Negative / Null Result ReportMedicine
Akbas F, Baykan O, Avcikurt AS et al. · 2026 · BMC psychiatry
Background Major depressive disorder (MDD) has been increasingly associated with low-grade inflammation, with neutrophils playing a central role. Calprotectin is a mainly neutrophil-derived inflammatory mediator. We investigated whether…
View details →DOI: 10.1186/s12888-026-08161-3 Negative / Null Result ReportMedicine
Li M, Jiang C, Wang R et al. · 2026 · Clinical rehabilitation
DesignPragmatic, two-arm, parallel-group, superiority randomised controlled trial with assessor-blinding and statistician-blinding.SettingSingle orthopaedic centre in Shanghai, China.ParticipantsOne hundred and eighty adults (aged 18-50…
View details →DOI: 10.1177/02692155261450149 Negative / Null Result ReportMedicine
Anteby M, Wertheimer KO, Dominsky O et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Objective To compare maternal and neonatal outcomes between women with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome with and without associated hypertension. Methods This was a retrospective cohort study at a…
View details →DOI: 10.1002/ijgo.71073 Negative / Null Result ReportMedicine
Otowa Y, Matsuda T, Ando M et al. · 2026 · Surgery today
Background The benefit of neoadjuvant chemoradiotherapy (NACRT) for elderly patients with locally advanced rectal cancer (LARC) remains unclear because these patients are often excluded from trials. We evaluated the safety and oncologic…
View details →DOI: 10.1007/s00595-026-03306-z Negative / Null Result ReportMedicine
Hu X, Murakami G, Hasegawa H · 2026 · International journal of sports physiology and performance
Purpose This study evaluated the practical feasibility of the CORE sensor for noninvasive tracking of changes in estimated core body temperature (Est-Tcore) during simulated beach volleyball match-play in the heat and examined the effects…
View details →DOI: 10.1123/ijspp.2025-0588 Negative / Null Result ReportMedicine
Cao H, Zhou Y, Gu N et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Objectives This study evaluates oral azithromycin's effectiveness in reducing intrapartum and puerperal infection rates in term pregnant women undergoing labor induction to guide antibiotic prophylaxis. Methods This single-center…
View details →DOI: 10.1002/ijgo.71083 Negative / Null Result ReportMedicine
Peters S, Tan DSW, Gerber DE et al. · 2026 · Nature cancer
Over 50% of persons with unresectable stage III non-small cell lung cancer (NSCLC) treated with standard-of-care concurrent chemoradiotherapy (CCRT) and durvalumab consolidation progress or die within 18 months. Here adults with untreated,…
View details →DOI: 10.1038/s43018-026-01161-y Negative / Null Result ReportMedicine
Schulz JV, Doerflinger JT, Behm C et al. · 2026 · Health psychology : official journal of the Division of Health Psychology, American Psychological Association
Objective This study compares three models of parental human papillomavirus (HPV) vaccination intentions across United States, United Kingdom, and Germany: A model based on the theory of planned behavior (TPB), a model incorporating…
View details →DOI: 10.1037/hea0001596 Negative / Null Result ReportOpen accessMedicine
Yang Y, He Y, Lin B et al. · 2026 · Health care science
Background The aim of this study was to investigate the clinical value of combined detection of preoperative serum calcitonin (Ctn) and carcinoembryonic antigen (CEA) for diagnosing medullary thyroid carcinoma (MTC), as well as predicting…
View details →DOI: 10.1002/hcs2.70074 Negative / Null Result ReportMedicine
Drago E, Lavarello C, Alongi A et al. · 2026 · Clinical and experimental rheumatology
Objectives Development and psychometric evaluation of a disease-specific, paediatric-targeted multidimensional questionnaire for the assessment of juvenile fibromyalgia syndrome (JFS) in routine clinical practice. Methods The Juvenile…
View details →DOI: 10.55563/clinexprheumatol/0v4aqh Negative / Null Result ReportMedicine
Genuth G, Stavrou P, Brown C et al. · 2026 · Foot & ankle international
Background Acute lateral ankle sprains are among the most common musculoskeletal injuries, accounting for up to 20% of all sports-related injuries and a leading cause of time lost from athletic participation. Although most cases respond to…
