A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20261 results in Negative / Null Result Report · page 603 of 676
Marshall MJ, Peck K, Hunter R et al. · 2024 · Behavioral sciences (Basel, Switzerland)
Eysenck's biopsychological model of stress posits that the extraversion-introversion distinction is associated with different thresholds of arousal, which in turn moderate the stress response. Although higher thresholds of activation have…
Gow J, Roofeh D · 2025 · Preprint
Abstract Background: Giant cell arteritis (GCA) is a large vessel vasculitis characterized by granulomatous inflammation classically affecting the carotid artery branches. GCA most often presents with one or more classic clinical features…
Graf J, Buder A · 2025 · Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
Primary erythrocytosis, also known as polycythemia vera, is a myoproliferative disease resulting in an increased red blood cell mass and is associated with increased hematocrit and hemoglobin concentrations. Patients have an augmented risk…
Khalifa H, Ayaty M, Oreaba R et al. · 2025 · Journal of the Egyptian National Cancer Institute
Objectives Following external beam radiation therapy (EBRT) with concurrent chemotherapy, we analyzed the benefits of surgical resection for locally advanced cervical carcinoma in terms of the frequency and severity of complications and…
Lyu HH, Wen X, Lin JT et al. · 2025 · Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
Objective: To compare the Kadish T staging, AJCC T staging, and Dulguerov T staging system in terms of their impact on surgical treatment selection and survival prognosis in patients with olfactory neuroblastoma (ONB). Methods: The cases…
Chen PY, Young TC, Lin CY et al. · 2025 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Objective To determine the hearing outcomes in patients with sudden sensorineural hearing loss (SSNHL) after exposure to different brands of vaccines against COVID-19. Study design Cohort study. Setting Tertiary referral center. Patients…
Zheng X, Zhang T, Zhan T et al. · 2025 · Respiratory medicine
Purpose Positive end-expiratory pressure (PEEP) refers to a vital respiratory therapeutic tool for treating ARDS. Since overweight individuals face a greater risk of pulmonary complications than others, this study aims to assess whether…
Syed-Abdul MM, Tian L, Hegele RA et al. · 2025 · The lancet. Diabetes & endocrinology
There is a well-established link between the severity of hypertriglyceridaemia and acute pancreatitis and long-term triglyceride-lowering therapies known to prevent episodes of acute pancreatitis. Therefore, it has been assumed, without…
Nas OF, Kandemirli SG, Korkmaz B et al. · 2025 · Neurological research
Objectives To evaluate success, complications and efficacy for endovascular management for carotid blowout syndrome. Methods Images were evaluated for contrast extravasation, vessel wall irregularity, pseudoaneurysm/aneurysm formation.…
Bruillot M, Pieper A, Sourd D et al. · 2025 · European journal of anaesthesiology
Background Treatment programs designed to enhance recovery after caesarean delivery include multimodal analgesia to ensure optimal analgesia while reducing exposure to systemic opioids. Evidence for the effectiveness of continuous wound…
Domin M, Liew SL, Hordacre B et al. · 2025 · NeuroImage
Indirect structural disconnection-symptom mapping allows white matter impairment to be determined without the need for multi-directional diffusion (MDDW) imaging for each individual. Although widely used this method has not been validated.…
Trost SU, Harindhanavudhi T, Lang Q et al. · 2024 · Preprint
Background: The approval of cystic fibrosis conductance regulator (CFTR) modulators including the triple modulator Elexacaftor/Tezacaftor/Ivacaftor (ETI) for people with cystic fibrosis (pwCF) have improved pulmonary function…
Bhatt HV, Patel D, Rogando D et al. · 2025 · Annals of cardiac anaesthesia
Although thoracic epidural analgesia and paravertebral blocks have well-documented benefits in cardiac surgery, the theoretical risk of neuraxial hematoma in anticoagulated patients limits their use. Fascial plane blocks are recently…
Wattanathorn J, Muchimapura S, Thukham-Mee W et al. · 2025 · Life (Basel, Switzerland)
Owing to the need for a brain supplement targeting neuroprotection against age-related brain disorders and the known effect of carotenoids on brain function, we aimed to assess the effect of consuming carotenoid-rich functional congee for…
Lao J, Wei Y, Liu F et al. · 2025 · European journal of nutrition
