A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20289 results in Negative / Null Result Report · page 662 of 677
Gulmez, Hinduja, Ajredini et al. · 2026 · International journal of colorectal disease
Redo/revisional ileal pouch-anal anastomosis (IPAA) surgery is technically challenging and more likely to require mesenteric lengthening maneuvers, largely due to mesenteric reach issues, which may affect the perfusion of the critical…
Hagita, Miura, Shirasuna et al. · 2026 · Animal science journal = Nihon chikusan Gakkaiho
This study examined the impact of early postpartum uterine oxidative stress and antioxidant activity on subsequent reproductive performance in lactating Holstein-Friesian dairy cows. Uterine flush fluid samples were collected at…
Majumder, Smyrnova, Ducharme · 2026 · The Journal of asthma : official journal of the Association for the Care of Asthma
The efficacy of inhaled corticosteroids (ICS) as prodrugs (inactive at delivery) has been compared to activated ICS, in mean changes in lung function and symptoms, with limited evidence on achieving control. We aimed to compare the…
Lv, He, Feng et al. · 2026 · The Journal of international medical research
ObjectiveUltrasound-guided percutaneous renal biopsy is a common diagnostic tool for renal disease. This study investigated the safety and efficiency of free-hand and puncture attachment approaches for ultrasound-guided percutaneous renal…
Nascimbene, Tosun, Nathan et al. · 2026 · Perfusion
BackgroundVeno-arterial extracorporeal membrane oxygenation (V-A ECMO) is used for refractory cardiogenic shock, yet optimal weaning strategies and the role of left ventricular (LV) venting remain unclear. The TWEET-1 study was designed as…
Kanazawa, Tominaga, Tanaka et al. · 2026 · Digestion
Ulcerative colitis (UC) is characterized by continuous inflammation extending from the rectum. Even mild inflammation can present prognostic implications when the disease is extensive. Mayo Endoscopic Score (MES) 1 represents increased…
Kamagaté, Jusot, Mory et al. · 2026 · Therapeutic advances in drug safety
In Côte d'Ivoire, pharmacovigilance is not a routine activity in most healthcare facilities and many healthcare professionals have limited knowledge of pharmacovigilance methods. This study aimed to evaluate the quality of adverse…
Saeed, Jalal · 2026 · Pulmonary medicine
The COVID-19 pandemic, caused by SARS-CoV-2, has led to significant global mortality and morbidity. Angiotensin-converting Enzyme 2 (ACE2) has been identified as the primary receptor for viral entry into host cells and is believed to play…
Mohammed, Naser, Abozaid · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
Composite resin placement technique may influence marginal integrity, polymerization stress distribution, and long-term clinical performance of posterior restorations. This randomized controlled clinical trial evaluated the 24-month…
Niu, Bao, Zhao · 2026 · Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
This study aimed to systematically evaluate the efficacy and safety of different doses of domperidone (DOM) combined with esomeprazole (ESM) in the treatment of reflux esophagitis, providing a basis for precise clinical medication. This…
Shi, Yuan, Gao et al. · 2026 · Journal of neuroengineering and rehabilitation
Transcranial magnetic stimulation (TMS), as a non-invasive neurostimulation technique, modulates neural activity by applying electromagnetic fields to specific areas of the brain. It is clinically used for several approved indications,…
Yakıt Yeşilyurt, Birinci Olgun, Dağ et al. · 2026 · BMC women's health
Breathing exercises may modulate dysmenorrhea by enhancing relaxation and eliciting analgesic effects. This study investigated the effects of Pelvic Floor Muscle Training (PFMT) with or without Dynamic Neuromuscular Stabilization…
Chen, Song, Zang et al. · 2026 · BMC anesthesiology
Right lateral thoracotomy cardiac surgery induces postoperative atelectasis due to cardiopulmonary bypass (CPB), patient positioning, and mechanical ventilation. Fixed positive end-expiratory pressure (PEEP) may fail to meet pediatric…
Yıldız, Çalış, Dokuz et al. · 2026 · Psychiatry research
This study examined differences in choroidal structural parameters, including the choroidal vascularity index, among patients with schizophrenia, bipolar disorder, and healthy controls. This cross-sectional study included 40 patients with…
Chen, Yi, Cao et al. · 2026 · Neurology
