A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19906 results in Negative / Null Result Report · page 630 of 664
Hamadani, Banu, Wieczorek et al. · 2026 · Scientific reports
A soft-anchored titanium (Ti-6Al-4V) mesh implantable device was designed and morphologically characterised in an in vitro study. The mesh implant consists of a titanium mesh aimed at preserving continence and improving the quality of life…
Afifi, Hewaidy, El Shazly et al. · 2026 · Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
Chronic Achilles tendon rupture often requires surgical reconstruction. Flexor hallucis longus (FHL) tendon transfer is widely used, and endoscopic techniques may reduce soft-tissue morbidity and facilitate early recovery. Thirty patients…
Brochet, Cresseaux, Varazzani et al. · 2026 · Journal of stomatology, oral and maxillofacial surgery
Maxillo-zygomatic hypoplasia is common in patients with a Class III malocclusion, resulting in a flat and concave appearance of the midface. Le Fort I osteotomy is considered to be an effective treatment for occlusal and facial aesthetic…
Zhang, Hu, Huang et al. · 2026 · Molecular metabolism
Diabetic osteoporosis is characterized by disrupted bone remodeling involving impaired osteogenesis and excessive osteoclastic activity. Although glucagon-like peptide-1 receptor agonists (GLP-1RAs) have hypoglycemic benefits, their…
Ateş, Avşar · 2026 · Computers, informatics, nursing : CIN
Generation Z has grown up in the digital age, leading to different learning styles compared to previous generations. Therefore, traditional methods may not be sufficient to capture their attention. This study aimed to examine the effect of…
Istrate, Van Gelder, Szőllősi et al. · 2026 · Intensive care medicine
Environmental sustainability has become a critical concern across various sectors, including education and healthcare. Professional training programmes, particularly in intensive care medicine, are essential for maintaining competency but…
Tasdemir, Korkmaz, Durak et al. · 2026 · Turkish neurosurgery
To investigate lumbar motion and muscle change following hybrid surgery in adolescent idiopathic scoliosis (AIS). We conducted a prospective study design including 16 patients (14 female, 2 male) who underwent either hybrid surgery or…
Park, Lee, Koo et al. · 2026 · Clinics in orthopedic surgery
It is well known that the posteromedial (PM) buttress plays an important biomechanical role in ensuring stability in unstable intertrochanteric (INT) fractures. However, the necessity for the fixation of PM fragments remains controversial.…
Yi, Yoon, Lee et al. · 2026 · Cancer research and treatment
While triplet regimens are considered optimal for treatment of multiple myeloma (MM), the benefit of adding bortezomib to lenalidomide and dexamethasone remains prospective-wise unclear in elderly patients due to frailty and potential…
Sucu, Dereli, Aksan et al. · 2026 · BMC pregnancy and childbirth
The aim was to investigate the association between salt consumption and preeclampsia, as well as the effects of salt consumption on proteinuria, fetal-maternal Doppler parameters, and neonatal outcomes. This case-control study was…
Lasmanovich, Chepeliuk, Fihman et al. · 2026 · World journal of surgical oncology
Segmental ureterectomy (SU) is an established kidney-sparing strategy for upper tract urothelial carcinoma (UTUC), yet few studies have compared the standard open approach to the emerging robotic modality. We performed a clinical outcome…
Berthelot, Audureau, Bouleti et al. · 2026 · Archives of cardiovascular diseases
The MonCœur smartphone application (app) was developed to meet the specific needs of individuals living with heart failure (HF). To evaluate whether the MonCœur smartphone app improves self-care at 6months in patients with HF,…
Tissink, Timmerman, Vermeer et al. · 2026 · PloS one
Recurrent weight gain remains a challenge in metabolic bariatric surgery (MBS). Recent publications focused on ring-augmented Roux-en-Y gastric bypass (RYGB) and ring-augmented sleeve gastrectomy (SG), but few studies have addressed the…
Tsai, Li, Hsu et al. · 2026 · PloS one
Prostatic abscess, which is an uncommon urinary tract disease, can lead to mortality if not properly treated. This retrospective study aimed to identify risk factors associated with mortality in patients with prostatic abscess, with the…
Shamsoddini, Cheraghifard · 2026 · European geriatric medicine
Balance issues and the fear of falling are among the primary factors contributing to falls in older people, leading to injury and a decline in quality of life. A single-blind, randomized, controlled trial was conducted involving 34 older…
