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Browse the failure-mode index

19,878 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Impact of chronic kidney disease on clinical outcomes among patients with atrial fibrillation following percutaneous left atrial appendage occlusion: a multicentre cohort study.

Amin, Awashra, Khan et al. · 2026 · European heart journal open

Atrial fibrillation (AF) and chronic kidney disease (CKD) often coexist, and both increase the risk of thromboembolism and bleeding. We aim to investigate the impact of CKD in patients with AF undergoing left atrial appendage occlusion…

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Negative / Null Result ReportMedicine

Effect of Implant Design on Fracture Resistance, Mode, and Crystal Structure of One- and Two-Piece Zirconia Implants With Ceramic or Titanium Abutment Screws: An In Vitro Study.

Gul, Papia, Eqtesadi et al. · 2026 · Clinical oral implants research

To evaluate the fracture resistance, fracture modes, and crystalline phase changes of zirconia one-piece implants (OPI) and bone-level (BLTPI) or tissue-level, two-piece implants (TLTPI), with ceramic (C) or titanium (T) abutment screws…

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Negative / Null Result ReportMedicine

Effect of Visceral Manipulation Versus Integrated Neuromuscular Inhibition Technique in Shoulder Impingement Syndrome.

Elserty, Shokry, Altoury et al. · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Shoulder pain during daily activities is a common musculoskeletal complaint affecting individuals across all age groups. Among its causes, Shoulder Impingement Syndrome (SIS) is one of the most prevalent. This study aimed to compare the…

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Negative / Null Result ReportMedicine

Outcome-driven dosimetry optimization for [ 177 Lu]Lu-PSMA-617 radiopharmaceutical therapy: proof of concept on single time point dosimetry optimization.

Hu, Seifert, Gomes et al. · 2026 · European journal of nuclear medicine and molecular imaging

Internal dosimetry in radiopharmaceutical therapy (RPT) traditionally prioritizes methodological optimization driven by physical dose accuracy. However, even recommended multiple-time-point (MTP) dosimetry remains subject to uncertainties…

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Negative / Null Result ReportMedicine

Non-tobacco nicotine use and complications in single-level posterior lumbar and transforaminal lumbar interbody fusion.

Nguyen, Hall, Lebens et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Over 300,000 lumbar fusion surgeries are performed annually for various indications. Tobacco use has previously been demonstrated to increase rates of nonunion and mechanical complications, but the impact of non-tobacco nicotine (NTN)…

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Negative / Null Result ReportMedicine

Effects of Oxidative Stress and Antioxidant Activity in Uterine Flush Fluid During Early Postpartum on Reproductive Performance of Lactating Holstein-Friesian Dairy Cows.

Hagita, Miura, Shirasuna et al. · 2026 · Animal science journal = Nihon chikusan Gakkaiho

This study examined the impact of early postpartum uterine oxidative stress and antioxidant activity on subsequent reproductive performance in lactating Holstein-Friesian dairy cows. Uterine flush fluid samples were collected at…

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Negative / Null Result ReportMedicine

Inhaled corticosteroids monotherapy in childhood asthma: Any differential response rate between activated and prodrugs?

Majumder, Smyrnova, Ducharme · 2026 · The Journal of asthma : official journal of the Association for the Care of Asthma

The efficacy of inhaled corticosteroids (ICS) as prodrugs (inactive at delivery) has been compared to activated ICS, in mean changes in lung function and symptoms, with limited evidence on achieving control. We aimed to compare the…

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Negative / Null Result ReportMedicine

Arthroscopic Repair of Anterior Labroligamentous Periosteal Sleeve Avulsion Lesions Achieves Similar Outcomes and Labral Height Compared With Typical Bankart Lesions With Adequate Capsulolabral Release.

Chang, Lee, Yoon et al. · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

To compare the serial measurements of repaired labral height in the early and late postoperative periods and clinical outcomes between patients with Bankart lesions and those with anterior labroligamentous periosteal sleeve avulsion…

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Negative / Null Result ReportMedicine

Oral Health Status and Utilization of Dental Services Among Adults With Disability Compared to Those Without Disabilities in Nevada, United States.

Benson, Gomez, DerAshodian et al. · 2026 · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

This study examines disability-related disparities in tooth loss and dental visits, and Medicaid dental service utilization across Nevada counties in 2022. A cross-sectional analysis of the 2022 Behavioral Risk Factor Surveillance System…

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Negative / Null Result ReportMedicine

Consensus-Level and Cluster-Adjusted Evaluation of a Large Language Model for Diagnostic Extraction from Musculoskeletal Radiology Reports.

Bosbach, Montazeri, Senge et al. · 2026 · Diagnostics (Basel, Switzerland)

Purpose: Large language models (LLMs) may reduce administrative workload in radiology by automating structured diagnostic extraction from text reports. This study evaluates the accuracy of ChatGPT-4.0 when extracting correct diagnoses from…

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Negative / Null Result ReportMedicine

Impact of Body Mass Index on Clinical Outcomes of LLETZ.

Paternostro, Joura, Postl et al. · 2026 · Journal of clinical medicine

Background/Objectives: Large loop excision of the transformation zone (LLETZ) is used as a standard treatment for cervical dysplasia. Although obesity is associated with reduced cervical screening participation and may complicate…

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Negative / Null Result ReportMedicine

Outcomes of Indication-Based Reconstruction Strategies in a Retrospective Observational Cohort of Patients with Paprosky Type IIC Acetabular Defects.

Astan, Balta, Zengin et al. · 2026 · Journal of clinical medicine

Background/Objectives: Paprosky Type IIC acetabular defects encountered during revision total hip arthroplasty (rTHA) present substantial challenges in terms of surgical planning and implant stability. This study evaluates the outcomes of…

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