Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Philip J Batterham, Alison L Calear, Matthew Sunderland et al. · 2021 · Journal of Medical Internet Research
BackgroundPsychosocial, self-guided, internet-based programs are effective in treating depression and anxiety. However, the community uptake of these programs is poor. Recent approaches to increasing engagement (defined as both uptake and adherence) in internet-based programs include brief engagement facilitation interventions (EFIs). However, these programs require evaluation to assess their efficacy. ObjectiveThe aims of this hybrid implementation effectiveness trial are to examine the effects of a brief internet-based EFI presented before an internet-based cognitive behavioral therapy self-
View details →Negative / Null Result ReportOpen accessMedicine (General)
Angelo Mottaran, Amelio Ercolino, Lorenzo Bianchi et al. · 2023 · Medicina
Background and Objectives : The aim of this article is to present a single-surgeon, open retroperitoneal lymph node dissection (RPLND) series for testicular cancer in a high-volume center. Materials and Methods : We reviewed data from patients who underwent RPLND performed by an experienced surgeon at our institution between 2000 and 2019. We evaluated surgical and perioperative outcomes, complications, Recurrence-Free Survival (RFS), Overall Survival (OS), and Cancer-Specific Survival (CSS). Results : RPLND was performed in primary and secondary settings in 21 (32%) and 44 (68%) patients, res
View details →Negative / Null Result ReportOpen accessSports medicine
Genevieve Fraipont, Victor Hung, Michelle McGarry et al. · 2025 · Orthopaedic Journal of Sports Medicine
Objectives: The medial ulnar collateral ligament (UCL), the radiocapitellar joint, and the posteromedial olecranon are the constraints of the elbow that are often injured during the late cocking and early acceleration phases of throwing. Osteochondritis dissecans (OCD) of the capitellum usually occur in adolescents participating in baseball due to repetitive compression force and excessive valgus torque within the radiocapitellar joint. Currently, there is conflicting literature on how location and size of osteochondral defects effect elbow valgus angulation. The purpose of this study was to q
View details →Negative / Null Result ReportOpen accessPhysics
Bahadir Tamer · 2021 · EPJ Web of Conferences
The MIT BEAVRS benchmark problem, which was primarily setup for the verification and validation of high-fidelity tools that have coupled neutron transport, thermal-hydraulics, and fuel isotopic depletion models, has also found extensive usage in the reactor physics community for validating core analysis tools. The primary purpose of this paper is to provide an accurate, comprehensive evaluation of the BEAVRS benchmark with CASMO5 and SIMULATE5 codes. The CMS5 calculated results for low-power physics tests (hot zero power critical boron, control rod worth and isothermal temperature coefficients
View details →Negative / Null Result ReportOpen accessInternal medicine
Cansu Önlen Güneri, Hamza Malik Okuyan, Gülay Gülbol Duran et al. · 2022 · Ķazaķstannyṇ Klinikalyķ Medicinasy
Aim: Patients infected with the hepatitis B virus (HBV) are at a higher risk of cirrhosis and hepatocellular carcinoma. Despite the recent advancement of antiviral therapy, many patients still cannot respond to existing therapies. Hence, to detect the changes in liver function earlier, non-invasive methods are needed. Long non-coding RNAs (lncRNAs) play important roles in essential biological process as well as human cancer. LncRNAs may be used as biomarkers in human diseases. Thus, in this study, we purposed to analyze the expression levels of lncRNAs (HOX transcript antisense RNA (HOTAIR), m
View details →Negative / Null Result ReportOpen accessMedicine
Shiro Okumura, Hironori Koga, Kuniyo Inouye et al. · 2014 · Toxins
Parasporin-4 (PS4) is an aerolysin-type β-pore-forming toxin produced by Bacillus thuringiensis strain A1470. It exhibits specific cytotoxicity against human cancer cell lines; therefore, it is expected to be useful for the diagnosis and treatment of particular types of cancer cells. We examined the acute toxicity of PS4 on ICR mice. The LD50 value was 160 μg/kg by a subcutaneous route. Potassium, ammonium, magnesium ion, creatinine, and urea nitrogen decreased in urine by the injection of PS4. Simultaneously, creatinine and urea nitrogen in mice serum increased. These results imply that PS4 i
