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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21697 results · page 185 of 724

Negative / Null Result Report

Thalassemia and assisted reproduction: non-transfusion-dependent thalassemia shows no significant effect on live birth rates after embryo transfer

Li Fan, Liuyan Wei, Ni Tang et al. · 2025 · Frontiers in Cell and Developmental Biology

Background Thalassemia is a hereditary blood disorder that can impact fertility due to various factors such as iron overload and endocrine disruption. While the effects of iron overload on fertility outcomes in transfusion-dependent…

View details →DOI: 10.3389/fcell.2025.1573572Cited by 3
Negative / Null Result Report

The wild goat of Montecristo Island: did it ever exist?

Spartaco Gippoliti · 2016 · Mammalia

Abstract It has recently been claimed by Masseti that a wild goat survived on Montecristo Island until the first half of the 20th century and that subsequent selection procedures produced a goat that did not resemble any true wild goat. In…

View details →DOI: 10.1515/mammalia-2015-0078Cited by 2
Negative / Null Result Report

Carotid artery stenting using CASPER has a lower incidence of ischemic complications compared to Carotid WALLSTENT, but there is no significant difference in postoperative restenosis

Takashi Fujii, Shuta Maehara, Yoshimasa Fukui et al. · 2025 · Interventional Neuroradiology

Background The usefulness of CASPER, a second-generation carotid stent, for carotid artery stenosis is becoming increasingly clear. However, few studies have directly compared treatment outcomes with those of the first-generation Carotid…

View details →DOI: 10.1177/15910199251347774Cited by 2
Negative / Null Result Report

ANALISIS KEMAMPUAN CALON GURU DALAM MENGEMBANGKAN MEDIA PEMBELAJARAN

Ines Tasya Jadidah, Eby Sania Awalia, Althaafi Abdillah et al. · 2023 · SIGNIFICANT : Journal Of Research And Multidisciplinary

Tujuan penelitian ini dilakukan agar dapat menganalisa kemampuan calon guru dalam mengembangkan media pembelajaran. Penelitian ini menggunakan penelitian kualitatif deskrpitif yang intrumen nya berupa observasi untuk memperoleh suatu…

View details →DOI: 10.62668/significant.v1i02.658Cited by 2
Negative / Null Result Report

Reduction in distraction due to perceptual load: A failure to replicate

Robert J. Snowden, Nicola S. Gray · 2025 · Perception

Perceptual load theory states that there are limited processing resources, but that these must always be fully employed. It has been used to predict and explain the commonly reported finding that irrelevant distractors influence behaviour…

View details →DOI: 10.1177/03010066251364203Cited by 2
Negative / Null Result Report

Ultrasound-guided supraclavicular nerve block for implantable port catheters: Does it show a significant difference in pain control?

Emre Can Çelebioğlu, Mehmet Sadık Bilgiç · 2021 · The Journal of Vascular Access

Background: Nerve blocks have been used for decades at head and neck region interventions and recently introduced as an alternative option for subcutaneous port implantation. This study aimed to compare two different local anesthesia…

View details →DOI: 10.1177/1129729820987358Cited by 2
Negative / Null Result Report

Lack of significant effect of interleukin-18 gene variants on tuberculosis susceptibility in the Polish population

Sebastian Wawrocki, Grzegorz Kielnierowski, Wieslawa Rudnicka et al. · 2019 · Acta Biochimica Polonica

Background: Polymorphisms in genes encoding cytokines are known to determine susceptibility to Mycobacterium tuberculosis (M.tb) infection. In particular, interleukin-18 (IL-18), an inducer of interferon-gamma (IFN-γ), playing an important…

View details →DOI: 10.18388/abp.2019_2797Cited by 2
Negative / Null Result Report

NO SIGNIFICANT EFFECT OF 3D MODELLING ON SURGICAL PLANNING IN SPINAL DEFORMITIES

Ortac Guran, Hakan Oflaz, İzge Gunal · 2022 · Acta Ortopédica Brasileira

ABSTRACT Objective: To evaluate the effect of 3d printed models on surgical pre-operative planning of complex spinal deformities. Methods: In our study, five orthopedic surgeons made surgical planning of 5 patients with severe spinal…

