A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20217 results in Negative / Null Result Report · page 177 of 674
Victor Jayeola, C Parsons, L Gorski et al. · 2019 · FEMS Microbiology Letters
ABSTRACT Several outbreaks of listeriosis have implicated fresh produce but genetic factors required for growth of Listeria monocytogenes on produce remain poorly characterized. Based on the fact that β-lactam antibiotics only kill…
Quoc C. Vuong, Mark Laing, Anjana Prabhu et al. · 2019 · Scientific Reports
Abstract The nature of interactions between the senses is a topic of intense interest in neuroscience, but an unresolved question is how sensory information from hearing and vision are combined when the two senses interact. A problem for…
Helene Hill, Joel Pitt · 2014 · Publications
Repeated failures to replicate reported experimental results could indicate scientific misconduct or simply result from unintended error. Experiments performed by one individual involving tritiated thymidine, published in two papers in…
Maria Daniela Silva, Graça Pinto, Angela França et al. · 2024 · mSystems
ABSTRACT In nature, bacteria often survive in a stationary state with low metabolic activity. Phages use the metabolic machinery of the host cell to replicate, and, therefore, their efficacy against non-dividing cells is usually limited.…
Matthew H Edney · 2024 · Cartographic Perspectives
The two standard Anglophone historiographies of the history of cartography (Skelton 1972, Harley 1987) situated the field’s origins in the early modern era, or even in the later Middle Ages. Yet “history” and “cartography” are both…
Joshua Onasanya, Renée A Beach · 2021 · SAGE Open Medical Case Reports
Tumor necrosis factor-α antagonists have become a therapeutic mainstay for various inflammatory diseases including Hidradenitis Suppurativa. Despite their clinical efficacy, these medications have been associated with the rare development…
Sebastian Wawrocki, Grzegorz Kielnierowski, Wieslawa Rudnicka et al. · 2019 · Acta Biochimica Polonica
Background: Polymorphisms in genes encoding cytokines are known to determine susceptibility to Mycobacterium tuberculosis (M.tb) infection. In particular, interleukin-18 (IL-18), an inducer of interferon-gamma (IFN-γ), playing an important…
Jonathan R. Strand, Kenneth J. Retzl · 2016 · Development and Change
ABSTRACT Using the concept of good governance, this article assesses how voting rules in the World Bank Group's primary loan facility determine members’ ability to influence the formation of winning coalitions in the Executive Board. In…
Michael J. Foster, Dana E. Veron · 2010 · Journal of the Atmospheric Sciences
Abstract Three-dimensional cloud field morphology contributes to scene-averaged cloud reflectivity, but climate models do not currently incorporate methods of identifying situations where this contribution is substantial. This work…
Ortac Guran, Hakan Oflaz, İzge Gunal · 2022 · Acta Ortopédica Brasileira
ABSTRACT Objective: To evaluate the effect of 3d printed models on surgical pre-operative planning of complex spinal deformities. Methods: In our study, five orthopedic surgeons made surgical planning of 5 patients with severe spinal…
Mika Moriwaki, Corrine Kolka Welt · 2021 · Journal of the Endocrine Society
Abstract We identified a stop-gain mutation in eIF4ENIF1 in a family in which multiple women developed primary ovarian insufficiency (POI) at approximately age 30 years. We hypothesized that the same mutation in a mouse model would…
Cheng-Hua Yang, Alex · 2015 · Journal of Air Transport Studies
Aviation safety has been affected greatly by technological improvements. A series of Ground Proximity Warning Systems (GPWSs) were developed to prevent accidents during Controlled Flight into Terrain (CFIT). This study analyzed the role of…
John W Walker, Brian M Shoemake, Danilo G Quadros et al. · 2023 · Journal of Animal Science
Abstract A sodium pentobarbital-induced sleep time study was conducted on 15 adult intact male Boer × Spanish goats selected for high (J+, n = 7) or low (J−, n = 8) juniper consumption (estimated breeding values of 13.1 ± 1.0 and −14.3 ±…
Hideyuki Yamamoto, Shotaro Hagiwara, Yuki Kojima et al. · 2011 · Blood
Abstract Abstract 1629 Background: With the widespread use of highly active antiretroviral therapy (HAART), the prognosis of HIV infected subjects has been improved, even if with AIDS-related lymphoma. Burkitt lymphoma progresses very…
Emre Can Çelebioğlu, Mehmet Sadık Bilgiç · 2021 · The Journal of Vascular Access
Background: Nerve blocks have been used for decades at head and neck region interventions and recently introduced as an alternative option for subcutaneous port implantation. This study aimed to compare two different local anesthesia…
