Negative / Null Result ReportMedicine
Mildner FO, Sykora MM, Hackl H et al. · 2024 · Lung cancer (Amsterdam, Netherlands)
Background Cancer immune evasion is critical in non-small cell lung cancer (NSCLC) and has been targeted by immunotherapy. High soluble (s)PD-L1 is associated with reduced survival and treatment failure in advanced stages. Here we…
View details →DOI: 10.1016/j.lungcan.2024.107955 Negative / Null Result Report
Johnson MS, Adams VM, Byrne J · 2024 · Preprint
Abstract Effective adaptation to climate risks requires identifying and realizing community beliefs about which locations require management attention. Environmental planners and asset managers, especially those in rural and regional…
View details →DOI: 10.21203/rs.3.rs-3412143/v1 Negative / Null Result ReportOpen accessMedicine
Le NT, Nguyen TG, Huynh NYN et al. · 2025 · Scientific reports
Dietary calcium's role in human health and disease prevention is inconclusive. We examined the associations between dietary calcium intake and the risk of overall and specific causes of mortality. A prospective cohort study was performed…
View details →DOI: 10.1038/s41598-025-10484-2 Negative / Null Result ReportOpen accessMedicine
Manni G, Pambianco M, Sicuro C et al. · 2025 · International journal of molecular sciences
Hepatic actinomycosis (HA) and IgG4-related inflammatory pseudotumors are rare and often overlooked causes of liver mass, which can easily be misdiagnosed as primary liver cancer or metastasis. Diagnosis is arduous due to unspecified…
View details →DOI: 10.3390/ijms26199420 Negative / Null Result ReportOpen accessMedicine
Borz-Baba L, Aydin A, Parvin R · 2026 · Cureus
Metabolic-associated steatotic liver disease (MASLD) is a common medical condition that can progress to metabolic-associated steatohepatitis (MASH) and advanced fibrosis, leading to severe outcomes. Liver biopsy continues to be the…
View details →DOI: 10.7759/cureus.103284 Negative / Null Result ReportMedicine
Sakuma K, Yoshimura K · 2026 · Journal of environmental radioactivity
Tritium ( 3 H) is the principal radionuclide remaining in ALPS-treated water discharged from the Fukushima Dai-ichi Nuclear Power Plant (FDNPP), and its potential environmental impact has drawn considerable attention. To evaluate possible…
View details →DOI: 10.1016/j.jenvrad.2026.108055 Negative / Null Result Report
Jhaveri k, Mai N, Anjos CHd et al. · 2024 · Preprint
Abstract After disease progression on endocrine therapy (ET) plus a CDK4/6 inhibitor, there is no standardized sequence for subsequent treatment lines for estrogen receptor positive (ER+) metastatic breast cancer (MBC). CDK4/6i retrial as…
View details →DOI: 10.21203/rs.3.rs-4237867/v1 Negative / Null Result ReportOpen accessMedicine
Needle R, Yu Y, Soualhine H et al. · 2025 · Biomedicines
Background/Objectives : The diagnosis of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacterial (NTM) infections is accomplished by three main diagnostics methods: smear microscopy, culture, and molecular testing.…
View details →DOI: 10.3390/biomedicines13102416 Negative / Null Result ReportOpen accessMedicine
Kirby C, Baldwin JA, Elwell K et al. · 2026 · Healthcare (Basel, Switzerland)
Background The literature shows inconclusive results from utilizing motivational interviewing (MI) in indigenous populations to address early childhood caries (ECC). Great Beginnings for Healthy Native Smiles (GBHNS) (NIDCR U01DE028508), a…
View details →DOI: 10.3390/healthcare14081059 Negative / Null Result Report
Fan J, Zeng F, Zhong H et al. · 2024 · Preprint
Abstract Cigarette smoking is posited as a potential factor in disrupting the balance of the human gut microbiota. However, existing studies with limited sample size have yielded inconclusive results. Here, we assessed the association…
View details →DOI: 10.21203/rs.3.rs-4274545/v1 Methods Dead-EndMedicine
