A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20217 results in Negative / Null Result Report · page 173 of 674
Xinrong Li, Yue Zhu, Maria Keaton et al. · 2020 · Bioscience Reports
Abstract A few studies suggested the contribution of PPARs to the etiology of schizophrenia (SCZ). However, it is still not clear whether variants in PPAR-encoding genes have a direct association with SCZ. The potential linkage between SCZ…
Andre Briosa e Gala, Michael T. B. Pope, Milena Leo et al. · 2024 · Journal of Arrhythmia
Abstract Introduction The novel Confirm Rx™ implantable cardiac monitor (ICM) with SharpSense™ technology incorporates a new P‐wave discriminator designed to improve AF detection. This study aimed to evaluate the diagnostic performance of…
Yueqi Wang, Shouming Chen, Ahmed Rabeeu · 2024 · Tourism Economics
Extant studies have found that the inscription of World Heritage sites (WHS) has no or negative effect on tourism in China, which does not explain why Chinese local governments are eager to apply for WHS. This study employs the…
Jenane Konesan, Kate H Moore, Kylie J Mansfield et al. · 2024 · Pathogens and Disease
Abstract Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), have an unclear impact on bladder mucosal physiology. This study investigates UPEC’s effects on the urothelium and lamina propria using an…
Li Fan, Liuyan Wei, Ni Tang et al. · 2025 · Frontiers in Cell and Developmental Biology
Background Thalassemia is a hereditary blood disorder that can impact fertility due to various factors such as iron overload and endocrine disruption. While the effects of iron overload on fertility outcomes in transfusion-dependent…
Andrew Tomkins, Sam Naylor, Emile Morgan · 2018 · International Journal of STD & AIDS
Did not attend (DNA) appointments create a significant impact upon resource and finance efficiency in the NHS. Despite introduction of short-message service (SMS) reminders to our patients, DNA rates remained persistently high. An option…
Vicktoria Elkarif, Leonid Kandel, Debbie Rand et al. · 2021 · Applied Sciences
We aimed to compare the spatiotemporal parameters and joint kinematics during unperturbed and perturbed gait between individuals with osteoarthritis (OA) who did or did not undergo total knee replacement (TKR) one year post a baseline…
Sunil Narayan, Adithan Chandrasekaran, Debdatta Basu et al. · 2020 · The Journal of Applied Laboratory Medicine
Abstract Background Prothrombotic factors have been correlated with vascular events in young patients, with recurrent strokes, and with venous thromboembolisms. However, their prevalence in adult strokes, in healthy populations, and in…
Adolor Aisiri, Babafunke Fagbemi, Oluseyi A. Akintola et al. · 2020 · African Evaluation Journal
Background: Childbirth spacing (CBS) or Family Planning (FP) methods are considered an essential component of sexual and reproductive health. It refers to the resting period between pregnancies that provides the mother with time to…
Anas Alkhofi · 2025 · Frontiers in Artificial Intelligence
This study compares the quality of English-to-Arabic translations produced by Google Translate (GT) with those generated by student translators. Despite advancements in neural machine translation technology, educators often remain…
Margaret Glogowska, Melissa Stepney, Stephen Rocks et al. · 2022 · Journal of Health Organization and Management
Purpose As part of an evaluation of the nationally mandated Child and Adolescent Mental Health Services (CAMHS) “transformation” in one foundation NHS trust, the authors explored the experiences of mental health staff involved in the…
Tonia-Flery Artemi, Thekla Konstantinou, Stephany Naziri et al. · 2025 · Virtual Worlds
Introduction: This study examines the combined use of objective physiological measures (heart rate [HR], heart rate variability [HRV]) and subjective self-reports to gain a comprehensive understanding of anxiety reduction…
Shengde Li, Li-Ying Cui, Craig Anderson et al. · 2020 · BMC Neurology
Abstract Background Cerebrovascular disease (CVD) survivors are at a high risk of recurrent stroke. Although it is thought that survivors with higher risk of stroke respond better to stroke onset, to date, no study has been able to…
Saif Uddin, Aysun U. Gorgun, Scott W. Fowler et al. · 2023 · Journal of Environmental Exposure Assessment
The concentration of 210Po and 210Pb in vegetation, and their transfer from soil to vegetation and via aerosol deposited on foliage are well established. The available data show significantly higher levels of these radionuclides in ash…
Olivia Rann, Mike Sharland, Paul Long et al. · 2017 · BMJ Open
Objectives Inaccurate antibiotic dosing can lead to treatment failure, fuel antimicrobial resistance and increase side effects. The British National Formulary for Children (BNFC) guidance recommends oral antibiotic dosing according to age…
