Negative / Null Result ReportMedicine
Espinoza Ramirez J, Durango M, Santalo O et al. · 2026 · Journal of the American Pharmacists Association : JAPhA
Background Many organizations have developed criteria for pharmacy practice models; however, most of these models are not based on studies evaluating clinical outcomes. Currently, there is no consensus on the ideal pharmacy practice model.…
View details →DOI: 10.1016/j.japh.2026.103155 Negative / Null Result ReportMedicine
Chang YJ, Hsu TC, Chan CH et al. · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
ObjectiveTo evaluate 3-dimensional pharyngeal airway changes following 2-jaw orthognathic surgery in skeletal Class III patients and to assess their association with surgical movements.DesignRetrospective observational study.SettingSingle…
View details →DOI: 10.1177/10556656261463034 Negative / Null Result ReportMedicine
Shi K, Li J · 2026 · Psychological research
This study adopts the Think/No-Think (TNT) paradigm for the first time to examine whether activation of thematic semantic relation representations is intrusive. In Experiment 1, during the learning phase, participants memorized cue–target…
View details →DOI: 10.1007/s00426-025-02226-w Negative / Null Result ReportMedicine
Suematsu Y, Minei A, Sumita Y et al. · 2026 · European journal of preventive cardiology
Aims Cardiac rehabilitation (CR) has been shown to improve the prognosis of patients with acute myocardial infarction (AMI). In Japan, the duration of hospitalization has shortened, resulting in a lower participation rate in CR among…
View details →DOI: 10.1093/eurjpc/zwaf705 Negative / Null Result ReportMedicine
Omerovic E, Råmunddal T, Jha S et al. · 2026 · European heart journal. Cardiovascular pharmacotherapy
Two contemporary randomized trials of β-blocker therapy after myocardial infarction (MI) reached apparently conflicting conclusions. REBOOT, conducted in Spain and Italy, found no reduction in death or major cardiovascular events among…
View details →DOI: 10.1093/ehjcvp/pvag037 Negative / Null Result ReportMedicine
Mittal H, Thattaruthody F, Akella M et al. · 2026 · Indian journal of ophthalmology
Abstract This experiment was designed to study the effect of mitomycin C (MMC) on conjunctival lymphatics and the lymphangiogenesis potential of synthetic retinoic acid (ec23) in rat eyes. This prospective animal experimental study…
View details →DOI: 10.4103/ijo.ijo_1929_25 Negative / Null Result ReportMedicine
Royo M, Jiménez Á, Molina-Martin A et al. · 2026 · European journal of ophthalmology
PurposeTo analyze the amplitude of accommodation and its changes at a 6-month follow-up in healthy subjects implanted with an anterior chamber pIOL, assessing whether accommodative function is affected. Additionally, changes in visual…
View details →DOI: 10.1177/11206721261462300 Negative / Null Result ReportOpen accessMedicine
Temizel KA, Dursun P, Ikizoglu G · 2026 · Postepy dermatologii i alergologii
Introduction Chronic spontaneous urticaria (CSU) and urticarial vasculitis (UV) are chronic inflammatory skin disorders. Monoclonal anti-IgE therapy is widely approved for CSU and is increasingly investigated for its broader…
View details →DOI: 10.5114/ada.2026.161026 Negative / Null Result ReportOpen accessMedicine
Siqueira RC, Pinho TS, Brandao CC · 2026 · Cureus
Objective The objective of this study was to evaluate the short-term ocular safety, feasibility, and exploratory functional signals associated with intravitreal adalimumab (ADA) in patients with retinitis pigmentosa (RP). Methods This…
View details →DOI: 10.7759/cureus.109091 Negative / Null Result ReportMedicine
Nelles D, Özkan N, Vogelhuber J et al. · 2026 · Heart and vessels
To assess the impact of functional tricuspid regurgitation (FTR) and transcatheter tricuspid valve repair (TTVR) on sympathetic nerve activity (SNA). Increased SNA is associated with adverse outcomes and reduced survival in patients with…
