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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 605 of 676

Negative / Null Result ReportOpen accessMedicine

Circulating microRNA-219 in stroke: Lack associations with clinical parameters and post-stroke epilepsy risk.

Fahimi Z, Kazemi M, Rahimi H et al. · 2025 · IBRO neuroscience reports

Background Post-stroke epilepsy (PSE) is a significant complication in stroke survivors, yet early diagnostic biomarkers remain unclear. This study investigated whether circulating microRNA-219 (miR-219) could serve as a reliable biomarker…

View details →DOI: 10.1016/j.ibneur.2025.11.013
Negative / Null Result ReportOpen accessMedicine

The impact of meteorological conditions on the occurrence of low back pain in a retrospective registry based population study.

Ochal M, Lewczuk KG, Dragańska E et al. · 2026 · Scientific reports

Low back pain (LBP) is one of the most prevalent musculoskeletal complaints and a leading cause of disability worldwide. Although patients frequently attribute symptom exacerbation to adverse weather, the scientific evidence for a direct…

View details →DOI: 10.1038/s41598-026-40669-2
Negative / Null Result ReportMedicine

Perioperative N-acetylcysteine: evidence and indications.

Wilson PR, Bridges KH, Scofield M et al. · 2024 · Pain management

Nonopioid analgesics serve to improve analgesia and limit side effects and risks of perioperative opioids. N-acetylcysteine (NAC), the primary treatment of acetaminophen toxicity, may have perioperative indications, including analgesia.…

View details →DOI: 10.1080/17581869.2024.2388504
Negative / Null Result ReportMedicine

Has stopping stopped making sense? Disentangling the processes elicited by complex action cancellation paradigms.

Weber S, Kemp SA, Hinder MR · 2026 · Cognitive, affective & behavioral neuroscience

Action cancellation represents a fundamental aspect of human motor control. Nonetheless, the behavioural paradigms used to study it are methodologically diverse and capture an incompletely understood combination of processes. Advancing…

View details →DOI: 10.3758/s13415-026-01440-2
Negative / Null Result Report

Re-examining the effect of inoculation messages on anti-vaccine conspiracy attitudes: A conceptual replication of Banas et al (2023)

Adinugroho I, Bentall R, Stafford T · 2025 · Preprint

This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…

View details →DOI: 10.31234/osf.io/d3x9p_v2
Negative / Null Result Report

Ranschburg Unrepeated

Remouchamps R, Majerus S, Kowialiewski B · 2025 · Preprint

In verbal working memory (WM), the second occurrence of an item in a memory list generally leads to impaired recall performance, a phenomenon called the “Ranschburg effect”. One explanation for this effect is response suppression, by which…

View details →DOI: 10.31234/osf.io/3zmje_v1
Negative / Null Result ReportMedicine

Newborn Auditory Brainstem Response and Sudden Infant Death Syndrome.

Maylott SE, Zeng G, Leung TS et al. · 2025 · Journal of neuroscience research

Sudden infant death syndrome (SIDS)-the sudden and unexplained death of a seemingly healthy infant, < 1 year old-may be associated with abnormalities in the brain regions that underlie breathing and arousal during sleep. While post-mortem…

View details →DOI: 10.1002/jnr.70083
Negative / Null Result ReportOpen accessMedicine

Shedding light on public perceptions of scientists who engage in wrongness admission amidst a failed replication.

Evans ND, Fetterman AK · 2026 · Public understanding of science (Bristol, England)

Admitting that one's research findings are wrong involves admitting a potential instance of incompetence, which can keep scientists from engaging in wrongness admission. However, wrongness admission can yield favorable perceptions. In five…

View details →DOI: 10.1177/09636625251372820
Negative / Null Result ReportMedicine

Towards distinguishing intra-canal and paraspinal cavitation activity during focused ultrasound exposures in the spine.

