The in vivo study on the radiobiologic effect of prolonged delivery time to tumor control in C57BL mice implanted with Lewis lung cancer
Zhu Guo-Pei; Lu Jiade; Xiong Xiao-Peng; Wang Xin; He Shao-Qin; Hu Chao-Su; Ying Hong-Mei · 2011 · Radiation Oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background High-precision radiation therapy techniques such as IMRT or sterotactic radiosurgery, delivers more complex treatment fields than conventional techniques. The increased complexity causes longer dose delivery times for each fraction. The purpose of this work is to explore the radiobiologic effect of prolonged fraction delivery time on tumor response and survival in vivo. Methods 1-cm-diameter Lewis lung cancer tumors growing in the legs of C57BL mice were used. To evaluate effect of dose delivery prolongation, 18 Gy was divided into different subfractions. 48 mice were rando
Abstract by Zhu Guo-Pei; Lu Jiade; Xiong Xiao-Peng; Wang Xin; He Shao-Qin; Hu Chao-Su; Ying Hong-Mei, Radiation Oncology (2011) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Value of renal resistive index in hepatitis C virus related liver cirrhosis and its response to midodrine
Negative / Null Result ReportAnesthetic Oxygen Use and Sex Are Critical Factors in the FLASH Sparing Effect
Negative / Null Result ReportClinical outcome and safety of selective renal artery embolization using permanent occlusive agents for acute renal bleeding
Negative / Null Result ReportIntra-fractional geometric and dose/volume metric variations of magnetic resonance imaging-guided stereotactic radiotherapy of prostate bed after radical prostatectomy
Negative / Null Result ReportComparison of the Main Staging Systems for Assessing the Severity of Lung Injury in Patients with COVID-19 and Evaluation of Their Predictive Value
Negative / Null Result ReportDosimetric Comparison and Plan Evaluation of Different Dose Computing Algorithms for Different Radiotherapy Techniques in Head and Neck Tumors
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.1186/1748-717x-6-4
