Negative / Null Result ReportOpen accessMedicine
Zhao Jiandong, Yuan Yongyi, Chen Jing et al. · 2012 · Journal of Translational Medicine
Abstract Background Many patients with enlarged vestibular aqueduct (EVA) have either only one allelic mutant of the SLC26A4 gene or lack any detectable mutation. In this study, multiplex ligation-dependent probe amplification (MLPA) was used to screen for copy number variations (CNVs) of SLC26A4 and to reveal the pathogenic mechanisms of non-syndromic EVA (NSEVA). Methods Between January 2003 and March 2010, 923 Chinese patients (481 males, 442 females) with NSEVA were recruited. Among these, 68 patients (7.4%) were found to carry only one mutant allele of SLC26A4 and 39 patients (4.2%) lacke
View details →DOI: 10.1186/1479-5876-10-82 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Takumi Osawa, Hitoshi Mori, Akane Kawai et al. · 2022 · Journal of Arrhythmia
Abstract Background Uninterrupted dabigatran during atrial fibrillation (AF) ablation is now established as the standard therapy. However, there are few reports on the effects of uninterrupted dabigatran on the intensity of anticoagulation during AF ablation. Methods We retrospectively analyzed 247 consecutive patients who underwent AF ablation in our hospital from January 2017 to December 2018. Patients who took warfarin or uninterrupted direct oral anticoagulants (DOACs) except for dabigatran were excluded. 89 patients underwent ablation with uninterrupted dabigatran (uninterrupted group, ma
View details →DOI: 10.1002/joa3.12655 Negative / Null Result ReportOpen accessDentistry
Hamed Kalhor, Mamak Adel, Maryam Tofangchiha et al. · 2026 · Annali di Stomatologia
Objectives: This study aimed to assess the effect of a metal artifact removal (MAR) algorithm on the visibility of the second mesiobuccal canal (MB2) of maxillary molars on cone-beam computed tomography (CBCT) scans. Materials and Methods: This cross-sectional study evaluated 41 CBCT scans of patients retrieved from the radiology clinic’s archives. The CBCT scans were saved with and without the MAR algorithm applied. The images were coded and evaluated by two endodontists to assess MB2 detection in maxillary molars and its visibility level using a 5-point Likert scale. Of the 164 samples, 32 w
View details →DOI: 10.59987/ads/2026.1.220-227 Negative / Null Result ReportOpen accessInternal medicine
LI Wen-hong, WANG Jin-wen, CHEN Hao et al. · 2015 · Linchuang shenzangbing zazhi
Objective To study the clinical curative effectiveness of high frequency ultrafiltration for the renal edema with diuretic resistance.Methods We selected 42 cases of nephrotic syndrome with severe edema.Among them,there were 20 cases of diabetic kidney disease,10 cases of lupus nephritis,8 cases of refractory primary nephrotic syndrome,and 4 cases of multiple myeloma nephropathy.All patients were subjected to standard treatment for 3-5 days according to different primary diseases after admission.Their urine was less than 800 mL every day and it met the standard of diuretic resistance.Then the
Negative / Null Result ReportOpen accessOphthalmology
Ritu Mali, Smruti R. Priyadarshini, Srikant K. Sahu et al. · 2024 · Indian Journal of Ophthalmology
Purpose: To compare the visual outcomes, postoperative complications, and graft asymmetry between precut and manually dissected donor tissues for Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet stripping endothelial keratoplasty (DSEK) procedures, respectively. Methods: Seventy eyes of 70 patients undergoing DSEK/DSAEK at a tertiary eyecare center in eastern India were included in this prospective randomized control study. The 70 eyes were divided equally into two groups. Group A (n = 35) and Group B (n = 35) underwent DSEK and DSAEK procedures, respectively. the ope
View details →DOI: 10.4103/ijo.ijo_3282_23 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Amira Al Balakosy, Mostafa Alfishawy, Omnia Elnabawy et al. · 2021 · Afro-Egyptian Journal of Infectious and Endemic Diseases
Background and study aim: Epidemiological data reported lower death rates of COVID-19 cases in countries with higher & recent coverage by measles containing vaccines. In this study we aim to identify measles IgG titer in COVID-19 patients & correlate it with disease severity. Patients and Method: This is a Cross-sectional study where 78 patients admitted to Ain Shams University Quarantine hospitals with positive PCR for SARS-CoV-2 were enrolled. All patients underwent quantification of serum measles IgG titer. Then classified according to the COVID-19 severity into mild, moderate and
View details →DOI: 10.21608/aeji.2021.72615.1144 Negative / Null Result ReportOpen accessMedicine
