Negative / Null Result ReportOpen accessPlant culture
Simone Pietro Garofalo, Vincenzo Giannico, Beatriz Lorente et al. · 2024 · Frontiers in Plant Science
IntroductionIn the context of climate change, monitoring the spatial and temporal variability of plant physiological parameters has become increasingly important. Remote spectral imaging and GIS software have shown effectiveness in mapping field variability. Additionally, the application of machine learning techniques, essential for processing large data volumes, has seen a significant rise in agricultural applications. This research was focused on carob tree, a drought-resistant tree crop spread through the Mediterranean basin. The study aimed to develop robust models to predict the net assim
View details →Negative / Null Result ReportOpen accessDentistry
Sara Ordooei Javan, Reza Movahedian, Somayeh Hosseini Tabatabaei · 2025 · Dental Research Journal
Background: During the incremental technique of composite restorations, it is possible to be exposed to contamination of the oral environment. This study aimed to compare the effect of saliva contamination and different methods of saliva decontamination on microshear bond strength within composite surfaces. Materials and Methods: This in vitro study created 24 rectangular XT composite blocks using a silicone mold (24 mm × 10 mm × 10 mm). The blocks were divided into eight groups as follows: Group 1: Control group (without contamination); Group 2: Contaminated with saliva; Group 3: saliva + dri
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Jiagen Wen, Meizi Zeng, Zhaoqian Liu et al. · 2019 · Journal of Pharmacological Sciences
Metformin is the most widely used drug among type 2 diabetes mellitus patients. However, drug interaction on metformin will influence its glucose-lowering effect or increase its side effect of lactic acidosis. In this study, a randomized, two-stage, crossover study was conducted to unveil the potential drug interaction between metformin and the anti-hypertension drug, telmisartan. Totally, 16 healthy Chinese male volunteers were enrolled. Blood samples from various time-points after drug adminstration were analyzed for metformin quantification. Oral glucose tolerance test (OGTT) was conducted
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Yahya Irwanto · 2012 · Indonesian Journal of Obstetrics and Gynecology
Objective: To know whether the expression of Fas Ligand has correlation with incidene of metastasis of pelvic lymph node and lymph-vascular stromal invasion (LVSI). Methods: All patients diagnosed of cervical cancer stage IB or IIA who underwent radical hysterectomy in Dr. Cipto Mangunkusumo Central General Hospital from January 2008 until December 2009 were included in analytic cross sectional study. We tested expression of Fas Ligand in cervical cancer specimen by immunohystochemistry with monoclonal antibody. The expression of Fas Ligand was compared between the group of patients with a pos
View details →Negative / Null Result ReportOpen accessScience (General)
Afsoon Motallebi, Mehdi Fathi, Fatemeh Mazhari et al. · 2024 · Heliyon
Background: This randomized clinical trial (RCT) investigated whether hypnosis would lead to favorable outcomes in reducing anxiety, enhancing cooperation, and improving physiological responses in school-aged children undergoing tooth extraction compared to nitrous oxide/oxygen (N2O/O2) and conventional behavior guidance (CBG). Methods: Sixty-six school-aged children (mean age: 7.87 ± 1.18 years) who needed one posterior primary tooth extraction were included. Children with low-to-moderate anxiety were randomly divided into three groups (n = 22 each): hypnosis, N2O/O2, and CBG. Anxiety levels
View details →Negative / Null Result ReportOpen accessMedicine
Joan Hermosura, Everett Lohman, Brenda Bartnik-Olson et al. · 2024 · PLoS ONE
Objectives The main purpose of this research study was to compare mean modified straight-leg raise test (mSLR) and hamstring muscle length (HL) between chronic non-specific low back pain (LBP) and healthy subjects to understand the possibility of neuropathic causes in LBP population as it may impact the diagnosis and treatment of LBP. Another purpose was to compare mean mSLR between those with lumbar nerve root impingement and those without as determine by magnetic resonance imaging (MRI). Methods The design of the study is cross sectional and included 32 subjects with ages ranging from 18-50
