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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20289 results in Negative / Null Result Report · page 648 of 677

Negative / Null Result ReportMedicine

Olfactory function in patients with benign paroxysmal positional vertigo (BPPV): a cross-modal sensory analysis.

Tahsin S, Murat K, Gözde OK et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

OBJECTIVE: To investigate the potential interaction between the vestibular and olfactory systems by evaluating olfactory identification performance in patients with BPPV. METHODS: Fifty-two patients with BPPV and 50 age-matched healthy…

View details →DOI: 10.1007/s00405-026-10202-2
Negative / Null Result ReportMedicine

Postural Stability Changes During the 4 Phases of the Half Squat: Kinematics Profile of the Center of Pressure and Center of Mass in High-Performance Weightlifters-A Pilot Study.

Arrayales-Millán EM, Rodal M, González-Macías ME et al. · 2026 · Bioengineering (Basel, Switzerland)

This study investigated balance control during the half squat by analyzing the relationship between the center of mass (CoM) and the center of pressure (CoP) in five experienced male weightlifters performing segmented squats at five load…

View details →DOI: 10.3390/bioengineering13060711
Negative / Null Result ReportMedicine

Revisiting Marriage and Physical and Mental Health Among Partnered Gay and Lesbian Adults: An Analysis of Behavioral Risk Factor Surveillance System Data, 2014-2023.

Song H · 2026 · LGBT health

Purpose The purpose of this study was to reexamine the association between marriage and health among partnered gay and lesbian adults, comparing married individuals with those in unmarried couples. Methods Using a decade of large-scale,…

View details →DOI: 10.1177/23258292251385566
Negative / Null Result ReportMedicine

Lack of Lumpfish (Cyclopterus lumpus) Susceptibility to the Infectious Salmon Anaemia Virus (ISAV) Using In Vivo Challenges.

Gagné N, Ditlecadet D, Hébert K et al. · 2026 · Journal of fish diseases

Infectious salmon anaemia virus (ISAV) can cause disease and mortality in Atlantic salmon (Salmo salar). The virus is endemic in several regions including the Atlantic coast of Canada. Lumpfish (Cyclopterus lumpus) are increasingly…

View details →DOI: 10.1111/jfd.70141
Negative / Null Result ReportMedicine

(No) attentional biases in obsessive-compulsive disorder? An eye-tracking study using idiosyncratic stimulus material.

Müller CL, Ehring T, Kustermann A et al. · 2026 · Journal of psychopathology and clinical science

Cognitive-behavioral theories propose that attentional biases contribute to the development and maintenance of obsessive-compulsive disorder (OCD). However, research findings have been inconsistent, with some studies supporting vigilance…

View details →DOI: 10.1037/abn0001071
Negative / Null Result ReportMedicine

Pregnancy Hormones and Offspring Psychiatric Problems: Testing Associations Between Placental Corticotropin-Releasing Hormone and Children's Age 8 Internalizing Outcomes.

Sullivan ADW, Barrett ES, Sullivan A et al. · 2026 · Biopsychosocial science and medicine

Objective Placental corticotropin-releasing hormone (pCRH) is a peptide essential for fetal development and birth timing. Prenatal programming frameworks position maternal pCRH as a primary neuroendocrine mediator underlying the…

View details →DOI: 10.1097/psy.0000000000001478
Negative / Null Result ReportMedicine

Cross sectional analyses indicated that body fat distribution was not associated with performance-based and self-reported outcomes among ambulatory people with multiple sclerosis.

Kidwell-Chandler A, Jeng B, Motl RW · 2026 · Multiple sclerosis and related disorders

Background Obesity is cited as a relevant factor in multiple sclerosis (MS). To date, there is inconsistent evidence regarding the relationship between total body fat and frequently studied outcomes in MS. Body fat distribution, or the…

View details →DOI: 10.1016/j.msard.2026.107084
Negative / Null Result ReportMedicine

Nocturnal Hypoxemia and Incident Coronary Artery Disease in Obstructive Sleep Apnea: Results from the Sleep Apnea Patients in Skaraborg Study.