fatemeh marhemati, reza mir arab razi, mostafa azizi · 2020 · آموزش پزشکی
Background and Objective: Creating and developing self-directed learning skills has become one of the goals of education in recent decades, and today's students need to learn and acquire comprehensive information in this regard, or better to say, learn information and communication technology skills, to Be able to use electronic services. The purpose of this study was to investigate the relationship between electronic citizenship knowledge and self-directed learning of students of University of Mazandaran and Babol University of medical sciences. Methods: This study is descriptive-analytical i
Negative / Null Result ReportOpen accessPediatrics
Roberto Teggi, Bruno Colombo, Marco Familiari et al. · 2023 · Frontiers in Pediatrics
IntroductionVestibular impairment and vertigo in the pediatric population have an estimated prevalence ranging between 0.4% and 5.6% and are a topic of interest in recent years. The Bárány Society has recently reclassified migraine-related vertigo syndromes as vestibular migraine of childhood (VMC), probable vestibular migraine of childhood (probable VMC), and recurrent vertigo of childhood (RVC).MethodsApplying the criteria established by the Bárány Society, we retrospectively analyzed data on 95 pediatric patients suffering from episodic vertigo that were recruited from 2018 to 2022. In appl
View details →DOI: 10.3389/fped.2023.1152928 Negative / Null Result ReportOpen accessGynecology and obstetrics
Fedora Ambrosetti, MD, Giovanni Grandi, MD, Elisabetta Petrella, MD et al. · 2023 · AJOG Global Reports
BACKGROUND: The use of epidural analgesia represents the gold standard for pain management during labor, but the influence of the use of epidural analgesia on delivery mode is not fully understood. OBJECTIVE: This study aimed to analyze the impact of epidural analgesia on the delivery mode, namely, cesarean delivery, vaginal delivery, and operative vaginal delivery rates, in Robson class 1 women. STUDY DESIGN: A retrospective cohort study was conducted on all Robson class 1 women who delivered from January 1, 2019, to December 31, 2019, in the University Hospital of Modena. The primary outcome
View details →DOI: 10.1016/j.xagr.2023.100207 Negative / Null Result ReportOpen accessSports medicine
JL Ayers, M DeBeliso, TG Sevene et al. · 2016 · Biology of Sport
Olympic weightlifting movements and their variations are believed to be among the most effective ways to improve power, strength, and speed in athletes. This study investigated the effects of two Olympic weightlifting variations (hang cleans and hang snatches), on power (vertical jump height), strength (1RM back squat), and speed (40-yard sprint) in female collegiate athletes. 23 NCAA Division I female athletes were randomly assigned to either a hang clean group or hang snatch group. Athletes participated in two workout sessions a week for six weeks, performing either hang cleans or hang snatc
View details →DOI: 10.5604/20831862.1201814 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Alsubaie SS · 2025 · Neuropsychiatric Disease and Treatment
Sultan Saad Alsubaie Department of Psychiatry, Armed Forces Hospital, Khamis Mushayt, Saudi ArabiaCorrespondence: Sultan Saad Alsubaie, Consultant Psychiatrist, psychiatry department, Armed Forces Hospital Southern Region, P.O. Box 101, Khamis Mushayt, Saudi Arabia, Tel +96-6503799971, Email dr.slt4444@gmail.comPurpose: This study aims to compare self-esteem and social anxiety disorder (SAD) symptoms levels between visually impaired and sighted individuals, and to explore the relationship between social anxiety and various sociodemographic factors.Materials and Methods: A case-control study wa
Negative / Null Result ReportOpen accessAnimal culture
P. P. Singh, Ashok Kumar, R. S. Chauhan et al. · 2016 · Veterinary World
Aim: The present study was aimed to investigate the immunological competence of chlorpyrifos (CPF) insecticide after oral administration in layer chickens. Materials and Methods: A total of 20 White Leghorn birds were given CPF in drinking water at 0.3 ppm/bird/day (no observable effect level dose) for a period of 3-month. Immune competence status of layer birds and chicks hatched from CPF-treated birds were estimated at 15 days interval in layer birds and monthly interval in chicks using immunological and biochemical parameters. Results: There was a significant decrease in values of total leu
View details →DOI: 10.14202/vetworld.2016.753-758 Negative / Null Result ReportOpen accessSurgery
Ahmet Adnan Cırık, Yeşim Esen Yiğit, Ahmet Mahmut Tekin et al. · 2024 · Frontiers in Surgery