View details →DOI: 10.1007/s00380-026-02719-7 Negative / Null Result Report
Nicolli A, Armani T, Buendía Arellano M et al. · 2026 · Preprint
Cryopreservation of ram semen induces structural and functional alterations that compromise sperm fertility. Since seminal plasma contributes to the regulation and preservation of sperm function, increasing attention has been directed…
View details →DOI: 10.64898/2026.06.17.732841 Negative / Null Result Report
Wahyono P, Ariesaka KM, Susetyarini E et al. · 2026 · Preprint
Background Limited male contraception choices have prompted the hunt for natural antifertility drugs. This experimental study investigates the antifertility effects of stigmasterol extracted from Pluchea indica leaves in male rats ( Rattus…
View details →DOI: 10.12688/f1000research.180671.2 Negative / Null Result ReportMedicine
Sun G, Lin W, Peng Y et al. · 2026 · BMC anesthesiology
Postoperative fatigue is a prevalent complication delaying early recovery after gynecological laparoscopic surgery, with no proven effective interventions. To investigate the effect of continuous intraoperative low-dose esketamine on…
View details →DOI: 10.1186/s12871-026-04051-z Negative / Null Result ReportOpen accessMedicine
Ciccarelli G, Monaco E, Nasso V et al. · 2026 · Journal of experimental orthopaedics
Purpose The purpose of this study was to quantify return-to-play (RTP) time, post-operative performance and market-value trends after proximal hamstring repair in top-tier European league soccer players. It was hypothesized that surgery…
View details →DOI: 10.1002/jeo2.70775 Negative / Null Result ReportMedicine
Deruelle P, Arcieri F, Martineau R · 2026 · Gynecologie, obstetrique, fertilite & senologie
Background Hyperemesis gravidarum (HG) remains one of the most disabling complications of the first trimester, with a high risk of recurrence after a prior episode that weighs heavily on family planning and on patients' mental health.…
View details →DOI: 10.1016/j.gofs.2026.06.002 Negative / Null Result ReportOpen accessMedicine
Pak K, Yoon C, Sadda SR · 2026 · Eye (London, England)
Purpose To evaluate longitudinal change in hard exudate (HEs) volume over 5-years following anti-VEGF treatment for diabetic macular oedema (DMO). Methods This study was a post-hoc analysis of structural optical coherence tomography (OCT)…
View details →DOI: 10.1038/s41433-026-04408-1 Negative / Null Result Report
Holgado D, Martínez-Pérez V, Martín-Arévalo E et al. · 2026 · Preprint
Inconsistent evidence regarding the cognitive effects of transcranial direct current stimulation (tDCS) highlights the need for more comprehensive approaches to assess its impact. This study aimed to investigate the effects of…
View details →DOI: 10.31234/osf.io/cbwt3_v4 Negative / Null Result ReportMedicine
Kim HSW, Cha S, Choi JY et al. · 2026 · The Journal of craniofacial surgery
This study compared the upper airway dimensions following maxillomandibular advancement (MMA) surgery in adults with obstructive sleep apnea (OSA) with those of normal controls. Korean adult OSA patients who underwent conventional MMA…
View details →DOI: 10.1097/scs.0000000000012731 Negative / Null Result ReportMedicine
Haflidadottir S, Helgadottir FD, Sighvatsson MB · 2026 · Scandinavian journal of psychology
The global burden of infertility and its associated psychological distress is substantial, yet many individuals face barriers to accessing psychological support. A scalable, low-cost online intervention presents a promising solution. A…
View details →DOI: 10.1111/sjop.70126 Negative / Null Result Report
Yu C, Huang W, Yu B et al. · 2026 · Preprint
Synthetic 6-Br-Q0C10 has been shown to have a partial electron transfer activity of native coenzyme Q in the isolated mitochondria. It reduces energy coupling efficiency by 30 %, suggesting that it may be useful in the management of…
