Replication FailureOpen accessBiotechnology
Nozomi Maniwa, Samuel Porfirio Xavier, Sergio Luis Scombatti de Souza et al. · 2024 · Journal of Functional Biomaterials
Background: A comprehensive investigation to associate the use of polynucleotides and hyaluronic acid with bovine bone in maxillary sinus lift procedures in rabbits has not been performed yet. The aim was to evaluate the influence of this novel association on the processes of bone regeneration in maxillary sinus augmentation. Methods: In this prospective, randomized, within-animal model, maxillary sinus augmentation was performed bilaterally in 12 rabbits. Deproteinized bovine bone material (DBBM) was used as filler material. A hyaluronic acid–polynucleotide gel was aggregated at the test site
View details →DOI: 10.3390/jfb15120361 Replication FailureOpen accessMedicine
Md Habibul Ghani, Md. Shahed Morshed, Tahniyah Haq et al. · 2023 · Bangabandhu Sheikh Mujib Medical University Journal
Hypovitaminosis D (<20 ng/mL) is thought to increase insulin resistance and meta-inflammation contributing to the pathogenesis of diabetes mellitus (DM). Correcting vitamin D deficiency in people with prediabetes might halt its progression to DM. The aim of this study was to examine the effect of vitamin D supplementation on insulin resistance, glycemic status, and inflammation in prediabetic adults with vitamin D deficiency. This doubleblind randomized placebo-controlled trial was done among 27 newly detected prediabetic adults with hypovitaminosis D randomly assigned to 60,000 IU of vitamin
View details →DOI: 10.3329/bsmmuj.v15i3.62956 Replication FailureOpen accessInfectious and parasitic diseases
Edlin Brian R, Yeager Meredith, Xiao Nianqing et al. · 2008 · BMC Infectious Diseases
Abstract Background Genetic variations in MBL2 that reduce circulating levels and alter functional properties of the mannose binding lectin (MBL) have been associated with many autoimmune and infectious diseases. We examined whether MBL2 variants influence the outcome of hepatitis C virus (HCV) infection. Methods Participants were enrolled in the Urban Health Study of San Francisco Bay area injection drug users (IDU) during 1998 through 2000. Study subjects who had a positive test for HCV antibody were eligible for the current study. Participants who were positive for HCV RNA were frequency ma
View details →DOI: 10.1186/1471-2334-8-57 Replication FailureOpen accessNutrition. Foods and food supply
Ziqi Sang, Ziqi Sang, Han Wang et al. · 2025 · Frontiers in Nutrition
BackgroundHepatic fibrosis and the fatty liver index (FLI) are critical indicators for assessing the progression and severity of metabolic dysfunction-associated steatotic liver disease (MASLD) and serve as valuable reference markers for predicting MASLD-related risks. The Dietary Inflammation Index (DII) quantifies the inflammatory effects of dietary intake and has been extensively utilized in nutritional and epidemiological studies. Although studies have been conducted to confirm the correlation between dietary quality and MASLD in the general population, this study sought to further explore
View details →DOI: 10.3389/fnut.2025.1594192 Replication FailureOpen accessMedicine
Karina da Silva, Cristino Carneiro Oliveira, Leandro Ferracini Cabral et al. · 2023 · PLoS ONE
Pulmonary expansion manoeuvres are therapeutic techniques used to prevent and reverse atelectasis; however, no randomized controlled trials have provided evidence supporting the use of this intervention among individuals on mechanical ventilation. Objective To evaluate the effects of chest compression-decompression and chest block manoeuvres compared to usual care among patients on mechanical ventilation. Methods The current study was a randomized clinical trial of adult subjects on mechanical ventilation for 12 to 48 hours. The control group received usual care (passive or active mobilization
View details →DOI: 10.1371/journal.pone.0295775 Replication FailureOpen accessPsychology
Alba Massolo, Mariel Traversi, Matías Alfonso · 2024 · Europe's Journal of Psychology
In this paper, we investigate whether collaborative group performance is better than individual performance in solving a syllogism evaluation task. We hypothesise that collaborative group settings will outperform individual settings and that the belief bias effect will be mitigated in a group setting. Two empirical studies were conducted with Argentinian undergraduate students. Study 1 (N = 239) used a between-subjects design with two conditions: individual resolution and interactive group resolution. Overall, the group condition performed better than the individual condition, but there were n