View details →Negative / Null Result ReportOpen accessMedicine
Yanwei Li, Dongchuan Yu · 2015 · PLoS ONE
Children's emotion word comprehension (EWC) has constantly received a great deal of attention in developmental science. However, since previous reports focused on only English emotion vocabulary, researchers thus far remained unclear as to the developmental trajectories of EWC (to Chinese emotion words) in Chinese children, let alone the cross-cultural difference of EWC in different languages (i.e., English V.S. Chinese). Furthermore, the influence of valence on EWC, as well as the interaction mechanism between EWC and empathy, has not been fully investigated. Finding answers to these research
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Yong Li, Yong Li, Junlan Wu et al. · 2022 · Frontiers in Oncology
ObjectiveBrain metastasis from colorectal cancer (CRC) is rare. Although stereotactic radiotherapy (SRT) and stereotactic radiosurgery (SRS) are effective treatments for brain metastasis, reports on brain metastasis of CRC are limited. This study compared the efficacy of SRT and SRS for the treatment of brain metastases from CRC and analysed the related factors to reveal the specificity CRC-derived brain metastasis.MethodsA retrospective analysis of 116 patients with brain metastases from colorectal cancer was performed and included 56 patients in the SRT group and 60 patients in the SRS group
View details →Negative / Null Result ReportOpen accessNuclear engineering. Atomic power
Jei Ha Lee, Cha Soon Kim, Soo Im Choi et al. · 2019 · Nuclear Engineering and Technology
Tritium is an important nuclide that must be monitored for radiation safety management. In this study, HTO was orally administered to rats at the level of 37 kBq (1 μCi) or 370 kBq (10 μCi) to examine tissue distribution and excretion levels. After sacrifice, wet and dry tissue samples were weighed and analyzed for tissue free-water tritium (TFWT) and organically bound tritium (OBT). The mean tissue concentrations of TFWT (OBT) were 30.9 (17.8) and 4.4 (8.1) Bq/g on days 7 and 13 at the 37 kBq level and 30.8 (64.6) Bq/g on day 17 at the 370 kBq level. To assess the cytogenetic damage due to tr
View details →Negative / Null Result ReportOpen accessDentistry
S.Shojaeddin Shayegh, Parviz Amini, Kaveh Yaghmai et al. · 2016 · Journal of Islamic Dental Association of Iran
Background and Aim: Several methods are available for intraoral repair of chipped porcelain restorations by composite resin. Also, there is still controversy regarding the best method of porcelain repair in terms of bond strength and cost effectiveness. This study aimed to compare three methods of porcelain surface treatment on shear bond strength (SBS) of composite to porcelain. Materials and Methods: This in vitro, experimental study was conducted on 30 porcelain blocks with a metal base in three groups. In group 1, porcelain surface was etched with hydrofluoric (HF) acid and silanized. Afte
View details →Negative / Null Result ReportOpen accessSurgery
Zhen Yu, Wenxing Xun, Pan Ren et al. · 2025 · World Journal of Surgical Oncology
Abstract Objective The purpose of our study was to evaluate the clinical effect of a facelift combined with a modified overlapping superficial musculoaponeurotic system (SMAS) flap for repairing facial depression caused by the resection of benign parotid lesions. Methods This retrospective, non-randomized observational study included 87 patients diagnosed with benign parotid tumors who underwent surgical treatment between June 2014 and September 2023. All patients were treated in our department or by the same surgical team after institutional transfer. All patients received surgery via a stand
View details →Negative / Null Result ReportOpen accessMedicine (General)
M.C. Azevedo, E.D.R.P. Velloso, V. Buccheri et al. · 2014 · Brazilian Journal of Medical and Biological Research
In adults with non-promyelocytic acute myeloid leukemia (AML), high-dose cytarabine consolidation therapy has been shown to influence survival in selected patients, although the appropriate doses and schemes have not been defined. We evaluated survival after calculating the actual dose of cytarabine that patients received for consolidation therapy and divided them into 3 groups according to dose. We conducted a single-center, retrospective study involving 311 non-promyelocytic AML patients with a median age of 36 years (16-79 years) who received curative treatment between 1978 and 2007. The 13
