A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21385 results · page 696 of 713
Ade Harwoko, Lestari Kurniawati · 2022 · Jurnal Akademi Akuntansi
This study aims to determine changes in corporate tax aggressiveness after the application of Statement of Financial Accounting Standards (PSAK) 73. The sample of this research is the financial statements of pharmaceutical industry…
Tóth Štefan, Olexa Peter, Hertelyová Zdenka et al. · 2020 · Open Chemistry
The aim of this study was to detect the concentrations of PCSK9 in various subclinical stages of atherosclerosis and to highlight its relationship with inflammation. One hundred and fifty-nine healthy patients were divided into three groups, based on the extent of atherosclerotic changes in the carotid artery: a group without identifiable atherosclerosis, cIMT>75‰ and an asymptomatic plaque group. The PCSK9 was measured by ELISA and hsCRP by the immunoturbidimetric method. Vascular changes were identified by a carotid ultrasound. PCSK9 was elevated, when comparing the healthy group with the cI
Indra Hidayat, Erna Setiawati, Tanti Ajoe Kesoema et al. · 2023 · Jurnal Kedokteran Diponegoro
Background: Smartphone with all of its benefits make the majority of its users become too attached with the device that can fulfil their various needs. Due to its accessibility, an increase of daily screen time has also been observed which may have negative impacts on health, one of them being De Quervain’s Syndrome. De Quervain’s Syndrome is a type of Repetitive Strain Injury, affecting the thumb and wrist caused by a repetitious activity that puts burden or trauma to the aforementioned body parts. Objective: To assess the correlation between duration of screen time and method of handling sma
Salih Gülen, İsmail Dönmez, Fatma Betül Şengönül et al. · 2025 · SAGE Open
STEM education aims to develop 21st-century skills, support economic growth and promote gender equality in STEM fields. It is known that gender stereotypes play a significant role in the formation of STEM identity. The most important factor preventing some high school-level female students from pursuing STEM careers is their lack of participation in STEM activities. Female students in high schools have limited opportunities to explore or learn about STEM careers due to the emphasis on verbal and religious courses in their curriculum. However, it is known that women can work more autonomously i
Memota Laishram, Krishnagopal Srikanth, AR Rajalakshmi et al. · 2017 · Journal of Clinical and Diagnostic Research
Introduction: Macular disease is the leading cause of low vision in the Western world. Drusen and pigmentary irregularities are common among the rural Northern Indian population. The disease process leads to loss of central vision, metamorphopsia, macropsia or micropsia and colour vision defect. Aim: To study the retinal sensitivity changes in macular diseases using microperimetry. Materials and Methods: It was an observational study, conducted in the Department of Ophthalmology at a rural tertiary care hospital. This study was started from December 2014 until June 2016, in all patients with m
Amika K. Sood, Allison J. Burbank, Michael Lawson et al. · 2019 · Respiratory Research
Abstract Background Endotoxin is a component of particulate matter linked to respiratory disease. Our group has shown that experimental endotoxin inhalation challenge reproducibly triggers neutrophilic inflammation in the airways and in peripheral blood. Sputum induction is currently the only available method for assessing airway neutrophilia but is laborious and time-consuming. This analysis examined the correlation between systemic and airway inflammatory responses to endotoxin to determine if peripheral blood could serve as a surrogate marker for neutrophilic airway inflammation. Methods We
Jun Yeong Jo, Chi Bum Bahn, Hwasung Yeom · 2024 · Nuclear Engineering and Technology
The dissolved oxygen in a coolant can affect the oxidation properties of structural materials. A desirable oxide phase formation is achieved by manipulating the oxygen level in the coolant, which can mitigate structural material degradation in nuclear power plants. Therefore, the role of dissolved oxygen in the corrosion of structural materials in aqueous environments needs to be understood. In this study, a short-term corrosion test (up to 300 h) of Ferritic/Martensitic steels (F/M steels; FeCrW model alloys), namely, Fe12Cr1W, Fe9Cr1W, and Fe9Cr, in stagnant water at 360 °C was performed in
Rostami Shilan, Fathollahpour Asadollah, Abdi Mohammad et al. · 2018 · Journal of Medical Biochemistry
Background: There is a paucity of studies regarding oxidative balance and selenium (Se) status in congenital hypothyroidism. Recently, more attention has been given to the use of Se supplementation as a new treatment for thyroid disorders. Oxidative stress increases in different thyroid disorders and causes many pathological outcomes. The present study aimed to determine the serum prooxidant-antioxidant balance (PAB), Se, thyroid stimulating hormone (TSH) and free thyroxine (FT4) concentration in congenital hypothyroidism (CH) patients and the association of their probable change with hematolo
Fatma Sargin, Mehmet Alçı, Büşra Kaygusuz Aydemir et al. · 2026 · BMC Pediatrics