Frizado AP, O'Reilly MA · 2025 · Physics in medicine and biology

Objective. Although less established than transcranial focused ultrasound (FUS), transvertebral FUS is being developed to treat spinal cord pathologies. Transvertebral sonication of the spinal cord for microbubble-mediated drug delivery…

View details →DOI: 10.1088/1361-6560/ae0f36
Negative / Null Result Report

Ptbp1 is not required for retinal neurogenesis and cell fate specification

Appel H, Carmen-Orozco RP, Santiago CP et al. · 2025 · Preprint

The RNA-binding protein Ptbp1 has been proposed as a master regulator of neuronal fate, repressing neurogenesis through its effects on alternative splicing and miRNA maturation. While prior studies using RNA interference suggested that…

View details →DOI: 10.1101/2025.07.02.662808
Negative / Null Result ReportMedicine

Biodegradable mesh implants for prolapse repair: Advances in computational modelling and experimental validation.

Vaz F, Silva T, Silva E et al. · 2025 · Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine

Pelvic organ prolapse (POP) limits people's quality of life and is quite common in women, especially with advancing age. As cases increase, there is an urgent need for alternative treatments, especially for severe POP, where options remain…

View details →DOI: 10.1177/09544119251323336
Negative / Null Result Report

Is mental effort exertion contagious? A replication study

Mazza A, Voorrips E, Hughes G et al. · 2024 · Preprint

Daily, we perform activities in the presence of others (e.g., office work). While it's well-established that the mere presence of others can influence our performance, it is less clear whether others' performance, rather than just their…

View details →DOI: 10.31234/osf.io/fgcu6
Negative / Null Result Report

Belief change and the concept of Free Will

Tavernier N, Wisniewski D, Brass M · 2024 · Preprint

Over the last 15 years, researchers in psychology asserted that manipulating laypeople’s free will beliefs (FWB) has an impact on various downstream social behaviors (such as cheating). More recently, however, many of these findings failed…

View details →DOI: 10.31234/osf.io/sh2mr
Negative / Null Result ReportMedicine

Influence of rhythmic contexts on perception: No behavioral and eye-tracker evidence for rhythmic entrainment.

Román-Caballero R, Martín-Arévalo E, Martín-Sánchez PDC et al. · 2024 · Consciousness and cognition

Entrainment theories propose that attention inherently oscillates between moments of attentional enhancement and disengagement. Consequently, perceptual and response benefits have been reported in tasks with a rhythmic structure. In the…

View details →DOI: 10.1016/j.concog.2024.103789
Negative / Null Result ReportMedicine

Using a naive Bayesian approach to identify academic risk based on multiple sources: A conceptual replication.

Oddleifson C, Kilgus S, Klingbeil DA et al. · 2025 · Journal of school psychology

The purpose of this study was to conduct a conceptual replication of Pendergast et al.'s (2018) study that examined the diagnostic accuracy of a nomogram procedure, also known as a naive Bayesian approach. The specific naive Bayesian…

View details →DOI: 10.1016/j.jsp.2024.101397
Negative / Null Result ReportMedicine

No transfer of 3D-Multiple Object Tracking training on game performance in soccer: A follow-up study.

Romeas T, Goujat M, Faubert J et al. · 2025 · Psychology of sport and exercise

The impact of domain-general cognitive 'brain' training on improving sports performance is highly debated. This study sought to follow-up on research that showcased the benefits of perceptual-cognitive 3D-Multiple Object Tracking (3D-MOT)…

View details →DOI: 10.1016/j.psychsport.2024.102770
Negative / Null Result Report

Influence of rhythmic contexts on perception: No behavioral and eye-tracker evidence for rhythmic entrainment

Román-Caballero R, Martín-Arévalo E, Martín-Sánchez PdC et al. · 2024 · Preprint

Entrainment theories propose that attention inherently oscillates between moments of attentional enhancement and disengagement. Consequently, perceptual and response benefits have been reported in tasks with a rhythmic structure. In the…

View details →DOI: 10.31234/osf.io/vt6zy