View details →Negative / Null Result ReportOpen accessDentistry
Sonam Mufti, Sarvagna Mayank Dadawala, Phoram Patel et al. · 2017 · Contemporary Clinical Dentistry
Background: One of the most common aesthetic problem encountered in the field of periodontology is gingival recession, which is, perceived by the patients as increase in length of teeth. The treatment of buccal gingival recession is a common requirement due to aesthetic concern or root sensitivity. This study was planned to evaluate the efficacy of PRF membrane compared to that of CTG in Miller's class I gingival recessions. Materials and Methods: 32 sites with Miller's Class I gingival recessions, out of which 16 sites received PRF (test) and 16 sites received CTG (control). Each patient had
View details →Negative / Null Result ReportOpen accessDentistry
Huiying Li, Huiying Li, Tong Wang et al. · 2025 · Frontiers in Dental Medicine
BackgroundReattachment of root fragments with appropriate adhesive materials is expected to be the last conservative treatment for preserving teeth with vertical root fractures (VRFs).ObjectiveThis study evaluated the biocompatibility of 4-META/MMA-TBB resin for root repair, compared with iRoot BP Plus, Fuji IX GIC, and Clearfil SA Luting. Fracture resistance and microleakage of the reattached roots were also tested.MethodsThe biocompatibility of set materials was evaluated on L929 fibroblasts. Cell Counting Kit-8 (CCK-8) assay, live/dead cells staining and flow cytometry were used to assess c
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Saixin Li, Zheng Wang, Zheng Li et al. · 2024 · BMC Gastroenterology
Abstract Background T-tube cholangiography and choledochoscopy are commonly used techniques for detecting residual bile duct stones after biliary surgery. However, the utility of routine cholangiography before T-tube removal needs further investigation. This study aims to evaluate the diagnostic efficacy of various methods for detecting residual calculi following biliary surgery. Methods We retrospectively analyzed the clinical data of 287 adult patients who underwent common bile duct exploration with T-tube drainage, followed by T-tube cholangiography and choledochoscopy, at the Department of
View details →Negative / Null Result ReportOpen accessEnvironmental sciences
Fahrimal Yudha, Asmilia Nuzul, Aisyah Siti et al. · 2020 · E3S Web of Conferences
As one of the Local wisdom in Aceh, farmer prefers raising polled cow than horned cow for breeding purposes. They believe pole cow is more resilient in harsh conditions and reproductively better than the horned cow. The aim of this study was to evaluate blood profile and blood biochemistry of the aceh polled and horned cow. The blood profile examined includes erythrocyte value, erythrocyte indices MCV (Mean Corpuscular Volume), MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), thrombocyte, leukocyte, hematocrit, and hemoglobin, while blood biochemistry includ
View details →Negative / Null Result ReportOpen accessEngineering (General). Civil engineering (General)
Amar Thamir Hamad, Musaab Al-Tamer · 2011 · Tikrit Journal of Engineering Sciences
In this study the characteristics of raw and treated wastewater from Ninava drug factory were evaluated. The results revealed that the strength of raw wastewater can be classified as medium concentrated wastewater with respect to its BOD5 since the average value is 231.7 mg/l. In addition a strong correlations were found between many characteristics of raw waste. The characteristics of produced effluent from waste water treatment plant of the factory were within the Iraqi specification for the disposed wastewater constraints in 1997, where the average is 7.8 for pH, 40mg/l for SS, 2.8 mg/l for
View details →Negative / Null Result ReportOpen accessMedicine
Hadi Ghaedi, Siamak Takesh, Ebrahim Banitalebi · 2020 · Journal of Shahrekord University of Medical Sciences
Background and aims: Exercise training is a well-established therapeutic tool for treating type 2 diabetes. The purpose of this study is to examine the beneficial effects of personalized sprint interval training (SIT) and combined aerobic endurance and resistance training (Com) on insulin resistance and glycated hemoglobin A1c (HbA1c) concentration in women with type 2 diabetes. Methods: Fifty-two overweight female type 2 diabetic patients (age 45-60 years and body mass index [BMI] > 30) with HbA1c value of 6.5% or higher and fasting blood glucose (FBG) ≥ 126 mg/dL (7.0 mmol/L) were selected.
