Negative / Null Result ReportOpen accessMedicine
Adrian K. Davison, Ashma Krishan, Robert P New et al. · 2024 · Lara D. Veeken
OBJECTIVES: To test the hypothesis that photographs (in addition to self-reported data) can be collected daily by patients with SSc using a smartphone app designed specifically for digital lesions, and could provide an objective outcome measure for use in clinical trials. METHODS: An app was developed to collect images and patient-reported outcome measures including Pain score and the Hand Disability in Systemic Sclerosis-Digital Ulcers (HDISS-DU) questionnaire. Participants photographed their lesion(s) each day for 30 days and uploaded images to a secure repository. Lesions were analysed both
View details →DOI: 10.1093/rheumatology/keae371Cited by 10 Negative / Null Result Report
Ian I. Courter, Tom Chance, Ryan Gerstenberger et al. · 2022 · Canadian Journal of Fisheries and Aquatic Sciences
For over 150 years, hatchery-origin anadromous salmon and trout have been reared and released throughout the Pacific Northwest to mitigate for lost habitat and sustain harvest opportunity. Some studies demonstrate that introgression of…
View details →DOI: 10.1139/cjfas-2021-0351Cited by 10 Negative / Null Result Report
Wändi Bruine de Bruin, Laurel Kruke, Gale M. Sinatra et al. · 2024 · Climatic Change
Abstract The terms “global warming,” “climate crisis,” “climate emergency,” and “climate justice” each draw attention to different aspects of climate change. Psychological theories of attitude formation suggest that people’s attitudes can…
View details →DOI: 10.1007/s10584-024-03786-3Cited by 10 Negative / Null Result Report
Annie McCluskey, Sally Bennett, Tammy Hoffmann et al. · 2010 · Health Information & Libraries Journal
Abstract Background: Research is essential for evidence‐based practice yet many health professionals do not have enough time to find research. Studies relevant to occupational therapists can be particularly difficult to find. Most search…
View details →DOI: 10.1111/j.1471-1842.2010.00877.xCited by 10 Negative / Null Result ReportOpen accessMedicine
Qiang Tang, Yanwei Liu, Yingfeng Fu et al. · 2021 · Scientific Reports
The 2019 Coronavirus Disease (COVID-19) has become an unprecedented public crisis. We retrospectively investigated the clinical data of 197 COVID-19 patients and identified 88 patients as disease aggravation cases. Compared with patients without disease aggravation, the aggravation cases had more comorbidities, including hypertension (25.9%) and diabetes (20.8%), and presented with dyspnoea (23.4%), neutrophilia (31.5%), and lymphocytopenia (46.7%). These patients were more prone to develop organ damage in liver, kidney, and heart (P < 0.05). A multivariable regression analysis showed that adv
View details →DOI: 10.1038/s41598-021-87413-6Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Zhongwei Liu, Shuang Shi, Haitao Zhu et al. · 2018 · International Heart Journal
The phenotype shifting of vascular smooth muscle cells (VSMCs) was indicated to play a role during the initial stage of atherosclerotic plaque formation by facilitating extracellular matrix deposition. This study was aimed at investigating…
View details →DOI: 10.1536/ihj.17-625Cited by 10 Negative / Null Result ReportOpen accessMedicine
Lien Anh Ha Do, Zheng Quan Toh, Paul Vincent Licciardi et al. · 2021 · The Lancet Global Health
Measles virus and respiratory syncytial virus (RSV) are two important global health pathogens causing substantial morbidity and mortality worldwide. The current measles vaccination schedule has the first dose given at 9-12 months of age…
View details →DOI: 10.1016/s2214-109x(21)00464-2Cited by 10 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Michal Mego, Barbora Judita Kasperová, Jozef Chovanec et al. · 2024 · Frontiers in Oncology
Background: Probiotics could decrease irinotecan-induced diarrhea due to the reduction of intestinal beta-d-glucuronidase activity. This study included a combined analysis of two clinical trials aimed to determine the effectiveness of the probiotics in the prophylaxis of irinotecan-induced diarrhea in metastatic colorectal cancer (CRC) patients. Methods: This combined analysis included 46 patients with CRC enrolled in the Probio-SK-003 (NCT01410955) and 233 patients from Probio-SK-005 (NCT02819960) starting a new line of irinotecan-based therapy with identical eligibility criteria. Patients we