Abstract Background Childhood epilepsy is one of the most common neurological disorders worldwide, significantly affecting cognitive, emotional, and social development. As caregivers often seek medical guidance online, the readability, understandability, and quality of internet-based patient education materials (IPEMs) are crucial for health literacy and decision-making. This study evaluates the readability, understandability, quality, and popularity of online pediatric epilepsy materials in relation to established health communication standards. Methods A Google search using the term ‘epileps
Huanhuan Zuo, Xiaochen Xie, Jiahuan Peng et al. · 2019 · Analytical Cellular Pathology
Recently, there has been an increasing interest in the potential clinical use of several inflammatory indexes, namely, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic-immune-inflammation index (SII). This study aimed at assessing whether these markers could be early indicators of pulmonary hypertension (PH) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). A total of 185 patients were enrolled in our retrospective study from January 2017 to January 2019. Receiver operating characteristic curve (ROC) and area under the
Simone Maria Muniz da Silva Bezerra, Eduardo Tavares Gomes, Paulo César da Costa Galvão et al. · Revista Brasileira de Enfermagem
ABSTRACT Objective: To characterize relations between spiritual well-being and hope of patients in the preoperative period of cardiac surgery. Method: Exploratory cross-sectional study with quantitative approach, performed in the infirmaries of a reference hospital in cardiology. We evaluated 69 patients hospitalized in preoperative period of myocardial revascularization, valve repair or replacement. Results: We verified that patients hold relevant scores of hope and welfare in all areas, being the existential well-being significantly lower than the religious one. The average of the spiritual
Ovi Sofia, Muna Amalia, Herryanto Thomassawa et al. · 2024 · Interdisciplinary Perspectives on Infectious Diseases
Introduction. The imbalance of the immune response is an important factor contributing to the incidence of ocular toxoplasmosis (OT). Regulatory T cells (Treg) play a key role in maintaining the balance between Th1 and Th17 immune responses, while interleukin-27 (IL-27) levels are related to the differentiation of Th17 cells. This study analyzes the differences in the number of Treg cells and the level of IL-27 between OT patients and seropositive individuals without ocular lesions and its correlation with retinal lesion size. Methods. This analytic observational study, conducted for 8 months,
Neal Singleton, Vaughan Poutawera · 2017 · Journal of Orthopaedic Surgery
Aim: It has been reported in the literature that patients with poor preoperative mental health are more likely to have worse functional outcomes following primary total hip and knee arthroplasty. We could find no studies investigating whether preoperative mental health also affects length of hospital stay following surgery. The aim of this study was to determine whether preoperative mental health affects length of hospital stay and long-term functional outcomes following primary total hip and knee arthroplasty. We also aimed to determine whether mental health scores improve after arthroplasty
Divya Anantharaman, Aiswaryah Radhakrishnan, Vidhyalakshmi Anantharaman · 2023 · Journal of Pregnancy
Aim. Multisystemic physiological changes in pregnancy can result in tear film and refractive changes in the eye. We report dry eye prevalence in pregnant women using Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire. Methods. The SPEED questionnaire was self-administered cross-sectionally to 428 pregnant women (mean age: 26.8±4.4 years) with clinically confirmed pregnancy from two obstetric clinics in Chennai, India. Subjects with predisposing risk factors for dry eye were excluded from the study. Subjects were categorized as normal, moderate, and severe dry eye based on the SPE
C.D. Araújo, G.S. Sanches, F. Borek et al. · 2023 · Arquivo Brasileiro de Medicina Veterinária e Zootecnia
ABSTRACT KIT protein is associated with the etiology of canine mast cell tumors (MCT); however, the expression patterns of KIT are highly variable. The aim of this study was to determine if KIT patterns are related with eosinophil count in MCT. Hematoxylin eosin and May Grünwald-Giemsa stain techniques were applied, histological grading and eosinophil counting were performed in 48 MCT samples. Immunohistochemical evaluation was performed with IL-5, VEGFr, and c-KIT antibodies. The percentage of immunolabeling with IL-5 and VEGFr was determined, and the samples incubated with c-KIT were graded
Manoochehr Nakhjavani, Firouzeh Asgarani, Fatemeh Esfahanian et al. · 2009 · Acta Medica Iranica
Accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. To evaluate the association of oxidized low- density lipoprotein (ox-LDL) with the development of diabetic nephropathy, plasma level of ox-LDL were measured in 70 diabetic patients with macro and 63 patients with normoalbuminuria. The plasma oxidized- LDL level in patients with macroalbuminuria was higher than those in normoalbuminuric group, (85.72 ± 32.92 mu/L versus 75.07 ± 26.46 u/L, P= 0.041).