Peker Y, Hjälm HH, Glantz H et al. · 2026 · Balkan medical journal

Background The relationship between obstructive sleep apnea (OSA) and coronary artery disease (CAD) remains controversial. Although observational studies have suggested that OSA is associated with an increased risk of coronary events,…

View details →DOI: 10.4274/balkanmedj.galenos.2026.2026-3-213
Negative / Null Result ReportMedicine

Safety of drug-eluting stent in Chinese population with or without diabetes: a multi-center registry study.

Cao S, Ling M, Zhang X et al. · 2026 · BMC cardiovascular disorders

Background The safety of drug-eluting stents (DES) in patients undergoing percutaneous coronary intervention (PCI) remains largely lacking in China. This study aimed to determine the 1-year adverse outcomes in a large registry of patients…

View details →DOI: 10.1186/s12872-026-06060-9
Negative / Null Result Report

Association of Driver Oncogenic Alterations with SUVmax, Preoperative Serum Calcium, and Smoking Status in Surgically Resected Non-Small Cell Lung Cancer: A Retrospective Single-Center Study

Korodimos N, Wojtyś ME, Kostopanagiotou K et al. · 2026 · Preprint

Background: Non-small cell lung cancer (NSCLC) is driven by distinct oncogenic al-terations with important therapeutic and prognostic implications. Noninvasive bi-omarkers that predict molecular status in surgically resectable disease may…

View details →DOI: 10.20944/preprints202605.0394.v1
Negative / Null Result ReportOpen accessMedicine

Investigation of Contrast-Induced Neurotoxicity and the Effects of Sildenafil and <i>N</i>-Acetylcysteine on HIF-1α Levels in Wistar Rats.

Altintop I, Tatli M, Sarica ZS et al. · 2026 · Brain sciences

Background Contrast-induced encephalopathy (CIE) is an uncommon yet clinically significant complication associated with iodinated contrast media, with its mechanisms remaining unclear. Objective The aims of this study are to examine the…

View details →DOI: 10.3390/brainsci16040362
Negative / Null Result ReportMedicine

Comparison of esketamine combined with dexmedetomidine versus propofol combined with midazolam on drug-induced sleep endoscopy: a randomized controlled trial.

Jiang Y, Wang Z, Wen H et al. · 2026 · BMC anesthesiology

Background Drug-induced sleep endoscopy (DISE) is widely used to evaluate upper airway obstruction in patients with obstructive sleep apnea syndrome (OSAS). We aimed to compare the sedative efficacy and safety of esketamine combined with…

View details →DOI: 10.1186/s12871-026-03987-6
Negative / Null Result ReportMedicine

Prognostic Value of BUN-Based Ratios for Mortality and Prolonged Hospitalization in Acute Upper Gastrointestinal Bleeding: Comparison with Established Risk Scores.

İnan B, Erdoğan Ç, Keskin ET et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : This study investigated the prognostic value of two simple blood urea nitrogen (BUN)-based ratios, BUN/hemoglobin (Hb) and BUN/Albumin, for predicting in-hospital mortality and prolonged hospitalization in…

View details →DOI: 10.3390/medicina62061210
Negative / Null Result ReportMedicine

Direct Maxillary Sinus Tissue Analysis for <i>TAS2R38</i> Polymorphisms: Establishing a Tissue-Based Translational Framework in Odontogenic Rhinosinusitis.

Greța-Oanță AL, Roman A, Berindan-Neagoe I et al. · 2026 · Journal of clinical medicine

Background/Objectives: Bitter taste receptors (T2Rs), specifically T2R38, are present in the respiratory epithelium and react with bacterial quorum-sensing molecules to induce an innate immunity response. Although TAS2R38 polymorphisms…

View details →DOI: 10.3390/jcm15124836
Negative / Null Result ReportMedicine

Inhibitory Control and Creativity in Children With Mild Intellectual Disabilities.

Japundža-Milisavljević M, Buha N, Milanović-Dobrota B · 2026 · Journal of applied research in intellectual disabilities : JARID

Background The study is based on the Dual Pathway to Creativity Model and explores the relationship between inhibitory control and creativity in children with mild intellectual disabilities. Method The sample consisted of 58 children with…

View details →DOI: 10.1111/jar.70213
Negative / Null Result ReportMedicine

Factors Affecting the Quantitative Value of the Pivot Shift Test Using a Navigation System in Anterior Cruciate Ligament Injured Knees.

