Negative / Null Result ReportOpen accessNeuroscience
Clara E. James · 2012 · Frontiers in Psychology
A commentary on Musical expertise and statistical learning of musical and linguistic structures by Schön, D., and François, C. (2011). Front. Psychology 2:167. doi: 10.3389/ fpsyg.2011.00167 Both language and music consist of discrete elements organized in embedded hierarchical structures. Schön and François nicely expose in this review that musical expertise facilitates learning of both linguistic and musical structures. At the behavioral level, the musicians did not outperform the nonmusicians. However, ERP analyses showed that acquisition of boundary perception (segmentation) between units
View details →DOI: 10.3389/fpsyg.2012.00052Cited by 12 Negative / Null Result ReportOpen accessNeuroscience
Alice Mason, Casimir J. H. Ludwig, Simon Farrell · 2016 · Quarterly Journal of Experimental Psychology
Reward is thought to enhance episodic memory formation via dopaminergic consolidation. Bunzeck, Dayan, Dolan, and Duzel [(2010). A common mechanism for adaptive scaling of reward and novelty. Human Brain Mapping, 31, 1380-1394] provided functional magnetic resonance imaging (fMRI) and behavioural evidence that reward and episodic memory systems are sensitive to the contextual value of a reward-whether it is relatively higher or lower-as opposed to absolute value or prediction error. We carried out a direct replication of their behavioural study and did not replicate their finding that memory p
View details →DOI: 10.1080/17470218.2016.1233439Cited by 12 Negative / Null Result ReportOpen accessMedicine
Lígia Ramos dos Santos, Jucimara Ferreira Figueiredo Almeida, Lúcia Helena Sagrillo Pimassoni et al. · 2019 · Genetics and Molecular Biology
Genome-wide associations studies (GWAS) are detecting new variants associated with late-onset of Alzheimer's disease (LOAD), a multifactorial neurodegenerative disorder. The variants rs744373 BIN1, rs11136000 CLU and rs3764650 ABCA7 uncovered by GWAS led to different AD pathways, such as metabolism, trafficking and endocytosis of lipids and inflammation. However, most of the association studies did not replicate these variants with significance. This could be due to a small power effect evident when these variants are tested independently with LOAD. Therefore, we aimed to investigate whether t
View details →DOI: 10.1590/1678-4685-gmb-2018-0320Cited by 12 Negative / Null Result ReportOpen accessNeuroscience
Stefan Wiens, Erik van Berlekom, Malina Szychowska et al. · 2019 · Frontiers in Psychology
The mismatch negativity (MMN) has been of particular interest in auditory perception because of its sensitivity to auditory change. It is typically measured in an oddball task and is computed as the difference of deviant minus standard tones. Previous studies suggest that the oddball MMN can be reduced by crossmodal attention to a concurrent, difficult visual task. However, more recent studies did not replicate this effect. Because previous findings seem to be biased, we preregistered the present study and used Bayesian hypothesis testing to measure the strength of evidence for or against an e
View details →DOI: 10.3389/fpsyg.2019.01970Cited by 12 Negative / Null Result ReportOpen accessSocial Sciences
Laura Macchi, Francesco Poli, Laura Caravona et al. · 2019 · Europe’s Journal of Psychology
The previous research attempts to reduce the influence of the belief bias on deductive thinking have often been unsuccessful and, when they succeeded, they failed to replicate. In this paper, we propose a new way to see an old problem. Instead of considering the analytical abilities of the respondent, we focus on the communicative characteristics of the experimental task. By changing the pragmatics into play through a subtle manipulation of the instruction of the syllogism problem, we obtained a strong improvement in the accuracy of the performance in both untrained and trained in logic respon
View details →DOI: 10.5964/ejop.v15i3.1794Cited by 12 Negative / Null Result ReportOpen accessImmunology and Microbiology
Marcello Candelli, Marta Sacco Fernandez, Gloria Rozzi et al. · 2025 · Diagnostics
Background and Objectives: Despite major advances in medical science and critical care, sepsis remains a leading cause of morbidity and mortality worldwide: it arises from dysregulated host response to infections and may culminate in organ dysfunction. A hallmark of its pathogenesis is the cytokine storm, in which interleukins (ILs) serve as central mediators of both protective and deleterious immune responses. This review summarizes the current knowledge on the role of ILs in sepsis, emphasizing their potential as biomarkers and therapeutic targets. Material and Methods: We analyzed recent cl
View details →DOI: 10.3390/diagnostics15222927Cited by 11 Negative / Null Result ReportOpen accessMedicine
Martin G Schultz, Petr Otahal, Philip Roberts-Thomson et al. · 2025 · European Heart Journal
