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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20211 results in Negative / Null Result Report · page 104 of 674

Negative / Null Result Report

Climate Change and Human Activities, the Significant Dynamic Drivers of Himalayan Goral Distribution (Naemorhedus goral)

Shiekh Marifatul Haq, Muhammad Waheed, Riyaz Ahmad et al. · 2023 · Biology

The distribution of large ungulates is more often negatively impacted by the changing climate, especially global warming and species with limited distributional zones. While developing conservation action plans for the threatened species…

View details →DOI: 10.3390/biology12040610Cited by 21
Negative / Null Result Report

Small Social Incentives Did Not Improve the Survey Response Rate of Patients Who Underwent Orthopaedic Surgery: A Randomized Trial

Hunter Warwick, Carolyn Hutyra, Cary Politzer et al. · 2019 · Clinical Orthopaedics & Related Research

Abstract Background The generalizability of data derived from patient-reported outcome measures (PROMs) depends largely on the proportion of the relevant population that completes PROM surveys. However, PROM survey responses remain low,…

View details →DOI: 10.1097/corr.0000000000000732Cited by 21
Negative / Null Result Report

Low-phytate wholegrain bread instead of high-phytate wholegrain bread in a total diet context did not improve iron status of healthy Swedish females: a 12-week, randomized, parallel-design intervention study

Michael Hoppe, Alastair B. Ross, Cecilia Svelander et al. · 2018 · European Journal of Nutrition

Abstract Purpose To investigate the effects of eating wholegrain rye bread with high or low amounts of phytate on iron status in women under free-living conditions. Methods In this 12-week, randomized, parallel-design intervention study,…

View details →DOI: 10.1007/s00394-018-1722-1Cited by 21
Negative / Null Result ReportOpen accessMedicine

Performance of arthroscopic irrigation systems assessed with automatic blood detection

Gabriëlle J. M. Tuijthof, M. M. de Vaal, I. N. Sierevelt et al. · 2011 · Knee Surgery Sports Traumatology Arthroscopy

PURPOSE: During arthroscopies, bleeding episodes occur as a result of tissue damage. Irrigation systems assist in minimizing these disturbances. The performance of three arthroscopic irrigation systems in clearing bleeding episodes was…

View details →DOI: 10.1007/s00167-011-1495-zCited by 21
Negative / Null Result ReportOpen accessMedicine

Estimated GFR and Mortality in Older Men: Are All eGFR Formulae Equal?

Muna Canales, Terri Blackwell, Areef Ishani et al. · 2016 · American Journal of Nephrology

<b><i>Background:</i></b> Recently, the first estimated glomerular filtration rate (eGFR) formula specifically developed for community-dwelling older adults, the Berlin Initiative Study Equation 2 (BIS2), was…

View details →DOI: 10.1159/000445757Cited by 21
Negative / Null Result Report

Monobenzoporphyrins as Sensitizers for Dye‐Sensitized Solar Cells: Observation of Significant Spacer‐Group Effect

R. G. Waruna Jinadasa, Bihong Li, Benjamin Schmitz et al. · 2016 · ChemSusChem

Abstract A series of monobenzoporphyrins ( WH1 – WH4 ) bearing different conjugated spacer groups were designed and synthesized as sensitizers for dye‐sensitized solar cells. Although a phenyl spacer only has a minimal impact on the…

View details →DOI: 10.1002/cssc.201600619Cited by 21
Negative / Null Result Report

Effect of significant data loss on identifying electric signals that precede rupture estimated by detrended fluctuation analysis in natural time

E. S. Skordas, N. V. Sarlis, P. A. Varotsos · 2010 · Chaos: An Interdisciplinary Journal of Nonlinear Science

Electric field variations that appear before rupture have been recently studied by employing the detrended fluctuation analysis (DFA) to quantify their long-range temporal correlations. These studies revealed that seismic electric signal…

