A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19735 results in Negative / Null Result Report · page 11 of 658
Carlo Catassi, Debby Kryszak, Bushra Bhatti et al. · 2010 · Annals of Medicine
BACKGROUND: The natural history and the possible changes of celiac disease (CD) prevalence over time are still unclear. OBJECTIVES: 1) To establish whether loss of tolerance to gluten may occur at any age; 2) to investigate possible…
Mario Fiorini, Michael P. Keane · 2014 · Journal of Labor Economics
The allocation of children’s time among different activities may be important for cognitive and noncognitive development. Here, we exploit time use diaries from the Longitudinal Study of Australian Children to study the effects of time…
Arindam Samanta, Sangram Ganguly, Hirofumi Hashimoto et al. · 2010 · Geophysical Research Letters
The sensitivity of Amazon rainforests to dry‐season droughts is still poorly understood, with reports of enhanced tree mortality and forest fires on one hand, and excessive forest greening on the other. Here, we report that the previous…
Robert M. Bushman, Joseph D. Piotroski, Abbie J. Smith · 2011 · Journal of Business Finance & Accounting
Abstract: This paper explores direct relations between corporate investment behavior and the timeliness of accounting recognition of economic losses (TLR) reflected in a country's accounting regime. We explicitly investigate the extent to…
Fiona E. Freeman, Daniel J. Kelly · 2017 · Scientific Reports
Alginate is a commonly used bioink in 3D bioprinting. Matrix stiffness is a key determinant of mesenchymal stem cell (MSC) differentiation, suggesting that modulation of alginate bioink mechanical properties represents a promising strategy to spatially regulate MSC fate within bioprinted tissues. In this study, we define a printability window for alginate of differing molecular weight (MW) by systematically varying the ratio of alginate to ionic crosslinker within the bioink. We demonstrate that the MW of such alginate bioinks, as well as the choice of ionic crosslinker, can be tuned to contro
Carmelo Cennamo, Juan Santaló · 2019 · Organization Science
Platform-based technology ecosystems are new forms of organizing independent actors’ innovations around a stable product system. This collective organization is proving superior to traditional, vertically integrated systems in many sectors…
Jiawei Fan, Jiazhou Wang, Zhi Chen et al. · 2018 · Medical Physics
Purpose To develop an automated treatment planning strategy for external beam intensity‐modulated radiation therapy ( IMRT ), including a deep learning‐based three‐dimensional (3D) dose prediction and a dose distribution‐based plan…
David Figlio, Mark Rush, Lu Yin · 2013 · Journal of Labor Economics
This article presents the first experimental evidence on the effects of live versus Internet media of instruction. Students in a large introductory microeconomics course at a major research university were randomly assigned to live…
Sun Young Sung, Jin Nam Choi · 2013 · Journal of Organizational Behavior
The present study examines the effects of training and development on organizational innovation. We specifically suggest that the training and development investments of an organization affect its innovative performance by promoting…
Mohit Varshney, Jithin Thomas Parel, Neeraj Raizada et al. · 2020 · PLoS ONE
BACKGROUND: The pandemic of Corona Virus (COVID-19) hit India recently; and the associated uncertainty is increasingly testing psychological resilience of the masses. When the global focus has mostly been on testing, finding a cure and preventing transmission; people are going through a myriad of psychological problems in adjusting to the current lifestyles and fear of the disease. Since there is a severe dearth of researches on this issue, we decided to conduct an online survey to evaluate its psychological impact. METHODS: From 26th to 29th March an online survey (FEEL-COVID) was conducted u
Jens‐Ulrik Stæhr Jensen, Lars Hein, Bettina Lundgren et al. · 2011 · Critical Care Medicine
OBJECTIVE: For patients in intensive care units, sepsis is a common and potentially deadly complication and prompt initiation of appropriate antimicrobial therapy improves prognosis. The objective of this trial was to determine whether a…
Lawrence Fisher, Russell E. Glasgow, Lisa A. Strycker · 2010 · Diabetes Care
OBJECTIVE: To clarify previous findings that diabetes distress is related to glycemic control and self-management whereas measures of depression are not, using both binary and continuous measures of depression. RESEARCH DESIGN AND METHODS:…
Alessandro Doria, Andrzej T. Gałecki, Cathie Spino et al. · 2020 · New England Journal of Medicine
BACKGROUND: Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering of the serum urate level with allopurinol may slow the decrease in the glomerular filtration rate (GFR) in persons with type 1…
Yee Mei Heong, Widad Othman, Jailani Yunos et al. · 2011 · International Journal of Social Science and Humanity
Higher order thinking skills is an important aspect in teaching and learning especially at higher education institutions. Thinking skills practices are part of the generic skills that should be infused in all technical subjects. Students…
Manuela Angelucci, Dean Karlan, Jonathan Zinman · 2015 · American Economic Journal Applied Economics
We use a clustered randomized trial, and over 16,000 household surveys, to estimate impacts at the community level from a group lending expansion at 110 percent APR by the largest microlender in Mexico. We find no evidence of…
