Negative / Null Result ReportMedicine
Hakkani Öznay Ç, Findik H, Uzun F et al. · 2026 · Journal of clinical medicine
Objectives : To prospectively compare the outcomes of external dacryocystorhinostomy (EX-DCR), endonasal dacryocystorhinostomy (EN-DCR), and laser-assisted transcanalicular dacryocystorhinostomy (TL-DCR) in patients with nasolacrimal duct…
View details →DOI: 10.3390/jcm15124488 Negative / Null Result Report
Sorjonen K, Melin B, Melin M · 2026 · Preprint
Ji et al. recently reported evidence suggesting that marital satisfaction serves as a longitudinal protective factor against postpartum depressive symptoms, basing this conclusion on statistically significant paths estimated with…
View details →DOI: 10.31234/osf.io/wrf3x_v1 Negative / Null Result ReportMedicine
Smith A, Dixit I, Zhang L et al. · 2026 · JAMA dermatology
Importance Cardiovascular disease (CVD) is the leading cause of mortality in patients with psoriasis, yet structured CVD prevention is not routinely embedded in dermatology care. Objective To evaluate the effectiveness of a text-messaging…
View details →DOI: 10.1001/jamadermatol.2026.1070 Negative / Null Result ReportOpen accessMedicine
Parkhoo K, Schmitz LA, Fröb L et al. · 2026 · Dentistry journal
Objectives : Six dentin adhesives were tested in vitro regarding their cytotoxicity toward human fibroblasts. AdheSE, Clearfil SE Bond, Hybrid Bond, One-up Bond F Plus, Optibond Solo Plus, and Syntac were tested using a cell culture model.…
View details →DOI: 10.3390/dj14050312 Negative / Null Result ReportOpen accessMedicine
Korodimos N, Wojtyś ME, Kostopanagiotou K et al. · 2026 · Journal of clinical medicine
Background: Non-small-cell lung cancer (NSCLC) is driven by distinct oncogenic alterations with important therapeutic and prognostic implications. Noninvasive biomarkers that predict molecular status in surgically resectable disease may…
View details →DOI: 10.3390/jcm15114100 Negative / Null Result ReportOpen accessMedicine
Mahajan A, Haideri S, Kumar VVH et al. · 2026 · Journal of education and health promotion
Background The oral health is an integral part of general well-being in children suffering from attention deficit hyperactivity disorder (ADHD). The present study aimed to analyze the impact of oral health education program on children…
View details →DOI: 10.4103/jehp.jehp_1102_25 Negative / Null Result ReportOpen accessMedicine
Abdi A, Abbasi E, Abazarlou A · 2026 · BMC neurology
Objectives Migraine is a common and disabling neurological disorder in children, often requiring preventive treatment. This study aimed to compare the efficacy and tolerability of cinnarizine and topiramate in the prophylaxis of migraine…
View details →DOI: 10.1186/s12883-026-04950-1 Negative / Null Result ReportMedicine
Peker N, Yücetürk A, Tığlı E et al. · 2026 · Journal of ovarian research
Background We aimed to evaluate whether delayed initiation of gonadotropin hormone-releasing hormone (GnRH) antagonist treatment affects premature ovulation and the number of good-quality blastocysts. We retrospectively reviewed the…
View details →DOI: 10.1186/s13048-026-02161-3 Negative / Null Result ReportOpen accessMedicine
Yan Z, Jiang Q, Lu Z et al. · 2026 · International journal of general medicine
Background Intervertebral disc degeneration (IVDD) is a major cause of low back pain. Observational studies suggest a link with gut microbiota (GM), possibly mediated by systemic inflammation, but causality remains unclear. Objective To…
View details →DOI: 10.2147/ijgm.s615488 Negative / Null Result ReportOpen accessMedicine
Ilbekova K, Ibrayeva D, Saifulina E et al. · 2026 · Journal of clinical medicine
Background/Objectives : Cancer incidence and mortality are key epidemiological indicators for evaluating the long-term biological effects of chronic low-dose radiation exposure. The aim of this study was to assess the incidence, structure,…