BACKGROUND AND AIMS: A hypertensive response to exercise is independently associated with cardiovascular disease (CVD), but clinical interpretation may be confounded by aerobic capacity (fitness). The aim of this study was to determine the relationship between exercise blood pressure (BP) relative to fitness and CVD events. METHODS: Clinical exercise test records were analysed from 12 743 people (aged 53 ± 13 years, 60% male) who completed a standard exercise stress test (Bruce treadmill protocol, stages 1-4) at six Australian hospitals. Records were linked to administrative datasets (hospital
View details →DOI: 10.1093/eurheartj/ehaf1082Cited by 11 Negative / Null Result ReportOpen accessNeuroscience
Eric A. Finkel, Yi-Ting Chang, Rajan Dasgupta et al. · 2024 · Cell Reports
The brain receives constant tactile input, but only a subset guides ongoing behavior. Actions associated with tactile stimuli thus endow them with behavioral relevance. It remains unclear how the relevance of tactile stimuli affects…
View details →DOI: 10.1016/j.celrep.2024.113991Cited by 11 Negative / Null Result ReportOpen accessNeuroscience
Astrid Feiten, Kilian Dahm, Kai Schlepckow et al. · 2026 · Nature Communications
Triggering receptor expressed on myeloid cells 2 (TREM2) is a central regulator of microglial activity and loss-of-function coding variants are major risk factors for late onset Alzheimer's disease (LOAD). To better understand the molecular and functional changes associated with TREM2 signalling in microglia, we generated a TREM2 reporter mouse. In APP transgenic animals, bulk RNA-sequencing of isolated microglia sorted based on reporter expression highlighted TREM2 level-related changes in major immunometabolic pathways, and enrichment of genes in oxidative phosphorylation and cholesterol met
View details →DOI: 10.1038/s41467-026-68706-8Cited by 11 Negative / Null Result ReportOpen accessMedicine
Fiona McPhee, Joseph Ueland, Vincent Vellucci et al. · 2019 · Antimicrobial Agents and Chemotherapy
[tested DAAs] of >5,000 nM) and were detected in evaluated GT-6b and -6f sequences. NS5A-L28A-R30A, observed in GT-6r, did not replicate. In conclusion, HCV GT-6b, GT-6f, and GT-6r sequences harbored highly resistant RASs to all evaluated…
View details →DOI: 10.1128/aac.02205-18Cited by 11 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Martin Olsson, Joacim Tå̊g · 2025 · The Journal of Finance
ABSTRACT Privatization of state‐owned enterprises is on the agenda across the globe. Using Swedish data covering two decades, we show that productivity gains and headcount reductions are associated with economic costs for incumbent…
View details →DOI: 10.1111/jofi.13462Cited by 11 Negative / Null Result ReportOpen accessSocial Sciences
Junhua Dang, Zeynep E. Ekim, Sarah Ohlsson et al. · 2020 · BMC Psychology
BACKGROUND: Previous studies showed that anger, rather than sadness, created automatic intergroup bias in a minimal group context. METHODS: The current research reports a single study (N = 99) aiming to replicate this finding and further to test whether the intergroup bias manifests as ingroup favoritism, outgroup derogation, or both. RESULTS: Our results failed to replicate the effect of anger on automatic bias. Intriguingly, participants across all emotion conditions exhibited high level of ingroup favoritism, but there was little evidence of outgroup derogation. CONCLUSION: These results su
View details →DOI: 10.1186/s40359-020-00414-4Cited by 11 Negative / Null Result ReportMedicine
Han Sang Kim, Jung Yong Hong, Jaekyung Cheon et al. · 2020 · Journal of Clinical Oncology
4584 Background: Previously, two phase III clinical trials of immune checkpoint inhibitors (ICI) failed to meet their primary endpoints, leading to doubts regarding the clinical activity of ICI monotherapy in patients with aHCC. Here, we…
View details →DOI: 10.1200/jco.2020.38.15_suppl.4584Cited by 11 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Fanzhuo Xu, Yu Xie, Weiwei Yu et al. · 2026 · Frontiers in Microbiology
Multidrug resistance in Gram-negative bacteria has become a significant global public health challenge, threatening human health and clinical treatment outcomes. The unique outer membrane structure of these pathogens greatly limits antibiotic penetration, serving as the core mechanism of resistance. This paper systematically analyses antimicrobial strategies targeting the outer membrane of Gram-negative bacteria, mainly including: (1) directly disrupting the outer membrane structure and enhancing drug permeability; (2) inhibiting the biosynthesis or transport pathways of key outer membrane com
View details →DOI: 10.3389/fmicb.2026.1734749Cited by 11 Negative / Null Result ReportMedicine
Mélissa De Regge, Koenraad G. Monsieurs, K. Vandewoude et al. · 2012 · PubMed
Automated external defibrillators (AEDs) have shown to improve survival after cardiopulmonary arrest (CPA) in many, but not all clinical settings. A recent study reported that the use of AEDs in-hospital did not improve survival. The…
View details →DOI: 10.2143/acb.67.4.2062666Cited by 11 Negative / Null Result ReportOpen accessMedicine
Xinyi Chen, Mu Yang, Yongbiao Huang et al. · 2025 · Therapeutic Advances in Medical Oncology
