Negative / Null Result ReportOpen accessMedicine (General)
Rui Ping Peng, Zi Qian Zhu, Hong Yi Shen et al. · 2022 · Frontiers in Medicine
ObjectiveThis study aimed to observe vascular and neuroretinal alterations in people with prediabetes [impaired fasting glucose (IFG) and impaired glucose tolerance (IGT)] and normal glucose metabolism.MethodsA total of 21 patients with prediabetes (42 eyes) and 20 healthy controls (40 eyes) participated in our study. All patients underwent a complete eye examination [including fundus fluorescein angiography (FFA) and optical coherence tomography (OCT)] and a related general examination (complete biochemical analysis, routine blood tests, and glycosylated hemoglobin).ResultsOn FFA, no patients
View details →Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
Alexandra Skovran, Mason Hinke, Shelly N. B. Sloan et al. · 2022 · Emergency and Critical Care Medicine
Abstract. Background. Sepsis is the leading cause of death in hospitalized patients and significant effort has been made to facilitate early diagnosis and management. However, aggressive treatment can have negative effects, especially in patients with unstable volume status, such as those with congestive heart failure. Methods. We used electronic medical records to perform a retrospective study looking at hospital outcomes in patients from Southwest Missouri who were admitted with sepsis and had a comorbid diagnosis of hypertensive heart failure. Our primary outcome was in-hospital mortality.
View details →Negative / Null Result ReportOpen accessDentistry
Utku Böcüoğlu, Esra Ateş Yıldırım, Selma Erdoğan Düzcü et al. · 2026 · BMC Oral Health
Abstract Objectives This in vitro study aimed to evaluate the effect of laser photobiomodulation on the structural integrity and degradation resistance of two types of platelet-rich fibrin membranes: Leukocyte- and Platelet-Rich Fibrin (L-PRF) and Titanium-Prepared Platelet-Rich Fibrin (T-PRF). Structural changes in the fibrin network were assessed using Scanning Electron Microscopy (SEM) and light microscopy. Materials and methods Our study was performed on 15 systemically healthy individuals and four L-PRF and four T-PRF membranes obtained from each individual, totaling 120 samples. L-PRF wa
View details →Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Zhu Guo-Pei, Lu Jiade, Xiong Xiao-Peng et al. · 2011 · Radiation Oncology
Abstract Background High-precision radiation therapy techniques such as IMRT or sterotactic radiosurgery, delivers more complex treatment fields than conventional techniques. The increased complexity causes longer dose delivery times for each fraction. The purpose of this work is to explore the radiobiologic effect of prolonged fraction delivery time on tumor response and survival in vivo. Methods 1-cm-diameter Lewis lung cancer tumors growing in the legs of C57BL mice were used. To evaluate effect of dose delivery prolongation, 18 Gy was divided into different subfractions. 48 mice were rando
View details →Negative / Null Result ReportOpen accessSurgery
Eiji Nomura, Takatoshi Seki, Kentaro Yatabe et al. · 2024 · World Journal of Surgical Oncology
Abstract Background Elderly gastric cancer patients (EGCPs) require treatment according to not just the stage of their cancer, but also to their general condition and organ function, and rather than full treatment, the appropriate amount of treatment is necessary. Methods A total of 425 patients who underwent gastrectomy for primary gastric cancer in our institution between April 2013 and March 2020 were classified by age into two groups: elderly patients (EP, age ≥ 80 years, n = 89); and younger patients (YP, age < 80 years, n = 336). The preoperative, intraoperative, and postoperative condit
View details →Negative / Null Result ReportOpen accessMedicine
Falcão MG, Suarez MA, Ferreira ACOP et al. · 2026 · Acta ortopedica brasileira
Objective To analyze the outcomes related to partial and total hip arthroplasties in elderly patients with femoral neck fractures at a hospital in the city of São Paulo. Material and methods We reviewed the medical records of patients…
View details →Negative / Null Result ReportOpen accessDentistry
Muhammad Zubair Ahmad · 2024 · International Journal of Dentistry