View details →DOI: 10.1590/1413-785220223001e248982Cited by 2
Negative / Null Result Report

Significant effect of SDS on the optimum operating temperature of ZnO nanosheets gas-sensitive materials

Hai Yu, Xiaoqi Yu, Chengyou Liu et al. · 2022 · The European Physical Journal Applied Physics

Many methods have been used to reduce the operational energy consumption of ZnO gas-sensitive material effectively. In this paper, different morphologies of ZnO nanomaterials are prepared in the anionic hydrophilic surfactant sodium lauryl…

View details →DOI: 10.1051/epjap/2021210247Cited by 2
Negative / Null Result Report

Employing Cluster Analysis to Detect Significant Cloud 3D RT Effect Indicators

Michael J. Foster, Dana E. Veron · 2010 · Journal of the Atmospheric Sciences

Abstract Three-dimensional cloud field morphology contributes to scene-averaged cloud reflectivity, but climate models do not currently incorporate methods of identifying situations where this contribution is substantial. This work…

View details →DOI: 10.1175/2010jas3414.1Cited by 2
Negative / Null Result Report

How Did Early Modern Scholars Study Early Maps?

Matthew H Edney · 2024 · Cartographic Perspectives

The two standard Anglophone historiographies of the history of cartography (Skelton 1972, Harley 1987) situated the field’s origins in the early modern era, or even in the later Middle Ages. Yet “history” and “cartography” are both…

View details →DOI: 10.14714/cp105.1881Cited by 2
Negative / Null Result Report

A real life retrospective analysis of drug expenditure reveals no significant cost difference between infliximab and adalimumab in the treatment of adult crohn's disease: Figure 1

C A Lamb, M Price, M Robinson et al. · 2011 · Gut

Introduction The revised NICE guidance on the use of infliximab and adalimumab for the treatment of Crohn's disease, released in May 2010, has suggested biologics be prescribed as a planned therapy until treatment failure or until…

View details →DOI: 10.1136/gut.2011.239301.534Cited by 2
Failed Experiment Report

Significant Enhancement of Electrocaloric Effect in Ferroelectric Polymer via Nanopores Interfacial Engineering

Youhao Xiong, Zilong Xie, Sen Xue et al. · 2025 · Advanced Functional Materials

Abstract Ferroelectric polymer‐based electrocaloric (EC) materials are promising for next‐generation solid‐state refrigeration due to their high entropy change, eco‐friendliness, lightweight, and flexibility. The practical application of…

View details →DOI: 10.1002/adfm.202507417Cited by 2
Negative / Null Result Report

Failed Intrauterine Pregnancy: What Is a Failed Pregnancy, What Is Not?

TIMOTHY P. CANAVAN · 2017 · Clinical Obstetrics & Gynecology

Pregnancy failure is defined as a lack of sonographic evidence of current or expected viability. Technologic advances in ultrasound imaging continue to redefine diagnostic criteria of pregnancy failure or success. When evaluating a…

View details →DOI: 10.1097/grf.0000000000000301Cited by 2
Negative / Null Result Report

Britain’s Failed Attempt at Monetary and Fiscal Exceptionalism

David Marsh · 2023 · The Economists’ Voice

Abstract The autumn 2022 economic upheavals that brought down British Prime Minister Liz Truss’s government represented an ultimate extension of a high-risk exercise in British exceptionalism: the June 2016 referendum decision to leave the…

View details →DOI: 10.1515/ev-2023-0021Cited by 2
Negative / Null Result Report

Modulated stimuli demonstrate asymmetric interactions between hearing and vision

Quoc C. Vuong, Mark Laing, Anjana Prabhu et al. · 2019 · Scientific Reports

Abstract The nature of interactions between the senses is a topic of intense interest in neuroscience, but an unresolved question is how sensory information from hearing and vision are combined when the two senses interact. A problem for…

View details →DOI: 10.1038/s41598-019-44079-5Cited by 2
Negative / Null Result Report