PurposeThis study aimed to assess the readability indices of websites including educational materials on otosclerosis.MethodsWe performed a Google search on 19 April 2023 using the term “otosclerosis.” The first 50 hits were collected and analyzed. The websites were categorized into two groups: websites for health professionals and general websites for patients. Readability indices were calculated using the website https://www.webfx.com/tools/read-able/.ResultsA total of 33 websites were eligible and analyzed (20 health professional-oriented and 13 patient-oriented websites). When patient-orie
View details →DOI: 10.3389/fsurg.2024.1327793 Negative / Null Result ReportOpen accessMedicine
Justin Fulkerson, MSN, Robert Lowe, BSN, Tristan Anderson, BSN et al. · 2016 · Western Journal of Emergency Medicine
Introduction: This study compared the effects of vasopressin via tibial intraosseous (IO) and intravenous (IV) routes on maximum plasma concentration (Cmax), the time to maximum concentration (Tmax), return of spontaneous circulation (ROSC), and time to ROSC in a hypovolemic cardiac arrest model. Methods: This study was a randomized prospective, between-subjects experimental design. A computer program randomly assigned 28 Yorkshire swine to one of four groups: IV (n=7), IO tibia (n=7), cardiopulmonary resuscitation (CPR) + defibrillation (n=7), and a control group that received just CPR (n=7).
View details →DOI: 10.5811/westjem.2015.12.28825 Negative / Null Result ReportOpen accessMedicine (General)
Zhen Yu Jia, Yuan Yuan Jiang, Jung Min Woo et al. · 2018 · Neurointervention
Purpose Wide-neck aneurysms (WNAs) associated with a dilated parent artery (PA) are not uncommon morphological abnormalities and usually cause inappropriate wall apposition and incomplete neck coverage of a tubular stent in stent-assisted coiling of aneurysms. We aimed to introduce a fusiform-shaped stent (FSS) and test its effectiveness in treating intracranial WNAs associated with a dilated PA using a three-dimensional (3D) model. Materials and Methods Two FSS types were designed with the middle one-third segment dilated by 10% (FSS10) and 20% (FSS20) and were compared with the tubular-shape
View details →DOI: 10.5469/neuroint.2018.00976 Negative / Null Result ReportOpen accessPublic aspects of medicine
Said Kara · 2022 · Journal of Public Health in Africa
Background. The purpose of this study was to investigate the connection between self-efficacy and treatment adherence, working on the assumption that self-efficacy plays a role in determining treatment adherence in chronic diseases. Hypertension affects one-third of the world’s population. In Africa, hypertension is a leading cause of death from a non-communicable disease. Modifications to lifestyle and behavior, as well as increased access to pharmaceuticals, are necessary for every African nation to bring the prevalence of hypertension and cardiovascular disorders under control. Methods. In
View details →DOI: 10.4081/jphia.2022.2121 Negative / Null Result ReportOpen accessInternal medicine
Ovcaric Mick, Lea Rod, Sundholm James et al. · 2005 · BMC Medical Genetics
Abstract Background Migraine is a polygenic multifactorial disease, possessing environmental and genetic causative factors with multiple involved genes. Mutations in various ion channel genes are responsible for a number of neurological disorders. KCNN3 is a neuronal small conductance calcium-activated potassium channel gene that contains two polyglutamine tracts, encoded by polymorphic CAG repeats in the gene. This gene plays a critical role in determining the firing pattern of neurons and acts to regulate intracellular calcium channels. Methods The present association study tested whether le
View details →DOI: 10.1186/1471-2350-6-32 Negative / Null Result ReportOpen accessDentistry
Hakan Türkkahraman, Cenker Küçükeşmen · 2005 · Turkish Journal of Orthodontics
The aim of our study was to compare shear bond strengths of orthodontic brackets bonded with chemically cured, halogen light cured and LED cured adhesive systems. 45 extracted human premolar teeth were randomly divided into 3 groups. Bicuspid metal brackets were bonded on first group of teeth with chemically cured bonding system (Rely-a-Bond). Second group were bonded with halogen light cured bonding system (Light Bond). Last group were bonded with LED light cured bonding system (Light Bond). Each specimen was then loaded to universal testing machine. Bond strength was determined in the shear
View details →DOI: 10.13076/1300-3550-18-1-5 Negative / Null Result ReportOpen accessOrthopedic surgery
Ameya S. Kamat · 2011 · Advances in Orthopedics
