A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
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S.J.H. Bredie, Miek C. Jong · 2011 · Journal of Cardiovascular Pharmacology
BACKGROUND: Medicinal treatment of vasospastic Raynaud phenomenon is limited to primarily vasodilator medicines. OBJECTIVE: To explore the possible beneficial effects and tolerability of 120 mg two times a day of Ginkgo Biloba special…
Bożena Nejman-Faleńczyk, Beata Nadratowska-Wesołowska, Agnieszka Szalewska-Pałasz et al. · 2010 · Microbiology
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that…
Zouhaier Aloui, Mekki Hamdaoui, Samir Maktouf · 2024 · Transnational Corporation Review
This paper examines the moderating role of governance in the effect of Foreign Direct Investment (FDI) on poverty using simultaneous equations models for sub-Saharan African, Asian, Latin American and Eastern European countries over the…
Kam Ng, Todd Sullivan · 2017 · Geotechnical Research
In Wyoming, pile foundations for bridges are often driven on rock materials because of the state’s shallow bedrock stratigraphy. Unfortunately, no static analysis methods are currently available for estimating the resistance of these…
Anthony N. Reffi, Caitlin M. Pinciotti, Holly K. Orcutt · 2018 · Journal of Interpersonal Violence
Institutional betrayal reflects the failings of a trusted institution to prevent or respond appropriately to negative experiences. Following sexual assault, survivors who encounter institutional betrayal may experience greater distress and…
Alexander D. Stajković, Jessica M. Greenwald, Kayla Stajkovic · 2022 · Journal of Organizational Behavior
Summary The effects of primed money have received widespread attention in social psychology but not in the organizational literature. This research examines whether priming money causes people to think and behave in ways consistent with…
Guangsheng Song, Zhihui Qian, Xiangyu Liu et al. · 2023 · Advanced Functional Materials
Abstract Degenerative disc disease (DDD) has become a significant public health issue worldwide. This can result in loss of spinal function affecting patient health and quality of life. Artificial total disc replacement (A‐TDR) is an…
Esra Yiğit, Fikri Gökpınar · 2010 · Communications Faculty Of Science University of Ankara Series A1Mathematics and Statistics
The classical F-test to compare several population means depends on the assumption of homogeneity of variance of the population and the normality. When these assumptions especially the equality of variance is dropped, the classical F-test fails to reject the null hypothesis even if the data actually provide strong evidence for it. This can be considered a serious problem in some applications, especially when the sample size is not large. To deal with this problem, a number of tests are available in the literature. In this study, the Brown-Forsythe, Weerahandiís Generalized F, Parametric Bootst
Damian J. Ruck, R. Alexander Bentley, Alberto Acerbi et al. · 2017 · Advances in Complex Systems
Here, we test Neutral models against the evolution of English word frequency and vocabulary at the corpus scale, as recorded in annual word frequencies from three centuries of English language books. Against these data, we test both static…
Joshua K. Hartshorne, Lauren Skorb, Sven L. Dietz et al. · 2019 · Collabra Psychology
We report the first set of results in a multi-year project to assess the robustness – and the factors promoting robustness – of the adult statistical word segmentation literature. This includes eight total experiments replicating six different experiments. The purpose of these replications is to assess the reproducibility of reported experiments, examine the replicability of their results, and provide more accurate effect size estimates. Reproducibility was mixed, with several papers either lacking crucial details or containing errors in the description of method, making it difficult to ascert
Dominic Guitard, Leonie M. Miller, Ian Neath et al. · 2019 · Journal of Cognitive Psychology
People are better at recalling lists of high- than low-frequency words but as Parmentier, Comesãna, and Soares [(2017). Disentangling the effects of word frequency and contextual diversity on serial recall performance. Quarterly Journal of…
Chieffi S Iavarone A · 2015 · African Journal of Psychiatry
Attentional processes enhancing relevant information and attenuating competing irrelevant information are required for coherent and effective action. One of deficits that may characterize schizophrenia is the impairment of the ability in focusing on relevant information while inhibiting the irrelevant. The intrusion of irrelevant stimuli during information processing may impair cognitive and behavioral functioning. In this paper we review studies that investigated the vulnerability to distracting stimuli in schizophrenia by using visual interference paradigms, namely flanker, Stroop, and negat
Saurav Mallik, Zhongming Zhao · 2017 · Quantitative Biology
Background Marker detection is an important task in complex disease studies. Here we provide an association rule mining (ARM) based approach for identifying integrated markers through mutual information (MI) based statistically significant…
James L. Wade, Corey J. Langer, Mary W. Redman et al. · 2017 · Journal of Clinical Oncology
9054 Background: Lung-MAP (S1400) is a National Clinical Trials Network “umbrella” trial for previously-treated SqNSCLC. Sub-study S1400B included patients (pts) with tumors harboring PI3K mutations.Taselisib (GDC-0032), a potent, small…
Gabriel P. Langlois, Donald M. Arnold, Jayson Potts et al. · 2018 · Clinical Case Reports
Key Clinical Message Cyclic thrombocytopenia is often misdiagnosed as immune thrombocytopenia due to similar clinical features, a fact of significance because cyclic thrombocytopenia generally responds poorly to treatments used…