Karen Crinall, Madeleine Ward, Rebecca McDonald et al. · 2022 · Evaluation Journal of Australasia
This article discusses the use of the Most Significant Change (MSC) technique in a mixed-methods evaluation of a pilot wellbeing programme for obstetrics and gynaecology doctors-in-training introduced at a large public hospital during…
Irina Rozgacheva · 2019 · Symmetry
The relatively high abundance of fractal properties of complex systems on Earth and in space is considered an argument in support of the general relativity of the geometric theory of gravity. The fractality may be called the fractal…
Dusadee Sarangarm, Gregory Lamb, Steven Weiss et al. · 2018 · JAMIA Open
Abstract Objectives To compare physician productivity and billing before and after implementation of electronic charting in an academic emergency department (ED). Materials and methods This retrospective, blinded, observational study…
Xiaoli Wu, Cuiting Wu, Tao Zhou · 2023 · Brain and Behavior
Abstract Objectives N 6 ‐methyladenosine (m 6 A) plays a crucial role in regulating neuroplasticity and different brain functions at the posttranscriptional level. However, it remains unknown whether m 6 A modification is involved in acute…
Johanna Dahan, Jehonathan Pinthus, Guila Delouya et al. · 2024 · BMC Urology
Abstract Introduction Several blood markers of inflammation are elevated in prostate cancer (PCa) and have prognostic value. Little is known about the relationship between these markers, PCa, and other factors associated with chronic…
Hui Wang, Yu’e Zhang, Yudan Chen et al. · 2024 · Agronomy
To understand the genetic basis of soybean sulfur utilization, a genome-wide association study (GWAS) and transcriptome analysis were used to discover new sulfur utilization genes in 121 wild soybeans. The shoot sulfur accumulation (SA)…
Bonnie Amelia Dean, Kate Tubridy, Michelle J Eady et al. · 2024 · Journal of Teaching and Learning for Graduate Employability
Higher education plays a key role in cultivating graduate employability, which is essential to meeting multiple individual, community, social and labour market needs. Universities prioritise employability through strategic goals and…
James Wan, Raafat Saade, Ling Wang · 2019 · Journal of Organizational Change Management
Purpose A consequence of the UN general assembly resolution calling for increased efficiency and better utilization of resources in all its agencies, is a mandate for change. As a response to this resolution, the purpose of this paper is…
Zahra Dashti, Vahid Razban, Jafar Fallahi et al. · 2025 · Egyptian Journal of Medical Human Genetics
Abstract Background Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine and metabolic disorders, affecting approximately 15% of females. This syndrome is characterized by its remarkable heterogeneity, and epigenetic…
Vusani Moyo, Fidelis Mache · 2018 · Journal of Applied Business Research (JABR)
A number of surveys reveal that a large number of analysts, valuation experts, investors, chief financial officers and finance academics employ the capital asset pricing model (CAPM) of Sharpe (1962) and Lintner (1965) to estimate the cost…
Jin Shang, Shigeyuki Hamori · 2023 · Journal of Risk and Financial Management
With the continuous advancement of machine learning and the increasing availability of internet-based information, there is a belief that these approaches and datasets enhance the accuracy of price prediction. However, this study aims to…
Victorine H. Roos, Frank G. J. Kallenberg, Manon van der Vlugt et al. · 2020 · British Journal of Cancer
Abstract Background Faecal immunochemical testing (FIT) is suboptimal in detecting advanced neoplasia (AN). To increase the sensitivity and yield of a FIT-based screening programme, FIT could be combined with risk factors for AN. We…
Abdel Razzaq Al Rababa’a, Zaid Saidat, Raed Hendawi · 2021 · Investment Management and Financial Innovations
Different models have been used in the finance literature to predict the stock market returns. However, it remains an open question whether non-linear models can outperform linear models while providing accurate predictions for future…
Miki Okuno, Kentaro Matsuoka, Yuta Mochimaru et al. · 2025 · Molecular Biology and Evolution
Abstract The XX/XY sex chromosome system is highly conserved across mammals, with rare exceptions where males lack a Y chromosome. Among these is the genus Tokudaia, a group of spiny rats comprising three species with unique sex chromosome…
Barbara Stypińska, Marzena Olesińska, Andrzej Pawlik et al. · 2018 · Rheumatology
Objectives Rheumatoid arthritis (RA) is the most common systemic inflammatory disease and is of unknown etiology. The altered balance between immunosuppressive and inflammatory T cell subpopulations exerts a huge impact on RA pathogenesis.…