Abscopal immunity—the regression of distant, non-irradiated lesions after localized radiotherapy (RT)—signals conversion of focal DNA damage into systemic antitumor immunity. This review advances a unifying three-stage…
View details →DOI: 10.1177/17588359251387534Cited by 11 Negative / Null Result ReportOpen accessSocial Sciences
Amy Nivette, Christof Nägel, Emily Gilbert · 2023 · Police Practice and Research
High-profile incidents of police misconduct can have serious consequences for public trust in the police. A recent study in the British Journal of Political Science found that Eric Garner’s death in NYC lead to more negative attitudes towards the police in London among Black residents compared to White and Asian residents. The current study aimed to replicate this transnational effect by assessing the impact of George Floyd’s death on Londoners’ perceptions of police. Using the same data and methodological approach, we did not replicate the immediate effect on Black Londoners’ attitudes. We di
View details →DOI: 10.1080/15614263.2023.2185241Cited by 11 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Ryan H. Boe, Catherine G. Triandafillou, Rossana Lazcano et al. · 2026 · Genome biology
Abstract Resistance to cancer therapy is driven by both cell-intrinsic and microenvironmental factors. We use spatial transcriptomics and single-cell RNA sequencing to uncover distinct resistance programs in melanoma cells shaped by intrinsic cellular states and the tumor microenvironment. Consensus non-negative matrix factorization reveals shared intrinsic resistance programs across cell lines. In patient samples, these resistance programs coexist within individual tumors and associate with diverse immune signatures. Single-cell resolution spatial transcriptomics in xenograft models reveals b
View details →DOI: 10.1186/s13059-026-04112-zCited by 11 Negative / Null Result ReportOpen accessMathematics
Yong Li, Henry Sun, Zuoli Zhang · 2025 · Pharmaceutics
Background: Physiologically based pharmacokinetic (PBPK) modeling is a mathematical approach that integrates human physiological parameters with drug-specific characteristics (including both active pharmaceutical ingredients and excipients), and it has emerged as one of the core technologies for optimizing the efficiency and reliability of drug development. Methods: This study synthesizes applications of PBPK models in FDA-approved drugs (2020–2024), systematically analyzing model utilization frequency, indication distribution, application domains and choice of modeling platforms, to reveal th
View details →DOI: 10.3390/pharmaceutics17111413Cited by 11 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Gabriele Cristelli, Francesco Lissoni · 2026 · Journal of the European Economic Association
Abstract We study the innovation effects of the Agreement on the Free Movement of Persons, signed by Switzerland and the European Union in 1999. We exploit a quasi-experimental setting created by Switzerland’s implementation of the treaty, which initially eased entry restrictions only for commuters from neighboring countries, thereby inducing a large inflow of “cross-border inventors” in regions close to the border. We find that the treaty increased patenting in such regions relative to comparable ones farther away from the border. We find no evidence indicating the displacement of native inve
View details →DOI: 10.1093/jeea/jvag003Cited by 11 Negative / Null Result ReportOpen accessPhysics and Astronomy
Hanjie Tan, Xiaoran Yan, Jian‐Yang Li · 2026 · The Astrophysical Journal Letters
Abstract 3I/ATLAS is an interstellar object whose activity provides critical insights into its composition and origin. However, due to its orbital geometry, the object is too close to the Sun near perihelion to be observed from the ground, and space-based measurements are therefore required. Here we characterize the water production rate of 3I/ATLAS using Solar and Heliospheric Observatory/SWAN Ly α observations from 2025 November to December (heliocentric distances 1.4–2.2 au) with 3D Monte Carlo modeling. We report a peak postperihelion water production rate of Q H 2 O ≈ 4 × 1 0 28 molecules
View details →DOI: 10.3847/2041-8213/ae3c97Cited by 11 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Andrei Teodor Matei, Anita Ioana Vișan · 2025 · Antibiotics
The growing ineffectiveness of common antibiotics against multidrug-resistant pathogens has made antimicrobial resistance (AMR) a serious global health concern. This review emphasizes that natural antibiotics from animals, bacteria, fungi, and plants are worthy alternatives for combating this crisis. Evolutionary pressure has shaped these molecules, leading to antibiotic-resistant bacteria that can withstand single-target synthetic drugs but are vulnerable to multiple attack pathways (e.g., cell wall disruption, protein synthesis inhibition, biofilm interference) from natural compounds. Natura
View details →DOI: 10.3390/antibiotics14100981Cited by 11 Negative / Null Result ReportOpen accessEngineering
Zhaowei Yang, Wenqi Liu, Miwei Li et al. · 2025 · Energy Engineering
