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403 real negative results, null findings, and replication failures · Replication Failure. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Replication FailureOpen accessMedicine

Prevalence and concomitance of diabetic peripheral sensory neuropathy and lower limb peripheral arterial disease in type II diabetics and its correlation with obesity.

Solanki JD, Shah AP, Lalwani N et al. · 2025 · Journal of family medicine and primary care

Introduction Among type 2 diabetics (T2D), macrovascular complication lower limb Peripheral Arterial Disease (PAD) and microvascular complication Diabetic Peripheral Sensory Neuropathy (DPSN) have scarcely studied concordance and their…

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Replication FailureOpen accessMedicine

Lack of association between <i>MALAT1</i> rs591291 and rs3200401 polymorphisms and venous malformation risk in the Chinese pediatric population.

Lin X, Ou J, Wu G et al. · 2025 · Biochemistry and biophysics reports

Introduction Venous malformations are the most common congenital vascular anomaly, accounting for 65 % of all congenital vascular abnormalities. This study aims to investigate the correlation between genetic polymorphisms of MALAT1 and the…

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Replication FailureMedicine

Impact of Vitamin D Supplementation on IVF Outcomes in Vitamin D-Deficient Poor Responders: a Randomized Controlled Trial.

Mirsharifi MS, Shirdel S, Ghaderi E et al. · 2026 · Reproductive sciences (Thousand Oaks, Calif.)

OBJECTIVE: This study aimed to evaluate the effect of vitamin D supplementation on in vitro fertilization (IVF) outcomes in poor responder women with vitamin D deficiency, focusing on fertilization rates, oocyte quality, and pregnancy…

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Replication FailureMedicine

UGT76B1 and 41 Additional Arabidopsis UDP-Glycosyltransferases Show No Detectable In Vitro Glycosylation Activity Toward <i>N</i>-Hydroxypipecolic Acid.

Bao J, Uchiyama T, Kusunoki K et al. · 2026 · Life (Basel, Switzerland)

N -hydroxypipecolic acid (NHP) is a key mobile signal in systemic acquired resistance in plants, and its glycosylation has been proposed to regulate immune signaling. Previous studies have demonstrated that the UDP-glycosyltransferase…

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Replication FailureOpen accessMedicine

Platelet desialylation, apoptosis, and T-lymphocyte-mediated immune dysregulation: unveiling the pathways of platelet clearance in platelet transfusion refractoriness.

Zhou Y, Zhong Z, Mo H et al. · 2026 · Research and practice in thrombosis and haemostasis

Background Platelet transfusion refractoriness (PTR) is a clinical challenge that can be classified into nonimmunologic and immunologic types, the latter resulting from both platelet alloimmunization and autoimmunity. Recent studies have…

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Replication FailureOpen accessMedicine

Searching for vertically transmitted endosymbionts in over 4,000 wild strains of three self-fertilizing <i>Caenorhabditis</i> species.

O'Connor LM, Singh A, Luallen RJ et al. · 2026 · microPublication biology

Vertically transmitted endosymbionts are microbes that live inside host cells and are transmitted between parent and offspring. Free-living nematodes interact with a wide variety of microbes but no vertically transmitted microbes have been…

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Replication FailureMedicine

Balancing the Game: The Relationship of Lower-Limb Asymmetry With Youth Soccer (Football) Performance - Laboratory vs. Field Insights.

Bartusevičius D, Stanislovaitienė J, Conte D · 2026 · Journal of strength and conditioning research

Abstract Bartusevičius, D, Stanislovaitienė, J, and Conte, D. Balancing the game: the relationship of lower-limb asymmetry with youth soccer (football) performance - laboratory vs. field insights. J Strength Cond Res XX(X): 000-000,…

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Replication FailureOpen accessNutritional diseases. Deficiency diseases

Sex-specific associations between type 2 diabetes and muscle health in middle-aged adults

Yijia Wang, Songting Gao, Qiang Xu et al. · 2025 · Diabetology & Metabolic Syndrome

Abstract Background Type 2 diabetes mellitus (T2DM) and sarcopenia have emerged as significant public health challenges that disproportionately affect middle-aged adults. However, the relationship between T2DM and muscle parameters in this critical age remains inadequately elucidated. Methods We conducted a comprehensive analysis of cross-sectional data derived from 2,446 middle-aged participants (aged 40–59 years; 1,230 men and 1,216 women) enrolled in the National Health and Nutrition Examination Survey (NHANES) 2011–2014. T2DM was defined by physician-confirmed diagnosis and/or glycohemoglo

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Replication FailureOpen accessInternal medicine

Correlation between Vitamin D Receptor Gene FOKI and BSMI Polymorphisms and the Susceptibility to Pulmonary Tuberculosis in an Indonesian Batak-ethnic Population

Bintang Y.M. Sinaga, Muhammad Amin, Yahwardiah Siregar et al. · 2014 · Acta Medica Indonesiana

Aim: to explore the role of FokI and BsmI polymorphisms the VDR gene in the susceptibility to pulmonary tuberculosis (PTB) in an Indonesian Batak ethnic population. Methods: matched case-control study was conducted on 76 PTB patients and 76 healthy normal control. Genetic polymorphisms of Vitamin D Receptor (VDR) gene were analysed using PCR-RFLP. Results: the frequencies of FokI genotypes were FF 35.5%, Ff 55.3%, ff 9.2% for PTB patients and FF 39.5%, Ff 44.7.% and ff 15.8% for normal control. The BsmI genotypes frequencies were BB 0%, Bb 68.4%, bb 31.6% for TB patients and BB 2.6%, Bb 23.7%

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Replication FailureOpen access

Effect of feeding low protein diets supplemented with selected essential amino acids on growth performance and gut health in early weaned Large White Yorkshire piglets

N. Mohan, M. Dipu, K. Ally et al. · 2023 · Journal of Veterinary and Animal Sciences

A study was conducted to assess the effect of feeding low protein diets supplemented with selected amino acids on growth performance and gut health in early weaned Large White Yorkshire piglets. Thirty Large White Yorkshire female piglets…

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