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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20217 results in Negative / Null Result Report · page 166 of 674

Negative / Null Result Report

Beta‐alanine did not improve high‐intensity performance throughout simulated road cycling

Pedro Perim, Nathan Gobbi, Breno Duarte et al. · 2021 · European Journal of Sport Science

ABSTRACT This study investigated the effect of beta‐alanine supplementation on short‐duration sprints and final 4‐km simulated uphill cycling time‐trial performance during a comprehensive and novel exercise protocol representative of the…

View details →DOI: 10.1080/17461391.2021.1940304Cited by 7
Negative / Null Result Report

Long‐chain alcohols did not improve predictions of the composition of tall fescue and red clover mixtures over n ‐alkanes alone

N. Vargas Jurado, A. E. Tanner, S. R. Blevins et al. · 2014 · Grass and Forage Science

Abstract Feed intake and diet choice affect production efficiency in livestock. Plant waxes, in particular n ‐alkanes, have been used as markers to predict intake and diet preferences. Still, when n ‐alkane profiles of plants within mixed…

View details →DOI: 10.1111/gfs.12134Cited by 7
Negative / Null Result Report

Normocalcaemic hyperparathyroidism and primary hyperparathyroidism: least significant change for adjusted serum calcium

Marian Schini, Richard Jacques, Eleanor Oakes et al. · 2021 · European Journal of Endocrinology

Introduction The least significant change (LSC) is a term used in individuals in order to evaluate whether one measurement has changed significantly from the previous one. It is widely used when assessing bone mineral density (BMD) scans.…

View details →DOI: 10.1530/eje-20-0634Cited by 7
Negative / Null Result Report

Biological variation of thiopurine methyltransferase enzyme activity: when has a significant change taken place?

Remco van Egmond, Murray L Barclay, Paul KL Chin et al. · 2013 · Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

Background Thiopurine methyltransferase (TPMT) enzyme activity is measured before initiating thiopurine therapy to reduce the risk of severe drug-associated myelotoxicity in patients with low enzyme activity. TPMT activity may vary over…

View details →DOI: 10.1177/0004563212473441Cited by 7
Negative / Null Result Report

The occurrence of nonglycosylated forms of N ‐glycoprotein upon proteasome inhibition does not confirm cytosolic deglycosylation

Chengcheng Huang, Tadashi Suzuki · 2020 · FEBS Letters

N‐ Glycosylated substrates that undergo ER‐associated degradation (ERAD) are often deglycosylated by the cytosolic peptide: N ‐glycanase (Ngly1) during their proteasomal degradation in the cytosol. Consequently, the presence of non‐ or…

View details →DOI: 10.1002/1873-3468.13734Cited by 7
Negative / Null Result Report

State Anxiety after Exergame Beach Volleyball Did Not Differ between the Single and Multiplayer Modes in Adult Men

Vinnycius de Oliveira, Ricardo Viana, Naiane Morais et al. · 2021 · International Journal of Environmental Research and Public Health

This study compared the exergame beach volleyball’s acute effects on state anxiety level in single vs. multiplayer mode in adult men. Sixty adult men (age: 21.98 [4.58] years, body mass: 75.40 [15.70] kg, height: 1.77 [0.09] m, and body…

View details →DOI: 10.3390/ijerph182010957Cited by 7
Negative / Null Result Report

No significant association of repeated messages with changes in health compliance in the COVID-19 pandemic: a registered report on the extended parallel process model

Jingwen Yang, Xue Wu, Kyoshiro Sasaki et al. · 2021 · PeerJ

When people are confronted with health proposals during the coronavirus disease 2019 (COVID-19) pandemic, it has been suggested that fear of COVID-19 can serve protective functions and ensure public health compliance. However, health…

View details →DOI: 10.7717/peerj.11559Cited by 7
Negative / Null Result Report

Significant Improvement of Somatic Symptom Disorder With Brief Psychoeducational Intervention by PMHNP in Primary Care

Kim K. Johnson, Carole Bennett, Haresh Rochani · 2020 · Journal of the American Psychiatric Nurses Association

Objective: Patients with somatic symptom disorders (SSD) are prevalent in primary care, urgent care, and emergency rooms and present with reduced quality of life, increased disability, and suicidality . Criteria for SSD include (1) somatic…