A case report about adalimumab-induced radiologically isolated syndrome: A significant side effect of tumour necrosis factor inhibitors

Joshua Onasanya, Renée A Beach · 2021 · SAGE Open Medical Case Reports

Tumor necrosis factor-α antagonists have become a therapeutic mainstay for various inflammatory diseases including Hidradenitis Suppurativa. Despite their clinical efficacy, these medications have been associated with the rare development…

View details →DOI: 10.1177/2050313x211003057Cited by 2
Negative / Null Result Report

The small impact of p-hacking marginally significant results on the meta-analytic estimation of effect size

Juan Botella, Manuel Suero, Juan I. Durán et al. · 2021 · Anales de Psicología

La etiqueta p-hacking (pH) se refiere a un conjunto de prácticas oportunistas destinadas a hacer que sean significativos algunos valores p que deberían ser no significativos. Algunos han argumentado que debemos prevenir y luchar contra el…

View details →DOI: 10.6018/analesps.433051Cited by 2
Negative / Null Result Report

Variations in Polysomnographic Indices of Obstructive Sleep Apnea following Lingual Tonsil Hypertrophy Excision: Is the Difference Significant?

Ashraf Wahba, Khaled Abdelaal, Ayman Yehia et al. · 2022 · Medicina

Background and Objectives: Obstructive sleep apnea (OSA) is a sleep-related respiratory disorder that affects between 5% and 20% of the population. In obstructive sleep apnea, lingual tonsillar hypertrophy (LTH) has been suggested as a…

View details →DOI: 10.3390/medicina58050573Cited by 2
Negative / Null Result Report

Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV

Rahul Sampath, Nathan W. Cummins, Andrew D. Badley · 2016 · Journal of Cell Death

HIV cure is now the focus of intense research after Timothy Ray Brown (the Berlin patient) set the precedent of being the first and only person cured. A major barrier to achieving this goal on a meaningful scale is an elimination of the…

View details →DOI: 10.4137/jcd.s39872Cited by 2
Negative / Null Result Report

Failure to Replicate: A Sign of Scientific Misconduct?

Helene Hill, Joel Pitt · 2014 · Publications

Repeated failures to replicate reported experimental results could indicate scientific misconduct or simply result from unintended error. Experiments performed by one individual involving tritiated thymidine, published in two papers in…

View details →DOI: 10.3390/publications2030071Cited by 2
Negative / Null Result Report

Less risk of patellofemoral degeneration without significant clinical and survivorship difference for distal tibial tuberosity high tibial osteotomy compared to biplanar high tibial osteotomy over a mid-term follow-up

Ke Li, Hengbing Guo, Fenglong Sun et al. · 2024 · Journal of Orthopaedic Surgery

Purpose This study aims to compare the mid-term radiographic, clinical results and survivorship between distal tibial tuberosity high tibial osteotomy (DTT-HTO) and conventional biplanar medial open-wedge high tibial osteotomy (cOW-HTO).…

View details →DOI: 10.1177/10225536241273925Cited by 2
Negative / Null Result Report

Dataset of replicate Apollo sample magnetizations bearing on impacts and absence of a long-lived lunar dynamo

Rory D. Cottrell, Tinghong Zhou, John A. Tarduno · 2024 · Scientific Data

Abstract The absence or presence of a lunar paleomagnetosphere is important because it bears directly on the volatile content of the regolith and exploration targets for Artemis and other missions to the Moon. Recent paleointensity study…

View details →DOI: 10.1038/s41597-024-03626-0Cited by 2
Negative / Null Result Report

Validation of an ampicillin selection protocol to enrich for mutants of Listeria monocytogenes unable to replicate on fresh produce

Victor Jayeola, C Parsons, L Gorski et al. · 2019 · FEMS Microbiology Letters

ABSTRACT Several outbreaks of listeriosis have implicated fresh produce but genetic factors required for growth of Listeria monocytogenes on produce remain poorly characterized. Based on the fact that β-lactam antibiotics only kill…

View details →DOI: 10.1093/femsle/fnz076Cited by 2