Negative / Null Result ReportOpen accessMedicine
Nilgün Solmaz, Onur Yaya, Feyza Önder · 2014 · Türk Oftalmoloji Dergisi
Objectives: Evaluation of structural alterations of the optic nerve head (ONH) and the retinal nerve fiber layer (RNFL) in patients with ocular hypertension (OHT) and early-stage glaucoma and assessment of the discriminatory diagnostic performance of spectral-domain optical coherence tomography (SD-OCT) Copernicus (Optopol Technology S.A.). Materials and Methods: This study included 59 eyes of a total of 59 patients, 29 of whom were diagnosed with OHT (Group 1) and 30 with early-stage glaucoma (Group 2). The differentiation of early-stage glaucoma and OHT was carried out on the basis of standa
View details →DOI: 10.4274/tjo.71677 Negative / Null Result ReportOpen accessScience (General)
Fenise Selin Karali, Samet Tosun, Meltem Şen-Aksüt et al. · 2024 · Heliyon
Cyberloafing is the use of (e.g. smartphones, tablets, laptops, and the Internet) for purposes other than work related reasons during work hours. Although cyberloafing in the workplace has been widely investigated, there is relatively a small number of studies on cyberloafing behaviors in educational settings, which refer to students' tendencies to use technology for non-class-related purposes during lectures. The goal of the current study is to determine how frequently and for what purposes speech and language therapy (SLT) students at Biruni University engage in cyberloafing during lectures.
View details →DOI: 10.1016/j.heliyon.2024.e31068 Negative / Null Result ReportOpen accessGynecology and obstetrics
Fariba Mousavi, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirgafourvand et al. · 2023 · Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Early symptoms of menopause are very common and often very bothersome. Considering the increasing number of women experiencing these symptoms in the world and Iran, there is a growing need to use methods to reduce these symptoms. Therefore, this study was performed with aim to determine the effect of the combined herbal capsules (Menohelp) on reducing the early symptoms of menopause, number and intensity of hot flashes (primary outcomes), and improving sleep quality and quality of life (secondary outcomes) in menopausal women. Methods: In this double-blind trial in Tabriz, 100 wo
View details →DOI: 10.22038/ijogi.2023.22601 Negative / Null Result ReportOpen accessDentistry
Ebrahim Amin Salehi, Haleh Heshmat, Elham Moravej Salehi et al. · 2013 · Journal of Islamic Dental Association of Iran
Background and Aim: Intraoral repair of fractured porcelain is an acceptable method to avoid replacement and therefore saving time and cost. The purpose of this study was to determine the in-vitro shear bond strengths of composite resin to feldspathic porcelain after different durations of sandblasting and to compare the effect of sandblasting with that of hydrofluoric acid (HF ). Materials and Methods : In this in-vitro study, 40 porcelain disks were fabricated and randomly divided into 4 groups (n=10). Porcelain surface in group 1 was etched with 9.5% HF for 2 minutes. Groups 2, 3 and 4 were
Negative / Null Result ReportOpen accessMedicine
Olvera-Maneu S, Regidor M, Serres-Corral P et al. · 2026 · Animals : an open access journal from MDPI
Fecal glucocorticoid metabolites (FGM) are widely used to assess hypothalamic-pituitary-adrenal (HPA) activity in vertebrates, but their applicability to reptiles, and more specifically to snakes, remains poorly explored. The objective of…
View details →DOI: 10.3390/ani16101485 Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
Irfan Zubair Shahul Hameed, Darpanarayan Hazra, Priya Ganesan et al. · 2024 · Turkish Journal of Emergency Medicine
OBJECTIVES: In the context of acute hypoxemic respiratory failure (AHRF), ensuring effective preoxygenation and apneic oxygenation emerges as the pivotal approach ensuring for averting hypoxemic adverse events during endotracheal intubation. To investigate this, we conducted an open-label randomized controlled trial, aiming to assess the comparative effectiveness of nasopharyngeal high-flow oxygenation in conjunction with Bag-Valve-Mask (BVM) versus standard BVM preoxygenation in patients experiencing AHRF within the emergency department (ED). METHODS: This prospective single-center, open-labe
View details →DOI: 10.4103/tjem.tjem_176_23 Negative / Null Result ReportOpen accessMedicine