View details →DOI: 10.1177/1078390320960524Cited by 7
Negative / Null Result Report

Randomized trial within a trial of yellow ‘post‐it notes’ did not improve questionnaire response rates among participants in a trial of treatments for neck pain

Helen E Tilbrook, Taeko Becque, Hannah Buckley et al. · 2014 · Journal of Evaluation in Clinical Practice

Abstract Rationale Attrition is a threat to the validity of randomized trials. Few randomized studies have been conducted within randomized trials to test methods of reducing attrition. Aim To test whether using yellow post‐it notes on…

View details →DOI: 10.1111/jep.12284Cited by 7
Negative / Null Result Report

Automated broadcast of a predator call did not reduce predation pressure by Sugar Gliders on birds

Giselle Owens, Robert Heinsohn, Sam Eyles et al. · 2020 · Ecological Management & Restoration

Summary Fear may elicit behavioural and physiological responses in animals. We conducted a pilot study aiming to reduce bird nest predation in Tasmania by the introduced Sugar Glider ( Petaurus breviceps ) by broadcasting calls of…

View details →DOI: 10.1111/emr.12423Cited by 7
Negative / Null Result Report

Motor Imaginary Task Classification using Statistically Significant Time Domain and Frequency Domain EEG features

Murside Degirmenci, Yilmaz Kemal Yuce, Yalcin Isler · 2022 · Journal of Intelligent Systems with Applications

Motor Imaginary (MI) electroencephalography (EEG) signals are obtained when a subject imagines a task without essentially applying it. The accurate decoding of MI EEG signals plays an important role in the design of brain-computer…

View details →DOI: 10.54856/jiswa.202205203Cited by 7
Negative / Null Result Report

Mixture-of-Theories training: can we find new physics and anomalies better by mixing physical theories?

Sascha Caron, Roberto Ruiz de Austri, Zhongyi Zhang · 2023 · Journal of High Energy Physics

A bstract Model-independent search strategies have been increasingly proposed in recent years because on the one hand there has been no clear signal for new physics and on the other hand there is a lack of a highly probable and…

View details →DOI: 10.1007/jhep03(2023)004Cited by 7
Negative / Null Result Report

Lack of significant effect of gut microbiota on weight gain in newly emerged worker honeybee

J. Elijah Powell, Erick V.S. Motta, Joanito Liberti et al. · 2025 · Royal Society Open Science

The western honeybee, Apis mellifera, harbours a simple and distinct microbiota that has been linked to various positive outcomes for the host. Among these cited benefits is improved weight gain for bees that have been inoculated with…

View details →DOI: 10.1098/rsos.242151Cited by 7
Negative / Null Result Report

Implementation has failed, implementation studies have failed even more: Racism and the future of systemic change

Fernando Tormos‐Aponte, James E. Wright, Heath Brown · 2021 · Social Science Quarterly

Abstract Objective This article identifies the role of structural racism in policy implementation and argues that a starting point to evaluate the potential outcomes of calls for systemic change is to better situate racism in the study of…

View details →DOI: 10.1111/ssqu.13009Cited by 7
Negative / Null Result Report

Mining statistically significant substrings using the chi-square statistic

Mayank Sachan, Arnab Bhattacharya · 2012 · Proceedings of the VLDB Endowment

The problem of identification of statistically significant patterns in a sequence of data has been applied to many domains such as intrusion detection systems, financial models, web-click records, automated monitoring systems,…

View details →DOI: 10.14778/2336664.2336677Cited by 7
Negative / Null Result Report

Multi-Objective Optimization of a Multi-Cavity, Significant Wall Thickness Difference Extrusion Profile Mold Design for New Energy Vehicles

Xuda Xu, Feng Jiang, Jianxiang Li et al. · 2024 · Materials

With the rapid development of the new energy vehicle market, the demand for extruded profiles for battery trays, mainly characterized by significant wall thickness differences in multiple chambers, is increasing, posing new challenges to…

View details →DOI: 10.3390/ma17092126Cited by 7
Negative / Null Result Report

Acetabular Labral Repair and Selective Labral Debridement Show No Significant Difference in Clinical Outcomes at a Minimum 2‐Year Follow‐Up