Afroz Salman, Biranthabail Dhanashree, Himani Kotian · 2025 · Scientifica
The aim of this research is to investigate the antimicrobial characteristics of bacterial pigments. Pigments are vibrant metabolites generated by bacteria, offering defence against radiation, sunlight, stress and competing microorganisms.…
Ana Gabriela Pérez-Castillo, Weynner Giraldo-Sanclemente, Mayela Monge-Muñoz et al. · 2024 · Frontiers in Agronomy
Urea is widely used as nitrogen (N) source for rice fertilization in Costa Rica, despite its low efficiency linked to ammonia losses. To assess urea management alternatives, two field experiments were conducted in the Central Pacific…
Ashraf Wahba, Khaled Abdelaal, Ayman Yehia et al. · 2022 · Medicina
Background and Objectives: Obstructive sleep apnea (OSA) is a sleep-related respiratory disorder that affects between 5% and 20% of the population. In obstructive sleep apnea, lingual tonsillar hypertrophy (LTH) has been suggested as a…
Jacqueline Lubin, null null, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day
Research has shown there is a positive correlation between self-determination skills and quality of life of college students with autism spectrum disorder (ASD). The purpose of this literature review is to highlight research on…
Gavin Sim, Janet C Read · 2024 · Interacting with Computers
Abstract This study used eye-tracking glasses to better understand how children explore low-fidelity prototypes in the context of user experience studies and to explore the potential of eye tracking in this context. The main research…
Rahul Sampath, Nathan W. Cummins, Andrew D. Badley · 2016 · Journal of Cell Death
HIV cure is now the focus of intense research after Timothy Ray Brown (the Berlin patient) set the precedent of being the first and only person cured. A major barrier to achieving this goal on a meaningful scale is an elimination of the…
Rory D. Cottrell, Tinghong Zhou, John A. Tarduno · 2024 · Scientific Data
Abstract The absence or presence of a lunar paleomagnetosphere is important because it bears directly on the volatile content of the regolith and exploration targets for Artemis and other missions to the Moon. Recent paleointensity study…
Ke Li, Hengbing Guo, Fenglong Sun et al. · 2024 · Journal of Orthopaedic Surgery
Purpose This study aims to compare the mid-term radiographic, clinical results and survivorship between distal tibial tuberosity high tibial osteotomy (DTT-HTO) and conventional biplanar medial open-wedge high tibial osteotomy (cOW-HTO).…
Iván Sánchez-Iglesias, Celia Martín-Aguilar · 2023 · Journal of Clinical Medicine
Clinical trials are the backbone of medical scientific research. However, this experimental strategy has some drawbacks. We focused on two issues: (a) The internal validity ensured by clinical trial procedures does not necessarily allow…
C A Lamb, M Price, M Robinson et al. · 2011 · Gut
Introduction The revised NICE guidance on the use of infliximab and adalimumab for the treatment of Crohn's disease, released in May 2010, has suggested biologics be prescribed as a planned therapy until treatment failure or until…
Hai Yu, Xiaoqi Yu, Chengyou Liu et al. · 2022 · The European Physical Journal Applied Physics
Many methods have been used to reduce the operational energy consumption of ZnO gas-sensitive material effectively. In this paper, different morphologies of ZnO nanomaterials are prepared in the anionic hydrophilic surfactant sodium lauryl…
Juan Botella, Manuel Suero, Juan I. Durán et al. · 2021 · Anales de Psicología
La etiqueta p-hacking (pH) se refiere a un conjunto de prácticas oportunistas destinadas a hacer que sean significativos algunos valores p que deberían ser no significativos. Algunos han argumentado que debemos prevenir y luchar contra el…
Ines Tasya Jadidah, Eby Sania Awalia, Althaafi Abdillah et al. · 2023 · SIGNIFICANT : Journal Of Research And Multidisciplinary
Tujuan penelitian ini dilakukan agar dapat menganalisa kemampuan calon guru dalam mengembangkan media pembelajaran. Penelitian ini menggunakan penelitian kualitatif deskrpitif yang intrumen nya berupa observasi untuk memperoleh suatu…
H Kim, H-C Shin, CK Yom et al. · 2010 · Cancer Research
Abstract Purpose: CYP2D6 variant alleles have been suspected to influence on the clinical efficacy of tamoxifen because CYP2D6 is an enzyme which metabolizes tamoxifen into its active forms, endoxifen and 4-hydroxytomoxifen. This study was…
Borbála A. Lőrincz, Agustina Anson, Stephan Handschuh et al. · 2021 · Acta Veterinaria Hungarica
Abstract Hippocampal changes in epilepsy may manifest as hippocampal atrophy/sclerosis. A recent human study suggests that the demonstration of hippocampal volume loss is more reliable using quantitative evaluation methods. The aim of the…