Pola farhad hassan, Hamdia Mirkhan Ahmed · 2019 · Diyala Journal of Medicine
Background: Benefits of minimally invasive or laparoscopic procedures include less post operative discomfort. Objective: This study aimed to identify the early postoperative complications of laparscopic cholecystectomy and their association with age, occupation and previous laparatomy. Patients and Methods: 60 female patients diagnosed with having symptomatic gallstone underwent laparscopic cholecystectomy in Pirmam General Hospital, during the period from Jan 2015 to Jul 2015. Surgery done by researchers and after 10 days, the patient interviewed and examined for finding the complications, th
Negative / Null Result ReportOpen accessMedicine (General)
Seyed Hosein Tabatabaei, Seyed Mehdi Kalantar, Mohammad Hasan Akhavan Karbassi et al. · 2021 · Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Considering the importance of oral health as a part of general health and the role of physicians in community health, the present study was conducted to investigate the relationship between common oral diseases and general body health from the perspective of medical students in Yazd City in 2018. Methods: In this descriptive cross-sectional study, 210 internship and pre-internship students of Shahid Sadoughi University of Medical Sciences in Yazd Cityin 2018 were selected randomly and their knowledge about common oral and dental diseases and its relationship with general body hea
Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Fereshteh Baygi, Mostafa Qorbani, Mohammad Esmaeil Motlagh et al. · 2020 · BMC Cardiovascular Disorders
Abstract Background This study evaluated the association of frequency of potato and rice consumption with cardiometabolic risk factors in children and adolescents. Methods This nationwide cross-sectional survey was conducted on 14,400 children and adolescents. Fasting blood was obtained from a sub-sample of 4200 randomly selected students. Physical examination and laboratory tests were conducted under standard protocols. Metabolic Syndrome (Mets) was defined based on the Adult Treatment Panel III criteria modified for the pediatric age group. The self-reported frequency consumption of white ri
View details →DOI: 10.1186/s12872-020-01524-y Negative / Null Result ReportOpen accessMedicine
Xuetao Zhu, Yixiang Zhao, Kaiwen Liu et al. · 2024 · Scientific Reports
Abstract To compare the clinical efficacy of interlaminar endoscopic surgical system delta (iLESSYS-Delta) discectomy with that of classical fenestration discectomy for treating lumbar disc herniation. Patients who underwent iLESSYS-Delta or fenestration discectomy were enrolled in this study. Baseline information and clinical indicators were collected. The baseline data were matched using propensity score matching. Fifty-two patients were in each group. In the iLESSYS-Delta cohort, the volume of intraoperative bleeding was 18.17 ± 4.20 ml, the length of postoperative hospital stay was 4.16 ±
View details →DOI: 10.1038/s41598-024-70973-8 Negative / Null Result Report
Caldana M, Rusconi E · 2026 · Preprint
Olfaction is one of our most archaic senses but its central mechanisms are lesser known than those of other senses. In this work, we address a possible link between olfactory stimuli and mental spatial representations. Although olfactory…
View details →DOI: 10.31234/osf.io/nk3ty_v3 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Michael Christian Leitner, Michael Christian Leitner, Michael Christian Leitner et al. · 2023 · Frontiers in Neurology
IntroductionA significant number of Restitution Training (RT) paradigms claim to ameliorate visual field loss after stroke by re-activating neuronal connections in the residual visual cortex due to repeated bright light-stimulation at the border of the blind and intact fields. However, the effectiveness of RT has been considered controversial both in science and clinical practice for years. The main points of the controversy are (1) the reliability of perimetric results which may be affected by compensatory eye movements and (2) heterogeneous samples consisting of patients with visual field de
View details →DOI: 10.3389/fneur.2023.1114718 Negative / Null Result ReportOpen accessPharmaceutical industry
Gabriela Rister Figueiredo Irie, Marly Aparecida Spadotto Balarin, Mariangela Torreglosa Ruiz-Cintra et al. · 2016 · Revista de Ciências Farmacêuticas Básica e Aplicada
