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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19906 results in Negative / Null Result Report · page 611 of 664

Negative / Null Result Report

Understanding Burnout in University Students With Physical Impairments: The Protective Roles of Social Support and Self- Concept

Onyedire NG, Ikenegbu T, Edward PU et al. · 2026 · Preprint

Abstract Background University students with physical impairments often face burnout in mainstream settings due to stigma, social barriers, and inadequate support. While social anxiety may heighten risk, self-concept and social support…

View details →DOI: 10.21203/rs.3.rs-8881107/v1
Negative / Null Result Report

Class Composition Effects in Achievement and Interest and the Role of the Learning Environment Revisited: A Conceptual Replication and Extension of Lavrijsen et al. (2022)

Kopatz M, Wagner W, Neuendorf C et al. · 2026 · Preprint

Class composition is a key contextual factor in students’ academic development. Prior research has mainly focused on class mean achievement, yet less is known about other composition characteristics, possible differences for students with…

View details →DOI: 10.31234/osf.io/zkg9r_v1
Negative / Null Result ReportMedicine

Ethnic-racial socialization and sociopolitical development among emerging adult college students of color.

Berkley S, Hoyt LT, Zeiders KH et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence

This study used multilevel growth modeling to examine associations between ethnic-racial socialization (ERS) and sociopolitical development among undergraduates of color (N = 125) attending predominantly White institutions during the 2016…

View details →DOI: 10.1111/jora.70156
Negative / Null Result ReportMedicine

Performance validity tests in a large racially and linguistically diverse pediatric and young adult clinical sample: Investigations of the TOMM, MVP, and MSVT.

MacAllister WS, Désiré N, Brooks BL · 2026 · The Clinical neuropsychologist

Objective There is strong support for the use of performance validity tests (PVTs) in all neuropsychological evaluations, however, research examining racial, ethnic, and linguistic differences in failure rates remains scarce, particularly…

View details →DOI: 10.1080/13854046.2026.2648272
Negative / Null Result Report

Temperature-sensitive cytoplasmic incompatibility across divergent Wolbachia partly reflects cifB transcription, not endosymbiont density

Bagchi B, Van Vlaenderen L, Wheeler T et al. · 2026 · Preprint

Maternally transmitted Wolbachia bacteria are common in insects, with many strains altering host reproduction through cytoplasmic incompatibility (CI). CI kills embryos fertilized by Wolbachia -bearing males unless those embryos also carry…

View details →DOI: 10.64898/2026.03.31.715596
Negative / Null Result ReportMedicine

Lymphatic Vessel Density or Area Are Not Reliable Prognostic Factors in Oral Cancer.

Cronblad IA, Warvik CE, Bjerkli IH et al. · 2026 · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology

Background Oral tongue squamous cell carcinomas (OTSCC) frequently metastasise via lymphatic vessels, thus lymphangiogenesis may enhance tumour cell dissemination by increasing tumour-lymphatic interactions. The prognostic significance of…

View details →DOI: 10.1111/jop.70148
Negative / Null Result ReportMedicine

Developmental regulation in adolescents with epilepsy who attend regular school: A comparative study part II.

Pfeiffer JP, Pinquart M, Neubauer BA · 2026 · Epilepsy & behavior : E&B

Objective Using strategies for achieving age-specific goals is essential for developmental regulation. In a previous study, we demonstrated that adolescents with epilepsy have difficulty achieving some of their goals, which necessitates…

View details →DOI: 10.1016/j.yebeh.2026.110971
Negative / Null Result ReportOpen accessMedicine

Insights into the influence of dog and guardian demographics, nutrition, and relationship on raw feeding practices.

