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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19815 results in Negative / Null Result Report · page 154 of 661

Negative / Null Result Report

Incidence and time trends of herpes zoster among patients with head and neck cancer who did and did not undergo radiotherapy: A population-based cohort study

Peng-Yi Lee, Jung-Nien Lai, Lu-Ting Chiu et al. · 2021 · PLOS ONE

Purpose This study aimed to determine the risk and time trends of herpes zoster among patients with head and neck cancer, with or without radiotherapy. Methods A total of 2160 patients with head and neck cancer were enrolled. The…

View details →DOI: 10.1371/journal.pone.0250724Cited by 6
Negative / Null Result Report

MWPoW: Multiple Winners Proof of Work Protocol, a Decentralisation Strengthened Fast-Confirm Blockchain Protocol

Yibin Xu, Yangyu Huang · 2019 · Security and Communication Networks

Blockchain mining should not be a game among power oligarchs. In this paper, we present the Multiple Winners Proof of Work Protocol (MWPoW), a mining-pool-like decentralised blockchain consensus protocol. MWPoW enables disadvantaged nodes…

View details →DOI: 10.1155/2019/3674274Cited by 6
Negative / Null Result Report

Shared miRNA landscapes of COVID-19 and neurodegeneration confirm neuroinflammation as an important overlapping feature

Sara Redenšek Trampuž, David Vogrinc, Katja Goričar et al. · 2023 · Frontiers in Molecular Neuroscience

Introduction Development and worsening of most common neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis, have been associated with COVID-19 However, the mechanisms associated with…

View details →DOI: 10.3389/fnmol.2023.1123955Cited by 6
Negative / Null Result Report

Does SLOPE outperform bridge regression?

Shuaiwen Wang, Haolei Weng, Arian Maleki · 2021 · Information and Inference: A Journal of the IMA

Abstract A recently proposed SLOPE estimator [6] has been shown to adaptively achieve the minimax $\ell _2$ estimation rate under high-dimensional sparse linear regression models [25]. Such minimax optimality holds in the regime where the…

View details →DOI: 10.1093/imaiai/iaab025Cited by 6
Negative / Null Result Report

Education Finance Reform and the Great Recession: Did State Policy and Fiscal Federalism Improve Education Spending, School Resources, and Student Achievement in Pennsylvania?

Matthew P. Steinberg, Rand Quinn, J. Cameron Anglum · 2020 · Journal of Education Finance

abstract: We estimate the impact of school finance reform on adequate and equitable district spending, school resources and student achievement in Pennsylvania. From the 2008-09 to the 2010-11 school years, amid the Great Recession,…

View details →DOI: 10.1353/jef.2020.a760723Cited by 6
Negative / Null Result Report

ReplicOpter: A replicate optimizer for flexible docking

Omar N. A. Demerdash, Amanda Buyan, Julie C Mitchell · 2010 · Proteins: Structure, Function, and Bioinformatics

Abstract We present a computationally efficient method for flexible refinement of docking predictions that reflects observed motions within a protein's structural class. Using structural homologs, we derive deformation models that capture…

View details →DOI: 10.1002/prot.22811Cited by 6
Negative / Null Result Report

Can masked synonym priming replicate masked translation priming?

Naoko Witzel · 2019 · Quarterly Journal of Experimental Psychology

This study examines whether synonyms are represented similarly to translation equivalents in the bilingual mind. In particular, this study investigated whether there is masked synonym priming such that it will simulate masked translation…

View details →DOI: 10.1177/1747021819848683Cited by 6
Negative / Null Result Report

Who did what to whom, and what did we already know?

Tania Ionin, Maria Goldshtein, Tatiana Luchkina et al. · 2021 · Linguistic Approaches to Bilingualism

Abstract This paper reports on an experimental investigation of what second language (L2) learners and heritage speakers of Russian know about the relationship between word order and information structure in Russian. The participants…

View details →DOI: 10.1075/lab.20045.ionCited by 6
Negative / Null Result Report

Did expanded access to denture services improve chewing ability in the Korean older population? Results of a regression discontinuity analysis

Nam-Hee Kim, Ichiro Kawachi · 2020 · Scientific Reports

Abstract The Korean National Health Insurance expanded the dental insurance in 2012 to cover denture services for older adults. We analyzed whether the new policy improved of chewing ability in the eligible population. We used regression…

View details →DOI: 10.1038/s41598-020-68189-7Cited by 6
Negative / Null Result Report

The significant role of educational status in PKU patients: the beneficial effect of psychological support in depression

Kostas Iakovou, Kleopatra Schulpis · 2019 · International Journal of Adolescent Medicine and Health

Abstract Introduction Classical Phenylketonuria (PKU) is a metabolic disease characterized by high phenylalanine (phe) levels in blood and brain. PKU patients are commonly treated with low phe diet supplemented with amino acid free…

View details →DOI: 10.1515/ijamh-2018-0233Cited by 6
Negative / Null Result Report

Cover crops did not improve soil health but hydroclimatology may guide decisions preventing cash crop yield loss

Debankur Sanyal, Avik Mukherjee, Amin Rahhal et al. · 2023 · Frontiers in Soil Science

Introduction Cover crop (CC) is an essential tool to improve or maintain soil health, potentially improving cash crop productivity. Several recent reports of cash crop yield reduction following cover cropping necessitated this research to…

View details →DOI: 10.3389/fsoil.2023.1111821Cited by 6
Negative / Null Result Report

Did School Meal Programs and SNAP Participation Improve Diet Quality of US Children from Low-Income Households: Evidence from NHANES 2013–2014?