Aims. Emergency debridement has long been the standard of care for open fractures of the tibia as infection is an important complication. The timing of operative debridement can be debated. We review open fractures of the tibia and compare infection rates in those that were operated on within and after 6-hours. Method. 103 consecutive open fractures of the tibia were reviewed. The data was analysed retrospectively with regard to severity of fracture and incidence of infection. Infection rates over a three-month period were compared between the two groups. Results. 12 (11.6%) patients developed
View details →DOI: 10.4061/2011/943495 Negative / Null Result ReportOpen accessMedicine
Jun Seok Lee, Ah Ra Jung, Jung Min Park et al. · 2018 · Clinical and Experimental Otorhinolaryngology
Objectives To analyze laryngopharyngeal reflux (LPR) as an acidic, nonacidic, or mixed type according to 24-hour multi-channel intraluminal impedance (MII) pH monitoring and the clinical characteristics of each type. Methods Ninety patients were prospectively enrolled in this study. All patients underwent 24-hour MII pH monitoring as a diagnostic tool. Eighty-three patients were diagnosed with LPR. The patients were classified into three groups according to the pH of the hypopharyngeal probe: the acid reflux group, nonacid reflux group, and mixed reflux group. Subjective symptoms and objective
View details →DOI: 10.21053/ceo.2017.00577 Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Ye Sheng, Xiaobo Fu, Guobao Wang et al. · 2023 · Cancer Imaging
Abstract Background Several previous studies demonstrated that the combination of self-expandable metallic stents (SEMS) and 125I seed implantation might prolong stent patency and obtain survival benefits for malignant obstructive jaundice (MOJ) patients. However, these studies rarely mentioned a comparison between CT-guided intratumoral 125I seed implantation and intraluminal 125I seed strand insertion combined with stenting for the management of MOJ. This study aimed to further evaluate the safety and efficacy of SEMS combined with 125I brachytherapy in the management of unresectable MOJ. Me
View details →DOI: 10.1186/s40644-023-00551-0 Negative / Null Result ReportOpen accessBiochemistry
Li Jiaohui, Zhong Chengyun, Bian Guanji · 2025 · Journal of Medical Biochemistry
Background: Epilepsy is a prevalent neurological disorder, and evaluating its treatment strategies is highly significant. This study aimed to compare the effects of monotherapy with carbamazepine and levetiracetam on the results of coagulation tests, including prothrombin time, activated partial thromboplastin time, fibrinogen, and D-dimer levels, as well as on seizure control in patients with partial-onset epilepsy. Methods: A total of 89 patients diagnosed with POE and treated at our hospital between January 2023 and January 2024 were enrolled. The patients were divided into the carbamazepin
View details →DOI: 10.5937/jomb0-52052 Negative / Null Result ReportOpen accessNuclear engineering. Atomic power
Junhyuk Jang, Minsoo Lee, Gha-Young Kim et al. · 2025 · Nuclear Engineering and Technology
Copper oxidation at low temperatures below 140 °C and its effects on corrosive behavior in aerobic groundwater are investigated to estimate the intactness of canisters at early stages of disposal. The Cu coupon surface is covered by fine particles that form thin oxide layers after 30 d of oxidation; a thin Cu2O layer of thickness <100 nm is formed after oxidation at 40 °C; after oxidation at 140 °C, the Cu2O surface changes to a CuO layer of thickness <500 nm. The thickness of the Cu surface oxidized at 90 °C is between those of the surfaces oxidized at 40 and 140 °C. All Cu coupons exhibit si
View details →DOI: 10.1016/j.net.2024.08.012 Negative / Null Result ReportOpen accessMedicine
Zainab Y. Ejam, Şevki Adem, Asmaa Kadhim Gatea · 2024 · Medical Journal of Babylon
Background: Vascular endothelial growth factor (VEGF) is crucial for the implantation of a fertilized egg and for the development of placental blood vessels. This study was conducted to detect the serum VEGF level of pregnant with different types of assisted reproductive techniques in relation to the age group, body mass index (BMI), and type of infertility. Objectives: The aim of this study was to determine the levels of serum VEGF in different types of assisted pregnancy. Materials and Methods: Enzyme-linked immunosorbent assay was used for the detection of VEGF levels in the serum of pregna
View details →DOI: 10.4103/mjbl.mjbl_1495_23 Negative / Null Result ReportOpen accessSports medicine
Iraj Hoseinzade, Ahmad Abdi, Asieh Abbassi Daloii · 2022 · فیزیولوژی ورزش و فعالیت بدنی