View details →DOI: 10.5964/ejop.12041 Replication FailureOpen accessMedicine
Tatsuya Nagano, Masashi Hashimoto, Shintaro Izumi et al. · 2024 · Scientific Reports
Abstract Previously reported oropharyngeal exercises are long and difficult to perform. Therefore, we created a 10-min daily oropharyngeal exercise program and conducted a study to confirm its effectiveness. Twenty-five participants whose apnoea–hypopnoea index (AHI) values were greater than 5 were enrolled. All of the participants performed 10 min of exercise per day for 12 weeks and were evaluated for AHI values, tongue pressure, lip closure pressure, snoring, and Mallampati scores before and after the exercise. Twenty-two participants (88% of all participants) completed the oropharyngeal ex
View details →DOI: 10.1038/s41598-024-79884-0 Replication FailureOpen accessSpecialties of internal medicine
Pooja Budhiraja, Rocio Lopez, Rocio Lopez et al. · 2025 · Transplant International
This study compares outcomes between Simultaneous Pancreas-Kidney Transplantation (SPKT) and Deceased Donor Kidney Transplantation (DDKT) in recipients with diabetes, assessing survival benefits against surgical and immunological risks. We analyzed Scientific Registry of Transplant Recipients data (2014–2023) to assess patient and kidney graft survival. Overlap propensity score weighting was applied to adjust for group differences. Kaplan-Meier and Cox proportional hazards models were used to estimate survival outcomes in unadjusted, covariate-adjusted, and weighted analyses. Among 22,545 reci
View details →DOI: 10.3389/ti.2025.14934 Replication FailureOpen accessMedicine (General)
Parsa Mohammadi, Elaheh Karimi, Adeleh Maleki et al. · 2022 · Acta Medica Iranica
Accumulating evidence suggests the potential use of chloroquine, an anti-malaria medication, as a neuroprotective agent. Moreover, several studies have reported that the endogenous opioids and nitric oxide (NO) may mediate the chloroquine’s effects. In the present study, effects of chloroquine on hyoscine-induced memory impairment were assessed. Furthermore, the possible involvements of opioids and NO were evaluated. Chloroquine was administered intraperitonially (i.p.) at doses of 0.1, 0.5, 1, 3, 10, and 20 mg/kg to hyoscine-treated (1mg/kg, i.p.) mice, and the spatial and fear memories were
View details →DOI: 10.18502/acta.v60i2.8819 Replication FailureOpen accessDiseases of the endocrine glands. Clinical endocrinology
Quoc Huy Hoang, Hung Sy Ho, Huong Thuy Do et al. · 2021 · Reproductive Medicine and Biology
Abstract Purpose This study compared the therapeutic effects of transdermal testosterone gel (TTG) application at 4 and 6 weeks before controlled ovarian hyperstimulation (COH) in women with poor ovarian response (POR). Methods In this randomized control trial, infertile women with POR who underwent in vitro fertilization (IVF) were recruited and randomly classified into 4 week (n = 42) and 6 week (n = 38) TTG treatment groups and control group (n = 42). The primary outcome was total number of retrieved mature oocytes. The secondary outcomes were the biochemical pregnancy rate, clinical pregna
View details →DOI: 10.1002/rmb2.12383 Replication FailureOpen accessMedicine
Hassan Rezvanian, Ali Kachuei, Ali Mirzapour · 2011 · مجله دانشکده پزشکی اصفهان
Background: Milk thistle has antioxidative effects and may improve renal performance. Our study investigated whether Milk thistle improve renal performance in patients with type II diabetes mellitus nephropathy. Methods: In this clinical trial study, after ethics committee approval, 65 Patients with type II diabetes mellitus were enrolled into a randomized simple sampling, prospective, double-blinded study. In the case group, was gave Milk thistle and control group was given placebo. We measured urine albumin/cratinine (A/C) ratio and eGFR before and after intervention. The gathered data were
Replication FailureOpen accessDiseases of the digestive system. Gastroenterology
Ben-Gang Zhou, Ming-Wen Guo, Li-Juan Zhang et al. · 2024 · Therapeutic Advances in Gastroenterology
Background: The efficacy of the 14-day esomeprazole–amoxicillin (EA) dual therapy in eradicating Helicobacter pylori ( H. pylori ) has been widely discussed previously. Vonoprazan, a novel potassium-competitive acid blocker, presents rapid, potent, and long-lasting acid inhibitory effects compared to esomeprazole. However, there is currently a scarcity of direct comparisons between the 10-day vonoprazan–amoxicillin (VA) and the 14-day EA dual therapy for H. pylori eradication. Objectives: This study aimed to compare the efficacy and safety of the 10-day VA and the 14-day EA dual therapy for H.
