A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20289 results in Negative / Null Result Report · page 654 of 677
Mallus F, Yang Y, Kia SM et al. · 2026 · Preprint
Abstract Spectral features derived from electroencephalography (EEG) have long been proposed as biomarkers of brain dysfunction, yet few have gained consensus or entered clinical practice. A key obstacle is the lack of harmonized,…
Gottfried JA, Shen C, Morgan D et al. · 2026 · Optics express
In a previous publication [Opt. Express21, 28182 (2013)10.1364/OE.21.028182], Daido et al . reported that solid samples of metallic sodium exhibited high transparency of vacuum ultraviolet light through several millimeter-thick samples.…
Azaad S, Laham S, Sebanz N · 2026 · Preprint
Evidence from joint action research suggests that a suite of spontaneous cognitive and perceptual processes underpins our ability to coordinate with others. We tested whether people spontaneously perceive affordances (or action…
Weber S, Kemp SA, Hinder MR · 2026 · Cognitive, affective & behavioral neuroscience
Action cancellation represents a fundamental aspect of human motor control. Nonetheless, the behavioural paradigms used to study it are methodologically diverse and capture an incompletely understood combination of processes. Advancing…
Macaulay C, Scheepers C · 2025 · Preprint
A Theory of Magnitude (AToM) (Walsh, 2003; Walsh, 2014) attempts to explain avisuo-spatial bias observed across magnitude processing domains (e.g., numerical, temporal).It proposes a generalised processing system which maps mental…
Van der Snickt T, Ailliet S, Bassini S et al. · 2025 · Preprint
Enzyme-free isothermal amplification methods offer a promising alternative to enzymatic assays for nucleic acid detection, particularly in low-resource settings. The nonenzymatic isothermal strand displacement and amplification (NISDA)…
Walleczek J, von Stillfried N, Schmidt S et al. · 2025 · Preprint
This metascientific project studied the replicability of Bem Experiment 1, which had claimed a precognitive effect, i.e., the ability to successfully guess the outcome of future random events (Bem. J Pers Soc Psychol. 2011;100: 407-25).…
Li L, Wang Y, Du Z et al. · 2026 · Metabolism: clinical and experimental
Background and aims Targeting key enzymes in hepatic de novo lipogenesis (DNL) presents a promising strategy for treating hypercholesterolemia. However, the precise regulatory mechanisms governing hepatic DNL remain incompletely…
Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in veterinary science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
Willroth EC, Young G, Ford BQ et al. · 2025 · Psychological science
Certain emotion-regulation strategies (e.g., reappraisal) are associated with better well-being and are therefore seen as adaptive (health-promoting) strategies. However, it is unlikely that any strategy is adaptive regardless of context.…
Argenbright CM, Scully IF, Flores D et al. · 2025 · The journal of pain
Pain is a multidimensional phenomenon, encompassing affective-motivational, cognitive-evaluative, and sensory-discriminative domains. Understanding these components is crucial for effective diagnosis and management, particularly in…
Goldberg SB, Baldwin SA, Flynn AWP et al. · 2026 · Clinical psychological science : a journal of the Association for Psychological Science
While it is known that therapists vary in effectiveness, it is unclear what therapist-level characteristics predict this variation. We conducted a large-scale, preregistered study ( n = 97 therapists from the United States and Canada, n =…
Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…
Kakeya H, Umeno Y · 2025 · Preprint
Background Kayano et al. estimated the potential number of COVID-19 cases and deaths in Japan from February 17 to November 30, 2021, in a counterfactual scenario where no vaccination was implemented. Their model predicted 63.3 million…
Stawiany K, Kozak K, Sokołowska Z · 2025 · Preprint
The study explores the hypothesis that individuals show greater sympathy towards coherent name-face pairs compared to incoherent pairs, replicating the effect observed by Barton and Halberstadt. A structured questionnaire was designed…
Houben M, Rief W, Gärtner T et al. · 2024 · Preprint