Objectives. Rotary single-file endodontic systems are commonly used for root canal treatment. However, very few studies have evaluated the apical extrusion of debris generated by these systems during canal preparation at normal body temperature in laboratory conditions. The aim of this study was to evaluate the amount of apically extruded debris caused by seven different single-file endodontic instrumentation systems at body temperature in mandibular molar teeth with curved root canals. Methods. One hundred forty mandibular first permanent molars were randomly divided into seven groups (n = 20
View details →Negative / Null Result ReportOpen accessBiotechnology
Cai Wang, Cai Wang, Dongyuan Xin et al. · 2023 · Frontiers in Bioengineering and Biotechnology
Introduction: Interleukin-6 (IL-6) is a multifunctional polypeptide cytokine composed of two glycoprotein chains, which plays an important role in many cellular reactions, pathological processes, diagnosis and treatment of diseases and so on. The detection of IL-6 plays a promising role in the cognition of clinical diseases.Methods: 4-mercaptobenzoic acid (4-MBA) was immobilized on the gold nanoparticles modified platinum carbon (PC) electrode with the linker IL-6 antibody, and finally formed an electrochemical sensor that specifically recognized IL-6. Through the highly specific antigen-antib
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Olga Maria Nardone, Giulio Calabrese, Alessia La Mantia et al. · 2025 · Therapeutic Advances in Gastroenterology
Background: Managing extraintestinal manifestations (EIMs) in inflammatory bowel disease (IBD) patients remains challenging due to considerable heterogeneity in diagnostic criteria and the lack of a standardised definition and validated diagnostic pathways. Delays in recognising and treating EIMs can lead to significant disease progression. Therefore, early detection and treatment are crucial. Objectives: We aimed to assess the effectiveness of a dedicated immune-mediated inflammatory diseases (IMIDs) clinic in reducing EIM diagnostic delays and improving patients’ outcomes. Design: A single-c
View details →Negative / Null Result ReportOpen accessMedicine
Qina Ye, Shaodan Sun, Jian Deng et al. · 2023 · Scientific Reports
Abstract To investigate the gut microbiota distribution and its functions in children with avoidant/restrictive food intake disorder (ARFID). A total of 135 children were enrolled in the study, including 102 children with ARFID and 33 healthy children. Fecal samples were analyzed to explore differences in gut microbiota composition and diversity and functional differences between the ARFID and healthy control (HC) groups via 16S rDNA and metagenomic sequencing. The gut microbiota composition and diversity in children with ARFID were different from those in heathy children, but there is no diff
View details →Negative / Null Result ReportOpen accessAnimal culture
R. Shi, D. Liu, J. Sun et al. · 2015 · Czech Journal of Animal Science
Iron (Fe) is an essential mineral for animal development and function. The present study was carried out to evaluate the effect of replacing FeSO4 with iron glycine chelate (Fe-Gly) in the equal Fe level in diets on broiler chickens. The broilers were randomly allotted to 6 dietary treatments with 5 replicate pens and 10 birds per pen. The treatments consisted of: Control group (100 mg Fe from FeSO4/kg diet), Experimental group 1 (80 mg Fe from FeSO4 + 20 mg Fe from Fe-Gly/kg diet), Experimental group 2 (60 mg Fe from FeSO4 + 40 mg Fe from Fe-Gly/kg diet), Experimental group 3 (40 mg Fe from F
View details →Negative / Null Result ReportOpen accessBanking
Suripto, Arif Sugiono, Havid Dasuki · 2023 · Banks and Bank Systems
This study aims to analyze the comparison of the resilience of Islamic and conventional banking in the Association of Southeast Asian Nations (ASEAN) during the COVID-19 pandemic. Comparison of banking resilience was proxied by the Capital Adequacy Ratio (CAR) and Loan-to-Deposit Ratio (LDR) factors, Return on Assets (ROA) and Non-Performing Loans (NPL) with the Multiple Discriminant Analysis test. In this case, the emphasis is placed on the patterns by which Islamic and conventional banking in ASEAN weathered the recent financial crisis during the COVID-19 pandemic. The explanatory and quanti
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Davies Isabel R, Gavrilovic Jelena, Baugh Mark D et al. · 2003 · Cardiovascular Diabetology