View details →DOI: 10.1177/17562848241309870 Replication FailureOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
N. V. Dmitrieva, M. V. Eidelshtein, V. V. Aginova et al. · 2019 · Сибирский онкологический журнал
The purpose of the study was to evaluate the frequency of isolation of multi-resistant Pseudomonas aeruginosa and identify the mechanisms of resistance to carbapenems.Material and methods. We analyzed 866 strains of Pseudomonos aeruginosaisolated from clinical samples from cancer patients in the period 2014–2016. the level of resistance to piperacillin/tazobactam, ceftazidime, cefepime, imipenem, meropenem, ciprofloxacin, amikacin in dynamics was determined. carbapenem-resistant (car-R) strains were examined for the presence of enzymes.Results. Between 2014 and 2016, the number of strains resi
View details →DOI: 10.21294/1814-4861-2019-18-2-28-34 Replication FailureOpen accessAstrophysics
J. Ming, M. A. Papa, H.-B. Eggenstein et al. · 2024 · The Astrophysical Journal
We perform a search for continuous nearly monochromatic gravitational waves from the central compact objects associated with the supernova remnants Vela Jr. and G347.3. Over 10 ^18 different waveforms are considered, covering signal frequencies between 20 and 1300 Hz (20 and 400 Hz) for G347.3-0.5 (Vela Jr.) and a very broad range of frequency derivatives. The data set used for this first search is from the second observing run of LIGO (O2). Thousands of volunteers donating compute cycles through the computing project Einstein@Home have made this endeavor possible. Following the Einstein@Home
View details →DOI: 10.3847/1538-4357/ad8b9e Replication FailureOpen accessNuclear and particle physics. Atomic energy. Radioactivity
The CMS collaboration, A. Hayrapetyan, A. Tumasyan et al. · 2025 · Journal of High Energy Physics
Abstract Results are presented for a test of the compositeness of the heaviest charged lepton, τ, using data collected by the CMS experiment in proton-proton collisions at a center-of-mass energy of 13 TeV at the CERN LHC. The data were collected in 2016–2018 and correspond to an integrated luminosity of 138 fb −1. This analysis searches for tau lepton pair production in which one of the tau leptons is produced in an excited state and decays to a ground state tau lepton and a photon. The event selection consists of two isolated tau lepton decay candidates and a high-energy photon. The mass of
View details →DOI: 10.1007/jhep06(2025)006 Replication FailureOpen access
· 2021 · Indonesian Treasury Review: Jurnal Perbendaharaan, Keuangan Negara dan Kebijakan Publik
This study examines the effects of fiscal decentralization, internal audit capability, bureaucratic reform, and performance accountability on corruption that occur in local governments. Corruption in this research was measured by the…
View details →DOI: 10.33105/itrev.v6i4.410 Replication FailureOpen access
Ela Miranda, Iriani Iriani, I. Nasution · 2022 · JRMB (Jurnal Riset Manajemen & Bisnis)
The high income tax expense causes the company to carry out earnings management. Decreased earnings management tends to result in high tax planning. The company's ability to pay off short-term liabilities by using good current assets…
View details →DOI: 10.30743/jrmb.v7i1.5709 Replication FailureOpen access
Elsiaulavita Gracia, S. Nurohman, I. Wilujeng · 2024 · Jurnal Penelitian Pendidikan IPA
This study aims to analyze the impact of applying the STEAM (Science, Technology, Engineering, Arts, Mathematics) approach in science education on students' creative thinking skills. The STEAM approach offers an integration of various…
View details →DOI: 10.29303/jppipa.v10i11.7782 Replication FailureOpen accessMedicine
A. Bühler, Johannes Thrul, Evelin Strüber et al. · 2015 · Health Promotion International
Because of scarce research, the effectiveness of substance abuse prevention in leisure settings remains unclear. In this study, we evaluated the effectiveness of a peer-led educational prevention measure with adolescent groups in…
View details →DOI: 10.1093/heapro/dav007 Replication FailureMedicine
Meerman M, Buijser M, Neto AS et al. · 2026 · Critical care medicine
Objectives To determine whether perioperative IV magnesium sulfate infusion, targeting serum magnesium concentrations of 1.5-2.0 mmol/L, reduces the incidence of postoperative atrial fibrillation (POAF) in patients undergoing cardiac…
View details →DOI: 10.1097/ccm.0000000000007162 Replication FailureOpen accessDiseases of the genitourinary system. Urology
