Abstract PD05-08: Lack of Significant Association between CYP2D6 Polymorphisms and Clinical Outcomes of Adjuvnt Tamoxifen Therapy
H Kim; H-C Shin; CK Yom; S Ahn; H-G Moon; W Han; D-Y. Noh · 2010 · Cancer Research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Abstract Purpose: CYP2D6 variant alleles have been suspected to influence on the clinical efficacy of tamoxifen because CYP2D6 is an enzyme which metabolizes tamoxifen into its active forms, endoxifen and 4-hydroxytomoxifen. This study was…
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Metadata source: Crossref · DOI 10.1158/0008-5472.sabcs10-pd05-08