Accurate short-term wind power forecast technique plays a crucial role in maintaining the safety and economic efficiency of smart grids. Although numerous studies have employed various methods to forecast wind power, there re... | Find, read and cite all the research you need on Tech Science Press
View details →DOI: 10.32604/ee.2025.059515Cited by 11 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Bile Abdisalan Nor, Yusniliyana Yusof · 2025 · Discover Sustainability
Abstract Somalia’s economy has faced persistent instability due to shocks from COVID-19, climate-related disasters, and conflict, resulting in stagnant GDP growth (averaging 2% from 2019 to 2023) and declining real GDP per capita (− 0.8% annually). Despite government expenditure rising to 9% of GDP in 2021, its efficiency in driving growth remains uncertain, raising critical questions about fiscal policy effectiveness in fragile states. We aim to investigate the relationship between government expenditure and GDP growth in Somalia from 1991 to 2021 using the ARDL estimation technique. The resu
View details →DOI: 10.1007/s43621-025-01471-8Cited by 11 Negative / Null Result ReportOpen accessPsychology
Sarah Shi Hui Wong, Sophia Xuefei Qiu · 2026 · Educational Psychology Review
Abstract Generative artificial intelligence (AI) tools such as ChatGPT can boost creative performance, but do these boosts translate into learning gains? This study examined whether the benefits of ChatGPT for creativity persist even when its assistance is removed, and how people can effectively use ChatGPT to enhance their learning and independent creativity. University students ( N = 196) solved a creative product improvement task either independently (human-only group) or using ChatGPT freely (general-AI group) or using ChatGPT in a guided way (regulated-AI group). Specifically, the regulat
View details →DOI: 10.1007/s10648-026-10118-7Cited by 11 Negative / Null Result ReportOpen accessEngineering
Yiyin Nie, Shujie Jiao, Xing Yang et al. · 2026 · Light Science & Applications
Abstract The rapid advancement of artificial intelligence has propelled the development of β-Ga 2 O 3 photo-synapses for solar-blind ultraviolet neuromorphic machine vision systems. However, existing β-Ga 2 O 3 photo-synapses not only exhibit reduced stability but also display high weight update nonlinearity. Herein, we propose a novel strategy to construct β-Ga 2 O 3 photo-synapses with low weight update nonlinearity based on self-trapped holes, aiming to achieve multi-level in-sensor computing tasks. Theoretical and experimental investigations revealed that the interaction between the larger
View details →DOI: 10.1038/s41377-026-02298-2Cited by 11 Negative / Null Result ReportOpen accessMedicine
Edward Tyrrell, Suniljeet Sandhu, Kathryn Berry et al. · 2025 · JMIR Formative Research
Background: There is a need to increase health care professional training capacity to meet global needs by 2030. Effective communication is essential for delivering safe and effective patient care. Artificial intelligence (AI) technologies may provide a solution. However, evidence for high-fidelity virtual patient simulators using unrestricted 2-way verbal conversation for communication skills training is lacking. Objective: This study aims to compare a fully automated AI-driven voice recognition-based virtual patient simulator with traditional actor-based consultation skills simulated trainin
View details →DOI: 10.2196/71667Cited by 11 Negative / Null Result ReportOpen accessSocial Sciences
Roddy Theobald, Zeyu Xu, Allison F. Gilmour et al. · 2025 · Educational Evaluation and Policy Analysis
We study the impact of a bonus policy in Hawai‘i Public Schools that raised the salaries of all special education teachers by $10,000. We estimate that this policy reduced the proportion of vacant special education teaching positions…
View details →DOI: 10.3102/01623737241310905Cited by 11 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
He Chen, Shaochen Yu, Mengjie Zhang et al. · 2026 · Frontiers in Immunology
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder resulting from a combination of genetic susceptibility, environmental factors, and an abnormal immune response of the intestinal immune system to commensal microorganisms. The gut microbiota and its metabolites play a pivotal role in maintaining intestinal immune homeostasis. Recent advances indicate that dysbiosis of the microbiota is accompanied by alterations in its metabolic functions. Abnormal levels of key metabolites, particularly short-chain fatty acids (SCFAs), tryptophan derivatives, and secondary bile acids, are clo
View details →DOI: 10.3389/fimmu.2026.1780865Cited by 11 Negative / Null Result ReportEngineering
Tianxin Hou, S X Liu, Weiyu Mao et al. · 2026 · International Journal of Pavement Engineering
The dynamic response analysis of aircraft and rigid pavement is critical for runway design and roughness evaluation. Existing methods typically assume fixed aircraft parameters, but actual variations in aircraft weight, landing gear, and…
View details →DOI: 10.1080/10298436.2026.2666268Cited by 11 