View details →DOI: 10.64898/2026.05.23.723575 Negative / Null Result Report
May R, Hernández Gómez MÁ, Aguirre Martínez JL et al. · 2026 · Preprint
One of the most notable impacts of wind energy is bird mortality due to collisions with wind turbines, making it necessary to adopt measures to prevent or mitigate this impact. In recent years, studies have been carried out to test the…
View details →DOI: 10.22541/authorea.15003733/v1 Negative / Null Result ReportOpen accessMedicine
Leal Barbosa V, Westenhofen D, Scherdien Silva P et al. · 2026 · Lasers in medical science
Purpose To evaluate the efficacy of 8% arginine-based desensitizing toothpaste and photobiomodulation (PBM), used alone or in combination, in the treatment of dentin hypersensitivity (DH). Materials and methods This randomized,…
View details →DOI: 10.1007/s10103-026-04927-z Negative / Null Result Report
Baek JS, Lokhande A, Neuenschwander D et al. · 2026 · Preprint
Purpose To investigate the relative efficacy of nine distinct visual field (VF) denoising artificial intelligence (AI) methods and a pathology-aware AI strategy to discourage over-correction of glaucomatous defects. Design Retrospective…
View details →DOI: 10.64898/2026.05.29.26354019 Negative / Null Result ReportMedicine
van Lohuizen Q, Fransen SJ, Yiasemis G et al. · 2026 · European radiology
Objectives To determine whether AI-reconstructed prostate MRI at reduced acquisition times maintains prostate cancer (PCa) detection performance comparable to conventional scans. Materials and methods This multicenter, retrospective,…
View details →DOI: 10.1007/s00330-026-12479-7 Negative / Null Result ReportMedicine
Akay T, Arslan RS · 2026 · Scientific reports
Patients with deep perianal abscess (DPA) and transsphincteric fistula typically require incision and drainage as emergency treatment. However, recurrent abscesses and fistulas are common. This study aimed to evaluate the impact of…
View details →DOI: 10.1038/s41598-026-59144-z Negative / Null Result ReportMedicine
Verhulst E, Ten Broek R, Bislenghi G et al. · 2026 · Techniques in coloproctology
Postoperative intraabdominal adhesions remain one of the most common and clinically significant complications following abdominal and pelvic surgery. Adhesions contribute to adhesive small bowel obstruction (aSBO), chronic abdominal pain,…
View details →DOI: 10.1007/s10151-026-03350-4 Negative / Null Result Report
Murray CS, Marx L, Aluru N et al. · 2026 · Preprint
Ocean Alkalinity Enhancement (OAE) is a marine carbon dioxide removal (mCDR) strategy that involves adding alkaline substances to surface waters to enhance CO 2 uptake and storage. The dispersal of alkaline materials such as sodium…
View details →DOI: 10.64898/2026.02.03.700700 Negative / Null Result ReportMedicine
Ichie K, Asomugha A, Okafor I · 2026 · BMC neuroscience
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder strongly associated with dopaminergic neuronal degeneration and alpha-synuclein pathology. Paraquat (PQ) has been implicated in Parkinsonian neurodegeneration;…
View details →DOI: 10.1186/s12868-026-01019-0 Negative / Null Result ReportMedicine
Somerville E, Bollinger RM, Haxton M et al. · 2026 · OTJR : occupation, participation and health
Interventions to address polypharmacy and improve adherence are insufficient for community-dwelling older adults. To examine the feasibility, acceptability, and preliminary efficacy of a tailored medication management intervention (TIMM)…
View details →DOI: 10.1177/15394492261442163 Negative / Null Result ReportMedicine
Hsieh YC, Lu WY, Chen YL et al. · 2026 · BMC ophthalmology
Background Selective laser trabeculoplasty (SLT) is a widely accepted treatment for primary open-angle glaucoma (POAG), but its role in primary angle-closure glaucoma (PACG) remains less defined. This study aimed to evaluate the short-term…
View details →DOI: 10.1186/s12886-026-05058-3 