Negative / Null Result ReportMedicine
Abdelgaied MY, Abdelgawad O, Rashad MH et al. · 2026 · Journal of neuroimmunology
Background Neurodegeneration and inflammation can accelerate the demyelination process in multiple sclerosis (MS). We aimed to investigate the efficacy and tolerability of metformin as an add-on treatment to interferon Beta 1a (IFNβ-1a) in…
View details →DOI: 10.1016/j.jneuroim.2025.578852 Negative / Null Result ReportOpen accessMedicine
Aust H, Kranke P, Torossian A et al. · 2026 · Cancers
Background Isolated Perfusion Chemotherapy (IPC) with balloon occlusion creates transient ischemic tissue compartments while patients remain exposed to significant perioperative heat loss. Active warming during these phases is commonly…
View details →DOI: 10.3390/cancers18101640 Negative / Null Result ReportMedicine
Liu J, Nassrallah W, Quan-Nguyen C et al. · 2026 · Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
Objective The progression of glaucoma despite adequate intraocular pressure (IOP) control highlights the need for neuroprotective and neuroregenerative therapies. Preclinical studies suggest insulin promotes retinal ganglion cell survival…
View details →DOI: 10.1016/j.jcjo.2026.04.004 Negative / Null Result ReportMedicine
Brown JAR, Brewis HT, Kobor MS · 2026 · DNA repair
A range of genome maintenance factors respond to endogenous and exogenous DNA damage to prevent mutations and cell death. The scaffold protein, Rtt107, is important for the growth of cells exposed to DNA-damaging agents in the budding…
View details →DOI: 10.1016/j.dnarep.2026.103937 Negative / Null Result Report
Lindell D, Carlson MCG, Weissenbach J et al. · 2026 · Preprint
Viruses and grazers are fundamental agents of mortality in the oceans, impacting phytoplankton populations and organic matter cycling. Although viruses and grazers co-occur in nature, they are typically studied in isolation in laboratory…
View details →DOI: 10.64898/2026.06.10.731369 Negative / Null Result ReportMedicine
van der Meulen LWJ, Bergmans ME, Assil S et al. · 2026 · British journal of clinical pharmacology
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this…
View details →DOI: 10.1002/bcp.70630 Negative / Null Result ReportMedicine
Chakraborty S, Chatterjee S, S P et al. · 2026 · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Introduction The HYPORT Adjuvant trial is comparing a one-week (26 Gy) course of adjuvant breast radiotherapy (RT) to a three-week (40 Gy) course. We report the interaction of regional nodal irradiation (RNI) and the dose fractionation…
View details →DOI: 10.1016/j.radonc.2026.111576 Negative / Null Result ReportMedicine
Sumner C, Patel P, Spencer A et al. · 2026 · Journal of pediatric urology
Introduction Circumcision is a common surgical intervention, and pain is the most common complaint. Poorly managed pain can increase morbidity and reduce patient and parent satisfaction. Ketorolac, a non-steroidal anti-inflammatory drug…
View details →DOI: 10.1016/j.jpurol.2026.106034 Negative / Null Result ReportMedicine
Lim W · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy
Background and purpose Joint position sense (JPS) is frequently assessed using joint position reproduction (JPR); however, JPR has limitations, where reference angles are typically unavailable. This study aimed to examine the accuracy of…
View details →DOI: 10.1002/pri.70198 Negative / Null Result ReportMedicine
Lachowski K, Naja KM, Prill R et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Purpose Robotic-assisted (RA) surgery allows for higher accuracy in total knee arthroplasty (TKA) and for better standardization of alignment concepts. It was hypothesized that the more personalized component placement in functional…
View details →DOI: 10.1002/ksa.70380 Negative / Null Result ReportMedicine
Murray AL, Dryburgh K, Sonuga-Barke EJS · 2026 · Journal of attention disorders
Objective ADHD and internalising symptoms such as anxiety and depression are known to be associated in adolescence and understanding the mechanisms linking them is important for improving mental health outcomes for adolescents with ADHD…
View details →DOI: 10.1177/10870547261419589 Negative / Null Result ReportMedicine
Yoo S, von Keyserlingk MAG, Weary DM · 2026 · Journal of dairy science
Hot-iron disbudding is the most commonly used method for horn bud removal in dairy calves. Although factors such as post-treatment care, calf age, and the type of hot iron used have been studied in relation to wound healing, procedural…
View details →DOI: 10.3168/jds.2025-27866 Negative / Null Result ReportMedicine
Van Epps VM, Daur-Schierholz M, Dortenzio M et al. · 2026 · International journal of speech-language pathology
Purpose This pragmatic clinical trial examined the functional impact of a modified speech-language pathology intervention delivery model (including telepractice, reduced therapy frequency, and emphasised home programmes with parent…
View details →DOI: 10.1080/17549507.2026.2630835 Negative / Null Result ReportMedicine
Dockery R, Zevallos M, McNulty C et al. · 2026 · Developmental biology
All eukaryotes possess the essential mRNA cap-binding protein eIF4E, which initiates translation. This protein is highly conserved, with versions from zebrafish and humans able to rescue yeast. All fish also have an ancestral eIF4E family,…
View details →DOI: 10.1016/j.ydbio.2026.02.014 Negative / Null Result ReportOpen accessMedicine
Jiwane M, Karunanithy P, Goonawardhana D et al. · 2026 · Journal of surgical case reports
IgG4-related disease (IgG4-RD) is a multi-system disorder that rarely presents with gastric manifestations. A 26 year old woman presented with post-prandial symptoms of dyspepsia, dysphagia and reflux with a proximal submucosal gastric…