Wanqing Huang, Jiuxu Bai, Yanping Zhang et al. · 2024 · Renal Failure
Background Elderly hemodialysis (HD) patients have a high risk of death. The effect of different types of HD membranes on survival is still controversial. The purpose of this study was to determine the relationship between the use of low-flux or high-flux membranes and all-cause and cardiovascular mortality in elderly hemodialysis patients.Methods This was a retrospective clinical study involving maintenance hemodialysis patients which were categorized into low-flux and high-flux groups according to the dialyzer they were using. Propensity score matching was used to balance the baseline data o
View details →DOI: 10.1080/0886022x.2024.2338217 Replication FailureMedicine
Elenjickal EJ, Mavrakanas TA · 2026 · American journal of nephrology
Background Aldosterone regulates genes controlling fluid and electrolyte balance through mineralocorticoid receptor (MR) activation. Sustained MR activation promotes inflammation, fibrosis, sodium retention, and myocardial remodeling. MR…
View details →DOI: 10.1159/000551881 Replication FailureMedicine
Alallah J, Mohtisham F, Ahmed A et al. · 2026 · Journal of neonatal-perinatal medicine
BackgroundThe study examined the medical impact of tahneek with dates on hypoglycemia in high-risk newborns. Tahneek, an Islamic tradition, may offer benefits such as stimulating mouth muscles and aiding in breastfeeding initiation. The…
View details →DOI: 10.1177/19345798261435496 Replication FailureOpen accessMedicine
Gangeri L, Alfieri S, Anselmi V et al. · 2025 · Tumori
Background As part of the improvement plan of the Organisation of European Cancer Institutes at the Fondazione IRCCS Istituto Nazionale dei Tumori of Milan (INT) a Committee composed of patients, caregivers, and representatives of patient…
View details →DOI: 10.1177/03008916251346564 Replication FailureOpen accessGeriatrics
Anum Zahra, Maarten van Smeden, Petra J. M. Elders et al. · 2025 · BMC Geriatrics
Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. Due to their frailty status, comorbidity burden can serve as a useful predictive indicator of vulnerability in this frail population. However, the prognostic value of these cumulative comorbidity scores like the Charlson comorbidity index (CCI) remained unclear in this population. We evaluated the incremental predictive value of the CCI for predicting 28-day mortality in NH residents with COVID-19, compared to prediction using age and sex only. Methods
View details →DOI: 10.1186/s12877-025-05721-2 Replication FailureMedicine
Ye C, Sheng Y, Zhang X et al. · 2026 · Plant Science.
Gene editing has emerged as a powerful tool in crop breeding, particularly for rice, enabling the creation of germplasm and trait improvement. A thorough understanding of gene functions is essential for precise and efficient crop…
Replication FailureOpen accessMedicine
Medeiros CNA, Azevedo IG, Gomes Fernandes SG et al. · 2026 · PeerJ
Background Urinary incontinence (UI) is a common complaint among middle-aged and older women, associated with many negative impacts in health. The aim of this study was to analyze whether an association exists between UI and sarcopenic…
View details →DOI: 10.7717/peerj.20470 Replication FailureMedicine
Awwad A, Das Adhikari U, Burdo TH et al. · 2026 · AIDS (London, England)
Objective To determine whether pitavastatin reduces enterocyte injury, assessed by intestinal fatty acid-binding protein (I-FABP), among antiretroviral therapy-treated people with HIV (PWH) enrolled in the REPRIEVE mechanistic substudy.…
View details →DOI: 10.1097/qad.0000000000004572 Replication FailureOpen accessMedicine
Tidblad L, Öberg Sysojev A, Delcoigne B et al. · 2025 · RMD open
Objective To examine whether obesity and/or overweight are independently associated with an increased risk of remission failure in patients with early rheumatoid arthritis (RA), treated with methotrexate as first disease-modifying…
View details →DOI: 10.1136/rmdopen-2025-005430 Replication FailureOpen accessMedicine
Alevi KCC, Ravazi A, de Oliveira J et al. · 2025 · Scientific reports
The diversification of Rhodnius species has been primarily attributed to vicariance events. Phylogenomic studies have proposed various evolutionary hypotheses - such as incomplete lineage sorting, hybrid speciation, and introgression - to…
View details →DOI: 10.1038/s41598-025-29472-7 