Background and Purpose: Fat tissue, frequently the largest organ in humans, is at the nexus of mechanisms involved in longevity and age-related metabolic dysfunction. Fat distribution and function change dramatically throughout life. Obesity is a major risk factor for development of comorbidities such as type-2 diabetes, neurological disorders, osteoarthritis, cancer, cardiovascular and renal diseases, which is associated with increased senescent cell and heart disorders. Exercise training and natural supplements constitute an indispensable, tool in the management of obesity and obesity-relate
View details →DOI: 10.52547/joeppa.15.3.91 Negative / Null Result ReportOpen accessBiotechnology
Tomáš Svoboda, Daniel Ruman, Milan Gaff et al. · 2015 · BioResources
The influence of selected factors, such as wood species, veneer combinations, and loading cycles, on the bending strength and modulus of elasticity of glued laminated wood was investigated after cyclic loading of 0, 1000, 3000, and 7000 cycles with European beech (Fagus sylvatica (L.)) and Eurasian aspen (Populus tremula (L.)) The laminated woods were created by a combination of densified and non-densified veneers. The 30% densification was carried out by cold rolling. All factors and their interactions had statistically significant influence on the modulus of elasticity. Similarly, the influe
View details →DOI: 10.15376/biores.10.4.8461-8473 Negative / Null Result ReportOpen accessVeterinary medicine
Tytti Maaria Niemelä, Riitta-Mari Tulamo, Jorge Uriel Carmona et al. · 2019 · Acta Veterinaria Scandinavica
Abstract Background Inflammatory and degenerative activity inside the joint can be studied in vivo by analysis of synovial fluid biomarkers. In addition to pro-inflammatory mediators, several anabolic and anti-inflammatory substances are produced during the disease process. They counteract the catabolic effects of the pro-inflammatory cytokines and thus diminish the cartilage damage. The response of synovial fluid biomarkers after intra-articular hyaluronan injection, alone or in combination with other substances, has been examined only in a few equine studies. The effects of hyaluronan on som
View details →DOI: 10.1186/s13028-019-0460-6 Negative / Null Result ReportOpen accessPharmacy and materia medica
Saeid Abbasi-Maleki, Hadi Yousefi*, Rahim Sharafkhani et al. · 2023 · Research Journal of Pharmacognosy
Background and objectives: Earlier researches have exhibited the antioxidant, antinociceptive, and antiepileptic effects of Ferula gummosa. Considering that antioxidants play a key role in the pathogenesis of depression, the antidepressant potential of the F. gummosa essential oil was assessed by using a mouse models. Methods:Lorke’s method was used to access the acute toxicity of the F. gummosa essential oil. The F. gummosa essential oil (5-40 mg/kg), standard agents, and vehicle were administered to animals. The forced-swimming test (FST), tail suspension test (TST), and open-field test (OFT
View details →DOI: 10.22127/rjp.2023.371172.2083 Negative / Null Result ReportOpen accessFood processing and manufacture
N. M. Yushchenko, Yu. V. Shevchuk · 2024 · Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького. Серія: Харчові технології
Today, diseases that cause intolerance to food ingredients in the composition of traditional food products are spreading rapidly in the civilized world. Therefore, the current direction of scientific research is the scientific and practical substantiation of the technologies of food products with multifunctional properties, which will ensure complete nutrition of the most vulnerable categories of society – with intolerance to gluten, milk proteins, and egg white, lactase deficiency, insulin resistance, and prediabetic conditions, etc. The selection of non-traditional raw materials was carried
View details →DOI: 10.32718/nvlvet-f10104 Negative / Null Result ReportOpen accessMicrobiology
Tangolar Semih, Tarım Güzin, Kelebek Haşim et al. · 2015 · BIO Web of Conferences
This study aims at assessing the effects of increased bud load and irrigation applications on berry quality of the Razakı table grape. Two Regulated Deficit Irrigation (RDI) having different irrigation levels (RDI-I and RDI-II) based on the growth stages, in addition to a non-irrigated control treatment together with two different bud load practices (K-normal and 2K-two-fold buds of the normal) were examined for their effects on quality attributes such as sugar and organic acids contents, phenolic compounds as well as antioxidant capacity of the berries. The non-irrigated vines had highest sug
View details →DOI: 10.1051/bioconf/20150501002 