Purpose Currently, there is controversy surrounding the association between dietary fatty acids (FAs) and ovarian cancer (OC) risk. We aimed to elucidate the aforementioned topic using data from a large cohort. Methods Women participating…
Weber K, Magnenat L, Morier S et al. · 2024 · Preprint
Abstract Background The reduction of violence risk and crime recidivism is the core marker of progress in forensic psychiatry treatment for mentally disordered offenders, and commonly used to decide prison release. While dynamic risk is…
Ahmed A, Ahmed A, Zahra Z et al. · 2025 · Physiology & behavior
Introduction Despite emerging evidence on oxytocin's role in eating disorders,there is a need for a comprehensive review to integrate findings across neurobiological, genetic, hormonal, and therapeutic dimensions. This scoping review…
Ingram I, Hughes MA · 2024 · Journal of laparoendoscopic & advanced surgical techniques. Part A
Background: Surgeons are exposed to unavoidable distractions while operating. Distractions can cause stress, and stress can impair cognition and motor skills to the detriment of surgeon performance. This study assessed the impact of…
Zhang Y, Wen Z, Xia C et al. · 2024 · Heliyon
Dyslipidemia has been implicated in autoimmunity; however, its association with myasthenia gravis (MG) prognosis is unclear. We aimed to investigate the correlation between baseline lipid profiles and risk of MG worsening. This 7-year…
Williams KJ · 2025 · Current opinion in lipidology
Purpose of review For many years, inflammation has been a major concept in basic research on atherosclerosis and in the development of potential diagnostic tools and treatments. The purpose of this review is to assess the performance of…
Demir S, KÖYLÜ MT · 2023 · Preprint
INTRODUCTION To examine the ability of changes in optical coherence tomography angiography (OCTA) values to predict progression in the visual field (GA) and retinal nerve fiber layer (RNFL) in patients with glaucoma progression. METHODS…
Basu S, Gupta S, De R et al. · 2024 · Preprint
ABSTRACT Background and Objectives Microcytic hypochromic anemia is the most common feature of alpha-thalassemia and depends on the number of alpha genes deleted. Therefore, in this study, we aim to determine the most common deletion…
Kaşkal M, Bucci T, Alobaida M et al. · 2025 · European journal of clinical pharmacology
BACKGROUND: Chronic pericarditis is associated with significant cardiovascular morbidity, including atrial fibrillation (AF), heart failure (HF), and stroke. Colchicine is widely used in pericarditis management for its anti-inflammatory…
Koivunen P · 2026 · Current opinion in otolaryngology & head and neck surgery
Purpose of review Systematic follow-up protocols, often including regular imaging, are an essential component of posttreatment care for head and neck cancer, aimed at the early detection of disease relapse and mitigating treatment-related…
Luo L, Zhang Z, Zeng H et al. · 2025 · Journal of gastrointestinal oncology
Background The prognosis of patients with gastric cancer with peritoneal metastasis (GCPM) is exceedingly poor. This study evaluated the efficacy and safety of hyperthermic intraperitoneal chemotherapy (HIPEC) with paclitaxel combined with…
Sewell KM, Oriakhi K, Ngo Tenlep SY et al. · 2026 · Ecotoxicology and environmental safety
Organophosphate flame retardants (OPFRs) are used in many consumer products, and their presence in our environment raises concerns about potential health dangers. In humans, exposure to OPFRs, such as tris(1,3-dichloro-2-propyl) phosphate…
Kotha S, Baisya R, Yerram KV et al. · 2025 · Mediterranean journal of rheumatology
Background Lupus enteritis (LE) is the most common serious gastrointestinal manifestation of SLE. Indian literature on LE is limited, while most of the data comes from China and Western series with recent efforts on developing prediction…
Gow J, Roofeh D · 2025 · BMC rheumatology
Background Giant cell arteritis (GCA) is a large vessel vasculitis characterized by granulomatous inflammation classically affecting the carotid artery branches. GCA most often presents with one or more classic clinical features which…
Patel SA, Roy JM, Musmar B et al. · 2024 · Neurosurgical focus
Objective Preclinical studies suggest that robotic carotid artery stenting (CAS) could be superior to manual CAS. However, very limited comparative data exist for patients who have undergone robotic versus manual CAS. In addition, no data…
Goudman L, Pilitsis JG, Billet B et al. · 2024 · Anaesthesia
The numerical rating scale and visual analogue scale are used to quantify pain intensity. However, it has not yet been explored whether these scores are interchangeable in adults with chronic pain. Data from the prospective multicentre…