View details →DOI: 10.1063/1.3479402Cited by 21
Negative / Null Result Report

Anomalous metals: From “failed superconductor” to “failed insulator”

Xinyang Zhang, Alexander Palevski, Aharon Kapitulnik · 2022 · Proceedings of the National Academy of Sciences

Resistivity saturation is found on both superconducting and insulating sides of an “avoided” magnetic-field-tuned superconductor-to-insulator transition (H-SIT) in a two-dimensional In/InO x composite, where the anomalous metallic behavior…

View details →DOI: 10.1073/pnas.2202496119Cited by 21
Negative / Null Result ReportOpen accessMedicine

Significant Association of Serum Adiponectin and Creatine Kinase-MB Levels in ST-Segment Elevation Myocardial Infarction

Tomoaki Natsukawa, Norikazu Maeda, Shiro Fukuda et al. · 2017 · Journal of Atherosclerosis and Thrombosis

AIMS: Adiponectin, an adipocyte-specific secretory protein, abundantly exists in the blood stream while its concentration paradoxically decreases in obesity. Hypoadiponectinemia is one of risks of cardiovascular diseases. However, impact…

View details →DOI: 10.5551/jat.38232Cited by 21
Negative / Null Result ReportSocial Sciences

Do minority-language and majority-language students benefit from pedagogical translanguaging in early foreign language development?

Holger Hopp, Teresa Kieseier, Jenny Jakisch et al. · 2021 · Multilingua

Abstract This paper reports findings of a project on pedagogical translanguaging (PTL) among 128 fourth-grade students learning English as a foreign language (EFL) in German primary schools. Over a period of six months, 20% of lesson time…

View details →DOI: 10.1515/multi-2020-0164Cited by 21
Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

Fundamental Analysis VS Technical analysis: The Comparison of Two Analysis in Malaysia Stock Market

Shaharudin Jakpar, Michael Tinggi, Akmal Hisham Tak et al. · 2018 · UNIMAS Review of Accounting and Finance

This study is conducted to analyse the credibility of the fundamental analysis and technical analysis on predicting the stock return and compare both models to determine which model is more credible to be used as a good trading strategy by…

View details →DOI: 10.33736/uraf.1208.2018Cited by 21
Negative / Null Result ReportOpen accessNeuroscience

Propensity or diversity? Investigating how mind wandering influences the incubation effect of creativity

Shan-Chuan Teng, Yunn-Wen Lien · 2022 · PLoS ONE

Mind wandering has been argued to be beneficial for breaking through mental impasses, which leads to better creative performance upon a second attempt (i.e., the incubation effect). However, the evidence is inconsistent. Different from the propensity for mind wandering that has been the focus of past studies, in this study we further examined the role of diversity (i.e., non-repetitiveness of mind wandering respective to its content) and types of mind wandering along the dimensions of intentionality and awareness during incubation when engaging in a 0-back task (a mind wandering-prone conditio

View details →DOI: 10.1371/journal.pone.0267187Cited by 21
Negative / Null Result ReportPsychology

Structured assessment of suicide risk in a psychiatric emergency service: Psychometric evaluation of the Nurses’ Global Assessment of Suicide Risk scale (NGASR)

Mark van Veen, Inge van Weeghel, Bauke Koekkoek et al. · 2014 · International Journal of Social Psychiatry

BACKGROUND: Risk of suicide is notoriously difficult to assess, and no gold standard is available, in terms of an instrument of first choice. Many different instruments are in use, among which are some that are not properly…

View details →DOI: 10.1177/0020764014543311Cited by 21
Negative / Null Result ReportOpen accessMedicine

Cystatin C– and Creatinine-Based Estimates of Renal Function and Their Value for Risk Prediction in Patients with Acute Coronary Syndrome: Results from the PLATelet Inhibition and Patient Outcomes (PLATO) Study