View details →DOI: 10.3390/jcm15114330 Negative / Null Result Report
Plaikner A, Ploner M, Sewald Z et al. · 2026 · Preprint
Protein Language Models (pLMs) have significantly advanced computational biology. Yet their scale and reliance on redundant training data raise a fundamental question: do pLMs generalize the statistical grammar of proteins, or do they…
View details →DOI: 10.64898/2026.06.08.730685 Negative / Null Result ReportMedicine
Shan J, Yu J, Zhao L et al. · 2026 · BMC cancer
Background Dose reduction during concurrent chemoradiotherapy (cCRT) is frequently required in patients with limited-stage small-cell lung cancer (LS-SCLC) because of treatment-related toxicities or poor tolerance. However, the impact of…
View details →DOI: 10.1186/s12885-026-16150-8 Negative / Null Result Report
Mohammed S, Kyei L, Okyere F et al. · 2026 · Preprint
Abstract Background: PAM50 molecular subtype is an established prognostic factor in breast cancer, yet unmeasured heterogeneity may persist within and between subtypes. We evaluated whether shared frailty modeling provides additional…
View details →DOI: 10.21203/rs.3.rs-9931861/v1 Negative / Null Result ReportOpen accessMedicine
Alkhalifah OF, Ali Shah S, Tareen SUK et al. · 2026 · Cureus
Background Achieving a lifelike color match for anterior restorations is a persistent challenge because tooth appearance is heavily influenced by illumination and observer-dependent choices. While visual matching with VITA-type guides…
View details →DOI: 10.7759/cureus.108421 Negative / Null Result Report
Kiplimo D, Sperber S, Nata’ala MK et al. · 2026 · Preprint
Abstract Background Antimicrobial resistance (AMR) in plant-associated microbiomes is increasingly recognized as One-Health concern. Apples are widely consumed, yet little is known about how agricultural practices and geography shape its…
View details →DOI: 10.21203/rs.3.rs-9344661/v1 Negative / Null Result ReportOpen accessMedicine
Matsumoto T, Yamamoto Y, Kotaka M et al. · 2024 · Targeted oncology
Background Non-inferiority of trifluridine/tipiracil (FTD/TPI) plus bevacizumab (BEV) to irinotecan/fluoropyrimidine plus BEV in metastatic colorectal cancer was investigated in the phase III TRUSTY study, and we conducted a phase II study…
View details →DOI: 10.1007/s11523-024-01043-2 Negative / Null Result ReportOpen access
Halpin M, Lerner A, Sagar M et al. · 2023 · Preprint
The systemic inflammatory response seen in patients with severe COVID-19 shares many similarities with the changes observed in hemophagocytic lymphohistiocytosis (HLH); a disease characterized by excessive immune activation. Many patients…
View details →DOI: 10.1101/2023.06.05.23290969 Negative / Null Result ReportMedicine
Webers C, Ortolan A, Sepriano A et al. · 2023 · Annals of the rheumatic diseases
Objective To update the evidence on efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in patients with axial spondyloarthritis (axSpA) to inform the 2022 update of the Assessment of SpondyloArthritis…
View details →DOI: 10.1136/ard-2022-223298 Negative / Null Result ReportOpen accessMedicine
Ma XT, Yao GY, Li JL et al. · 2025 · World journal of clinical oncology
Background Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) represents a distinct molecular cancer subtype that is often associated with a poor prognosis. While perioperative chemotherapy regimens are currently…
View details →DOI: 10.5306/wjco.v16.i11.112029 Negative / Null Result ReportOpen accessMedicine
Mujayridi M, Matinlinna J, Silikas N · 2026 · Materials (Basel, Switzerland)
Three-dimensional (3D) printing is increasingly used for the fabrication of definitive crowns; however, whether specific post-curing hardware is mandatory for clinical success remains a practical concern. This study provided a practical…
View details →DOI: 10.3390/ma19091886 Negative / Null Result ReportMedicine
