Negative / Null Result Report
liu p, Hu S, Zeng H et al. · 2026 · Preprint
Abstract Background : Timely reperfusion is critical for patients with acute ST-segment elevation myocardial infarction (STEMI). While door-to-balloon (D2W) time has been substantially optimized in chest pain centers, the impact of first…
View details →DOI: 10.21203/rs.3.rs-8972635/v1 Negative / Null Result ReportMedicine
Arnouts EC, Drysdale ND, Gerstner Saucedo J et al. · 2026 · Pediatric radiology
Background Diffuse myocardial fibrosis, as measured by T1 (longitudinal relaxation time) mapping and extracellular volume, may be associated with ventricular dysfunction in the Fontan circulation. However, the relationship between diffuse…
View details →DOI: 10.1007/s00247-026-06675-2 Negative / Null Result ReportMedicine
Hadi M, Natashia D, Purwati NH et al. · 2026 · Nurse education today
Background Effective interprofessional collaboration is essential for optimal patient care, but inadequate training often hinders teamwork and communication among healthcare professionals. Interprofessional Education (IPE) can address this…
View details →DOI: 10.1016/j.nedt.2026.107138 Negative / Null Result ReportOpen accessMedicine
Levent M, Akın S · 2026 · BMC geriatrics
Background Malnutrition drives adverse outcomes in older adults, but routine screening is often hindered by time constraints and reliance on subjective data. The Geriatric Nutritional Risk Index (GNRI), derived from serum albumin and body…
View details →DOI: 10.1186/s12877-026-07597-2 Negative / Null Result ReportOpen accessMedicine
Li X, Liang L, Yang ZY et al. · 2026 · Translational cancer research
Background Growing evidence suggests that deeply invasive node-negative colon cancer, particularly T4bN0 disease, may have a worse prognosis than early node-positive tumors, challenging the current American Joint Committee on Cancer (AJCC)…
View details →DOI: 10.21037/tcr-2026-0545 Negative / Null Result ReportMedicine
Harding BN, Jiang Z, Pineda D et al. · 2026 · Environmental health : a global access science source
Background The major pathways contributing to cardiovascular disease among night shift workers remain poorly understood. MicroRNAs (miRNAs) have been identified as novel regulators of cardiovascular risk factors. Our objective was to…
View details →DOI: 10.1186/s12940-026-01308-5 Negative / Null Result ReportMedicine
Perrignon C, Baudouin R, Perrignon M et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) is a long-lasting inflammatory disease that affects 1-4% of the population and markedly impairs quality of life, daily functioning, and socio-professional activities. As no…
View details →DOI: 10.1007/s00405-026-10190-3 Negative / Null Result ReportMedicine
Satoh T, Kawaguchi S, Nakatani E et al. · 2026 · Abdominal radiology (New York)
Background/objectives Accurate differentiation between pancreatic carcinoma in situ (CIS) and small invasive pancreatic ductal adenocarcinoma (PDAC) is critical for optimizing patient management. This study aimed to assess the diagnostic…
View details →DOI: 10.1007/s00261-026-05453-w Negative / Null Result ReportMedicine
Acil F, Dedeoğlu A, Tosun Söner H et al. · 2026 · Surgical endoscopy
Background Pneumoperitoneum and steep Trendelenburg positioning during laparoscopic hysterectomy may increase intracranial pressure. Optic nerve sheath diameter (ONSD), measured by transorbital ultrasonography, is a validated noninvasive…
View details →DOI: 10.1007/s00464-026-12731-7 Negative / Null Result ReportMedicine
Lychagin AV, Gritsyuk AA, Elizarov MP et al. · 2026 · Journal of clinical medicine
Background: Robot-assisted total knee arthroplasty (raTKA) improves the precision of component positioning and coronal alignment restoration, but it remains uncertain whether that technical accuracy modifies the clinical effect of…
View details →DOI: 10.3390/jcm15124515 Negative / Null Result ReportMedicine
Damianos JA · 2026 · Clinical biochemistry
Auto-brewery syndrome (ABS) is a rare disorder featuring episodes of intoxication caused by intestinal fermentation of dietary carbohydrates into ethanol. This article presents the case of a patient referred for evaluation of ABS. He…
View details →DOI: 10.1016/j.clinbiochem.2026.111152 Negative / Null Result Report
Dong B, Song Z, Yin Y · 2026 · Preprint
Spatial transcriptomics can reveal localized tumor–immune relationships, but thousands of spots from one tissue section do not provide thousands of biological replicates. We evaluated the distinction between within-section association and…
View details →DOI: 10.64898/2026.06.13.732045 Negative / Null Result Report
Lagacé-Cusiac R, Grahn JA, Ansari D · 2026 · Preprint
Relative magnitudes, such as ratios and proportions, are crucial to everyday life. According to the ratio processing system (RPS) theory, ratios across different formats share a common neural code. Prior neuroimaging studies have shown…
View details →DOI: 10.31234/osf.io/djcsb_v2 Negative / Null Result ReportMedicine
Canivez GL, Watkins MW, McGill RJ et al. · 2026 · Assessment
The Wechsler Adult Intelligence Scale-Fifth Edition (WAIS-5) latent factor structure was assessed using complementary hierarchical exploratory factor analyses (EFA) with the Schmid and Leiman procedure and confirmatory factor analyses…
View details →DOI: 10.1177/10731911251412219 Negative / Null Result ReportMedicine
Yamamoto J, Nakamura K, Hayama H et al. · 2026 · Cardiology
Whether the mortality impact of ischemic stroke and major bleeding differs across left ventricular ejection fraction (LVEF) categories in patients hospitalized for acute heart failure (AHF) with atrial fibrillation (AF) remains uncertain.…
View details →DOI: 10.1159/000553289 Negative / Null Result ReportMedicine