View details →DOI: 10.3389/fonc.2024.1438657Cited by 10 Negative / Null Result ReportOpen accessMedicine
Ciara Conduit, Ian D. Davis, Jeffrey C. Goh et al. · 2023 · British Journal of Urology
OBJECTIVE: To evaluate the efficacy of sequential treatment with ipilimumab and nivolumab following progression on nivolumab monotherapy in individuals with advanced, non-clear-cell renal cell carcinoma (nccRCC). MATERIALS AND METHODS:…
View details →DOI: 10.1111/bju.16190Cited by 10 Negative / Null Result ReportOpen accessMedicine
Silvia Park, Emma Langley, Jong‐Mu Sun et al. · 2015 · Oncotarget
// Silvia Park 1, * , Emma Langley 2, * , Jong-Mu Sun 1 , Steve Lockton 2 , Jin Seok Ahn 1 , Anjali Jain 2 , Keunchil Park 1 , Sharat Singh 2 , Phillip Kim 2 , Myung-Ju Ahn 1 1 Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 2 Prometheus Laboratories Inc, A Nestlé Health Science Company, Department of Research and Development, San Diego, CA, USA * These authors have contributed equally to this work Correspondence to: Myung-Ju Ahn, e-mail: silkahn@skku.edu Phillip Kim, e-mail: pkim@prometheuslabs.co
View details →DOI: 10.18632/oncotarget.5131Cited by 10 Negative / Null Result Report
Christopher A. Tait, Abtin Parnia, Nishan Zewge-Abubaker et al. · 2020 · BMC Public Health
Abstract Background Child mortality has been reduced by more than 50 % over the past 30 years. A range of secular economic and social developments have been considered to explain this phenomenon. In this paper, we examine the association…
View details →DOI: 10.1186/s12889-020-08720-7Cited by 10 Negative / Null Result ReportOpen accessDecision Sciences
John Protzko, Jonathan W. Schooler · 2020 · PeerJ
What explanation is there when teams of researchers are unable to successfully replicate already established ‘canonical’ findings? One suggestion that has been put forward, but left largely untested, is that those researchers who fail to replicate prior studies are of low ‘expertise and diligence’ and lack the skill necessary to successfully replicate the conditions of the original experiment. Here we examine the replication success of 100 scientists of differing ‘expertise and diligence’ who attempted to replicate five different studies. Using a bibliometric tool ( h -index) as our indicator
View details →DOI: 10.7717/peerj.8014Cited by 10 Negative / Null Result ReportOpen accessPsychology
Ioana M. Latu, Sean Duffy, Vaani Pardal et al. · 2017 · Comprehensive Results in Social Psychology
In the current study, we sought to replicate the finding that adopting an open/expansive body posture increases subjective feelings of power, while also investigating how these body postures influence the processing of persuasive messages.…
View details →DOI: 10.1080/23743603.2017.1327178Cited by 10 Negative / Null Result ReportOpen accessHealth Professions
Nasser Lubega, Abigail Anderson, Nicole Nelson · 2023 · PLoS ONE
High rates of irreproducibility and of poor mental health in graduate students have been reported in the biomedical sciences in the past ten years, but to date, little research has investigated whether these two trends interact. In this study, we ask whether the experience of failing to replicate an expected finding impacts graduate students' mental health. Using an online survey paired with semi-structured qualitative interviews, we examined how often biomedical science doctoral students at a large American public university experienced events that could be interpreted as failures to replicat
View details →DOI: 10.1371/journal.pone.0293584Cited by 10 Negative / Null Result ReportOpen accessHealth Professions
Ann‐Marie Towers, Stacey Rand, Stephen Allan et al. · 2025 · BMJ Open
