e-ISSN: Pending
Replication FailureOpen accessMedicine

Assessing patient risk, benefit, and outcomes in drug development: A decade of ramucirumab clinical trials.

Khan A; Khan H; Hughes GK; Ladd C; McIntire R; Gardner B; Peña AM; Schoutko A · 2024 · Cancer medicine

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Objective This study aims to evaluate published clinical trials of ramucirumab to assess the risk/benefit profile and burden over time for patients. Background The burden of oncologic drug development on patients paired with increasing…

Excerpt shown for reference under fair use — read the full paper at the publisher.

About to run something similar?

Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.

WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.

Metadata source: Europe PMC · DOI 10.1002/cam4.7130