Reis da Silva T · 2024 · British journal of community nursing
Aim This study reviews research into the effects of the supplementation of B12 in the prevention and recovery of mental illness, and the potentiation of psychotropic medication. Methodology This literature review follows a systematic…
View details →DOI: 10.12968/bjcn.2024.29.3.137 Negative / Null Result ReportOpen accessMedicine
Zhang Y, Baharani J, Ajayi B et al. · 2025 · BMC nephrology
Background Fibrillary glomerulonephritis (FGN) is a rare immune complex-mediated glomerulonephritis characterised by the deposition of anomalous fibrillary structures within the glomeruli. The prognosis for patients with FGN is usually…
View details →DOI: 10.1186/s12882-025-04187-z Negative / Null Result ReportOpen accessMedicine
Gobishangar S, Abiharan P, Jenil A et al. · 2026 · Cureus
Background The appendix is a vermiform structure with a variable position, length, and thickness. Imaging plays a critical role in diagnosing an inflamed appendix, with non-contrast computed tomography (NCCT) being an effective modality…
View details →DOI: 10.7759/cureus.102357 Negative / Null Result ReportMedicine
Bronkhorst H, Kalaykova S, Huysmans MC et al. · 2024 · Journal of dentistry
Objective This study presents a scoping review to determine the association between tooth wear and bruxism. Data A protocol was developed a priori (Open Science Framework (DOI 10.17605/OSF.IO/CS7JX)). Established scoping review methods…
View details →DOI: 10.1016/j.jdent.2024.104983 Negative / Null Result ReportMedicine
Nieminen V, Martikainen MV, Kalliomäki S et al. · 2024 · International journal of radiation biology
Purpose Earlier evidence suggests that extremely low frequency magnetic fields (ELF MFs) can modify the effects of carcinogenic agents. However, the studies conducted so far with ionizing radiation as the co-exposure agent are sparse and…
View details →DOI: 10.1080/09553002.2024.2369105 Negative / Null Result ReportMedicine
Gaviria M, Arave M, Phan N et al. · 2026 · Military medicine
Introduction Peripheral nerve injuries (PNIs) are associated with significant morbidity, and traditional repair techniques often result in incomplete functional recovery. Polyethylene glycol (PEG) fusion has been proposed as a technique to…
View details →DOI: 10.1093/milmed/usag235 Negative / Null Result ReportOpen accessMedicine
Larson ME, Pan Y, Reidy L et al. · 2026 · PloS one
People with HIV (PWH) experience elevated cardiovascular disease risk compared to people without HIV. Stimulant use may further increase subclinical myocardial injury among PWH, but data on cardiovascular biomarkers, including serum…
View details →DOI: 10.1371/journal.pone.0350086 Negative / Null Result ReportMedicine
Geamănu A, Pîrvulescu RA, Tricorache D et al. · 2026 · Diagnostics (Basel, Switzerland)
Background: Hydroxychloroquine (HCQ) is widely used in systemic lupus erythematosus (SLE), yet cumulative exposure may result in progressive retinal toxicity. Structural biomarkers capable of identifying subclinical damage remain…
View details →DOI: 10.3390/diagnostics16121867 Negative / Null Result ReportMedicine
Sung K · 2026 · Environmental management
Trail penetration within strictly designated protected areas is often treated as a conservation concern, yet its consequences for vegetation trends at national scales remain empirically unresolved. This study evaluated whether trail…
View details →DOI: 10.1007/s00267-026-02544-8 Negative / Null Result ReportMedicine
Simonis L, Marcour Y, Embacher J et al. · 2026 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Assessment of hepatic steatosis is key for diagnosis and monitoring of steatotic liver disease. Controlled attenuation parameter is widely used, but concerns regarding its measurement variability exist. We evaluated the…
View details →DOI: 10.1016/j.cgh.2026.05.006 Negative / Null Result ReportMedicine