View details →Negative / Null Result ReportOpen accessDentistry
Gustavo Vicentis De Oliveira Fernandes, Nuno Bernardo Malta Santos, Rafael Amorim Cavalcanti De Siqueira et al. · 2021 · Journal of Indian Society of Periodontology
Background: Autologous platelet concentrate (APC)/platelet-rich fibrin (PRF) of second and third generations has increased use in periodontics to optimize wound healing. Few systematic reviews (SRs) have reported improved clinical outcomes, while other studies reported significantly better results for the connective tissue graft (CTG). There is still unclear clinical evidence about APC/PRF use to treat gingival recession (GR) defects. Then, the purpose of this SR was to evaluate the use of APC/PRF membranes (2nd and 3rd generations) in root coverage (RC) procedures and assess its efficacy as a
View details →Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Chiu Rossa WK, Chim Stephen SC, Wu Alan KL et al. · 2005 · BMC Infectious Diseases
Abstract Background It has been postulated that genetic predisposition may influence the susceptibility to SARS-coronavirus infection and disease outcomes. A recent study has suggested that the deletion allele (D allele) of the angiotensin converting enzyme ( ACE ) gene is associated with hypoxemia in SARS patients. Moreover, the ACE D allele has been shown to be more prevalent in patients suffering from adult respiratory distress syndrome (ARDS) in a previous study. Thus, we have investigated the association between ACE insertion/deletion (I/D) polymorphism and the progression to ARDS or requ
View details →Negative / Null Result ReportOpen accessMedicine
Seyed Jalal Hashemi, Hamidreza Shetabi, Shayan Saki et al. · 2018 · مجله دانشکده پزشکی اصفهان
Background: The purpose of this study was to compare the effect of endotracheal intubation in three methods of oral, and nasal with and without the help of Magill forceps, on heart rate and blood pressure in patients undergoing maxillofacial surgery. Methods: In this single-blind randomized clinical trial study, 96 patients who underwent facial and maxillofacial surgery, were randomly divided into three groups of oral, and nasal (with or without the use of Magill forceps) endotracheal intubation. Heart rate and blood pressure were studied in patients before the intubation, and 0, 1, 2, 5, and
View details →Negative / Null Result ReportOpen accessDentistry
Alireza Eshghi, Maryam Hajiahmadi, Mohammad Hossein Nikbakht et al. · 2022 · International Journal of Dentistry
Introduction. Among the new therapeutic materials, MTA and Biodentine are recommended for pulpotomy and sealing the pulp. Considering the similar characteristics of these two materials and considering that their effects on the treatment of primary second molars with irreversible pulpitis have not been compared properly, this study aimed to compare clinical and radiographic success between MTA and Biodentine in pulpotomy of primary mandibular second molars with irreversible pulpitis. Materials and Methods. This study was conducted as a randomized double-blind clinical trial. Participants were s
View details →Negative / Null Result ReportOpen accessAgriculture (General)
Jinglei Zhang, Shanshan Bai, Chunlin Jia et al. · 2025 · Agriculture
Agricultural expansion and intensification generally lead to a depletion in soil organic carbon (SOC). While converting cropland to grassland is a recognized strategy for SOC accumulation, the patterns of SOC accumulation under different grassland types and soil conditions remain unclear. This study evaluated the long-term effects of two perennial grasses—alfalfa (a legume) and switchgrass (a non-legume)—on SOC composition, specifically lignin phenols and amino sugars, in non-saline and saline–alkali soils, using a conventional wheat–maize rotation as a control. Our results showed that both al
View details →Negative / Null Result ReportOpen accessAnimal culture
Yosua Kristian Adi, Rini Widayanti, Tri Wahyu Pangestiningsih · 2018 · Veterinary World
Aim: n-Propanol extracts from fresh, boiled, and fermented seeds were studied to evaluate their neuroprotective effects in a Parkinson's disease (PD) rat model, based on the total number of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). Materials and Methods: Rats were induced with paraquat dichloride at a dosage of 7 mg/kg BW intraperitoneally twice a week and at the same time supplemented with extract at a dosage of 70 mg/kg BW orally every day for 3 weeks. On the 24th day, all rats were perfused and fixed with 4% paraformaldehyde. The left part of the SNpc was proce