Tzuan A. Chen, Lorraine R. Reitzel, Ezemenari M. Obasi et al. · 2021 · Nutrients

Nutrition assistance programs such as school meals and the Supplemental Nutrition Assistance Program (SNAP) are designed to provide a safety net for the dietary intake of children from low-income families. However, compared with eligible…

View details →DOI: 10.3390/nu13103574Cited by 6
Negative / Null Result Report

Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites

Emily E. Fay, Lindsay C. Czuba, Jennifer E. Sager et al. · 2021 · Therapeutic Drug Monitoring

Background: Bupropion (BUP) is a chiral antidepressant and smoking cessation aide with benefits and side effects correlated with parent and active metabolite concentrations. BUP is metabolized by CYP2B6, CYP2C19, and CYP3A4 to hydroxy-BUP…

View details →DOI: 10.1097/ftd.0000000000000885Cited by 6
Negative / Null Result Report

Diversity, equity and inclusion work: a difference that makes a difference … ?

Ann Armstrong · 2024 · Equality, Diversity and Inclusion: An International Journal

Purpose I examine if current diversity, equity and inclusion (DEI) initiatives can actually accomplish what they aim and claim to do. I argue that perforce they cannot, as they remain instruments of capitalist corporations and other…

View details →DOI: 10.1108/edi-10-2023-0325Cited by 6
Negative / Null Result Report

No significant difference between Australian heat wave impacts of Modoki and eastern Pacific El Niño

Tammas F. Loughran, Sarah E. Perkins‐Kirkpatrick, Lisa V. Alexander et al. · 2017 · Geophysical Research Letters

Abstract The influence of two El Niño types on the frequency of summer heat wave days in Australia is investigated using both observations and an atmospheric climate model. The two basic spatial variants of El Niño are the traditional…

View details →DOI: 10.1002/2017gl073231Cited by 6
Negative / Null Result Report

The Continuous Fragility Index of Statistically Significant Findings in Studies Based on High Levels of Evidence Comparing Interventions for Femoroacetabular Impingement Syndrome

Juan Bernardo Villarreal-Espinosa, Zeeshan A. Khan, Kyleen Jan et al. · 2025 · The American Journal of Sports Medicine

Background: Critical analysis of studies with high level of evidence has relied on the significance set by the reported P values. However, this strategy steers readers toward categorical interpretation of the data; therefore, a more…

View details →DOI: 10.1177/03635465241283967Cited by 6
Negative / Null Result Report

Extracting statistically significant eddy signals from large Lagrangian datasets using wavelet ridge analysis, with application to the Gulf of Mexico

Jonathan M. Lilly, Paula Pérez-Brunius · 2021 · Nonlinear Processes in Geophysics

Abstract. A method for objectively extracting the displacement signals associated with coherent eddies from Lagrangian trajectories is presented, refined, and applied to a large dataset of 3770 surface drifters from the Gulf of Mexico. The…

View details →DOI: 10.5194/npg-28-181-2021Cited by 6
Negative / Null Result Report

A Meta-Epidemiological Study of Positive Results in Clinical Nutrition Research: The Good, the Bad and the Ugly of Statistically Significant Findings

Konstantinos Gkiouras, Maria-Eleftheria Choleva, Aikaterini Verrou et al. · 2022 · Nutrients

Positive (statistically significant) findings are easily produced in nutrition research when specific aspects of the research design and analysis are not accounted for. To address this issue, recently, a pledge was made to reform nutrition…

View details →DOI: 10.3390/nu14235164Cited by 6
Negative / Null Result Report

No statistically significant difference in long term scarring outcomes of pediatric burns patients treated surgically vs. those treated conservatively

Riyam Mistry, Fadi Issa · 2022 · Frontiers in Surgery

Introduction Paediatric burns are a common clinical presentation. The long-term scar outcomes in paediatric burns patients are relatively unknown as most are discharged after 6 weeks follow up, apart from the small number that are followed…

View details →DOI: 10.3389/fsurg.2022.727983Cited by 6
Negative / Null Result Report

Photobiomodulation therapy in dogs undergoing TPLO after cranial cruciate ligament rupture shows promise but no statistically significant difference in a randomized trial

Oscar A. Chavez, Walter Renberg, Natalia Cernicchiaro · 2024 · American Journal of Veterinary Research

Abstract OBJECTIVE Effect of photobiomodulation therapy (PBMT) in patients with CCLR after TPLO surgery by measuring C-reactive protein (CRP), percentage weight bearing, lameness using a short form of a composite measure pain scale,…

View details →DOI: 10.2460/ajvr.23.06.0138Cited by 6
Negative / Null Result Report

Root-knot nematodes demonstrate temporal variation in host penetration

Shova Mishra, Peter DiGennaro · 2020 · Journal of Nematology

Abstract Root-knot nematodes (RKN; Meloidogyne spp.) are obligate plant parasites that require constant communication with their host to establish and maintain specialized feeding cells. The intimacy of this interaction likely requires…

View details →DOI: 10.21307/jofnem-2020-037Cited by 6
Negative / Null Result Report

A school-based supplementary food programme in rural Kenya did not reduce children's intake at home

Constance A Gewa, Suzanne P Murphy, Robert E Weiss et al. · 2012 · Public Health Nutrition

Abstract Objective To examine changes in energy intake along with markers of dietary quality (animal-source energy and protein intakes) among household members in the presence of supplementary school feeding in rural Kenya. Design A…

View details →DOI: 10.1017/s1368980012003266Cited by 6