yielded conflicting results. Methods We conducted a retrospective…
Chmielewska B, Marzec M, Szarejko I et al. · 2026 · Plant Science.
Root hairs, tubular extensions of the rhizodermal cells, facilitate nutrient uptake, yet their role in water acquisition remains debated and may be species- and soil-specific. To elucidate the genetic basis of root hair development and…
Zaryczańska A, Sokołowska-Wojdyło M, Wilkowska A et al. · 2026 · Contact dermatitis
Background Chronic exposure to topical corticosteroids (TCS) in patients with atopic dermatitis (AD) may increase the risk of allergic contact dermatitis (ACD), which can mimic flares of the underlying disease and remain underrecognized.…
Baneman E, Jacobs SE, Rana M et al. · 2026 · Clinical lymphoma, myeloma & leukemia
Background Cytomegalovirus (CMV) is an opportunistic pathogen that causes infection in certain immunocompromised hosts, but the risk of clinically significant CMV infection in patients with multiple myeloma (MM) is not well understood.…
Srivastava A, Maienschein-Cline M, Pabalan A et al. · 2026 · Methods (San Diego, Calif.)
MicroRNAs (miRNAs) are promising biomarkers and therapeutic targets; however, reliable extracellular miRNA quantification by RT-qPCR depends on appropriate normalization, and no universal endogenous reference has been established. This…
Chen C, Qualls WA, Xue RD et al. · 2026 · Journal of economic entomology
The sterile insect technique (SIT) is increasingly used as an alternative or supplemental tool in the integrated mosquito management toolbox to protect human health worldwide. SIT programs targeting mosquitoes such as Aedes aegypti (L.)…
Buchkowski RW, Polussa A, Bradford MA · 2026 · Global change biology
Detecting changes in forest soil carbon stocks is critical for compiling national carbon budgets, yet remains challenging due to high spatial variability and relatively small temporal changes. Here, we use data from Canada's National…
Yun YJ, Moon C, Kim KH et al. · 2026 · Journal of clinical medicine
Background : Wearable powered gait orthoses offer a clinically flexible alternative to treadmill-based robotic systems, yet evidence on different device configurations matched to the site of neuromuscular impairment remains limited.…
Li Y, Santer BD, Solomon S et al. · 2026 · Proceedings of the National Academy of Sciences of the United States of America
Large volcanic eruptions and intense wildfires perturb Earth's atmospheric temperature. Understanding the climate response to such natural forcings is essential for obtaining reliable estimates of its response to anthropogenic greenhouse…
Khan D · 2026 · Preprint
Abstract How social influence is organized in a networked group determines not only the accuracy of its collective estimate but also its vulnerability to deliberate steering. For a DeGroot-with-signals model of repeated estimation, the…
Paplauskas S · 2026 · Preprint
Local adaptation (LA) is expected to arise when populations evolve higher fitness in their local environment than migrants, particularly in heterogeneous environments and coevolving host–parasite systems. Such adaptation can influence…
Iribarren A, Obrutu O, Maughan J et al. · 2026 · American heart journal plus : cardiology research and practice
Background Caffeine, a nonselective adenosine A2 receptor antagonist, blunts adenosine-induced coronary hyperemia. Despite recommended abstinence before adenosine stress cardiac magnetic resonance imaging (CMRi), residual caffeine may…
Sivanandam P, Syenina A, Chan YF et al. · 2026 · Communications medicine
Background Mucosally-applied aminoglycosides have demonstrated host-directed antiviral activity in preclinical models through induction of interferon-stimulated genes (ISGs). However, it remains unknown if systemically administered…
Liu LT, Sun XS, Quan TT et al. · 2026 · Nature communications
Induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) is the standard treatment for locoregionally advanced nasopharyngeal carcinoma (LA-NPC); however, patients with a suboptimal response to IC, defined as detectable…
Němá K, Kačúr P, Kozák T et al. · 2026 · Journal of functional morphology and kinesiology