View details →Negative / Null Result ReportOpen accessMedicine
Yan Michael Li, Richard Francis Frisch, Zheng Huang et al. · 2021 · Asian Spine Journal
Study Design Retrospective chart review. Purpose This study compared the clinical and radiographic outcomes of patients treated with expandable and static interbody spacers following minimally invasive lateral lumbar interbody fusion (MIS-LLIF) with 12-month follow-up. Overview of Literature A common surgical option for the treatment of degenerative disk disease (DDD) is MIS-LLIF using static or expandable spacers to restore disk height (DH), neuroforaminal height (NH), and segmental lordosis. Static spacers may require excessive trialing and aggressive impaction, potentially leading to endpla
View details →Negative / Null Result ReportOpen accessAgriculture (General)
WANG Xiaofan, WU Yong, ZHANG ZHONG Lili et al. · 2021 · Guan'gai paishui xuebao
【Background and Objective】 Magnetizing the water prior to irrigation is a new technology developed over the past decades in China. The objective of this paper is to investigate how different irrigation water sources alter the effects of the magnetization on photosynthesis, physiological and biochemical characteristics, as well as the yield of lettuce. 【Method】 The experiment was conducted in a solar greenhouse with the Italian lettuce taken as the model plant. It consisted of non-magnetization (M0) and magnetization (M1); added to these are three irrigation water sources: fresh water (T1), rec
View details →Negative / Null Result ReportOpen accessDentistry
Elanur Yıldızoğlu, Melih Manir, Muhammet Karadas · 2026 · BMC Oral Health
Abstract Background This in-vitro study aimed to assess the effects of whitening toothpastes on color and translucency changes and surface roughness of resin composites. Methods Disk-shaped resin composite samples from each composite (Clearfil Majesty Esthetic, Palfique Estelite Paste, and Charisma Smart) were made and randomly allocated into five groups (n = 10): Crest Pro Health Whitening, Advance White Pro, Sensodyne Extra Whitening, a control group (distilled water), and a positive control group (exposed to only stain). The samples were exposed to a tea solution and brushed for 30 days. Su
View details →Negative / Null Result ReportOpen accessMedicine
Shermineh Heydari, Ladan Kashani, Mehrdad Noruzinia · 2021 · Iranian Journal of Allergy, Asthma and Immunology
Endometriosis is a common, chronic, inflammatory disorder in women, characterized by the presence of endometrial tissue outside the uterus cavity. The disease affects ~10% of women during their reproductive age. There is some debates on the pathogenesis of endometriosis and its mechanism among the scientists; therefore, different hypotheses have been suggested. According to Sampson theory, a possible mechanism for seeding ectopic endometriotic lesions is a dysregulation of endometrial mesenchymal stem cells (eMSCs). In the present study, we evaluated the expression of candidate genes in eMSCs
View details →Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Akash Bihari Pati, Pritinanada Mishra, Santosh K Mahalik et al. · 2023 · Indian Journal of Urology
Introduction: Proximal hypospadias repair has many postoperative complications such as urethrocutaneous fistulae, wound dehiscence, and urethral stricture. The beneficial effect of estrogen to promote wound healing has been known. We designed a study to determine whether preoperative stimulation of tissue with estrogen can reduce the postoperative complications associated with wound healing in patients undergoing hypospadias repair. Methods: Patients with proximal hypospadias requiring two-stage repairs (chordee correction followed by urethral tubularization) were randomized to estrogen and co
View details →Negative / Null Result ReportOpen accessAnimal culture
Heng Wang, Lin Liu, Xi He et al. · 2025 · The Journal of Poultry Science
Betaine has been proposed as a low-cost source of methyl groups in poultry feed, replacing methionine and choline. The present study aimed to investigate the effect of betaine on growth performance, methionine metabolism, and methyl transfer in broilers aged 1 to 21 days fed a low-methionine diet. A total of 960 one-day-old male broilers were randomly divided into four groups: positive control (0.62% methionine in the diet), negative control (0.37% methionine in the diet), and two treatment groups (0.37% methionine in the diet plus either 1500 or 3000 mg betaine/kg diet). Chicks fed the 1500 m