Ünlü C, Aksoy H · 2026 · BMC pregnancy and childbirth
Background Anti-D immunoglobulin administered in the early third trimester to Rhesus D negative women with Rhesus D incompatibility is widely assumed to provide protection against silent fetomaternal haemorrhage until delivery. However,…
View details →DOI: 10.1186/s12884-026-09530-2 Negative / Null Result ReportOpen accessMedicine
Corn E, Becht K, Adefres B et al. · 2026 · Gynecologic oncology reports
Purpose Cervical cancer is the number one cause of cancer-related mortality for women in Botswana, where care is complicated by the country's severe shortage of gynecologic oncologists. Recent data suggests that "low-risk" stage I cervical…
View details →DOI: 10.1016/j.gore.2026.102089 Negative / Null Result ReportOpen accessMedicine
Martinos N, Kroupis C, Gypari M et al. · 2026 · Current issues in molecular biology
Background/objectives Histologic mucosal healing is an increasingly recognized therapeutic target in inflammatory bowel disease (IBD), yet reliable non-invasive correlates remain limited. This study aimed to evaluate circulating cytokine…
View details →DOI: 10.3390/cimb48050516 Methods Dead-End
Kim EJ, Kim SY, Kee YK et al. · 2026 · Preprint
Abstract Far-infrared (FIR) therapy has been proposed to improve vascular access flow (Qa) in patients receiving maintenance hemodialysis through an arteriovenous fistula (AVF) or arteriovenous graft (AVG). However, vascular access blood…
View details →DOI: 10.21203/rs.3.rs-9732400/v1 Methods Dead-End
Han P, Chen P, Zhang L et al. · 2026 · Preprint
Abstract Background Small-incision lenticule extraction (SMILE) removes an intrastromal lenticule whose stiffness differs between corneal meridians, producing measurable stromal mechanical anisotropy. Whether this meridional anisotropy…
View details →DOI: 10.21203/rs.3.rs-9942382/v1 Negative / Null Result ReportOpen accessMedicine
Walmsley SL, Nabipoor M, Qi F et al. · 2026 · Clinical & translational immunology
Objectives To assess neutralizing antibody responses to emerging SARS-CoV-2 variants. Methods We explored SARS-CoV-2 neutralizing antibodies in140 adults participating in a longitudinal study of antibody responses to COVID vaccines.…
View details →DOI: 10.1002/cti2.70095 Negative / Null Result ReportOpen accessMedicine
Bermingham MD, Meredith RT, Mills H et al. · 2026 · Frontiers in allergy
Quantifying food allergens in complex matrices is hindered by thermal processing, particularly in baked products used for oral food challenges (OFCs), where limited data exists on effects on clinically relevant allergens. To address this,…
View details →DOI: 10.3389/falgy.2026.1796342 Negative / Null Result ReportOpen accessMedicine
Kennedy J, Cooley SA, Roman Fox J et al. · 2026 · The Journal of infectious diseases
Background As persons with human immunodeficiency virus (PWH) live longer, interactions between human immunodeficiency virus (HIV), aging, and structural brain integrity become increasingly vital for understanding cognitive disorders. This…
View details →DOI: 10.1093/infdis/jiag029 Failed Experiment ReportMedicine
Watrobska CM, Codd J, Portugal SJ et al. · 2026 · The Journal of experimental biology
The brain is energetically expensive. Therefore, energy availability may determine whether costly cognitive processes such as long-term memory can be expressed. However, there is a limited understanding of the metabolic costs associated…
View details →DOI: 10.1242/jeb.250403 Negative / Null Result ReportMedicine
Kuo MC, Younan SA, Williams PJ et al. · 2026 · Techniques in coloproctology
Background Robotic approach is increasingly being used for surgery in Crohn's disease. Robotic ileocolic resection (ICR) for Crohn's disease (CD) is comparable to laparoscopic ICR for short term outcomes; however, no studies have compared…
View details →DOI: 10.1007/s10151-026-03367-9 