Abstract Background Coronary plaque rupture may result from localised over expression of matrix metalloproteinases (MMPs) within the plaque by infiltrating monocyte – macrophages. As MMP expression can be promoted by the modified lipoproteins, oxidative stress and hyperglycaemia that characterises Type 2 diabetes, we hypothesised that peripheral monocytes in these patients, exposed to these factors in vivo, would demonstrate increased MMP production compared to controls. Methods We examined peripheral venous monocyte expression of MMP and tissue inhibitor of metalloproteinase-1 (TIMP-1) in 18
View details →Negative / Null Result ReportOpen accessMedicine (General)
F Ansari, L Akbari, SH Kohan · 2021 · Armaghane Danesh Bimonthly Journal
Background & aim: Background and Aim: Among working women, health professionals are more exposed to environmental factors and unfavorable working conditions than working women. A large group of health professionals consists of nurses and operating room staff who provide services in hospitals. For this purpose, the present study was conducted to determine the effect of unfavorable working conditions on the incidence of spontaneous abortion in operating room staff and nurses of teaching hospitals in Isfahan. Methods: This was a retrospective analytical study. The statistical population included
View details →Negative / Null Result ReportOpen accessSurgery
Nguyen Tai Thu, Pham Dang Hai, Nguyen Thi Kieu Ly et al. · 2024 · Egyptian Liver Journal
Abstract Background Cirrhosis is associated with chronic cardiovascular dysfunction termed cirrhotic cardiomyopathy (CCM), characterized by myocardial hypertrophy and diastolic dysfunction. Detecting early cardiac changes is crucial, especially in patients undergoing liver transplantation. Objective: This study aims to evaluate left ventricular systolic function in cirrhotic patients undergoing liver transplantation using speckle-tracking echocardiography. Methods A prospective observational study was conducted involving 54 cirrhotic patients who underwent liver transplantation, along with 28
View details →Negative / Null Result ReportOpen accessPediatrics
Mohaddeseh Badpeyma, Roghayeh Molani-Gol, Fatemeh Sistanian et al. · 2024 · Iranian Journal of Neonatology
Background: This study aims to determine the effect of different GnRH agonist brands on body mass index (BMI), weight, and height in patients referred to the pediatric endocrinology clinic of Akbar Hospital.Methods: In this cohort study, 80 girls aged 5-8 years diagnosed with precocious puberty cases were included according to the Tanner staging and at the second puberty stage. The patients were classified into three groups of GnRH agonists, A, B, and C, receiving Diphereline, Microrelin, and Variopeptyl, respectively. Height, weight, and BMI were calculated every three months.Results: In grou
View details →Negative / Null Result ReportOpen accessDentistry
Sara Jafarimofrad, Hamid Sarlak, Shima Nourmohammadi · 2022 · Dental Research Journal
Background: Control of pain, fear, and anxiety of pediatric dental patients is a common concern for the parents and dental clinicians. This study aimed to compare the efficacy of audiovisual distraction (AVD) and mute-video distraction (MVD) for reduction of pain and anxiety of pediatric dental patients. Materials and Methods: This randomized split-mouth crossover clinical trial evaluated 60 systemically healthy children between 4 and 7 years requiring bilateral pulpotomy of primary maxillary first molars. The samples were randomly divided into 6 groups based on the distraction technique and s
View details →Negative / Null Result ReportOpen accessMedicine (General)
Osama Ragaa Abdelraouf, Amr Almaz Abdel-aziem · 2021 · Chinese Journal of Traumatology
Purpose: This study evaluated the angular kinematic and moment of the ankle and foot during shod walking and barefoot walking in individuals with unilateral chronic ankle instability (CAI). Methods: Recreational soccer players with unilateral CAI were recruited for this cross sectional study conducted between January and August 2019. A total of 40 participants were screened for eligibility but only 31 met the inclusion criteria based on the methods of Delahunt et al and Gribble et al. Except for 3 participants not attending the evaluation session, 28 participants were finally included. A three
View details →Negative / Null Result ReportOpen accessMedicine