Balousis P, Abood SK, Brazeau L et al. · 2026 · Frontiers in veterinary science

Introduction Raw meat-based diets (RMBD) are increasingly popular among dog guardians, yet the role of personal nutrition habits and pet-guardian relationships in their adoption remains unclear. This study examines how these factors,…

View details →DOI: 10.3389/fvets.2026.1793754
Negative / Null Result Report

Effect of Intravenous Lipid Emulsion Therapy on Xenobiotic Plasma Partitioning and Short-Term Neurological Outcome in Companion Animals with Suspected Neurotoxicosis: A Case Series

Voorhorst A, Pouzot-Nevoret C, Vernooij JC et al. · 2026 · Preprint

Intravenous lipid therapy (ILE) is used to treat neurotoxicosis in companion animals, but clinical evidence for in vivo xenobiotic partitioning and benefit remains limited. This study evaluated associations between the log n-octanol/water…

View details →DOI: 10.20944/preprints202602.1330.v1
Negative / Null Result ReportMedicine

The HBA-3 score: a simple bedside tool to predict cage subsidence after TLIF.

Najjar E, Khan S, Quraishi NA et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Background Cage subsidence is a common radiographic finding following transforaminal lumbar interbody fusion (TLIF), but its clinical relevance remains uncertain. Hounsfield Unit (HU) values from preoperative CT scans have emerged as…

View details →DOI: 10.1007/s00586-026-09906-0
Negative / Null Result ReportMedicine

Impact of patient-reported taxane-induced peripheral neuropathy on dose reductions or worsening quality of life in Black women with breast cancer: Analysis from ECOG-ACRIN EAZ171.

Ballinger TJ, Zhao F, Jiang G et al. · 2026 · Cancer

Background Black patients with breast cancer experience higher rates of taxane-induced peripheral neuropathy (TIPN), which may compromise chemotherapy dose delivery and health-related quality of life (HRQOL). Using the prospective…

View details →DOI: 10.1002/cncr.70466
Negative / Null Result ReportMedicine

Impact of adherence to six-month home-based HIIT on cardiorespiratory fitness in older adults.

Fosstveit SH, Feron J, Lohne-Seiler H et al. · 2026 · BMC sports science, medicine & rehabilitation

Background High-intensity interval training (HIIT) was originally designed to improve athletic performance, but a growing body of research over the past decade has highlighted its positive impact on various other health outcomes. However,…

View details →DOI: 10.1186/s13102-026-01750-5
Negative / Null Result ReportMedicine

The Association Between Social Determinants of Health, Race, and Sex on Risk for Readmission After Heart Transplantation.

Lemos C, Vargas F, Donald EM et al. · 2026 · Journal of cardiac failure

Background Women, racial and ethnic minority groups, and patients of low socioeconomic status (SES) face barriers linked to adverse outcomes after heart transplantation (HT). Data are lacking regarding the association of these demographics…

View details →DOI: 10.1016/j.cardfail.2026.04.016
Negative / Null Result ReportMedicine

Longitudinal Associations Among Avoidant/Restrictive Food Intake Disorder Symptoms, Body Dissatisfaction, Restriction, and Suicide Ideation Among Adolescents.

Sahlan RN, Frietchen R, Billman Miller MG et al. · 2025 · Suicide & life-threatening behavior

Objective Although previous research has established bidirectional links between many eating disorder (ED) symptoms and suicidal ideation (SI), no research has examined how symptoms of avoidant/restrictive food intake disorder (ARFID)…

View details →DOI: 10.1111/sltb.70033
Negative / Null Result ReportMedicine

Feasibility of the pre-operative measurement of fractional exhaled nitric oxide and respiratory mechanics to predict respiratory outcomes in children undergoing general anaesthesia.

Hauser N, Sommerfield D, Nguyen J et al. · 2026 · Anaesthesia

Introduction Peri-operative respiratory adverse events remain a major cause of morbidity and mortality in children undergoing general anaesthesia; those with asthma are at higher risk. The aim of this feasibility study was to determine…

View details →DOI: 10.1111/anae.70056
Negative / Null Result Report

Moderating Effects of Intention to Screen on the Relationship Between Attitude Towards Screening and Cancer and High Blood Pressure Screening Uptake Among Nigerians

Fasanu O, Oloruntola FP · 2026 · Preprint

Abstract Background Why is there low behavioural response towards cancer and high blood pressure (HBP) screening uptake among Nigerians? The present study addressed this question by using the theory of planned behaviour (TPB) to…

View details →DOI: 10.21203/rs.3.rs-8836769/v1
Negative / Null Result ReportMedicine

Trajectories and predictors of psycho-social adjustment in patients post hepatocellular carcinoma surgery: A longitudinal study.

