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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19902 results in Negative / Null Result Report · page 595 of 664

Negative / Null Result ReportOpen accessMedicine

Characteristics of atmospheric dustfall fluxes and particle size in an open pit coal mining area and surrounding areas

Yayuan Deng, Hongxuan Wu, Tingning Zhao et al. · 2025 · Scientific Reports

Abstract Atmospheric dustfall is solid air pollutant, which is mainly influenced by local sources, so it has a major impact on the local environment and the health of local residents. The objective of this study was to investigate the distribution characteristics of dustfall fluxes and particle size, and the meteorological factors affected them. Atmospheric dustfall was collected in an open-pit coal mining area and surrounding areas in the arid desert area of Northwest China from March to December 2018. Dustfall fluxes was measured, particle size was measured by using graphical methods and gra

View details →DOI: 10.1038/s41598-025-94161-4
Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system

The role of suction drainage in the management of peri-operative bleeding in Total and Unicomcompartmental knee arthroplasty: a retrospective comparative study

Nicola Manta, Laura Mangiavini, Cristiana Balbino et al. · 2021 · BMC Musculoskeletal Disorders

Abstract Background Suction drainage is commonly applied after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) to reduce hematoma, swelling and to favor surgical wound healing. However, its efficacy remains controversial; thus, the purpose of this study is to evaluate drainage efficiency in the management of postoperative bleeding in TKA and UKA. Methods The cohort comprised 134 clinical records of patients affected by knee osteoarthritis (OA) who underwent either TKA or UKA. All the patients were subdivided into 2 groups: the first one with drainage and the second o

View details →DOI: 10.1186/s12891-021-04868-4
Negative / Null Result ReportOpen accessVeterinary medicine

Exploring the relationship between calcitonin, ionized calcium, and bone turnover in cats with and without naturally occurring hypercalcemia

Evangelia Maniaki, Carmen Pineda, Angie Hibbert et al. · 2024 · Frontiers in Veterinary Science

ObjectivesThis case-control study aimed to evaluate calcitonin response in naturally occurring hypercalcemia in cats and assess the relationships between calcitonin and ionized calcium (iCa) and examine relationships between calcitonin, iCa and bone turnover.MethodsHypercalcemic cats (persistently increased iCa concentration [>1.40 mmol/l]) were identified retrospectively via a medical database search; additional hypercalcemic and normocalcemic cats were recruited prospectively. Data regarding routine biochemical and urine testing, diagnostic imaging and additional blood testing were obtained.

View details →DOI: 10.3389/fvets.2024.1399942
Negative / Null Result ReportOpen accessMedicine

Effect of baseline characteristics on mortality in the SURVIVE trial on the effect of levosimendan vs dobutamine in acute heart failure: Sub-analysis of the Finnish patients.

M. Kivikko, P. Pollesello, Tuukka Tarvasmäki et al. · 2016 · International Journal of Cardiology

BACKGROUND In the SURVIVE trial, including 1327 acute heart failure patients, no statistically significant difference between levosimendan and dobutamine in the 180-day all-cause mortality was seen. Country-specific differences in outcome…

View details →DOI: 10.1016/j.ijcard.2016.04.064
Negative / Null Result ReportOpen accessMedicine

Grading angiogenesis in oral squamous cell carcinoma: a histomorphometric study.

V. Wadhwan, Preeti Sharma, Chitrapriya Saxena et al. · 2015 · Indian Journal of Dental Research

CONTEXT Like normal tissues, tumors require an adequate supply of oxygen, metabolites and an effective way to remove waste products. This is achieved by angiogenesis, which is defined as the process by which new blood vessels are produced…

View details →DOI: 10.4103/0970-9290.156792
Negative / Null Result ReportOpen access

Microscale Dynamics of Larval Fish Assemblages in the Straits of Malacca Nearshore Coincided with Lunar Phases

Ali Md. Yeakub, Fatimah Md. Yusoff, Natrah Fatin Mohd. Ikhsan et al. · 2023 · Pertanika Journal of Tropical Agricultural Science

Marine fish larvae are an integral part of the marine environment because their abundance can become an ecological indicator. The abundance is dependent on the environmental variations that include but are not limited to lunar phases and…

View details →DOI: 10.47836/pjtas.46.4.18
Negative / Null Result ReportOpen accessMedicine

Cardiac Effects of in utero Exposure to Antiretroviral Therapy in HIV-Uninfected Children Born to HIV-Infected Mothers

S. Lipshultz, Paige L. Williams, B. Zeldow et al. · 2015 · AIDS (London)

Objectives:We evaluated the potential cardiac effects of in-utero exposures to antiretroviral drugs in HIV-exposed but uninfected (HEU) children. Design and methods:We compared echocardiographic parameters of left ventricular function…

View details →DOI: 10.1097/qad.0000000000000499
Negative / Null Result ReportMedicine

Reappraisal of Electrocardiographic Criteria for Localization of Idiopathic Outflow Region Ventricular Arrhythmias.