OBJECTIVES: To assess the feasibility of capturing older care home residents' quality of life (QoL) in digital social care records and the construct validity (hypothesis testing) and internal consistency (Cronbach's alpha) of four QoL measures. DESIGN: doption) study, a mixed-methods pilot of a prototype minimum dataset (MDS). SETTING: Care homes (with or without nursing) registered to provide care for older adults (>65 years) and/or those living with dementia. All homes used a digital record system from one of two suppliers. PARTICIPANTS: Data were extracted from 748 residents. All permanent
View details →DOI: 10.1136/bmjopen-2024-090684Cited by 10 Negative / Null Result ReportOpen accessSocial Sciences
Giovanna M. Invernizzi, Ahmed Ezzeldin Mohamed · 2022 · Journal of Experimental Political Science
Abstract How does exposure to conspiracy theories affects voters’ political attitudes? Using an online experiment among US subjects, we show that exposure to conspiracy theories decreases voters’ trust in the domestic informational…
View details →DOI: 10.1017/xps.2022.11Cited by 10 Negative / Null Result ReportEconomics, Econometrics and Finance
Goodness C. Aye, Olorato Gadinabokao, Rangan Gupta · 2016 · Energy Sources Part B Economics Planning and Policy
Causality testing procedures in the frequency domain and the time domain are employed to analyses the relationship between oil prices and interest rate in South Africa, covering the time period January 1936–November 2013 . Results show…
View details →DOI: 10.1080/15567249.2014.966927Cited by 10 Negative / Null Result ReportOpen accessComputer Science
Fabrice Djatsa · 2019 · Journal of Information Security
As the economy increases its dependence on the internet to increase efficiency and productivity in all aspects of society, close attention has been directed to solve the challenges related to internet security. Despite the large amount of…
View details →DOI: 10.4236/jis.2020.111002Cited by 10 Negative / Null Result ReportOpen accessPsychology
R. Constance Wiener, Alcinda Trickett Shockey, D. Leann Long · 2014 · Journal of Dental Education
Geriatric education is an important component of the dental hygiene curriculum because, in it, students acquire skills and attitudes to help provide quality care to older adults. The purpose of this study was to determine if off-site…
View details →DOI: 10.1002/j.0022-0337.2014.78.12.tb05840.xCited by 10 Negative / Null Result ReportOpen accessHealth Professions
Paul Kwame Essandoh, Frederick Ato Armah, Ernest K. A. Afrifa et al. · 2011 · Environment and Natural Resources Research
Environmental noise pollution generated from industrial and transport activities in Ghana have received considerable attention from regulators and policy makers unlike rising noise levels in residential settings. This study measured ambient noise levels in four halls of residence in the University of Cape Coast (UCC), Ghana to ascertain compliance with permissible limits. Questionnaires were also used to evaluate the possible non-auditory noise effects. The results indicate that the same sex halls (Adeyhe and Casford) were within the day and night permissible noise limit of the Ghana Environme
View details →DOI: 10.5539/enrr.v1n1p181Cited by 10 Negative / Null Result ReportOpen accessPsychology
Savannah Kelly · 2017 · Evidence Based Library and Information Practice
Abstract Objective – The purpose of this quantitative study was to measure the impact of providing research struggle videos on first-year students’ research self-efficacy. The three-part video series explicated and briefly addressed common…
View details →DOI: 10.18438/b8qq28Cited by 10 Negative / Null Result ReportOpen accessMedicine
Muhammad Junaid Tahir, Komal Tehzeeb, Farah Javaid et al. · 2023
Background: Parkinson's disease, is a degenerative neurological disorder, may have an adverse effect on movement, balance, and coordination. Physical therapy, a frequent Parkinson's disease treatment, tries to improve the patient's…
View details →DOI: 10.53555/jptcp.v30i19.3685Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Jeanne M. McCaffery, George D. Papandonatos, Lucy F. Faulconbridge et al. · 2015 · Psychosomatic Medicine
OBJECTIVES: Numerous studies have found elevated depressive symptoms among individuals with Type 2 diabetes, yet the mechanisms remain unclear. We examined whether genetic loci previously associated with depressive symptoms predict…
