20,240 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Shi X, Motevalli S, Chang EJY et al. · 2026 · Preprint
Background: Anxiety and obesity can have negative impacts on the health of children. Understanding the relationship between obesity and mental disorders in children and adolescents will help develop effective prevention and intervention…
View details →Couturier I, Denis S, Rossary A et al. · 2026 · Food chemistry
Cooked High Amylose Wheat (HAW) products are dietary sources of resistant starch (RS). While its effects on gut microbiota are known, links to immune responses remain unclear. This study evaluated the antioxidant and anti-inflammatory…
View details →Płuciennik K, Bukowska B, Sicińska P · 2026 · Nanotoxicology
The widespread presence of polystyrene nanoparticles (PS-NPs) in the human body has raised concerns about their potential biological toxicity. When assessing the safety of nanoparticles and other xenobiotics, a key aspect is their effect…
View details →Liu W, Tang Y, Ding W et al. · 2026 · Preprint
Purpose: Estrogen deficiency drives bone loss through a complex interplay of endocrine, oxidative, inflammatory, and bone-remodeling disturbances. Ergothioneine (EGT) is a diet-derived thiol/thione antioxidant, yet its effects on the…
View details →Hoshiyama K, Hirano T, Sekiya E et al. · 2026 · Scientific reports
This prospective observational study evaluated short-term intraocular pressure (IOP) changes and safety following intravitreal injection of aflibercept 8 mg versus 2 mg in diabetic macular edema (DME). We included 40 eyes from 36 patients…
View details →Bektaş B, Ulusoy CO, Uslu H et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Objective In the present study, we aimed to evaluate the impact of vaginal birth after cesarean (VBAC) on quality of life, sexual function, sleep quality, and urinary incontinence and compare the results with those of vaginal birth (VB)…
View details →Avalos MA, Shah S, Rosenblatt NJ · 2026 · Experimental brain research
Following a loss of balance, proper reactive responses are needed to avoid a fall. Efforts have focused on how physiological factors affect these responses, but few have addressed psychological states. One psychological factor of…
View details →Burgazli AY, Avuloglu Yilmaz E, Mamur S et al. · 2026 · Toxicology mechanisms and methods
Hyperoside (HYP), a plant-derived flavonoid, was evaluated for its cytotoxic, anti-cancer, genotoxic, antigenotoxic, and antioxidant properties, and potential mechanisms of action using an integrated in vitro and in silico approach.…
View details →Wu Y, Zhu L, Lin G et al. · 2026 · Bioresource technology
Antibiotic resistance genes (ARGs) are an increasing environmental and public health concern in wastewater treatment systems due to their persistence, mobility, and links to human bacterial pathogens (HBPs). In this study, aerobic…
View details →Li H, Zhao B, Wang J et al. · 2026 · Theriogenology
Ovum pick-up and in vitro embryo production (OPU-IVP) in Holstein cows is influenced by donor characteristics, yet quantitative selection criteria for optimizing oocyte developmental competence remain limited. In this study, data from 600…
View details →Vukovic V, Karan-Djurasevic T, Antic D et al. · 2026 · Biomolecules & biomedicine
Fludarabine treatment in patients with chronic lymphocytic leukemia (CLL) has been associated with immune dysregulation and the development of autoimmune hemolytic anemia (AIHA). Prior research indicates a potential correlation between the…
View details →Gutierrez AM, Robinson JO, Allen-Rhoades WA et al. · 2026 · Pediatric blood & cancer
Background Decision-making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and…
View details →Ahmed ME, Mahjoub SMAH, Adam SIY · 2026 · Tropical animal health and production
This study evaluated the effects of partially replacing groundnut cake with soaked chickpea (Cicer arietinum L.) seeds, with or without enzyme supplementation, on growth performance, carcass traits, serum biochemical indices, and…
View details →Ren X, Wu Q, Zhao M et al. · 2026 · Preprint
This research aimed to determine the effects of replacing ryegrass (Lolium perenne L.) with licorice residue (LR) on growth performance, slaughtering performance, meat quality, serum biochemistry and cecal flora. Five pelleted rations were…
View details →Uğurlu T, Sağlam BC, Koçak S et al. · 2026 · Preprint
Abstract Background The aim of this in vitro study was to examine the effects of different glide path files on root canal transportation and centering in curved root canals. Methods In this study, 33 mandibular first molars with a 10 mm…
View details →Alqantash AH, Alshehri SM, Almalki AA et al. · 2026 · Preprint