Dewi Kania Intan Permatasari, Tenny Setiani Dewi, Dewi Marhaeni Diah Herawati · 2021 · Dental Journal
Background: Taste disorders often occur in the elderly, which can have serious consequences on their health status. Zinc and saliva volume have a role in maintaining taste acuity, especially in the elderly. Purpose: This study was to determine the correlation between salivary zinc levels, salivary volume, and taste disorders in elderly patients. Methods: This was a cross-sectional research. Elderly patients with and without taste disorders were included in this study. Salivary zinc levels were measured using the Atomic Absorption Spectrometry (AAS) method. Salivary volume was measured using th
Dou Qu, Xiaoni Zhong, Guiyuan Xiao et al. · 2018 · International Journal of Infectious Diseases
Objective: To evaluate adherence to pre-exposure prophylaxis (PrEP) in a clinical trial of a population of men who have sex with men (MSM), to explore the influence of social psychology and objective factors (e.g., forgetting, too busy) on adherence, and to provide evidence for subsequent PrEP research. Methods: This study analyzed the data from the daily medication group within a PrEP study (a randomized placebo-controlled trial of oral tenofovir among MSM in Western China from April 2013 to March 2015). A total of 331 participants were analyzed. PrEP adherence was self-reported by the subjec
Fatemeh Moghadasi-Boroujeni, Mansoureh Adel Ghahraman · 2020 · مجله پژوهش در علوم توانبخشی
Introduction: Romberg test is one of the balance screening tests. Since this test does not require special equipment, it is widely used in the evaluation of people suffering from balance disorders. This study aimed to determine the sensitivity of the Romberg test for the diagnosis of peripheral vestibular dysfunction compared with the caloric test that is the gold standard for the diagnosis of horizontal semicircular canal/superior vestibular nerve disorders.Materials and Methods: This study was a cross-sectional-comparative study and the sample was selected from those who referred to the audi
Joel Del Bel Pádua, Carolline Fontes Alves Mariano, Alexandre Todorovic Fabro et al. · 2024 · Biomarker Insights
Background: Immunohistochemical prognostic significance of the homologous recombination-related proteins RAD51, ATM, BRCA1, and BRCA2 is known in gastric adenocarcinoma, one of the deadliest cancers. Objective and design: This retrospective cohort study aimed to evaluate mRNA expression and promoter methylation of some homologous recombination-related genes in this neoplasm. Methods: We evaluated mRNA expression and methylation of RAD51 , ATM , ATR , BRCA1 , and BRCA2 in tumor and non-tumor frozen samples from gastrectomy specimens by RT-qPCR and MS-HRM, correlating our results with previous i
Aves Editorial Aves Editorial · 2019 · Urology Research and Practice
Abstract Introduction: Lower urinary tract symptoms (LUTS) associated with BPH and erectile dysfunction (ED) are common problems in aging male. In this study, we aimed to determine the causes of the relationship between LUTS and ED, and the possible effects of body mass index (BMI), serum leptin, free testosterone (fT) and lipid levels on LUTS and ED etiology. Materials and Methods: Between June 2003 and February 2004, 46 patients were recruited in this study. All patients underwent physical examination including digital rectal examination, urine analysis, uroflowmetry and residual urine volum
Baumann Gert, Gericke Christine, Mueller Simone et al. · 2010 · BMC Women's Health
Abstract Background Decreased levels of circulating bone marrow-derived progenitor cells have been associated with risk factors and cardiovascular diseases. Smoking is the most important modifiable risk factor for atherosclerosis in young women. The aim of this pilot study was to assess in healthy premenopausal women without other risk factors for cardiovascular disease the influence of nicotine abuse on the number of circulating progenitor cells in relation to endothelial function. Methods The number of endothelial progenitor cells, measured as colony-forming units in a cell-culture assay (EP
Manik Changoji Bhise, Arun Vishwambhar Marwale, Ashish Chandrakantrao Mohide et al. · 2019 · Annals of Indian Psychiatry
Background: Survivors of suicide experience psychological distress for years after suicide. In India, farmers' suicide survivors are special group, with unique set of stressors. There are very few studies examining this group in India. The objective was to assess psychological distress and its correlates in survivors of farmers' suicides. Methods: This was a cross-sectional study from two districts of Marathwada region of Maharashtra. A predesigned and pretested semi-structured questionnaire to assess sociodemographic variables was used. Self-reporting questionnaire-20 was administered to eval