View details →DOI: 10.1097/psy.0000000000000242Cited by 10 Negative / Null Result ReportOpen accessNeuroscience
Christopher J. Wertz, Faith M Hanlon, Nicholas A. Shaff et al. · 2018 · Schizophrenia Bulletin
Inhibitory failure represents a core dysfunction in patients with schizophrenia (SP), which has predominantly been tested in the literature using reactive (ie, altering behavior after a stimulus) rather than proactive (ie, purposefully…
View details →DOI: 10.1093/schbul/sby086Cited by 10 Negative / Null Result ReportMedicine
Leon Veryard, Emma Jones, Gary Weaving et al. · 2013 · Current Alzheimer Research
Increased concentrations of pro-inflammatory blood cytokines and plasma homocysteine (Hcy) are frequently reported in Alzheimer's disease (AD). Hcy appears to have immunomodulating and pro-inflammatory activities. Further, emerging…
View details →DOI: 10.2174/1567205011310020007Cited by 10 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Shaoyuan Tan, Weixin Wu, Xinna Ge et al. · 2023 · One Health Advances
Porcine reproductive and respiratory syndrome virus (PRRSV) is an economically important pathogen for the global pork industry. Although modified live virus (MLV) vaccines are commonly used for PRRSV prevention and control, they still carry a risk of infecting the host and replicating in target cells, thereby increasing the likehood of virus recombination and reversion to virulence. In this study, we inserted the target sequence of miR-142 into the nsp2 hypervariable region of PRRSV to inhibit viral replication in its host cells of pigs, with the aim of achieving virus attenuation. The chimeri
View details →DOI: 10.1186/s44280-023-00002-2Cited by 10 Negative / Null Result ReportPsychology
Jeannette Fuller, James Tapp, Simon Draycott · 2019 · Criminal Behaviour and Mental Health
BACKGROUND: Motivation and readiness to change are important drives for forensic patients accessing interventions. It is thought that guilt and shame influence these drives, but to date, their relationship has not been empirically tested.…
View details →DOI: 10.1002/cbm.2105Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Gabriele Meyer, Jeffrey R. Leipprandt, Jianwei Xie et al. · 2012 · Endocrinology
Mammary organoids from adult mice produce tubules, analogous to mammary ducts in vivo, in response to hepatocyte growth factor (HGF) when cultured in collagen gels. The combination of HGF plus progestin (R5020) causes reduced tubule number…
View details →DOI: 10.1210/en.2012-1518Cited by 10 Negative / Null Result ReportOpen accessNeuroscience
Nicholas Murphy, Alison Killen, Rajnish Kumar Gupta et al. · 2021 · Frontiers in Neurology
Visual hallucinations (VH) are a common symptom of Parkinson's disease with dementia (PDD), affecting up to 65% of cases. Integrative models of their etiology posit that a decline in executive control of the visuo-perceptual system is a primary mechanism of VH generation. The role of bottom-up processing in the manifestation of VH in this condition is still not clear although visual evoked potential (VEP) differences have been associated with VH at an earlier stage of PD. Here we compared the amplitude and latency pattern reversal VEPs in healthy controls ( n = 21) and PDD patients ( n = 34) w
View details →DOI: 10.3389/fneur.2020.579113Cited by 10 Negative / Null Result ReportOpen accessMedicine
Marie Lefebvre, Michael P. Hengartner, Enrico Tronci et al. · 2022 · Physiology & Behavior
BACKGROUND: As eating behavior changes in relation to the menstrual cycle and weight changes with menopausal transition, ovarian hormones appear to be involved in regulating eating behavior. However, observations are contradictory and are difficult to compare, due to methodological problems related to nutritional epidemiology. To better understand the relationship between ovarian steroid hormones and eating behavior, our study evaluates women's responses to visual food cues at different points in the menstrual cycle with their specific serum estrogen/progesterone levels and women's responses i
View details →DOI: 10.1016/j.physbeh.2022.113943Cited by 10 