Li M, He H, Dong L et al. · 2026 · Journal of psychosomatic research

Background Patients post hepatocellular carcinoma (HCC) surgery encounter physiological challenges as well as psychological and social adaptation problems,yet the trajectory and predictors of their psychosocial adjustment (PSA) remain…

View details →DOI: 10.1016/j.jpsychores.2026.112691
Negative / Null Result ReportMedicine

Death Conceptualizations: How do Youth Presenting to a Pediatric Psychiatric Emergency Department View the End of their Lives?

Tezanos KM, Simeone A, Gerson R et al. · 2026 · Child psychiatry and human development

Youth are presenting to Emergency Departments (EDs) following a suicide-related crisis at higher rates and younger ages. Clinicians lack tools to effectively discern suicide risk in younger patients. The present investigation examines how…

View details →DOI: 10.1007/s10578-026-02006-6
Negative / Null Result ReportMedicine

Prenatal echocardiographic diagnosis and outcomes of fetal sustained supraventricular tachycardia: a ten-year single-center experience.

Ciriello GD, Colonna D, Morelli C et al. · 2026 · Indian pacing and electrophysiology journal

Fetal echocardiography plays a pivotal role in the diagnosis and management of fetal arrhythmias, allowing evaluation of the electrophysiological mechanism and guiding appropriate medical therapy. Herein, we describe our ten-year…

View details →DOI: 10.1016/j.ipej.2026.03.015
Negative / Null Result ReportMedicine

The interdependence of health and grandparenting intensity: A dyadic perspective from grandparent couples in the Health and Retirement Study.

Chan ACY, Stephan AT, Sneed RS · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives While the intensity of grandparent caregiving has been linked to older adults' health, limited research has examined the bidirectional associations between grandparenting intensity and health, particularly within grandparent…

View details →DOI: 10.1093/geronb/gbag022
Negative / Null Result Report

Aging is associated with uniform structural decline across cerebellar regions while preserving topological organization and showing no relation with sensorimotor function

de Witte A, Matthijs A, Nettekoven C et al. · 2026 · Preprint

Aging affects cerebellar structure, yet the regional specificity of this decline and its relationship to sensorimotor function remain unclear. In this study, we quantified age-related gray matter differences in 50 young and 80 older adults…

View details →DOI: 10.64898/2026.02.13.705695
Negative / Null Result ReportMedicine

Guiding connections: The role of therapist interventions in facilitating couples' vulnerability and responsiveness in enactments.

Kula O, Machluf Ruttner R, Shahar B et al. · 2026 · Psychotherapy (Chicago, Ill.)

The primary proposed change process in emotion-focused therapy models for couples involves partners accessing and revealing vulnerable emotions and responding to such disclosures with empathy and compassion. Therapists often use enactments…

View details →DOI: 10.1037/pst0000615
Negative / Null Result Report

Similar exercise adherence and physical fitness outcomes are observed across distinct motivation profiles in older adults participating in a home-based structured exercise programme

Munns A, Feron J, Duda J et al. · 2026 · Preprint

Purpose:Motivation and self-efficacy are established predictors of engagement and persistence within structured exercise programmes; however, it remains unclear whether these psychological factors predict objective adherence metrics and…

View details →DOI: 10.31234/osf.io/gk74p_v2
Negative / Null Result Report

Retrospective Multicenter Analysis of Withdrawal Syndromes After Stimulator Cessation in Parkinson’s Disease Patients with Deep Brain Stimulation

Özden HÖ, Çelik FND, Üstüner FŞ et al. · 2026 · Preprint

Background: Abrupt cessation of deep brain stimulation (DBS) in Parkinson’s disease (PD), most commonly due to implantable pulse generator (IPG) depletion, may lead to DBS withdrawal syndrome (DBS-WDS). However, withdrawal does not occur…

View details →DOI: 10.20944/preprints202601.1856.v1