A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20261 results in Negative / Null Result Report · page 597 of 676
Wentink N, van Gent M, Borns C · 2026 · The British journal of radiology
Objectives To quantify the reduction in effective dose achieved through organ dose modulation (ODM) on a General Electric Revolution Apex CT scanner, while preserving image quality. Methods First, the noise index (NI) corresponding to…
Pomierska M, Milska-Musa KA · 2026 · Preprint
Introduction: Pregnancy comes with many physical and mental changes, which can affect one’s sexual satisfaction, body image and general well-being. The aim of the study was to analyse these variables.Material and methods: The study was…
Abid R, Murphy RF, Hogue GD et al. · 2026 · Journal of pediatric orthopedics
Background Treatment options for early-onset scoliosis (EOS) are confounded by the risks associated with intervention at a younger age. Spinal instrumentation must be considered carefully due to potentially adverse effects to the spine,…
Hooper L, Erridge S, Clarke E et al. · 2026 · Brain and behavior
Introduction Migraine is a primary headache disorder, which leads to diminished health-related quality of life (HRQoL). There is limited evidence assessing efficacy of cannabis-based medicinal products (CBMPs) for migraine. This study…
Kato T, Motokawa T, Seto S et al. · 2026 · Preprint
Abstract Background Smartphone-based mental health applications are increasingly used for stress self-management; however, evidence from real-world settings remains limited, particularly for interventions combining subjective and…
Chaudhary H, Saeed S, Carroll A · 2026 · Irish medical journal
Aim This retrospective study aimed to evaluate changes in body mass index (BMI) and haemoglobin A1c (HbA1c) levels among children and adolescents with type 1 diabetes mellitus (T1DM) transitioning from multiple daily injections (MDI) to…
Fuse Y, Tsukada N, Yamaguchi M et al. · 2026 · Biological trace element research
Adequate iodine intake is essential for maintaining thyroid function. School meal iodine content (SMIC) is one of the main sources of iodine for schoolchildren. The median urinary iodine concentration (mUIC) in spot urine samples is a…
Kwaiser MM, King JF, Troyer LE et al. · 2026 · Preprint
Abstract Background Many physical activity interventions exist, but few are sustained, with additional barriers in rural populations. The primary objective was to evaluate the feasibility of a refined implementation strategy for a…
Diego-Navarro O, Copete S, Moreno-Martínez A et al. · 2026 · European journal of ophthalmology
PurposeTo evaluate functional and anatomical outcomes after intravitreal dexamethasone implant (DEXI) in macular edema secondary to retinal vein occlusion (ME-RVO), comparing treatment-naïve eyes with early-switch (ES) and late-switch (LS)…
Şafak A, Karakaya E, Yıldırım S et al. · 2026 · Transplantation proceedings
Introduction Although liver biopsy in patients with acute cellular rejection (ACR) is the gold standard for diagnosis, its invasive nature highlights the need for reliable noninvasive biomarkers. With evidence suggesting that peripheral…
Parapiboon W, Pattanapongpaibool A, Sanprasert S · 2026 · International urology and nephrology
Purpose The benefits of incremental peritoneal dialysis (IPD) with days off remain controversial. This study aimed to compare the survival rate between IPD with days off and standard-dose peritoneal dialysis (PD). Methods Participants who…
Musbahi O, Pouris K, Hadjixenophontos S et al. · 2025 · World journal of methodology
Background Relieving pain is central to the early management of knee osteoarthritis, with a plethora of pharmacological agents licensed for this purpose. Intra-articular corticosteroid injections are a widely used option, albeit with…
Bushaibah O · 2026 · Environmental monitoring and assessment
Understanding long-term microbial dynamics in semi-enclosed coastal systems is essential for evaluating wastewater-related impacts and informing management responses. This study applies an integrated nonparametric diagnostic framework to…
Alatrash M, Moustafa MS, Nashed GA et al. · 2026 · Preprint
Background: The gallbladder plays an essential role in lipid homeostasis through bile storage and regulated release. Gallstone disease is frequently associated with dyslipidemia, and cholecystectomy is one of the most common abdominal…
Torres K, Terzi S, Simón L · 2026 · Scientific reports
Healthier diets are associated with fewer mental health symptoms, whereas higher consumption of ultra-processed foods is associated with psychological distress. This pilot study aimed to evaluate the impact of a nutrition education…
Aytekin AM, Ulusoy HE, Efe MA et al. · 2026 · The journal of obstetrics and gynaecology research