Endometriosis is a chronic gynecological disease that displays some features similar to malignancy, such as local invasion, aggressive spread to distant organs and angiogenesis. Polymorphisms of the ACE gene have been linked with some vascular disease. To determine the frequency of the ACE I/D polymorphism in Brazilian patients with endometriosis compared to controls. This case-control study included a total of 134 women (49 endometriosis patients and 85 controls) who had undergone a laparoscopy or laparotomy. Molecular analysis was performed by polymerase chain reaction (PCR). For the statist
Negative / Null Result ReportOpen accessMedicine
Meera Niranjan Khadilkar, Nitin Ankle, Sheetal Harakuni · 2017 · Bengal Journal of Otolaryngology and Head Neck Surgery
Introduction Controversy regarding treatment of tonsillitis based on throat culture report still persists. If surface culture is a determinant of bacteriology of the core, then rational therapy could be aimed at organisms cultured by surface swab. Materials and Methods A Cross-sectional study was conducted on 100 patients of chronic tonsillitis who underwent tonsillectomy. Tonsil surface and core swabs were studied for aerobic and anaerobic growth. Result Eighty seven percent patients had aerobic growth on tonsil surface and ninety percent in tonsil core. Staphylococcus aureus was the commones
Negative / Null Result ReportOpen accessMedicine
Jinmann Chon, Hee-Sang Kim, Jong Ha Lee et al. · 2018 · Annals of Rehabilitation Medicine
ObjectiveTo evaluate the association between balance function and asymmetry of knee extension strength in an elderly Korean population.MethodsThe strength of the knee extensors in each leg was measured in 306 community-dwelling elderly subjects (age, 76.70±4.85 years) and 25 young healthy subjects (age, 34.23±8.93 years). Based on the difference in strength of both legs, the elderly subjects were divided into symmetric (n=128) and asymmetric (n=178) strength groups using an asymmetry cutoff 20%. We determined the postural control ability of the subjects using InBody posturography, Berg Balance
View details →DOI: 10.5535/arm.2018.42.1.113 Negative / Null Result ReportOpen accessOtorhinolaryngology
Iqra Zakir, Ahmad Ahmad, Hamdan Pasha et al. · 2022 · Iranian Journal of Otorhinolaryngology
Introduction:Tympanoplasty is a common surgery for chronic otitis media and has conventionally been performed with a microscope for decades. The trend of endoscopic minimally invasive surgeries has been increasing worldwide for the last few decades. Few studies have discussed the outcomes of microscopic and endoscopic tympanoplasty. This study aims to compare results of tympanoplasty done with microscope vs endoscope in terms of graft take rate and improvement in conductive hearing loss.Materials and Methods:We did a retrospective review of 120 patients (54 male and 66 female) who underwent Ty
View details →DOI: 10.22038/ijorl.2022.61234.3104 Negative / Null Result ReportOpen accessBiotechnology
Katja Oberhofer, Patrick D. Wettenschwiler, Navrag Singh et al. · 2018 · Applied Bionics and Biomechanics
The introduction of hip belts to backpacks has caused a shift of loading from the spine to the hips with reported improvements in musculoskeletal comfort. Yet the effects of different hip belt tensions on gait biomechanics remain largely unknown. The goal of this study was to assess the influence of backpack weight and hip belt tension on gait biomechanics. Data from optical motion capture and ground reaction forces (GRF) during walking were acquired in nine healthy male subjects (age 28.0 ± 3.9 years). Six configurations of a commercial backpack were analyzed, that is, 15 kg, 20 kg, and 25 kg
View details →DOI: 10.1155/2018/4671956 Negative / Null Result Report
Fetene GD, Mengistu YA · 2026 · Preprint
Abstract This study investigates the effect of export diversification on growth. The study applied an extended Cobb-Douglas production function model using data sourced from the World Bank Indicator database, ranging from 1994 to 2024. The…
View details →DOI: 10.21203/rs.3.rs-8447625/v1 Negative / Null Result ReportOpen accessMedicine
Mehmet Mahir Fersahoğlu, Ahmet Çakmak, Hüseyin Çiyiltepe et al. · 2022 · İstanbul Tıp Fakültesi Dergisi
