Methylation-based droplet digital polymerase chain reaction shows high concordance with chronic lymphocytic leukemia IGHV somatic mutation status.
Sabatini P; Zhang T; Boruvka N; Kim HS; Feilotter H; Stockley T; Chen C; Xia D · 2025 · American journal of clinical pathology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Objective Somatic hypermutation at immunoglobulin heavy chain variable (IGHV) genes, an established prognostic and predictive biomarker for chronic lymphocytic leukemia (CLL), is assessed by gene sequencing. We developed a single…
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Metadata source: Europe PMC · DOI 10.1093/ajcp/aqaf075