Tiao Su, Xinle Huang, Liu Yang et al. · 2023 · Arthroscopy

Purpose To compare the outcomes of arthroscopic labral repair using looped type suture with a matched‐pair selective labral debridement with a minimum 2‐years follow‐up. Methods We identified 378 patients undergoing primary arthroscopic…

View details →DOI: 10.1016/j.arthro.2023.05.035Cited by 7
Negative / Null Result Report

Scalar Speed Control of Induction Motors with Difference Frequency

Ozcan OTKUN · 2020 · Politeknik Dergisi

Speed monitoring of electric motors has attracted the attention of many researchers from past to present. Induction Motor (IM), which is one of the electric motor types, falls behind the nominal speed in different loads. This study was…

View details →DOI: 10.2339/politeknik.474043Cited by 7
Negative / Null Result Report

Floral scent of the Mediterranean fig tree: significant inter-varietal difference but strong conservation of the signal responsible for pollinator attraction

Li Cao, Younes Hmimsa, Salama El fatehi et al. · 2023 · Scientific Reports

Abstract For thousands of years, humans have domesticated different plants by selecting for particular characters, often affecting less-known traits, including the volatile organic compounds (VOCs) emitted by these plants for defense or…

View details →DOI: 10.1038/s41598-023-32450-6Cited by 7
Negative / Null Result Report

Comparison of PD-L1 IHC 22C3 PharmDx Combined Positive Score (CPS) in Primary Versus Metastatic Nodal Squamous Cell Carcinomas of the Head and Neck: Is There a Significant Difference?

Ahmet Surucu, Tieying Hou, Matthew Kuhar et al. · 2023 · Applied Immunohistochemistry & Molecular Morphology

PD-L1 IHC 22C3 pharmDx is an FDA-approved companion test to select patients for anti-PD-L1 immunotherapy. In head and neck squamous cell carcinoma PD-L1 expression is determined using a Combined Positive Score (CPS), which evaluates…

View details →DOI: 10.1097/pai.0000000000001140Cited by 7
Negative / Null Result Report

Shoot thinning of Semillon in a hot climate did not improve yield and berry and wine quality

Roberta De Bei, Lukas Papagiannis, Sigfredo Fuentes et al. · 2020 · OENO One

Aim: Shoot thinning is a common canopy management practice used to obtain a desired shoot density and to improve canopy microclimate. Since thinning is often carried out manually, the cost can be high. In this study the effect of severe…

View details →DOI: 10.20870/oeno-one.2020.54.3.2984Cited by 7
Negative / Null Result Report

No Significant Difference Between Intramedullary and Extramedullary Button Fixation for Distal Biceps Brachii Tendon Rupture After Cyclic Loading in a Cadaver Model

Aditi Majumdar, Christina Salas, William Chavez et al. · 2021 · Arthroscopy, Sports Medicine, and Rehabilitation

Purpose To biomechanically compare intramedullary (IM) versus extramedullary (EM) distal biceps button fixation under cyclic loading conditions, which is most representative of postoperative physiologic status. Methods This controlled…

View details →DOI: 10.1016/j.asmr.2021.01.022Cited by 7
Negative / Null Result Report

Education Finance Reform and the Great Recession: Did State Policy and Fiscal Federalism Improve Education Spending, School Resources, and Student Achievement in Pennsylvania?

Matthew P. Steinberg, Rand Quinn, J. Cameron Anglum · 2020 · Journal of Education Finance

abstract: We estimate the impact of school finance reform on adequate and equitable district spending, school resources and student achievement in Pennsylvania. From the 2008-09 to the 2010-11 school years, amid the Great Recession,…

View details →DOI: 10.1353/jef.2020.a760723Cited by 6
Negative / Null Result Report

ReplicOpter: A replicate optimizer for flexible docking

Omar N. A. Demerdash, Amanda Buyan, Julie C Mitchell · 2010 · Proteins: Structure, Function, and Bioinformatics

Abstract We present a computationally efficient method for flexible refinement of docking predictions that reflects observed motions within a protein's structural class. Using structural homologs, we derive deformation models that capture…

View details →DOI: 10.1002/prot.22811Cited by 6