Objective To evaluate the impact of bilateral salpingectomy added to hysterectomy performed via different surgical routes on ovarian reserve, ovarian stromal blood flow, and sexual function in premenopausal women. Methods This prospective…
Lee YJ, Clement ND, Asopa V et al. · 2026 · The Journal of arthroplasty
Background The objectives were to evaluate whether the EQ-5D-3L questionnaire demonstrated a ceiling effect after total hip arthroplasty (THA), identify which patients were more likely to reach the ceiling score, and determine whether this…
Boonperm P, Buaboon N, Vatanavilai C et al. · 2026 · Journal of human lactation : official journal of International Lactation Consultant Association
Background Breastfeeding is a key strategy for improving maternal and infant health; however, Thailand continues to fall short of national and international breastfeeding targets. Village Health Volunteers (VHVs) play an essential role in…
Seward M, Puiras E, Crocker CE et al. · 2026 · BMC psychiatry
Background 30% of individuals with schizophrenia do not respond to first line dopamine-blocking antipsychotic medications and meet criteria for treatment resistant schizophrenia (TRS). Elevated glutamate levels in the anterior cingulate…
Sinha R, Sabir M, Tripathi M et al. · 2026 · Indian journal of ophthalmology
Objective To evaluate the role of local oxygen supplementation in accelerated collagen cross-linking (CXL) in human subjects. Method Patients with progressive keratoconus were enrolled and randomized to undergo accelerated CXL in either…
Vasamsetti SR, Guddeti A, Kumar S et al. · 2026 · Nigerian journal of clinical practice
Background Hypothyroidism is a common condition, and thyroid hormones play a key role in metabolism and fat regulation. We examined how levothyroxine affects visceral adipose tissue (VAT) and body composition using dual-energy X-ray…
Kim S, Kim YJ, Yoon YH et al. · 2026 · International journal of retina and vitreous
Purpose This study aimed to investigate the spatial correlation between retinal structure and function in macular telangiectasia type 2 (MacTel) using Compass fundus-tracked microperimetry. Methods Medical records of 54 eyes from 28…
Ting J, Grills N, Sochet AA et al. · 2026 · Pediatric cardiology
Critical congenital heart disease (CCHD) screening using pulse oximetry was mandated by all states between 2011-2018. We sought to evaluate the effect on the age at initial admission to a children's hospital, the hospital length of stay…
Soliman S, Said D, Maqsood S et al. · 2026 · Advances in therapy
Introduction Infectious keratitis can lead to significant ocular morbidity and threaten vision if not treated promptly with antimicrobial therapy. Adjuvant treatment with corneal cross-linking (CXL) can improve visual outcomes in cases of…
Borhany M, Iqbal HT, Abid M et al. · 2026 · Clinical medicine insights. Pediatrics
Background Sickle cell disease (SCD) is characterized by a chronic hypercoagulable state. Hydroxyurea (HU) is known to reduce the frequency of vaso-occlusive events and transfusion requirements in affected individuals. Objective To assess…
Bonnet E, Ikpo D, Kodo M et al. · 2026 · Traffic injury prevention
Objective Road traffic injuries are a leading cause of death among children in Africa, especially in urban areas with inadequate infrastructure. Despite this, few scientifically taught educational initiatives to address this issue at the…
Butler A, Croxford R, Owusu-Bempah A et al. · 2026 · The International journal on drug policy
Background In October 2018, Canada legalized non-medical cannabis possession and use. While a stated objective of legalization was to prevent people from entering the criminal justice system for cannabis possession, we lack evidence about…
Shiraiwa K, Sueshige Y, Tanaka R et al. · 2026 · Preprint
Aims: Lenvatinib (LEN) inhibits organic anion transporting polypeptide 1B1 (OATP1B1) in vitro , raising concerns about potential risk for transporter-mediated drug–drug interactions (DDIs). This study evaluated the in vivo impact of LEN on…
Qian H, Jin H, Li S · 2026 · Clinical biochemistry
Objective To investigate the cause of markedly elevated cardiac troponin I (cTnI) levels that were inconsistent with the clinical presentation in an 18-year-old male patient with bradycardia. Methods Serial dilution analysis, heterophile…
Bellali YA, Jetté S, Delisle M et al. · 2026 · Journal of burn care & research : official publication of the American Burn Association
Paraffin wax is applied to scar tissue for its proposed benefits of increasing skin pliability and relieving pain. However, limited studies have objectively assessed hypertrophic scar (HSc) response. This study examined immediate HSc…