Axel Åkerblom, Lars Wallentin, Anders Larsson et al. · 2013 · Clinical Chemistry

BACKGROUND: The estimated glomerular filtration rate (eGFR) independently predicts cardiovascular death or myocardial infarction (MI) and can be estimated by creatinine and cystatin C concentrations. We evaluated 2 different cystatin C…

View details →DOI: 10.1373/clinchem.2012.200709Cited by 21
Negative / Null Result ReportOpen accessMedicine

The American Association for the Surgery of Trauma renal injury grading scale: Implications of the 2018 revisions for injury reclassification and predicting bleeding interventions

Sorena Keihani, Douglas Rogers, Bryn Putbrese et al. · 2019 · The Journal of Trauma: Injury, Infection, and Critical Care

BACKGROUND: In 2018, the American Association for the Surgery of Trauma (AAST) published revisions to the renal injury grading system to reflect the increased reliance on computed tomography scans and non-operative management of high-grade…

View details →DOI: 10.1097/ta.0000000000002572Cited by 21
Negative / Null Result ReportOpen accessMedicine

Predicting vaginal birth after previous cesarean: Using machine‐learning models and a population‐based cohort in Sweden

Charlotte Lindblad Wollmann, Kyle D. Hart, Can Liu et al. · 2020 · Acta Obstetricia Et Gynecologica Scandinavica

INTRODUCTION: Predicting a woman's probability of vaginal birth after cesarean could facilitate the antenatal decision-making process. Having a previous vaginal birth strongly predicts vaginal birth after cesarean. Delivery outcome in…

View details →DOI: 10.1111/aogs.14020Cited by 21
Negative / Null Result ReportOpen accessSocial Sciences

Situational experience around the world: A replication and extension in 62 countries

Daniel Lee, Gwendolyn Gardiner, Erica Baranski et al. · 2020 · Journal of Personality

OBJECTIVE: The current study seeks to replicate and extend principal findings reported in The World at 7:00, a project that examined the psychological experience of situations in 20 countries. METHOD: Data were collected from participants…

View details →DOI: 10.1111/jopy.12558Cited by 21
Negative / Null Result ReportOpen accessMedicine

Treatment with the copper compound CuATSM has no significant effect on motor neuronal pathology in patients with ALS

Yue Yang, Dominic B. Rowe, Heather McCann et al. · 2023 · Neuropathology and Applied Neurobiology

AIMS: Although the orally available brain-penetrant copper compound CuATSM has demonstrated promising effects in SOD1-linked mouse models, the impact of CuATSM on disease pathology in patients with amyotrophic lateral sclerosis (ALS) remains unknown. METHODS: The present study set out to address this deficit by performing the first pilot comparative analysis of ALS pathology in patients that had been administered CuATSM and riluzole [N = 6 cases composed of ALS-TDP (n = 5) and ALS-SOD1 (n = 1)] versus riluzole only [N = 6 cases composed of ALS-TDP (n = 4) and ALS-SOD1 (n = 2)]. RESULTS: Our re

View details →DOI: 10.1111/nan.12919Cited by 21
Negative / Null Result ReportOpen accessMedicine

Barriers to Participation in a Community-Based Program to Control Transmission of Taenia solium in Peru

Michelle Beam, Angela G. Spencer, Lauralee Fernandez et al. · 2018 · American Journal of Tropical Medicine and Hygiene

larvae (neurocysticercosis) is a leading cause of preventable epilepsy worldwide. Effective and sustainable strategies to control parasite transmission in rural endemic communities are needed to prevent the disease. Surveillance and…

View details →DOI: 10.4269/ajtmh.17-0929Cited by 21
Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

Peculiarities of export structure in Lithuania: synthesis and analysis

Irina Travkina, Manuela Tvaronavičienė · 2015 · Journal of Entrepreneurship and Sustainability Issues