The efficacy of endovascular treatment for acute large vessel occlusion strokes has been demonstrated, but whether it can improve functional outcomes in patients with acute ischemic stroke (AIS) who only present with severe large vessel…
Bejarano, Hull, Young et al. · 2026 · PloS one
We exploit state-level policy changes for physical therapy direct access to estimate the effect of enacting direct access physical therapy policy on per-capita opioid pill volume (PCPV) and opioid-related deaths (ORD) compared to states…
Çınar, Uysal, Gürbüz et al. · 2026 · RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
This study aimed to investigate morphological features on magnetic resonance cholangiopancreatography (MRCP) that may help distinguish benign from malignant causes of isolated main pancreatic duct (MPD) dilation detected without a visible…
Li, Hu, Sun et al. · 2026 · The Journal of organic chemistry
Boron neutron capture therapy (BNCT) is a promising radiotherapeutic strategy for cancer treatment that selectively eradicates tumor cells while minimizing damage to surrounding healthy cells. 4-Borono-2-[ 18 F]fluoro-l-phenylalanine ([ 18…
Tang, Mi, Xue et al. · 2026 · Annals of medicine
The impact of prior SARS-CoV-2 infection on the clinical course of recurrent pulmonary tuberculosis (TB) remains poorly defined. This study aimed to compare clinical features, radiographic evolution, and outcomes in recurrent TB patients…
Wang, Guo · 2026 · The Journal of craniofacial surgery
To investigate the growth and developmental characteristics of the temporomandibular joint (TMJ) in adolescents with facial asymmetry and its relationship with mandibular morphological changes. A total of 20 patients aged 8 to 20 years…
Stewart, Yeo · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)
To compare the refractive prediction accuracy of two modern toric intraocular lens power formulas, using predicted or measured posterior corneal astigmatism, in eyes with a history of previous myopic laser vision correction (LVC). This…
Boben, Vangala, Maraka et al. · 2026 · Cureus
Introduction Accurate assessment of interarch tooth-size relationships is essential for orthodontic diagnosis, space analysis, and treatment planning. Bolton's analysis and regression-based methods such as Tonn's and Abhi's formulas are…
Zhang, Chen, Chen et al. · 2026 · Chinese medical journal
This is a multicenter, randomized, double-blind, placebo-controlled interventional clinical study to evaluate the efficacy and safety of pronase in improving visibility in colonoscopy and to evaluate whether pronase can increase the…
Liu, Liu, Zhang et al. · 2026 · Journal of cardiothoracic surgery
To observe the effect of hemoadsorption, an emerging therapy potentially valuable in blood purification, inflammation inhibition and toxic removal, to patients with Stanford Type A Aortic Dissection. The clinical data of 100 patients with…
Liu, Lv, Li et al. · 2026 · BMC oral health
Clear aligner fit accuracy significantly influences treatment efficacy. Micro-computed tomography (micro-CT) enables precise three-dimensional quantification of aligner-tooth adaptation, but manual measurement is time-intensive and…
Kotanlı, Yılmaz, Dogan · 2026 · BMC oral health
The aim of this retrospective study is to evaluate the volumetric and histogram-based characteristics of the parotid and submandibular salivary glands in patients with hypertension compared with healthy controls. Magnetic Resonance images…
Székely, Szabó, Kardos et al. · 2026 · Ideggyogyaszati szemle
The COVID-19 pandemic has had a complex impact on the incidence of spinal fractures. In 2020, Luigi di Filippo et al. published a surprising retrospective monocentric (in Milan) clinical study. X-rays of 114 COVID-19 infected pneumonia…
Kumar, Varghese, Pai et al. · 2026 · Indian journal of palliative care
Head-and-neck cancer (HNC) survivors undergoing concurrent chemoradiotherapy frequently experience treatment-related impairments such as trismus, cervical and shoulder dysfunction, and masticatory muscle weakness. This study aimed to…
Zhou, Ge, Jin et al. · 2026 · Frontiers in medicine
To evaluate the short-term effectiveness and safety of Phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy (PEI-GSL-GT) in eyes with prior failed trabeculectomy compared to surgically…
Qiu, Chen · 2026 · Frontiers in pediatrics
This research aims to investigate the performance of macrolide antibiotics for the treatment of Mycoplasma pneumoniae pneumonia (MPP) in children with or without Mycoplasma pneumoniae (MP) resistance genes. This retrospective study…