View details →DOI: 10.1093/jscr/rjag465 Negative / Null Result ReportMedicine
Htoo PT, Patorno E, Schneeweiss S et al. · 2026 · Clinical pharmacology and therapeutics
Benchmarking evidence from nonrandomized healthcare database studies against randomized clinical trials could strengthen confidence that database studies can reproduce known trial results and extend analyses to questions not directly…
View details →DOI: 10.1002/cpt.70241 Negative / Null Result Report
Yaghini O, Eslamian R, Abadi RNS et al. · 2026 · Preprint
Abstract Objective This study investigates the neurodevelopmental outcomes of infants with non-syndromic trigonocephaly managed surgically and conservatively. The aim is to assess whether earlier surgical intervention influences cognitive,…
View details →DOI: 10.21203/rs.3.rs-8631558/v1 Negative / Null Result ReportMedicine
Martins BB, Arrais AM, Pinto PHN et al. · 2026 · Animal reproduction science
The aim of this study was to compare recombinant bovine FSH (rbFSH) with a conventional multiple-dose purified porcine FSH (pFSH) for in vivo embryo production in sheep. Forty multiparous Santa Inês ewes were randomly assigned to two…
View details →DOI: 10.1016/j.anireprosci.2026.108232 Negative / Null Result Report
Rupietta AE, Meyer T, Margraf J et al. · 2026 · Preprint
Background: Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…
View details →DOI: 10.31234/osf.io/tcsre_v4 Negative / Null Result ReportMedicine
Outouil M, Daugherity EK, Warnick LD et al. · 2026 · Journal of the American Association for Laboratory Animal Science : JAALAS
Single-stall housing is a common system used for horses in various settings, including racing stables, riding schools, teaching and research facilities. Adequate stall space is necessary for horses to lie down and make postural…
View details →DOI: 10.30802/aalas-jaalas-25-152 Negative / Null Result Report
Zwyssig M, Schneider J, Selten G et al. · 2026 · Preprint
The plant-beneficial bacterium Pseudomonas protegens CHA0 (CHA0) is widely studied for the biological control of soil-borne plant diseases. Beyond its root-colonising capabilities, CHA0 can also infect and kill insect larvae and thus…
View details →DOI: 10.64898/2026.03.19.712869 Negative / Null Result ReportMedicine
Ündar A, Lussier MJ, Rajesh S et al. · 2026 · World journal for pediatric & congenital heart surgery
BackgroundDrawing on more than 30 years of valuable expertise in in-vitro, in-vivo, and clinical trials, we report the key findings of our institutional research on pulsatile cardiopulmonary bypass (CPB).MethodsA detailed search was…
View details →DOI: 10.1177/21501351251412887 Negative / Null Result ReportMedicine
Kieri O, Jütte BB, Vesterbacka J et al. · 2026 · HIV medicine
Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV-1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we…
View details →DOI: 10.1111/hiv.70235 Negative / Null Result ReportOpen accessMedicine
Glass-Biran AH, Eyre A, Stein G et al. · 2026 · BMJ open quality
Objective To evaluate whether adding a fourth physician to the emergency department night shift would improve metrics. Methods This retrospective cohort study used data from the Meir Medical Centre emergency department, 1 January 2021 to…
View details →DOI: 10.1136/bmjoq-2025-003648 Negative / Null Result ReportMedicine
Eliasson TM, Lundh Å, Höjer A et al. · 2026 · International Dairy Journal.
The objectives were to evaluate effects of feeding different types of silages on the microbiota of the raw milk and the resulting cheeses. Different silages were produced without additives, acid treated and inoculated with a LAB starter…
Negative / Null Result ReportMedicine
Caso JM, Fernández-Ruiz M, González E et al. · 2026 · Transplantation
Background Observational studies have shown that kidney transplant (KT) recipients who are cytomegalovirus (CMV)-seropositive (R+) but lack effective CMV-specific cell-mediated immunity (CMV-CMI) are at increased risk of CMV infection.…
View details →DOI: 10.1097/tp.0000000000005694 Negative / Null Result ReportMedicine
Strand DD, Ruf S, Sandoval-Ibáñez O et al. · 2026 · Plant physiology
The physiological role of the plastidial photosynthetic complex I (formerly NAD(P)H dehydrogenase-like complex, NDH) within the electron transport chain of plants remains intriguing. While the NDH complex shares homology with complex I, a…
View details →DOI: 10.1093/plphys/kiag010 Negative / Null Result ReportMedicine
Majeed A, Majeed S, Pandey A et al. · 2026 · Phytotherapy research : PTR
Withania somnifera , commonly known as Ashwagandha, is a widely recognized medicinal plant in India, belonging to the family Solanaceae, used in Ayurveda due to its diverse therapeutic properties. The roots of Ashwagandha are considered…
View details →DOI: 10.1002/ptr.70156 Negative / Null Result Report
Koh A · 2025 · Preprint
Duplication and segregation of genetic material are vital for cell proliferation. Deletion of DNA replication regulators, such as YabA and ParA, leads to over initiation of DNA replication. However, the viability of the ΔyabA ΔparA double…
View details →DOI: 10.1099/acmi.0.001000.v3 Negative / Null Result ReportOpen accessMedicine
Ali R, Yazdi A, Collins K et al. · 2026 · International journal of critical illness and injury science
Background Thiamine is a vitamin that plays a role in lactate clearance. Patients with sepsis may present with elevated lactate, and also in cirrhosis, as lactate is hepatically metabolized. Prior studies showed mixed results regarding the…
View details →DOI: 10.4103/ijciis.ijciis_124_25 