Kaman, Stork, Okumus et al. · 2026 · Langenbeck's archives of surgery
Segmentectomy is offered in selected patients with clinical T1a-b N0 M0 lung cancer. In case of positive N1 lymph node at fresh frozen section, conversion to lobectomy is recommended. Indication for redo surgery and completion lobectomy in…
Wang, Xiao, Li et al. · 2026 · Frontiers in pharmacology
Inferior ST-segment elevation myocardial infarction (STEMI) complicated by right ventricular involvement (RVMI) leads to right-heart-dominant failure and a higher incidence of cardiogenic shock (CS). Evidence guiding the choice between…
Larréché, Sodjinou, Tourita et al. · 2026 · Medecine tropicale et sante internationale
Hemorrhagic syndrome accounts for a significant proportion of the mortality and morbidity associated with snakebites in sub-Saharan Africa. Hyperfibrinolysis, which has been reported in some cases, suggests the potential benefit of…
Papale, Festino, Di Rocco et al. · 2026 · Biology of sport
Although there is a trend toward outdoor activities, limited research has examined the effects of outdoor exercise on blood pressure. This study aimed to compare the Systolic (sBP) and Diastolic (dBP) Blood Pressure, Heart Rate (HR)…
Yang, Dong, Song et al. · 2026 · Current medical imaging
The thymic veins are small vessels located in the anterior superior mediastinum, and thymic tissue undergoes physiological degeneration with age. Multidetector computed tomography (MDCT) with isotropic resolution allows comprehensive…
Larkin, Schiavon, Hajihassani · 2026 · Plant disease
In South Florida, the development and maintenance of high-quality golf courses are important to the state's economy. The courses, however, are commonly affected by plant-parasitic nematodes (PPNs), which are highly damaging. Effective…
Elenjickal, Baroz, Boileau et al. · 2026 · Diabetes, obesity & metabolism
Pharmacokinetic data suggest a potential dose-dependent effect of sodium-glucose co-transporter-2 (SGLT-2) inhibitors on surrogate markers of efficacy, but the impact of SGLT-2 inhibitor dose on renal and cardiovascular outcomes remains…
Wilcox, Campbell, Gill et al. · 2026 · The bone & joint journal
Computer navigation is capable of improving the accuracy of glenoid baseplate and screw positioning in shoulder arthroplasty, but there is very limited evidence of its effect on clinical outcomes. In Australia, there is one commonly used…
Metter, Dumoulin, Hay et al. · 2026 · Scandinavian journal of gastroenterology
Endoscopic submucosal resection (ESR) is a novel resection technique. ESR is performed with a partially insulated snare, which allows a resection close to the proper muscle layer thus resecting in the deep submucosa. This should have…
García Alcaide, Conde Villar, Pérez Alfayate et al. · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe
To assess the impact of a tailored ergonomic lecture on postural risk among second-year endodontic residents depending on the use of no magnification, ergonomic loupes, or an operating microscope. A within-subjects, repeated measures…
Qiao, Wang, Liu et al. · 2026 · BMC surgery
To evaluate the impact of sodium carboxymethyl cellulose (SCMC)-based absorbable hemostatic gauze on postoperative infectious outcomes in emergency laparoscopic appendectomy (LA) for acute appendicitis. A retrospective analysis of 184…
Herzog, Brink, Gondalia et al. · 2026 · Sports medicine (Auckland, N.Z.)
One often-stated aim of load management in elite athletes is injury reduction. However, current literature on the efficacy and effectiveness of specific load management strategies to reduce injury risk is limited. The aim of this study was…
Wang, Liu, Wang et al. · 2026 · Journal of neuro-oncology
H3K27M-mutant diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brainstem tumor with a median overall survival (OS) of less than one year. Radiotherapy (RT) is the standard treatment, but the survival benefit of adding…
Prasert, Praphasiri, Ditsungnoen et al. · 2026 · The Journal of infectious diseases
Antigenically drifted influenza A(H3N2) subclade K viruses have contributed substantially to influenza burden since 2025, but their clinical severity is less well described. Using sentinel surveillance data from Thailand, we found no…
Keskin, Erdoğan, Küçükçetin et al. · 2026 · Psychiatry research
The aim of this study was to compare serum levels of Fibroblast Growth Factor-2 (FGF-2) and Fibroblast Growth Factor-9 (FGF-9) between patients with Bipolar Disorder (BD) and healthy controls (HC), and to evaluate whether these molecules…