View details →Negative / Null Result ReportOpen accessAgriculture (General)
Patrícia Maria Ribeiro Campos Pereira, Marcos Franke Pinto, Urbano Gomes Pinto de Abreu et al. · 2009 · Pesquisa Agropecuária Brasileira
O objetivo deste trabalho foi avaliar parâmetros de carcaça, características físico-químicas e de qualidade de carne de novilhos machos superprecoces. Foram avaliados três grupos raciais com 8 animais Nelore (N), 18 ¼ Abeerden Angus ½ Nelore (AN) e 18 ½ Limousin ¼ Abeerden Angus ¼ Nelore (LAN), com idade entre 7,5 e 11,5 meses no início do experimento, abatidos após 143 dias de confinamento. Os animais AN apresentaram maior peso ao abate, ganho médio diário de peso, peso de carcaça e comprimento de carcaça; os animais LAN apresentaram maior rendimento de carcaça e área de olho de lombo. Os ani
View details →Negative / Null Result ReportOpen accessBiotechnology
Enkelejda Velo, Fabrizio Balestrino, Fabrizio Balestrino et al. · 2022 · Frontiers in Bioengineering and Biotechnology
The pathogen transmitting Aedes albopictus mosquito is spreading rapidly in Europe, putting millions of humans and animals at risk. This species is well-established in Albania since its first detection in 1979. The sterile insect technique (SIT) is increasingly gaining momentum worldwide as a component of area-wide-integrated pest management. However, estimating how the sterile males will perform in the field and the size of target populations is crucial for better decision-making, designing and elaborating appropriate SIT pilot trials, and subsequent large-scale release strategies. A mark-rel
View details →Negative / Null Result ReportOpen accessMedicine
Koji Komatsu, Yoichiro Masuda, Hoshiho Kubota et al. · 2025 · Scientific Reports
Abstract The study aimed to investigate whether eosinophil major basic protein (MBP), which is linked to cataract formation due to lens epithelial cell (LEC) damage in atopic dermatitis (AD), is associated with intraocular lens (IOL) dislocation. This retrospective observational study was conducted at a Medical University Hospital and included 22 eyes (10 AD, 12 non-AD [NAD]) that underwent IOL explantation and fixation. Surgeries were conducted to extract the intraocular lens capsule for morphological evaluations. Quantitative analysis of the MBP staining was conducted using the staining area
View details →Negative / Null Result ReportOpen accessZoology
Vida Hojati, Reza Babaei Savasari · 2014 · International Journal of Zoology
The Caspian bent-toed gecko, Tenuidactylus caspius, is one of the most common nocturnal lizards of Iran with widespread distribution especially in the northern provinces. This research was done in order to study the diet and sexual dimorphism of this species in Sari County from 5 May to 20 October. During this research, 40 specimens of them including 20 males and 20 females were studied for diet and 140 specimens including 70 adult males and 70 adult females were studied for sexual dimorphism. Prey items identified were insects that belong to 15 species of 8 families and 6 orders. The most com
View details →Negative / Null Result ReportOpen accessAgriculture
K. Javidrahmdel; H. Allaf noveirian; B. Falahatkar; A. Babakhani lashkan · 2017 · Majallah-i ̒Ilmī-i Shīlāt-i Īrān
The present study was conducted to determine the effect of fish meal replacement with sunflower meal on growth performance, feed efficiency and body proximate composition of common carp fingerlings. Five experimental diets with replacement levels of 0, 25, 50, 75 and 100% of fish meal with sunflower meal were formulated with equal protein, fat and energy contents. Fish meal proportion of control diet was 28%. Fish with average weight of 3.03 ± 0.36 g were distributed in 15 fiberglass tanks. After 10 weeks of feeding by experimental diets, growth performance and feed efficiency were evaluated a
View details →Negative / Null Result ReportOpen accessMedicine (General)
Jo Howard, Sophie A. Lee, Baba Inusa et al. · 2019 · Trials
Abstract Design This randomised crossover trial compared nocturnal auto-adjusting continuous positive airway pressure (APAP) and nocturnal oxygen therapy (NOT) in adults and children with sickle cell anaemia, with patient acceptability as the primary outcome. Secondary outcomes included pulmonary physiology (adults), safety, and daily pain during interventions and washout documented using tablet technology. Methods Inclusion criteria were age > 8 years and the ability to use an iPad to collect daily pain data. Trial participation was 4 weeks; week 1 involved baseline data collection and week 3