Ahmad El-Kharouf, Thomas J. Mason, Dan J. L. Brett et al. · 2012 · Journal of Power Sources
This paper presents the first part of a complete ex-situ characterisation of a wide range of commercial Gas Diffusion Layers (GDLs) used in low temperature and high temperature Proton Exchange Membrane (PEM) fuel cells. Physical and electrical characteristics of the GDLs are reported. The results show that the substrate structure has a significant effect on the mechanical and electrical properties of the GDL. Moreover, the Micro Porous Layer (MPL) structure determines the roughness of the surface, and affects the permeability and porosity of the GDL. It was found that the substrate treatment w
Brian A. Boyd, Grace T. Baranek, John Sideris et al. · 2010 · Autism Research
This study combined parent and observational measures to examine the association between aberrant sensory features and restricted, repetitive behaviors in children with autism (N=67) and those with developmental delays (N=42). Confirmatory…
James Y. Lau, Yuanyuan Yu, Raymond S. Tang et al. · 2020 · New England Journal of Medicine
BACKGROUND: It is recommended that patients with acute upper gastrointestinal bleeding undergo endoscopy within 24 hours after gastroenterologic consultation. The role of endoscopy performed within time frames shorter than 24 hours has not…
Eric T. Swanson · 2011 · Brookings Papers on Economic Activity
This paper undertakes a modern event-study analysis of Operation Twist and uses its estimated effects to assess what should be expected for the recent policy of quantitative easing by the Federal Reserve, dubbed “QE2.” The paper first…
Thomas Wicker, Heidrun Gundlach, M. Spannagl et al. · 2018 · Genome biology
BACKGROUND: Transposable elements (TEs) are major components of large plant genomes and main drivers of genome evolution. The most recent assembly of hexaploid bread wheat recovered the highly repetitive TE space in an almost complete chromosomal context and enabled a detailed view into the dynamics of TEs in the A, B, and D subgenomes. RESULTS: The overall TE content is very similar between the A, B, and D subgenomes, although we find no evidence for bursts of TE amplification after the polyploidization events. Despite the near-complete turnover of TEs since the subgenome lineages diverged fr
Dion Bongaerts, De Jong, FCJM, Driessen, JJAG · 2011 · EUR Research Repository (Erasmus University Rotterdam)
We derive an equilibrium asset pricing model incorporating liquidity risk, derivative assets, and short-selling due to hedging of non-traded risk. We show that, both for positive-net-supply assets and derivatives, the sign of liquidity…
Bruno Cassiman, Giovanni Valentini · 2015 · Strategic Management Journal
One novel implication of the open innovation paradigm is that inflows and outflows of knowledge are complementary. We argue that engaging simultaneously in buying and selling knowledge should allow firms to increase innovation outcomes. At…
Pieter T. J. Johnson, David W. Thieltges · 2010 · Journal of Experimental Biology
Growing interest in ecology has recently focused on the hypothesis that community diversity can mediate infection levels and disease ('dilution effect'). In turn, biodiversity loss--a widespread consequence of environmental change--can…
Emily Corner, Paul Gill · 2014 · Law and Human Behavior
We test whether significant differences in mental illness exist in a matched sample of lone- and group-based terrorists. We then test whether there are distinct behavioral differences between lone-actor terrorists with and without mental…
Rebecca Landa, Katherine C. Holman, Allison H. O’Neill et al. · 2010 · Journal of Child Psychology and Psychiatry
BACKGROUND: Social and communication impairments are core deficits and prognostic indicators of autism. We evaluated the impact of supplementing a comprehensive intervention with a curriculum targeting socially synchronous behavior on…
Adam J. Bewick, Lexiang Ji, Chad E. Niederhuth et al. · 2016 · Proceedings of the National Academy of Sciences
In plants, CG DNA methylation is prevalent in the transcribed regions of many constitutively expressed genes (gene body methylation; gbM), but the origin and function of gbM remain unknown. Here we report the discovery that Eutrema…
Owen R. Cooper, R. S. Gao, D. W. Tarasick et al. · 2012 · Journal of Geophysical Research Atmospheres
This analysis provides an up‐to‐date assessment of long‐term (1990–2010) rural ozone trends using all available data in the western (12 sites) and eastern (41 sites) USA. Rather than focus solely on average ozone values or air quality…
C. Thanasas, George N. Papadimitriou, Charalambos Charalambidis et al. · 2011 · The American Journal of Sports Medicine
BACKGROUND: Chronic lateral elbow epicondylitis is a tendinosis with angiofibrolastic degeneration of the wrist extensors' origin. Healing of this lesion is reported with the use of autologous blood as well as with platelet-rich plasma…
A. M. S. A. Qados · 2011 · Journal of the Saudi Society of Agricultural Sciences
The effect of sodium chloride (NaCl) concentrations (0.0, 60, 120, 240 mM) on growth, osmotic potential, chlorophyll content, protein content of (Vicia faba L.) seedlings was investigated. NaCl caused an increase in plant height with low…
Heather K. Spence Laschinger, Ashley L. Grau, Joan Finegan et al. · 2010 · Journal of Advanced Nursing
AIM: This paper is a report of a study conducted to test a model linking new graduate nurses' perceptions of structural empowerment to their experiences of workplace bullying and burnout in Canadian hospital work settings using Kanter's…