James K. Gabriels, M. Abdelrahman, Lakshmi Nambiar et al. · 2021 · Heart Rhythm

BACKGROUND Electrocardiographic (ECG) criteria have been proposed to localize the site of origin (SOO) of outflow region ventricular arrhythmias (VAs). Many factors influence the QRS morphology of VAs and may limit the accuracy of these…

View details →DOI: 10.1016/j.hrthm.2021.08.003
Negative / Null Result ReportMedicine

Trial of Electronic Medical Record Integrated Next-Generation Sequencing Ordering in Veterans Affairs Cancer Care

J. Stoeckle, S. Poland, H. Maynard et al. · 2024 · JCO Precision Oncology

PURPOSE Previous studies document underuse of next-generation sequencing (NGS). We examined the impact to oncology care for veterans of incorporating NGS ordering into the Veterans Affairs (VA) electronic medical record (EMR) at two New…

View details →DOI: 10.1200/po.23.00463
Negative / Null Result ReportOpen accessMedicine

Successful weight loss maintenance in relation to method of weight loss

Angela Marinilli Pinto, A. A. Gorin, Hollie A Raynor et al. · 2008 · Obesity

This study examined the relation between method of weight loss and long‐term maintenance among successful weight losers enrolled in a weight‐loss maintenance trial. Participants were 186 adults (mean age = 51.6 ± 10.7 years, mean BMI =…

View details →DOI: 10.1038/oby.2008.364
Negative / Null Result ReportMedicine

Comparative Pathologic Analysis of Breast Cancers Classified as HER2/neu-Amplified by FISH Using a Standard HER2/CEP17 Dual Probe and an Alternative Chromosome 17 Control Probe

Somaye Y. Zare, Leo I. Lin, Abrar Alghamdi et al. · 2018 · American Journal of Surgical Pathology

At our institution, breast cancer cases that generate an equivocal HER2/neu (HER2) result by fluorescence in situ hybridization (FISH) using the dual HER2/chromosome enumeration probe (CEP17) are reflexed to an assay that utilizes an…

View details →DOI: 10.1097/pas.0000000000001106
Negative / Null Result ReportOpen accessMedicine

Sex differences in uric acid and NT-pro BNP assessments during coronary severity

Guofeng Guo, Zhaoqi Huang, Shixiang Wang et al. · 2020 · Medicine

Abstract To investigate the correlation between uric acid (UA) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and coronary artery severity in acute coronary syndrome patients of different sexes. A total of 134 patients…

View details →DOI: 10.1097/md.0000000000019653
Negative / Null Result ReportOpen access

The link between personality dimensions, impulsivity, decision and coping style, and suicide attempts in affective patients.

J. Pawlak, K. Bilska, M. Skibińska et al. · 2024 · European psychiatry

Introduction Introduction: Affective patients, especially depressive, have an increased risk of suicidal behavior. Identifying individuals at increased risk remains a challenge. Among the correlates that may be crucial, the impact of…

View details →DOI: 10.1192/j.eurpsy.2024.517
Negative / Null Result ReportOpen access

Comparison of the effects of direct laryngoscopic and fiberoptic oral endotracheal intubation on the intraocular pressures of non-ophthalmic patients: A prospective, randomised, clinical trial

S. M., A. Ozkan, S. Akbaş et al. · 2022 · Annals of Medical Research

Aim: In this prospective, randomised, clinical study; we aimed to compare the effects of endotracheal intubation (ETI) via direct laryngoscope (DLS) and fiberoptic bronchoscope (FOB) on intraocular pressure (IOP) and haemodynamic data of…

View details →DOI: 10.5455/annalsmedres.2021.12.669
Negative / Null Result ReportOpen accessMedicine

Physical Activity and Sedentary Behavior in Children With Congenital Heart Disease

C. Voss, S. Duncombe, Paige H. Dean et al. · 2017 · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease

Background Children with congenital heart disease (CHD) are thought to have low levels of physical activity (PA), but few studies have used objective measures of PA in this population. Methods and Results We recruited patients with mild,…

View details →DOI: 10.1161/jaha.116.004665
Negative / Null Result ReportMedicine

Study on Normal Laryngeal Electromyography of Thyroarytenoid Muscle, Cricothyroid Muscle, and Posterior Cricoarytenoid Muscle

Xinlin Xu, Pan Yang, P. Zhuang et al. · 2018 · Annals of Otology, Rhinology and Laryngology

Objective: The aim of this study was to investigate the physiological activity of intrinsic laryngeal muscle under different functional states of larynx by measuring the normal laryngeal electromyography parameters. Methods: Laryngeal…

View details →DOI: 10.1177/0003489418796525
Negative / Null Result ReportOpen accessMedicine

GlideScope® versus C-MAC®(D) videolaryngoscope versus Macintosh laryngoscope for double lumen endotracheal intubation in patients with predicted normal airways: a randomized, controlled, prospective trial

P. Huang, Renlong Zhou, Zhi-juan Lu et al. · 2020 · BMC Anesthesiology

Background The double lumen endotracheal tube (DLT) is the most widely-used device for single lung ventilation in current thoracic anesthesia practice. In recent years, the routine application of the videolaryngoscope for single lumen…