View details →Negative / Null Result ReportOpen accessMedicine
Lin C, Mei YM, Yan Y et al. · 2026 · Head & face medicine
AIM: To evaluate the adjunctive clinical efficacy of manual root planing following ultrasonic subgingival debridement (SD) in the treatment of generalized severe periodontitis. MATERIAL AND METHODS: Twenty-nine patients diagnosed with…
View details →Negative / Null Result ReportOpen accessMedicine
Bilinç Doğruöz Karatekin, Şeyhmus Yasin, Yasemin Yumuşakhuylu et al. · 2021 · Bagcilar Medical Bulletin
Objective:Sarcopenia and osteoporosis share common risk factors and biological pathways. In the present study, patients with postmenopausal osteoporosis were screened for sarcopenia using the algorithm proposed by the European Working Group on Sarcopenia in Older People (EWGSOP) and balance impairment was investigated in sarcopenic patients.Method:Fifty three postmenopausal osteoporotic patients were evaluated for sarcopenia as per the algorithm proposed by the EWGSOP. Among the parameters included in the algorithm, gait speed was assessed using the timed up&go test (TUG), Jamar hand dynamomet
View details →Negative / Null Result ReportOpen accessEducation (General)
Nur Maziyah Ulya · 2016 · Nadwa
This study aims to analyze: (1) The difference of students‟ achievement between students studying at cooperative learning class and those studying at conventional learning class; (2) The difference of students‟ achievement between the introvers and the extroverts; (3) The interactive influence between learning method and students‟ personality type toward students‟ achievement in Arabic language. This research used experimental design conducted at MAN 1 Semarang.. The result of this research shows that: (1) There is significant difference in students‟ achievement between students studying at th
View details →Negative / Null Result ReportOpen accessPharmacy and materia medica
Comfort Nanbam Sariem, Maxwell Patrick Dapar, Nenman Musa Lenka et al. · 2022 · INNOVATIONS in Pharmacy
Background: The prolonged multi-drug treatment regimen for tuberculosis (TB) can lead to non-adherence and unsuccessful treatment outcomes. Educational and psychological health models can be used to design cognitive and behavioral interventions to improve adherence and treatment outcomes. Objective: To determine the effect of cognitive and behavioral interventions on TB treatment outcomes. Methods: The quasi-experimental study conducted in six TB treatment centers involved reinforced medication education and adherence counseling (MEAC), designed from a structured validated psychometric scale.
View details →Negative / Null Result ReportOpen accessAgriculture (General)
LI Yexin, LYU Gang, WANG Daohan et al. · 2023 · Guan'gai paishui xuebao
【Objective】 Restoring coal mining waste dumps is a way to alleviate their detrimental impact on environment. In this paper, we present the results of an experimental study on distribution and stability of soil aggregates in a reclaimed coal mining overburden dump. 【Method】 The experiment was carried out at a reclaimed coal mine dump site in a grassland region in northern China. We measured the development of fissures from Zone I (GF) to Zone three (GFIII) in the fissure zone. The composition and distribution soil aggregates in these zones were determined using dry-wet sieve method. Aggregate s
View details →Negative / Null Result ReportOpen accessVocational rehabilitation. Employment of people with disabilities
Zahid Mehmood, Zubair Ahmad, Asad Ullah et al. · 2023 · The Rehabilitation Journal
Background: Understanding students' perception of the educational environment and their cognitive load in this context is crucial for optimizing the effectiveness of e-learning platforms. Objective: To compare educational environment perception and cognitive load in under-graduates Doctor of Physical Therapy (DPT) and post-graduate Master in Science of Physical Therapy (MSPT) students having online learning experiences. Methodology: In this comparative cross-sectional study, data was collected through non-probability convenient sampling from n=274 under-graduates DPT (n=225) and post-graduates
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