Abstract Background Medical students, as future healthcare providers, must possess a comprehensive understanding of medication safety during pregnancy to prevent teratogenic risks and ensure maternal health. Knowledge gaps in this area can…
View details →Thapa K, R Iyer A, A Cruz-Gonzalez M et al. · 2026 · Journal of racial and ethnic health disparities
Background Refugees often experience disruptions in social networks after resettlement. This study examined associations between bonding (within-group) and bridging (across-group) social capital and self-rated health among resettled U.S.…
View details →Kozakoğlu F, Gürses M · 2026 · Preprint
Abstract Objectives: This study aimed to evaluate the 1-year clinical performance of Ribbond-reinforced direct composite restorations placed in different orientations in endodontically treated posterior teeth. Materials and Methods: This…
View details →Mathiesen KK, Rasmussen JH, Channir H et al. · 2026 · Acta oto-laryngologica
Background Cancer of unknown primary (CUP) is diagnostically challenging. Diagnostic strategy remains controversial. Aim The aim of this retrospective study was to evaluate the diagnostic value of FDG-PET/CT and MRI in detecting primary…
View details →Vega MM, Roberts MD, Goble DJ et al. · 2026 · Preprint
Abstract Background Aging is associated with increases in fat mass (FM) and decreases in fat-free mass (FFM), yet whether these indices independently predict force plate-derived postural sway and low-frequency postural oscillations remains…
View details →Abdulameer HS, Zarrinkavyani K, Fathi M et al. · 2026 · Poultry science
Transport of day-old chicks is a major concern in the poultry industry, as it induces stress that can impair performance and health. This study investigated whether xylazine, an alpha-2 adrenergic agonist that reduces metabolic rate, could…
View details →Rutkūnas V, Kubilius A, Akulauskas M et al. · 2026 · Journal of dentistry
Objectives This in vitro study evaluated the accuracy of digital impressions for full-arch implantsupported restorations by assessing scan body (SB) positional accuracy and inter-arch registration under different intraoral scanners (IOS)…
View details →Østergaard AM, Rosenbæk JB, Ejlersen JA et al. · 2026 · Physiological reports
Inorganic nitrate may lower blood pressure (BP) and enhance natriuresis through nitric oxide (NO) mediated mechanisms. Studies have found inconsistent effects of NO on sodium excretion. Nitric oxide synthase (NOS) inhibition suggests…
View details →Phan T, Datt P, Zhao L et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Purpose Rheumatoid arthritis (RA) is a chronic, autoimmune joint disorder necessitating the use of complex, specialty medications. Health-system specialty pharmacies (HSSPs) operate under closed-loop models that have been shown to minimize…
View details →Júnior FC, Santos WRD, Cordeiro Feitosa R et al. · 2026 · Research quarterly for exercise and sport
Taurine (TAU) is a conditionally essential amino acid whose consumption has recently increased, particularly among young people, through supplements and energy drinks. It has potential beneficial effects on physical performance; however,…
View details →Haskic A, Hadziabdic N, Miron RJ · 2026 · International journal of oral and maxillofacial surgery
Postoperative sequelae such as pain, swelling, and trismus are common following mandibular third molar surgery. This single-blind controlled trial was performed to evaluate the effects of two newer platelet-rich fibrin (PRF) formulations,…
View details →Choo LY, Zheng W, Wen S et al. · 2026 · Journal of the American Pharmacists Association : JAPhA
Background Patients with opioid use disorder encounter challenges obtaining buprenorphine (BUP) at pharmacies, increasing their risk of treatment non-adherence and illicit drug use. Objectives The purpose of this quality improvement (QI)…
View details →DiBona ER, Elliott J, Labeille RO et al. · 2026 · Aquatic toxicology (Amsterdam, Netherlands)
Per- and polyfluoroalkyl substances (PFAS) are persistent contaminants with immunotoxic potential, yet impacts on immune development remain poorly defined. We examined effects of developmental PFAS exposure on host resistance and…
View details →Gok A, Kavakli AS, Sugur T et al. · 2026 · Expert review of anti-infective therapy
Background This study aimed to assess culture positivity rates and the microbiological profile of intensive care unit (ICU)-acquired superinfections in patients with severe COVID-19 pneumonia treated with pulse-dose methylprednisolone,…
View details →Neff J, Ektnitphong VA, Campos PC et al. · 2026 · Preprint
Host cell metabolic pathways influence innate immune responses to intracellular pathogens, but the contribution of nucleotide metabolism to antimicrobial defense remains incompletely defined. Here, we identify the mitochondrial nucleoside…
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