Objective: To evaluate the effects of using different doses of ursodeoxycholic acid (UDCA) for six months in prevention of gallstones after Laparoscopic Sleeve Gastrectomy (LSG) on the formation of gallstones in the 6th and 12th months. Materials and Methods: The data of patients who underwent LSG for morbid obesity were analyzed. Three groups of 20 people were formed. These were the control group, Group I who were treated with UCDA 500 mg/day for six months after LSG, and Group II who were treated with UCDA 1000 mg/day for 6 months after LSG. Demographic characteristics, co-morbid diseases, c
View details →DOI: 10.26650/iuitfd.948141 Negative / Null Result ReportOpen accessMedicine
Videnović Nebojša, Mladenović Jovan, Pavlović Aleksandar et al. · 2019 · Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. In this study, the effects of applied anesthetic techniques were investigated in a retrospective analysis of obese patients and those with normal body mass index undergoing in vitro fertilization, using bispectral index as an indicator of anesthetic depth. Methods. In total 116 patients with normal body mass index were allocated to group N. Another 116 patients with body mass index > 30 kg/m2 were allocated to group O. Anesthetic protocol comprised midazolam for premedication, diclofenac for pre-emptive analgesia, propofol for induction and maintenance, alfentanil for a
View details →DOI: 10.2298/sarh180227040v Negative / Null Result ReportOpen accessMedicine (General)
Erol ŞENTÜRK, Selahattin TUĞRUL, Yavuz Selim YILDIRIM et al. · 2018 · Bezmiâlem Science
Objective:Systemic absorption of steroids is reasonable because of the lipophilic nature of steroids and high vascularity of the middle ear mucosa. To date, however, of the clinical trials designed to investigate this subject, to the best of our knowledge, none has been based on objective methods. This study aims to demonstrate whether the intratympanic administration of dexamethasone has any systemic effects.Methods:Seventeen patients had a total of five sessions of intratympanic dexamethasone treatment scheduled for every other day. The mean fasting blood glucose, serum cortisol, serum adren
View details →DOI: 10.14235/bs.2018.1943 Negative / Null Result ReportOpen accessMedicine
Ryogo Minamimoto, Toshiyuki Saginoya, Chisato Kondo et al. · 2015 · PLoS ONE
The aim of this multi-center study was to assess the diagnostic capability of visual assessment in L-methyl-11C-methionine positron emission tomography (MET-PET) for differentiating a recurrent brain tumor from radiation-induced necrosis after radiotherapy, and to compare it to the accuracy of quantitative analysis.A total of 73 brain lesions (glioma: 31, brain metastasis: 42) in 70 patients who underwent MET-PET were included in this study. Visual analysis was performed by comparison of MET uptake in the brain lesion with MET uptake in one of four regions (around the lesion, contralateral fro
View details →DOI: 10.1371/journal.pone.0132515 Negative / Null Result ReportOpen accessMedicine
Mayuri Biccodu Shivashankar, Nandini Thippannanavar Niranjan, Arun Jayasheel et al. · 2016 · Journal of Clinical and Diagnostic Research
Introduction: Complete cleaning and shaping of root canal system is of paramount importance to achieve a successful root canal treatment. There are various rotary Ni-Ti systems available in the market to achieve mechanical goal of root canal preparation. But aggressive preparation of root canal with such systems would result in canal transportation and excess root dentin removal that would be one of the major reasons to decide the prognosis of root canal treated tooth. Aim: The present study was conducted to compare the root canal preparation in terms of canal transportation and volumetric cha
View details →DOI: 10.7860/jcdr/2016/20373.8788 Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Y. S. Kudryavtsev, M. M. Beregov, A. B. Berdalin et al. · 2021 · Вестник рентгенологии и радиологии
Objective: to compare the results of staging the severity of viral pneumonia in patients with COVID-19 based on the results of chest computed tomography (CT) using the empirical visual scale CT 0–4 and chest CT severity score (CT-SS) point scale, as well as to assess their prognostic value.Material and methods. Chest CT scans and anamnestic data in patients hospitalized to a non-specialized center repurposed for the treatment of new coronavirus infection, were analyzed. Chest CT analysis was performed by two radiologists using CT 0–4 and CT-SS scales.Results. The time course of changes in the