Sabah Jalal Sherif, Baderkhan Saeed Ahmed, Botan Abdul Kadir Ali · 2023 · Advanced Medical Journal
Background and objective: Acute appendicitis is one of the most common surgical emergency con-ditions. This study was done to clarify the effect of antibiotics in reducing post appendectomy com- plications after open and laparoscopic appendectomy in patients with non-perforated appendicitis. Methods:This is a randomized controlled trial. Three hundred and twenty one patients, who underwent appendectomy for non-perforated appendicitis and fulfilled the selection criteria, were randomly divided into two groups. The patients in group A received double dose of pre-operative and postoperative antib
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Guozhong Wang, Quanming Zhao, Qing Cheng et al. · 2019 · BMC Cardiovascular Disorders
Abstract Background The rational length of stay following non-complicated percutaneous coronary intervention (PCI) for Non-ST elevation myocardial infarction (NSTEMI) patients remains controversial. Few studies have examined the impact of early discharge on short-term outcomes in NSTEMI patients, but short-time discharge is not uncommon in real world practice. This study examined the impact of short time discharge following non-complicated PCI on 30-day net adverse clinical events in NSTEMI patients. Methods This retrospective study enrolled 1424 consecutive patients with NSTEMI diagnoses who
View details →Negative / Null Result ReportOpen accessPlant culture
Qing Zhou, Qing Zhou, Qing Zhou et al. · 2020 · Frontiers in Plant Science
Triploid breeding is a central way to improve growth traits, timber quality, and stress resistance in Populus. In the present study, the morphology and viability of colchicine-induced 2n pollen, triploid production by crossing induced 2n pollen, and identification of genetic constitution of colchicine-induced 2n pollen were conducted in Populus canescens based on optimizing technology for inducing chromosome doubling in pollen. We found that the meiotic stage, injection time, and the interaction between the meiotic stage and injection time had highly significant effects on the 2n pollen produc
View details →Negative / Null Result ReportOpen accessDentistry
Azam Valian, Zahra Jaber Ansari, Mohammad Moien Rezaie et al. · 2021 · BMC Oral Health
Abstract Background Esthetic dental restorations have gained increasing popularity. The surface of restorations should be smooth enough to achieve maximum esthetics and prevent the adhesion of microorganisms and food particles. This study aimed to assess the surface roughness and color change of composite specimens following airflow usage. Methods In this in vitro, experimental study, 30 Tokuyama composite discs were fabricated and randomly divided into three groups (n = 10) for the use of airflow with calcium carbonate/bicarbonate powder and conventional polishing with FlexiDisc. The surface
View details →Negative / Null Result ReportOpen accessMedicine
Mustafa Umut Somuncu, Huseyin Karakurt · 2019 · Türk Kardiyoloji Derneği Arşivi
Objective: Primary prevention of sudden cardiac death in ST-elevation myocardial infarction (STEMI) is a complicated issue due to the highly heterogeneous population. The effect of T-wave alternans (TWA) on cardiac mortality has been examined in various populations, most often in patients with a high risk of fatal arrhythmia, such as patients with a low left ventricular ejection fraction (LVEF). The aim of the present study was to investigate the prevalence of TWA and its relationship to cardiac mortality in young STEMI patients with preserved LVEF. Methods: A total of 108 STEMI patients with
View details →Negative / Null Result ReportOpen accessMedicine (General)
Xu Xiaofeng, Zhan Linsen, Lu Huarong et al. · 2024 · Vojnosanitetski Pregled
Background/Aim. Since finding a safe and efficient strategy of multimodal postoperative analgesia and sedation is particularly critical, it is important that dexmedetomidine (DM) combined with opioid anesthetics can enhance that through a synergistic action. The aim of the study was to assess the effect of butorphanol tartrate (BT) combined with DM on postoperative analgesia. Methods. A total of 100 elderly patients undergoing general anesthesia surgery from January 2019 to June 2022 were selected. The patients were divided into two equal groups – research group (RG) and control group (CG), us