Nakamae A, Nekomoto A, Nakata K et al. · 2026 · The journal of knee surgery

Abstract This study aimed to identify factors associated with greater quantitative pivot shift in anterior cruciate ligament (ACL)-injured knees by quantitatively assessing the pivot shift under anesthesia using a navigation system prior…

View details →DOI: 10.1055/a-2865-3249
Negative / Null Result ReportMedicine

Evaluation of the Effect of Different Drilling Systems on Trabecular Bone Microarchitecture During Implant Cavity Preparation Using CBCT: Ex Vivo Study.

Cakir M, Buyuk C, Kan B · 2026 · The International journal of oral & maxillofacial implants

Purpose Achieving optimal primary stability is critical for dental implant success, particularly in low-density bone regions such as the posterior maxilla. Conventional high-speed drilling with irrigation may remove vital bone fragments…

View details →DOI: 10.11607/jomi.11740
Negative / Null Result ReportOpen accessMedicine

Dosimetric Impact of Artificial Intelligence (AI)-Based Autocontouring Software, OncoStudio, in High-Risk Prostate Cancer Treatment Planning: A Three-Group Comparative Study on the Slice Ranges of Seminal Vesicles.

Kawaguchi M, Hoshina M, Sugahara S et al. · 2026 · Cureus

Objective This pilot study investigated the dosimetric impact of artificial intelligence (AI)-generated seminal vesicle (SV) autocontouring (AC) compared with manual contouring (MC) in high-risk prostate cancer volumetric-modulated arc…

View details →DOI: 10.7759/cureus.103403
Negative / Null Result ReportMedicine

Real-World Outcomes of Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiotherapy in Stage II-III Locally Advanced Rectal Cancer: A Comparative Cohort Study.

Erken AA, Dincer ST · 2026 · Asia-Pacific journal of clinical oncology

Aim Total neoadjuvant therapy has been adopted to improve systemic disease control in locally advanced rectal cancer, yet long-term real-world outcomes, particularly in non-Western populations, remain incompletely defined. We compared…

View details →DOI: 10.1111/ajco.70118
Negative / Null Result ReportMedicine

Inflammatory Biomarkers and Their Associations with Arrhythmic Burden Following SGLT2-I Treatment in Chronic Heart Failure-A Subanalysis of the ERASe Trial.

Benedikt M, Herrmann M, Aziz F et al. · 2026 · Journal of clinical medicine

Background : Sodium glucose-linked transport 2 inhibitors (SGLT2-Is) are well known to exert beneficial effects in chronic heart failure (CHF) independent of left ventricular ejection fraction (LVEF). As inflammation plays a key role in…

View details →DOI: 10.3390/jcm15124681
Negative / Null Result ReportOpen accessMedicine

Two versus three cannulated screws in pediatric Delbet type II femoral neck fractures: a retrospective comparative study.

Erdoğan F, Cengiz T, Şimşek ŞA et al. · 2026 · Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES

Background Pediatric femoral neck fractures are rare but carry a high risk of complications such as avascular necrosis (AVN), premature physeal closure, and coxa vara. Although stable internal fixation is essential, the optimal number of…

View details →DOI: 10.14744/tjtes.2026.97273
Negative / Null Result ReportMedicine

Outcome of preterm newborns admitted with respiratory distress in relation to time of initiation of CPAP.

Pandey K, Choubey B, Gupta N et al. · 2026 · Journal of neonatal-perinatal medicine

BackgroundRespiratory distress is a frequent complication in preterm infants, often requiring respiratory support. Respiratory distress syndrome (RDS), caused by surfactant deficiency in the immature lung, is the predominant etiology in…

View details →DOI: 10.1177/19345798261443957
Negative / Null Result ReportMedicine

[Influenza virus infection affects the efficacy of the treatment of dyslipidemia in mice with a polyisoprenoid-based drug].

Makiev EA, Kozhevnikova TN, Pronin AV et al. · 2026 · Voprosy virusologii

Objective To evaluate how influenza infection affects the hypolipidemic effect of a novel combined drug - Prenophytol based on polyisoprenoids (sodium polyprenyl phosphate and beta-sitosterol) in mice with experimental dyslipidemia.…

View details →DOI: 10.36233/0507-4088-343