View details →Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Arin Wulansari, Fryta Ameilia Luthfinnisa, Fuadah Uyun et al. · 2020 · Jurnal Gizi Indonesia: The Indonesian Journal of Nutrition
Background: Obesity cause various physiological changes in the body, one of which is insulin resistance causes high blood glucose levels. Chewing is a stimulus of cephalic phase responses and sensory stimulation that can increase hormones releasing such as insulin, ghrelin, cholecystokinin (CCK) and glucagon like peptide-1 (GLP-1). Chewing plays important role in determining postprandial plasma glucose concentration. Objective: Investigate the effect of chewing on postprandial blood glucose in obese adults. Method: This was true experimental research. Research subjects were treated in the form
View details →Negative / Null Result ReportOpen accessOphthalmology
Rini Saha, Gautam Singh Parmar, Ashok Kumar et al. · 2018 · Journal of Clinical Ophthalmology and Research
The aim of this study is to see the effect of transportation on corneoscleral buttons and to correlate them with the weight of ice used during transportation. This is a prospective cross-sectional study. A total of 119 corneas were graded using slit-lamp examination and specular microscopy before and after transportation. Groups were made based on the weight of ice used during transportation and the number of hours of storage in McCarey-Kaufman (MK) media. The overall median percentage of endothelial cell loss (ECL) was 11.33%. The median percentage of ECL was significantly more with <500 g of
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Jun Hamano, Masanori Mori, Taketoshi Ozawa et al. · 2021 · Cancer Medicine
Abstract Background Hyperactive delirium is known to increase family distress and the burden on health care providers. We compared the prevalence and associated factors of agitated delirium in advanced cancer patients between inpatient palliative care and palliative home care on admission and at 3 days before death. Methods This was a post hoc exploratory analysis of two multicenter, prospective cohort studies of advanced cancer patients, which were performed at 23 palliative care units (PCUs) between Jan and Dec 2017, and on 45 palliative home care services between July and Dec 2017. Results
View details →Negative / Null Result ReportOpen accessEnvironmental sciences
Dayong Zhao, Xinyi Cao, Jin Zeng et al. · 2017 · Journal of Freshwater Ecology
In order to investigate the effects of macrobenthos on the abundance and community composition of ammonia-oxidizing prokaryotes under different temperature conditions, laboratory microcosms containing two kinds of macrobenthos (Corbicula fluminea and Tubificid worms) were constructed. Real-time polymerase chain reaction (PCR) and clone libraries were applied to analyze the ammonia-oxidizing archaea (AOA) and bacteria (AOB) communities in the surface sediments. The lowest abundances of the archaeal and bacterial amoA gene were found in the samples cultured under 28 °C (archaeal amoA gene abunda
View details →Negative / Null Result ReportOpen accessMedicine
Erkal Bilgiç, Orhan Balta, Mehmet Burtaç Eren et al. · 2021 · Journal of Contemporary Medicine
Predictive scoring systems are designed to predict patients' discharge status, patient mortality, Intensive Care Unit(ICU) mortality and lenght of hospital stay. These scoring systems, which are aimed to standardize and form a common language in terms of evaluating patient general health situation, are used in the evaluation of patients in many ICU.In this study, we aimed to evaluate the ability of the scoring systems that can be used to predict the mortality of the patients who will be followed up in the ICU after orthopedic surgery and predict the mortality that occurs in the first year outs
View details →Negative / Null Result ReportOpen accessSurgery
Fei Wang, Xiaohui Niu, Haibo Xia et al. · 2024 · Frontiers in Surgery
PurposeTo compare the effect of two internal fixation methods of calcaneal plate fixation and Philos plate fixation in treating split fractures of humeral greater tuberosity.Patients and methodsA total of 37 patients with split fractures of humeral greater tuberosity were retrospectively analyzed from September 2016 to April 2021. Enrolled patients were divided into Group A (calcaneal anatomical locking plates), and Group B [Proximal Humeral Internal Locking System (PHILOS)]. The demographics, injury-related variables, surgery-related variables, Constant-Murley score, and postoperative complic
View details →Negative / Null Result ReportOpen accessMedicine