View details →DOI: 10.1186/s12871-020-01012-y
Negative / Null Result ReportOpen accessMedicine

Discrepancies between leg-to-leg bioelectrical Impedance analysis and computerized tomography in abdominal visceral fat measurement

Hsueh-Kuan Lu, Yu-Ywan Chen, Chin-Jung Yeh et al. · 2017 · Scientific Reports

The aim of this study was to evaluate leg-to-leg bioelectrical impedance analysis (LBIA) using a four-contact electrode system for measuring abdominal visceral fat area (VFA). The present study recruited 381 (240 male and 141 female)…

View details →DOI: 10.1038/s41598-017-08991-y
Negative / Null Result ReportOpen accessMedicine

Comparison of corneal changes after phacoemulsification using BSS Plus versus Lactated Ringer's irrigating solution: a prospective randomised trial

D. R. Lucena, M. S. Ribeiro, A. Messias et al. · 2010 · British Journal of Ophthalmology

Background/aims To compare two intraocular irrigating solutions, Balanced Salt Solution Plus (BSS Plus) versus Lactated Ringer's (Ringer), for the preservation of corneal integrity after phacoemulsification. Methods 110 patients undergoing…

View details →DOI: 10.1136/bjo.2009.172502
Negative / Null Result ReportMedicine

Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)

D. Aparicio-López, J. Ramia, C. Villodre et al. · 2025 · Journal of Clinical Medicine

Background/Objectives: Like many other countries, the management of pancreatic cancer in Spain has developed in a fragmented manner. This study analyzes clinical outcomes related to patient volume at different centers after left…

View details →DOI: 10.3390/jcm14176013
Negative / Null Result ReportOpen accessMedicine

The Effect of Two Calcium Silicate Materials on the Fracture Strength of Simulated Immature Teeth during Regenerative Endodontic Treatment

H. Edrees, A. Y. Siddiqui, M. M. Almousa et al. · 2021 · Journal of Evolution of Medical and Dental Sciences

BACKGROUND Necrotic immature permanent teeth undergoing Regenerative Endodontic Treatment (RET) are subjected to functional forces that might lead to their fracture before achieving apical closure. This study compared the fracture strength…

View details →DOI: 10.14260/jemds/2021/552
Negative / Null Result ReportMedicine

A Half-Century Review of Male and Female Resident Outcomes in Oral and Maxillofacial Surgery: A Single-Institution Report.

Susan Keefe, Carrie Baldwin, Elda Fisher et al. · 2025 · Journal of oral and maxillofacial surgery

BACKGROUND Limited comprehensive historical data exist comparing male and female residents in oral and maxillofacial surgery (OMS) residency programs. This gap underscores the need to examine sex-based differences to guide equitable…

View details →DOI: 10.1016/j.joms.2025.03.011
Negative / Null Result ReportOpen access

Effectiveness of Mechanical Lumbar Traction Positional Variations in Patients with Low Back Pain

G. Murugan, Sheeba Sharon R, A. K. Krishna Kumar · 2023 · International Journal of Health Sciences and Research

BACKGROUND: Low back pain (LBP) is one of the most common causes of disability among the general population. Lumbar traction is an application of distraction force to produce a separation of the joint and elongate the soft tissues.…

View details →DOI: 10.52403/ijhsr.20230217
Negative / Null Result ReportOpen access

Entry Requirements as Predictors of the Academic Performance of Postgraduate Students in Universities in Zimbabwe

Norman Rudhumbu, Patience Kelebogile Mudau · 2022 · International Journal of Learning, Teaching and Educational Research

One of the major strategies that universities use to ensure quality in education is the use of entry requirements as a screening procedure to ensure that only those considered to be the ‘best’ students are admitted. Whether these so-called…

View details →DOI: 10.26803/ijlter.21.2.6
Negative / Null Result ReportOpen accessMedicine

Effectiveness of nano-calcium phosphate paste on sensitivity during and after bleaching: a randomized clinical trial.

A. Loguércio, L. Tay, D. R. Herrera et al. · 2015 · Brazilian Oral Research

The study aimed to evaluate the effectiveness of in-office bleaching and associated tooth sensitivity on application of nano-calcium phosphate paste as desensitizing agent. Bleaching was performed with 35% hydrogen peroxide gel in 40…

View details →DOI: 10.1590/1807-3107bor-2015.vol29.0099
Negative / Null Result ReportMedicine

The Effect of the Lateral First Metatarsal Head Shape on Hallux Valgus in Forced Turnout in Pre-Pointe Female Ballet Dancers: A Pilot Study.

Paul H Doan, David M Handojo, Shivani Parihar et al. · 2024 · Journal of the American Podiatric Medical Association (Print)

BACKGROUND A rounded lateral first metatarsal head shape is associated with higher rates of hallux abducto valgus recurrence following corrective surgery; however, the effect of the lateral first metatarsal head shape on the hallux…

View details →DOI: 10.7547/21-129