Ricketts TA, Krivoshey R, Santos-Garrido J et al. · 2026 · Journal of speech, language, and hearing research : JSLHR
Purpose The purpose of this study was to evaluate the effects of loudspeaker configuration and relative dialogue-to-background sound levels on subjective ratings of speech understanding and sound quality of recorded media for listeners…
View details →DOI: 10.1044/2026_jslhr-25-00127 Negative / Null Result ReportMedicine
Jee J, Zhang J, Lavery JA et al. · 2026 · Cancer discovery
Real-world data suggest that SARS-CoV-2 mRNA vaccines, administered within 100 days of immune checkpoint inhibitor (ICI) treatment ("peri-ICI vaccination"), may improve ICI effectiveness through synergistic immune priming. In an…
View details →DOI: 10.1158/2159-8290.cd-26-0403 Negative / Null Result ReportMedicine
Maynart V, Menezes P, Batista C et al. · 2026 · Ear and hearing
Abstractobjectives The purpose of this experiment was to determine the effects of sequential sounds on cortical auditory evoked potentials and to investigate temporal masking. The study tested the hypotheses that forward masking reduces…
View details →DOI: 10.1097/aud.0000000000001842 Negative / Null Result ReportMedicine
Li X, Zhang Y, Chen S · 2026 · Journal of counseling psychology
This study examined how clients' outcome expectations (OE; belief about positive outcome of counseling session) was associated with working alliance and symptom relief longitudinally in a sample of Chinese beginning therapist trainees and…
View details →DOI: 10.1037/cou0000879 Negative / Null Result ReportMedicine
Peters EM, Quadri A, Aziz S et al. · 2026 · Journal of affective disorders
The purpose of this study was to examine the effects of two patient-level factors, episode duration and severity, on placebo response in antidepressant clinical trials. To do this we conducted a secondary analysis of seven 8-week,…
View details →DOI: 10.1016/j.jad.2026.122014 Negative / Null Result ReportMedicine
Yan Z, Tian Y, Huang Y et al. · 2026 · Psychopathology
Introduction Distraction response style, neuroticism, and parental conflict have been linked to rumination in adolescents with subthreshold depression. However, whether these associations differ by gender remains unclear. Methods This…
View details →DOI: 10.1159/000552390 Negative / Null Result Report
Su C, Lu T · 2026 · Preprint
Background Heart failure (HF) and body mass index (BMI) share substantial genetic architecture, which may lead genetically informed target discovery to preferentially identify adiposity-related pathways. We sought to identify circulating…
View details →DOI: 10.64898/2026.06.19.26356109 Negative / Null Result ReportMedicine
Howard L, Hawn S, Pitchford KD et al. · 2026 · Behavioral sciences (Basel, Switzerland)
The denial, concealment, or omission of disordered eating behaviors has received limited attention in the eating disorder literature, partly due to the lack of reliable and valid measures. This study re-examined the factor structure of the…
View details →DOI: 10.3390/bs16060898 Negative / Null Result ReportMedicine
Li Y, Chen R, Hou C et al. · 2026 · Medicine
We performed a 2-step Mendelian randomization (MR) study to investigate the associations of Fms-related tyrosine kinase 3 ligand (FLT3L) and phosphate levels with the risk of hypertrophic cardiomyopathy (HCM). Genetic instruments for 75…
View details →DOI: 10.1097/md.0000000000049477 Negative / Null Result ReportMedicine
Aghaalikhani M, Rostami Abusaidi S, Azimi F et al. · 2026 · Journal of medical case reports
Background Osteosarcoma is the most common primary malignant bone tumor, typically affecting adolescents and young adults. While its development is often associated with rapid bone growth and genetic factors, the potential link between…
View details →DOI: 10.1186/s13256-026-06257-8 Negative / Null Result ReportMedicine
Liu Y, Wei M · 2026 · Journal of the Optical Society of America. A, Optics, image science, and vision
Color matching functions (CMFs) play important roles in color specification, characterization, and reproduction. Though the CIE 1931 2° CMFs are widely used in practice, its well-known weaknesses and poor performance have motivated great…
View details →DOI: 10.1364/josaa.590626 Negative / Null Result ReportMedicine
Rahal D · 2026 · Journal of health psychology
Although social support is related to better health, research is mixed regarding how social support relates to physiological systems including the parasympathetic nervous system. The present study assessed whether perceived parental and…
View details →DOI: 10.1177/13591053261430998 Negative / Null Result Report
shakeel h · 2026 · Preprint
Abstract Correct ligand-site assignment is a prerequisite for interpreting molecular dynamics simulations of non-ATP kinase ligands. In computational chemistry and structure-based drug discovery, apparent ligand stability does not by…
View details →DOI: 10.21203/rs.3.rs-9770049/v1 Negative / Null Result ReportMedicine
Li YB, Zheng ZW, Zuo M · 2026 · BMC gastroenterology
Background Total body water (TBW) is an important indicator of fluid homeostasis and is closely related to various metabolic and chronic diseases. However, the relationship between TBW and gastrointestinal symptoms (stomach or intestinal…
View details →DOI: 10.1186/s12876-026-05023-w Negative / Null Result ReportMedicine
Liu P, Dang C, Liu J et al. · 2026 · Current medicinal chemistry
Introduction This study aimed to investigate the causal relationship and biological mechanism between oral contraceptives (OCs) and adverse pregnancy outcomes using Mendelian randomization (MR) methods. Methods We conducted a drug-target…
View details →DOI: 10.2174/0109298673396130260330140027 