Duc TA, Ha NTT, Toan NK et al. · 2026 · La Clinica terapeutica
Background Labor induction is commonly performed in high-risk pregnancies, but can also be beneficial in low-risk populations, as shown in the ARRIVE trial. This study aimed to compare the effectiveness and pregnancy outcomes of labor…
View details →DOI: 10.7417/ct.2026.2080 Negative / Null Result ReportMedicine
Ayesh W, Houry E, Hodges G · 2026 · The neurologist
Objective Optimal timing of initiation of pharmacologic venous thromboembolism (VTE) prophylaxis following intracerebral hemorrhage is controversial. This study aims to assess the association between the timing of pharmacologic VTE…
View details →DOI: 10.1097/nrl.0000000000000662 Negative / Null Result ReportOpen accessMedicine
Novikova L, Lang C, Tumani H et al. · 2026 · Brain communications
Weight loss, partially caused by hypermetabolism, represents a well-documented and therapeutically relevant feature of the amyotrophic lateral sclerosis phenotype worldwide. In this study, we retrospectively analysed the association…
View details →DOI: 10.1093/braincomms/fcag198 Negative / Null Result ReportOpen accessMedicine
Gür S, Soyal M · 2026 · BMC sports science, medicine & rehabilitation
BACKGROUND: Resistance training plays a crucial role in the planning and implementation of all sports requiring optimal performance. The literature on resistance exercise encompasses many different methods. The aim of this study is to…
View details →DOI: 10.1186/s13102-026-01687-9 Negative / Null Result ReportMedicine
Türk B, Metin G, Fencki SM et al. · 2026 · Journal of bodywork and movement therapies
Background Type 2 diabetes mellitus (T2DM) can impair musculoskeletal function, affecting the shoulder's mobility, proprioception, and functional stability. Despite its growing prevalence, shoulder involvement in T2DM remains largely…
View details →DOI: 10.1016/j.jbmt.2026.05.011 Negative / Null Result ReportMedicine
Yıldırım D, Zorluoğlu SL, Navruz ES et al. · 2026 · BMC oral health
Background Oral and dental health education is typically delivered using visual methods on jaw models. However, these methods are insufficient for individuals with visual impairments. This study aims to contribute to the oral and dental…
View details →DOI: 10.1186/s12903-026-08692-x Negative / Null Result ReportOpen accessMedicine
Sousa MM, Vieira LP, Pinho AR et al. · 2026 · JSES reviews, reports, and techniques
Background Radial head fractures are among the most common elbow injuries in adults. The choice between osteosynthesis and radial head arthroplasty (RHA) remains controversial, particularly in comminuted or unstable fracture patterns. This…
View details →DOI: 10.1016/j.xrrt.2026.100780 Negative / Null Result ReportOpen accessMedicine
Angenent A, Maaskant JM, Nieland L et al. · 2026 · European journal of pediatrics
This study evaluates the effect of a comfort assessment using focus language compared with pain assessment using the Numeric Rating Scale (NRS) on postoperative length of stay (LOS), analgesic use and patient and parental satisfaction.…
View details →DOI: 10.1007/s00431-026-06932-4 Negative / Null Result ReportOpen accessMedicine
Azmy Basiouny HM, Shafik AA, Elbarmelgi MY et al. · 2026 · BMC surgery
Background While current surgical approaches for obstructed defecation syndrome (ODS) primarily target rectocele and rectal intussusception, excessive perineal descent (PD) may contribute to persistent symptoms and suboptimal surgical…
View details →DOI: 10.1186/s12893-026-03888-y Negative / Null Result ReportOpen accessMedicine
Al-Eitan LN, Alasmar MK, Alorjani MS et al. · 2026 · Frontiers in medicine
Background Vitamin D exerts a protective role in carcinogenesis by regulating signaling pathways implicated in tumor growth and progression. Variants in CYP2R1, CYP24A1, CYP27B1, and DBP have been reported to influence circulating 25(OH)D…
View details →DOI: 10.3389/fmed.2026.1816935 