View details →Negative / Null Result ReportOpen accessDentistry
Mohamed Abo-El-Saad, Sherif Ayad, Lydia Melek et al. · 2023 · Alexandria Dental Journal
Background: After extracting teeth, both remarkable resorption in the alveolar bone and an obvious reduction have occurred in the labial bone plate as a consequence of the blood supply deficiency that happens especially when the periodontal ligaments are lost. Therefore, to keep the periodontal ligaments preserved, a socket shield technique with autogenous dentine was introduced.Aim of this study: Radiographic evaluation of a combined technique using autogenous dentin graft with socket shield for pre-implant socket preservationPatient and method: Eight patients received socket preservation usi
View details →Negative / Null Result ReportOpen accessOphthalmology
Jehan Fauzi Rakhmandani, Indra Tri Mahayana, Felicia Widyaputri et al. · 2023 · Taiwan Journal of Ophthalmology
PURPOSE: To assess the change of interleukin-6 (IL-6) levels in tears and ocular clinical parameters in corneal ulcer patients with moderate-to-severe infection after adjunctive therapy with platelet-rich fibrin (PRF) lysate-eyedrops compared with autologous serum eyedrops. MATERIALS AND METHODS: This study was a randomized double-blind controlled trial, which compared two groups of patients at Dr. Sardjito Hospital, Yogyakarta. A total of 42 patients (42 eyes) were divided into the control group (21 patients) and the intervention group (21 patients). All patients received antibacterial/antifu
View details →Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
Reza Azizkhani, Mehrdad Esmailian, Azadeh shojaei et al. · 2015 · Emergency
Introduction: Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ketamine in laceration repair. Therefore, the present study was aimed to comparison of induced sedation by rectal sodium thiopental and muscular injection of hydrochloride ketamine in pediatric patients need laceration repair. Methods: The presented study is a single-blinded clinical trial performed through 2013 to 2014 in Ayatollah Kashani and Alzahr
View details →Negative / Null Result ReportOpen accessMedicine
Yasser Rezapour, Kianoush Abdi, Hossein Rezai et al. · 2011 · Iranian Rehabilitation Journal
Objectives: The spontaneous language sample analysis is an important part of the language assessment protocol. Language samples give us useful information about how children use language in the natural situations of daily life. The purpose of this study was to compare Conversation, Freeplay, and narrative speech in aspects of Mean Length of Utterance (MLU), Type-token ratio (TTR), and the number of utterances. Methods: By cluster sampling method, a total of 30 Semnanian five-year-old boys with normal speech and language development were selected from the active kindergartens in Semnan city. Co
View details →Negative / Null Result ReportOpen accessAgriculture (General)
Junaid Mushtaq Lone, Shinsuke Agehara, Amr Abd-Elrahman · 2024 · Agricultural Water Management
Commercial strawberry (Fragaria ×ananassa Duch.) production in Florida relies heavily on bare-root transplants, which typically have 3–5 leaves with partially desiccated roots. Successful establishment requires sprinkler irrigation during daylight hours for the first 10–14 days, leading to substantial water consumption. To address this issue, we evaluated the efficacy of intermittent sprinkler irrigation as a water conservation strategy. We conducted field experiments over two growing seasons [Season 1 (2021–22) and Season 2 (2022–23)] in west-central Florida using three major strawberry culti
View details →Negative / Null Result ReportOpen accessFood processing and manufacture
Liming LIN, Qinfei WANG, Houmei YU et al. · 2022 · Shipin gongye ke-ji
In order to understand the freezing characteristics and metabolites of cassava root, the edible cassava variety “South China 9” was taken as the research object, by measuring the freezing-law and related influencing factors at the head, middle and tail of cassava root, combined with non-targeted metabolomics to analyze the differential metabolite. The results showed that: The freezing temperature was from −0.6 to −1.1 ℃ in different parts of root, but the freezing time was different. The highest values of soluble solid content and starch content in different parts appeared in the head, which w
View details →