Abstract Background: Depression is related to a reduced update of negative expectations in response to positive information. Here, we aimed to replicate that cognitive immunization (a cognitive devaluation of expectation-disconfirming…
Whiteford KL, Baltzell LS, Chiu M et al. · 2024 · Preprint
Musical training has been associated with enhanced neural processing of sounds, as measured via the frequency following response (FFR), implying the potential for human subcortical neural plasticity. We conducted a large-scale multi-site…
Zhou Y, Tse CS · 2025 · The Journal of general psychology
In English, head is associated with rationality and logic, whereas heart is related to feeling and emotionality. In Chinese, these head- and heart-related metaphors also exist. Could these head- and heart-related conceptual metaphors…
Noel M, Suttapitugsakul S, Cummings RD et al. · 2024 · Preprint
Protein O-glycosylation is a critical modification in the brain, as genetic variants in the pathway are associated with both common and severe neuropsychiatric phenotypes. However, little is known about the most abundant type of O-glycan…
Stüber AT, Heimer MM, Ta J et al. · 2025 · European journal of radiology
This study investigates the predictive capability of radiomics in determining programmed cell death ligand 1 (PD-L1) expression (>=1%) status in non-small cell lung cancer (NSCLC) patients using a newly collected [18F]FDG PET/CT dataset.…
Centorame G, Warrington NM, Hemani G et al. · 2024 · Preprint
Background Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids (LC-PUFA), which are essential for brain development. In 2007, Caspi et al. found evidence in…
Wiesing M, Zimmermann E · 2023 · Preprint
Intentional actions produce a temporal compression between the action and its outcome, known as intentional binding. However, Suzuki et al. (2019) recently showed that temporal compression can be observed even without intentional actions.…
Lloyd B, Wurm F, de Kleijn R et al. · 2023 · Preprint
Background Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising brain stimulation method for the treatment of pharmaco-resistant epilepsy and depression. Its clinical efficacy is thought to depend on taVNS-induced…
Ahrens A, Liesefeld HR, Kinner J et al. · 2026 · Psychological research
In everyday life, we often generalize previously learned associations between our actions and their outcomes to novel, but similar situations. The present study aimed to conceptually and directly replicate results reported by Esser et al.…
Wentura D, Gurbuz E, Paulus A et al. · 2023 · Journal of experimental psychology. Human perception and performance
When asked to judge or react to a facial emotional display of a person, people do not only take the emotion into account, but also other socially important features of the face, such as, for example, ethnicity (Kozlik & Fischer, 2020;…
Aicoboaie S, Pappaianni E, Abdulkadir M et al. · 2025 · Psychological medicine
Background Shared genetic risk has been shown across psychiatric disorders. In particular, anorexia nervosa (AN), obsessive-compulsive disorder (OCD), and schizophrenia (SCZ) show shared genetic risk that matches clinical evidence of…
Bechtel GN, Kostelnik CJ, Rausch MK · 2025 · Journal of biomedical materials research. Part A
Tissue mimicking materials are designed to represent real tissue in applications such as medical device testing and surgical training. Thanks to progress in 3D-printing technology, tissue mimics can now be easily cast into arbitrary…
Saladini F, Giannini A, Giammarino F et al. · 2026 · Open forum infectious diseases
Background HIV-1 sub-subtype A6 is predominant in Eastern Europe and was associated with increased risk of treatment failure with the long-acting cabotegravir plus rilpivirine regimen. In this study, we aimed to evaluate the in vitro…
Hoth KF, Voorhies K, Wu AC et al. · 2022 · Journal of psychiatry and brain science
Depression is the most common mental illness in the U.S. affecting nearly 40 million adults age 18 years and older. Depression has both genetic and environmental influences. In addition, women are more likely to be affected by depression…
Fang J, Cao Y, Ni J · 2023 · Preprint
Background: Intracranial aneurysm (IA) accounts for a substantial source of non-traumatic subarachnoid hemorrhage, with inflammation postulated as a potential factor in its pathogenesis. The present study aims at evaluating the association…