Mohammadreza Zarei, Mozhgan joker, Negin Larti et al. · 2020 · مجله دانشکده پزشکی اصفهان
Background: This study aimed to investigate and compare the characteristics of abdominal pain after bariatric surgery with two techniques of Laparoscopic One-Anastomosis Gastric Bypass (LOAGB) and Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) in patients with morbid obesity. Methods: This prospective descriptive-analytical study was conducted on 114 patients who were candidates for bariatric surgery. Patients were entered to study in one of two groups of LOAGB and LRYGB by convenient and continuous sampling. The characteristics of abdominal pain of patients were investigated and compared at ce
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Yoshiyasu Kono, Seiji Kawano, Yuki Okamoto et al. · 2018 · Therapeutic Advances in Gastroenterology
Background: The clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) during antithrombotic drug therapy has not been fully investigated. Methods: Patients who underwent video capsule endoscopy (VCE) for the investigation of OGIB at Okayama University Hospital from January 2009 to March 2016 were enrolled. We evaluated the VCE findings, the patterns of OGIB, and the rate of rebleeding within 1 year in antithrombotic drug users and antithrombotic drug nonusers. Results: A total of 181 patients were enrolled. Among the antithrombotic drug users, the rate of VCE positivity in
View details →Negative / Null Result ReportOpen accessAquaculture. Fisheries. Angling
S. Dalal, S. Bhattacharya, A.K. Ray · 2001 · Acta Ichthyologica et Piscatoria
A 60-day feeding experiment was conducted in the laboratory to evaluate the interactive effects of dietary protein and carbohydrate levels on growth, feed utilization efficiency, and nitrogen metabolism in rohu, Labeo rohita fingerlings (mean weight 4.06 ±0.08 g). Nine purified diets prepared with 25, 35, and 40 % protein level each having 15, 25, and 35 % carbohydrate were fed to nine different feeding groups at the rate of 3% of body weight in triplicate treatments. Better performance of fish in terms of percent weight gain, SGR, FCR, and PER was observed with increasing percentage of
View details →Negative / Null Result ReportOpen accessMedicine (General)
Nahid Jashirenezhad, Sahar Almasi Turk, Marzieh Mahmoodi et al. · 2025 · Iranian South Medical Journal
Background: Identifying individuals based on their height is of great importance, especially in cases such as accidents or burns where identifying individuals is challenging. Therefore, the aim of this study was to investigate upper extremity parameters in a population of Bushehr in a relative formulation to predict their stature using anatomical indices. Materials and Methods: The project involved men and women aged 18 to 50 who were themselves born and both they and two generations before them also lived there. The indices of arm, forearm, hand, upper extremity, and stature were measured in
View details →Negative / Null Result ReportOpen accessBiology (General)
Kevin Hoffseth, Emily Busse, Josue Jaramillo et al. · 2021 · Frontiers in Cell and Developmental Biology
Mouse digit amputation provides a useful model of bone growth after injury, in that the injury promotes intramembranous bone formation in an adult animal. The digit tip is composed of skin, nerves, blood vessels, bones, and tendons, all of which regenerate after digit tip amputation, making it a powerful model for multi-tissue regeneration. Bone integrity relies upon a balanced remodeling between bone resorption and formation, which, when disrupted, results in changes to bone architecture and biomechanics, particularly during aging. In this study, we used recently developed techniques to evalu
View details →Negative / Null Result ReportOpen accessDentistry
Fatemeh Ezoddini Ardakani, Vahid Sarayesh · 2008 · Journal of Dental Research, Dental Clinics, Dental Prospects
Background and aims. While the use of X-ray is increasing, professional responsibility of dentists entitles them to have sufficient and correct knowledge of using radiographs. The aim of this study was to assess the level of knowledge of correct prescription of radiographs among dentists in Yazd, Iran. Materials and methods. This was a descriptive cross-sectional study including 134 general dentists and dental specialists. A self-administered questionnaire was used to assess their level of knowledge in various sections pertaining to prescription of radiographs. Their level of knowledge was com
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