Background: Operational performance in security-force settings depends on maintaining accurate motor-cognitive and shooting performance under acute physical strain. This descriptive pilot study examined pre-post performance patterns during…
Rasmussen CA, Mink SB, Primdahl J et al. · 2026 · Musculoskeletal care
Introduction In recent years, the Ankylosing Spondylitis Performance Index (ASPI) has emerged as a new objective measure of physical function in patients with axial spondyloarthritis (axSpA). So far, only the relative interrater…
Moabelo KC, Rauh R, Loots A et al. · 2026 · Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
We evaluated the performance of the FMDV 2.1 dry RT-rtPCR prototype assay (Tetracore) to detect foot-and-mouth disease virus (FMDV) in lymph nodes. Various masses (20-100 mg) of FMDV-negative lymph node tissue were homogenized, diluted,…
Arovah NI, Kushartanti W, Ambardini RL · 2026 · Rehabilitacion
Background and objective Nonspecific low back pain (NSLBP) is a prevalent musculoskeletal condition. This study examined the immediate effects of extracorporeal shockwave therapy (ESWT), ultrasound therapy (UST), and shortwave diathermy…
Kumpas G, Brewer B · 2026 · Preprint
Abstract Between 1976 and 2016, most U.S. states adopted laws authorizing or requiring police to make warrantless arrests at the scene of a domestic violence call. These laws were intended to protect victims, but they may also deter…
Cherenack EM, Larson ME, Roach ME et al. · 2026 · Brain, behavior, and immunity
Background Limited research has examined the longitudinal interplay of depression, substance use, and immune dysregulation among men with HIV. Methods We analyzed longitudinal data from 100 men who have sex with men (MSM) living with HIV…
Hoehne C, Rehling S, Schrenker J et al. · 2026 · Scientific reports
Preclinical simulation is essential for students to practice before clinical treatment. A low-cost 3D-printed model was developed with repositionable mobile maxillary anterior teeth to train periodontal splinting and evaluate learner…
Tozawa R, Ishii N, Minamoto Y · 2026 · Cureus
Background Medial meniscus extrusion (MME) is a pivotal biomarker for knee osteoarthritis progression. Although ultrasonography offers a dynamic and cost-effective MME assessment, its clinical utility is often limited by the perceived high…
Stein A · 2026 · Preprint
Abstract Low-dose radiation epidemiology is contested and inconclusive: confidence intervals span zero, and point estimates shift with the chosen dose range. Part of the contest is structural, not empirical. Under the linear…
Arslan SG, Gultekinler BD · 2026 · BMC sports science, medicine & rehabilitation
Background Force platforms are widely used to assess postural stability and vertical jump performance, yet their cost and limited portability restrict routine clinical and field-based use. The Meloq EasyBase force platform offers a…
Pisani M, Marcheschi P, Clemente A et al. · 2026 · Preprint
Aortic calcification represents a key marker of cardiovascular disease, detectable through medical imaging. This research investigates the use of artificial intelligence (AI) to assist radiologists in identifying aortic calcification in…
Liang A, Veetil S, Groom K et al. · 2026 · Preprint
Abstract Laser Powder Bed Fusion (LPBF) is a widely adopted additive manufacturing technique for producing geometrically metal components. While this process yields fine microstructures beneficial for strength, the associated rapid thermal…
Ware A, LaMountain J, White RC et al. · 2026 · Nature communications
The electromagnetic response of materials serves as the foundation for a broad range of vital applications, from imaging, to sensing, to classical and quantum communications. Here we demonstrate, theoretically and experimentally, a…
Ajibola G, Nelson BS, Niesar A et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Broadly neutralizing antibodies (bNAbs) are a promising treatment option for children with HIV-1, but their long-term impact on virologic, immunologic, and clinical outcomes is unknown. Methods The Tatelo Study investigated dual…