Florinda F. Martins, Hélio Castro · 2020 · Energy Reports
Nowadays the production systems are linear and the consumption patterns are essentially based on products with a short life cycle, which contribute to increase the demand for raw materials and environmental impacts. The Circular Economy (CE) is playing a major role among scholars and practitioners. Many aspects are now defining this new trending paradigm such as the roles of product development, transformation and remanufacturing/recycling, and/or management of waste, ensuring the economic and environmental benefits. The increasing demand causes instability of the prices and markets, and there
Ines Farah KANFOUD, Ibrahim SERSAR, Meriem BENCHARIF et al. · 2026 · Revista Española de Nutrición Humana y Dietética
Introduction: Adopting good nutritional practices and strategies can be attributed to a better understanding of dietary knowledge and habits, thus promoting good sports performance. This study aimed to assess athletes' nutritional knowledge, eating habits, and adherence to the Mediterranean diet. Methodology: Cross-sectional survey of 70 adult athletes. Data were collected using a questionnaire assessing their eating habits, nutritional knowledge (Abridged Nutrition for Sport Knowledge Questionnaire, A-NSKQ), and adherence to the Mediterranean diet (Medi-Lite score). Statistical analyses were
Rika Kimoto, Isao Kambayashi, Akane Akizuki et al. · 2021 · Journal of Physical Fitness and Sports Medicine
The autonomic nervous system (ANS) maintains homeostasis through the balance of the sympathetic and parasympathetic subsystems or divisions. Currently, analysis of heart rate variability (HRV) offers an indirect, non-invasive assessment of ANS function. An irregular lifestyle and stress are known to affect ANS balance, influencing many diseases. Moreover, ANS disorder plays an important role in climacteric symptoms in menopausal females. The purpose of this study was designed to assess the effects of yoga practice sessions (herein referred to as “yoga”) on ANS function and focused on the relat
Kavita Hotwani, Krishna Sharma, Arpan Jaiswal · Dental Press Journal of Orthodontics
ABSTRACT Objective: The present study was an attempt to investigate tongue/mandible volume ratio in children, using volumetric magnetic resonance imaging (MRI) for early screening and to aid in treatment planning. Methods: Volumetric evaluation of tongue volume/mandible volume ratio (TV/MV ratio) in children with obstructive sleep apnea (OSA) using MRI was carried out retrospectively on available DICOM MR images of children in the age group of 10-14 years. MRI image records of patients diagnosed with OSA were obtained from interventional radiology department records, at Sharad Pawar Dental Col
Tiara Sekar Ayudhipasha, Menik Herdwiyanti, Sedayu Sedayu · 2025 · GHMJ (Global Health Management Journal)
Background: West Java ranks the highest Province with Human Immunodeficiency Virus (HIV) case in 2023. An estimated 1.648 patients estimated receive antiretroviral therapy (ART). Kidney disease contributes mortality amongst people living with HIV/AIDS (PLWH). Tenofovir disoproxil fumarate (TDF)-based ART was associated as risk factor of kidney disorders, indicate by declining glomerular filtration rate (GFR). However, there is limited study whether kidney disease among PLWH were related to ART use in Indonesia. Aims: To determine correlation between duration of antiretroviral therapy and glome
Jennifer L. Reidy, Lisa O'Donnell, Frank R. Thompson III · 2015 · Wildlife Society Bulletin
ABSTRACT It is critically important to determine and understand relationships between endangered species populations and landscape and habitat features to effectively manage and conserve populations and the habitats they rely on. Several recent studies focused on the golden‐cheeked warbler (Setophaga chrysoparia), an endangered songbird that breeds exclusively in central Texas, USA, have used a reproductive index to link pairing and breeding success to various factors of interest. However, no field test has evaluated the performance of a reproductive index at estimating productivity of golden‐
Fithria Aldy, Gema Nazri Yanni, Jelita Siregar · 2024 · Majalah Kedokteran Bandung
Myopia is the most common ophthalmic condition worldwide, with an estimated 22.9% of the population or 1.406 billion people affected. Studies of candidate gene-associated refraction abnormalities have also identified several genes that cause vulnerability myopia, including the hepatocyte growth factor (HGF) and hepatocyte growth factor receptor (MET) genes. The purpose of the study was to analyze the correlation between hepatocyte growth factor (HGF) levels, degrees of myopia, and long axial in adolescents with myopia treated as outpatients in Universitas Sumatera Utara Hospital. This study ap