Subhankar Ghosh, Jayant Gupta, Arun Sharma et al. · 2022
Given a set S of spatial feature-types, its feature-instances, a study area, and a neighbor relationship, the goal is to find pairs such that C is a statistically significant regional colocation pattern in region rg. For example Caribou…
Yiqun Xie, Xiaowei Jia, Shashi Shekhar et al. · 2021 · ACM Transactions on Intelligent Systems and Technology
Cluster detection is important and widely used in a variety of applications, including public health, public safety, transportation, and so on. Given a collection of data points, we aim to detect density-connected spatial clusters with…
Mark Cornelis van der Plas, Krista Ingeborg Janssen, Nikolaos Pandis et al. · 2017 · The Angle Orthodontist
ABSTRACT Objective: To investigate the effect of acrylic capping, treatment duration, overjet, and lower incisor inclination on the posttreatment tooth position in patients treated with 2 Twin Block (TB) appliance versions. Materials and…
Arnaud Norena · 2024 · Frontiers in Psychology
Misophonia is a disorder of decreased tolerance to specific sounds, often produced by humans but not always, which can trigger intense emotional reactions (anger, disgust etc.). This relatively prevalent disorder can cause a reduction in…
Chengxi Zang, Yu Hou, Daoming Lyu et al. · 2024 · Translational Psychiatry
Machine Learning models trained from real-world data have demonstrated promise in predicting suicide attempts in adolescents. However, their transportability, namely the performance of a model trained on one dataset and applied to…
Mireia M. Ginesta, Zamira V. Díaz‐Riascos, Juli Busquets et al. · 2016 · Oncology Letters
Early detection of pancreatic and periampullary neoplasms is critical to improve their clinical outcome. The present authors previously demonstrated that DNA hypermethylation of adenomatous polyposis coli (APC), histamine receptor H2…
Miloš Krist, Pavel Munclinger · 2011 · Molecular Ecology
Extra-pair copulations (EPC) are the rule rather than an exception in socially monogamous birds, but despite widespread occurrences, the benefits of female infidelity remain elusive. Most attention has been paid to the possibility that…
Donna Kotsopoulos, Samantha Makosz, Joanna Zambrzycka et al. · 2019 · Early Child Development and Care
An enduring challenge in visual-spatial research has been to identify the factors contributing to individual differences in ability. This research investigated the overall, verbal, and nonverbal visual-spatial ability of 61 (34 boys)…
Kay Brauer, René T. Proyer · 2020 · Journal of Personality Assessment
Personality assessment typically relies on self-report questionnaires utilizing Likert-type scales. Recently, the Expanded format has been proposed as alternative, but research on the consequences of adapting Likert-like responses to…
Kumju Hwang, Jinsook Choi · 2021 · International Journal of Environmental Research and Public Health
Entrepreneurial failure is prevalent, and particularly when the COVID−19 crisis exacerbates the economic recession, it becomes even more prevalent. Entrepreneurs experience an intensive emotional crisis when their ventures fail, and this…
Isaac Shiri, Sebastian Balzer, Giovanni Baj et al. · 2024 · European Journal of Nuclear Medicine and Molecular Imaging
PURPOSE: Transthyretin amyloid cardiomyopathy (ATTR-CM) is a frequent concomitant condition in patients with severe aortic stenosis (AS), yet it often remains undetected. This study aims to comprehensively evaluate artificial intelligence-based models developed based on preprocedural and routinely collected data to detect ATTR-CM in patients with severe AS planned for transcatheter aortic valve implantation (TAVI). METHODS: Tc]-DPD) for the presence of ATTR-CM. Clinical, laboratory, electrocardiogram, echocardiography, invasive measurements, 4-dimensional cardiac CT (4D-CCT) strain data, and C
Yi Cao, Qing‐wei Guo, Ye‐da Wan · 2020 · Orthopaedic Surgery
Objective The T2 value of lumbar cartilage endplates was measured using the T2 mapping imaging technique, aiming to explore the correlation between the T2 value and Pfirrmann grading of intervertebral discs. Methods A total of 130 patients with lumbar spine MR examination due to persistent low back pain were enrolled, including 71 men and 59 women (age: 21–63 years). Lumbar Modic changes and Schmorl nodules were recognized by conventional T1WI and T2WI images in 49 patients, and these patients were excluded from the study. A total of 81 patients were enrolled in this study, including 45 men (4
Han‐Joo Lee, Amy R. Goetz, Jennifer E. Turkel et al. · 2014 · Anxiety Stress & Coping
BACKGROUND AND OBJECTIVES: Current cognitive-behavioral theorists conceptualize hypochondriasis as excessive health anxiety (HA). Growing evidence suggests that elevated HA is associated with attentional bias (AB) toward potential…
Fernanda Marcondes de Rezende, M. Haile‐Mariam, J.E. Pryce et al. · 2020 · Journal of Dairy Science
The use of information across populations is an attractive approach to increase the accuracy of genomic predictions for numerically small breeds and traits that are time-consuming and difficult to measure, such as male fertility in cattle.…
Barbora Weinbergerová, Tomáš Kabut, Iva Kocmanová et al. · 2020 · Scientific Reports
Invasive fungal disease (IFD) early diagnosis improves hematological patient survival. Non-culture-based methods may reduce diagnostic time to identify IFD. As complex data on the value of 1,3-β-D-glucan (BDG) from bronchoalveolar lavage fluid (BALF) compared to serum for the most frequent invasive pulmonary aspergillosis (IPA) diagnosis are scarce, particularly including evaluation of potential factors adversely affecting BDG assay, we provided prospective single-center analysis evaluating 172 episodes of pulmonary infiltrates with BDG detection in BALF and serum samples collected in parallel