View details →DOI: 10.20862/0042-4676-2021-102-5-296-303 Negative / Null Result ReportMedicine
Wang Z, Yang J, Duan L · 2026 · Cognitive neurodynamics
Based on the important function of the thalamic reticular nucleus(TRN) in epileptic seizures, we explore how changes in TRN information affect epileptic seizures across the entire brain nervous system by adjusting the excitatory coupling…
View details →DOI: 10.1007/s11571-026-10482-8 Negative / Null Result ReportOpen accessMedicine
Mahdiyeh Harati-Sadegh, Leila Kohan, Batool Teimoori et al. · 2019 · Journal of Biomedical Science
Abstract Background Preeclampsia (PE), as a multisystem disorder, is associated with maternal hypertension and proteinuria. Apoptosis seems to be involved in the pathophysiology of PE, although its precise pathogenic mechanisms are not well established. In this study, we aimed to identify the association between maternal TP53-rs1042522, P21-rs1801270, and P21-rs1059234 polymorphisms and PE. In addition, we examined the effects of promoter methylation and TP53 and P21 polymorphisms on placental mRNA expression in PE women. Methods The blood of 226 PE women and 228 normotensive pregnant women wa
View details →DOI: 10.1186/s12929-019-0586-x Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Bharath Pandu, KHANNA D, Mohandass P et al. · 2022 · Iranian Journal of Medical Physics
Introduction: The study aims to compare target coverage and critical structure dose difference between various dose computing algorithms with small segment dose calculation in Intensity Modulated Radiation Therapy (IMRT) and large segment dose calculation in 3-Dimensional Conformal Radiation Therapy (3DCRT) treatment plan for Head and Neck (H&N) tumor.Material and Methods: For the present study, thirty-eight H&N cancer patients were selected retrospectively. Twenty-seven patients were planned with IMRT plan using Monte Carlo (MC) algorithm and eleven patients with 3DCRT plan using Collapsed Co
View details →DOI: 10.22038/ijmp.2022.63548.2082 Negative / Null Result ReportOpen accessDermatology
Fadime Mutlu İçduygu, Isil Deniz Oguz, Egemen Akgun et al. · 2026 · Dermatology Practical & Conceptual
Introduction: Psoriasis, a widespread inflammatory cutaneous disease, is driven by an interplay of genetic and environmental risk factors. miR-155 and miR-146a have been implicated in the regulation of inflammatory pathways. Objectives: In the current study, we examined the association between miR-155 rs767649 and miR-146a rs2910164 variants and the predisposition to psoriasis and psoriatic arthritis. Methods: A total of 544 individuals, including 284 psoriasis cases (68 with psoriatic arthritis) and 260 controls, were enrolled in the present study. Real-time polymerase chain reaction (qPCR) m
View details →DOI: 10.5826/dpc.1601a5977 Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Feng-Hang Chang, Alan M. Jette, Mary D. Slavin et al. · 2018 · BMC Musculoskeletal Disorders
Abstract Background The intent of this study was to examine and compare the ability to detect change of two patient reported outcome (PRO) instruments that use a computerized adaptive test (CAT) approach to measurement. The Patient Reported Outcomes Measurement Information System (PROMIS®) Physical Function scale is a generic PRO, while the Osteoarthritis Computerized Adaptive Test (OA-CAT) is an osteoarthritis-specific PRO. Methods This descriptive, longitudinal study was conducted in a community setting, involving individuals from the greater Boston area. Inclusion criteria: age > 50, self-r
View details →DOI: 10.1186/s12891-018-1942-9 Negative / Null Result ReportOpen accessMining engineering. Metallurgy
Yutaka ITO, Masato TAKEUCHI, Shuto MIKAMI et al. · 2020 · Journal of MMIJ
Productivity, safety and its improvement is also an integral part of a good mining operation. In recent times, due to constraints on time and cost, it has become increasingly harder to conduct training and safety inductions at mine sites. For the purpose of overcoming these limitations, the use of virtual reality (VR) is proposed for mining education and training. VR has already been introduced in the education and training of miners overseas, and quantitative studies on the effects of using VR for miner's education and training have been made. However, Japan has only one such application
View details →DOI: 10.2473/journalofmmij.136.33 