The research paper discusses the relationship between international trade, especially export, and the economic growth, presented by GDP, in Lithuania over the period of 2000-2015 years. The analysis is started by the historical review of possible types of relationships between exports and economic growth. Furthermore, the paper presents four theoretical propositions as export-led growth (1), growth-driven export (2), a feedback relationship (3) and simple contemporaneous relationship (4). This study examines the importance of the export-led growth hypothesis for Lithuania. The testing is based

View details →DOI: 10.9770/jesi.2015.2.4(7)Cited by 21
Negative / Null Result ReportOpen accessMedicine

Fatty acid amide hydrolase binding is inversely correlated with amygdalar functional connectivity: a combined positron emission tomography and magnetic resonance imaging study in healthy individuals

Duncan G.J. Green, Jinhee Kim, Stephen J. Kish et al. · 2021 · Journal of Psychiatry and Neuroscience

Background: Upregulation of the endocannabinoid enzyme fatty acid amide hydrolase (FAAH) has been linked to abnormal activity in frontoamygdalar circuits, a hallmark of posttraumatic stress disorder. We tested the hypothesis that FAAH…

View details →DOI: 10.1503/jpn.200010Cited by 21
Negative / Null Result ReportOpen accessMedicine

Guapiaçu virus, a new insect-specific flavivirus isolated from two species of Aedes mosquitoes from Brazil

Geovani de Oliveira Ribeiro, Antônio Charlys da Costa, Danielle Elise Gill et al. · 2021 · Scientific Reports

Classical insect-flaviviruses (cISFVs) and dual host-related insect-specific flavivirus (dISFV) are within the major group of insect-specific flavivirus. Remarkably dISFV are evolutionarily related to some of the pathogenic flavivirus, such as Zika and dengue viruses. The Evolutionary relatedness of dISFV to flavivirus allowed us to investigate the evolutionary principle of host adaptation. Additionally, dISFV can be used for the development of flavivirus vaccines and to explore underlying principles of mammalian pathogenicity. Here we describe the genetic characterization of a novel putative

View details →DOI: 10.1038/s41598-021-83879-6Cited by 21
Negative / Null Result ReportOpen accessAgricultural and Biological Sciences

Introducing the No-Significant-Effect Concentration

Rebecca Fisher, David R. Fox · 2023 · Environmental Toxicology and Chemistry

The no-effect concentration (NEC) is the preferred threshold metric for single-species toxicity tests applied to derive safe concentration thresholds for contaminants in the environment for use in species sensitivity distributions.…

View details →DOI: 10.1002/etc.5610Cited by 21
Negative / Null Result ReportOpen accessMedicine

Genome‐wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward‐related ventral striatum activity in African‐ and European‐Americans

Leah Wetherill, Dongbing Lai, Emma C. Johnson et al. · 2019 · Genes Brain & Behavior

Abstract Genetic influences on alcohol and drug dependence partially overlap, however, specific loci underlying this overlap remain unclear. We conducted a genome‐wide association study (GWAS) of a phenotype representing alcohol or illicit…

View details →DOI: 10.1111/gbb.12580Cited by 21
Negative / Null Result ReportOpen accessEnvironmental Science

Artificial agri‐environment scheme ponds do not replicate natural environments despite higher aquatic and terrestrial invertebrate richness and abundance

Marina Reyne, Myles Nolan, Henry McGuiggan et al. · 2020 · Journal of Applied Ecology

Abstract Farmland ponds are a highly threatened freshwater habitat which has undergone dramatic losses during the last 200 years due to land drainage schemes and agricultural intensification. Agri‐environment schemes (AES) incentivize farmers to adopt farming methods to benefit biodiversity, yet there are a paucity of data evaluating the success of artificially created AES ponds as analogues of natural ponds in an attempt to recreate lost environments. We examined variation in environmental parameters and aquatic and terrestrial invertebrate communities between 38 natural ponds and 91 artifici

View details →DOI: 10.1111/1365-2664.13738Cited by 21