β-Catenin Does Not Co-activate Vitamin D Receptor-mediated Transcription in Osteoblastic and Non-osteoblastic Cells.
Nguyen TT; Kanemoto Y; Sawada T; Zhang J; Kurokawa T; Kato S · 2026 · Bioscience, biotechnology, and biochemistry
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Vitamin D (VD) and Wnt signaling both play important roles in bone metabolism and are targeted in osteoporosis therapy. Combination treatment with VD derivatives and anti-sclerostin antibodies that activate Wnt signaling improves clinical…
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Metadata source: Europe PMC · DOI 10.1093/bbb/zbag084