View details →DOI: 10.1177/10711007261422252 Negative / Null Result Report
Hebisch J, Van Puyenbroeck P, Schwabe L et al. · 2025 · Preprint
A bstract Brainstem arousal systems including the locus coeruleus noradrenaline system, respond transiently to behaviorally relevant events. Locus coeruleus activity also drives dilations of the pupil, which are often observed during…
View details →DOI: 10.64898/2025.12.23.696068 Negative / Null Result ReportMedicine
Dertsiz Kozan B, Utlu B · 2026 · International ophthalmology
Purpose To investigate the effects of Mitomycin-C (MMC) use and duration of application on surgical outcomes in patients who underwent 3 snip punctoplasty for epiphora. Material and methods Demographic characteristics, follow-up period,…
View details →DOI: 10.1007/s10792-026-03970-7 Negative / Null Result Report
Shi Z, Chen X, Chun Y et al. · 2026 · Preprint
Abstract Objective To evaluate the efficacy, safety, and prognostic factors of chimeric antigen receptor-T cell (CAR-T) therapy in patients with relapsed/refractory ileocecal lymphoma and provide evidence for salvage therapy. Methods This…
View details →DOI: 10.21203/rs.3.rs-8776621/v1 Negative / Null Result ReportMedicine
Pérez-Fernández N, Arbizu L · 2026 · Journal of clinical medicine
Background : Differentiating Ménière's disease (MD) from vestibular migraine (VM) remains difficult because current diagnostic frameworks are predominantly clinical and incorporate pure-tone thresholds, risking incorporation bias. We asked…
View details →DOI: 10.3390/jcm15051908 Negative / Null Result ReportMedicine
Sabharwal P, Kaur N, Kaur R et al. · 2026 · Journal of ultrasound
Objectives To determine the incremental diagnostic value of multiparametric quantitative ultrasound-integrating B-mode, Color Doppler, Strain, and Shear Wave Elastography (SWE)-in differentiating benign and malignant breast lesions, using…
View details →DOI: 10.1007/s40477-026-01116-0 Negative / Null Result ReportMedicine
Wang L, Pulgrossi RC, Anderson J et al. · 2026 · The journal of applied laboratory medicine
Background Acute graft-versus-host disease (aGVHD) is a common complication of allogenic hematopoietic cell transplantation (HCT). The aGVHD presymptomatic algorithm is comprised of 2 serum biomarkers, suppression of tumorigenicity 2 and…
View details →DOI: 10.1093/jalm/jfaf193 Negative / Null Result ReportMedicine
Delaye-Martínez MA, Aguilar-Rodea BP, Cardona-Ortiz AF et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Purpose Nebulized colistin has shown promise in treating ventilator-associated pneumonia (VAP) due to carbapenem-resistant strains; evidence in burn patients is limited. This study evaluated the efficacy of nebulized colistin as an adjunct…
View details →DOI: 10.1007/s10096-026-05550-0 Negative / Null Result ReportMedicine
Rusa AM, Schmidlin PR, Sarkar P et al. · 2026 · Swiss dental journal
Large language models (LLMs) are increasingly used in clinical and educational settings. However, there is a paucity of data on LLMs' performance in specialized dental domains. This study assessed the performance of four LLMs, including…
View details →DOI: 10.61872/sdj-2025-04-04 Negative / Null Result ReportMedicine
Zou Q, Huang Q, Li J et al. · 2026 · International urology and nephrology
Background The optimal treatment strategy for androgen receptor pathway inhibitor (ARPI)-pretreated and chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) remains unclear. Chemotherapy has limited efficacy as a…
View details →DOI: 10.1007/s11255-026-05064-w Negative / Null Result Report
Oscorbin IP, Smertina MA, Kunova MS et al. · 2025 · Preprint
The metal-binding periplasmic protein CusF has been proposed as a bifunctional tag enhancing solubility of recombinant proteins and enabling purification using Cu affinity chromatography. However, evidence for its performance remains…
View details →DOI: 10.20944/preprints202512.0908.v1 Negative / Null Result ReportMedicine
van Boven M, Bennis F, Onland W et al. · 2025 · IEEE journal of biomedical and health informatics
Machine learning models predicting neurodevelopmental outcome in preterm infants have great potential, but have often relied on inaccessible brain magnetic resonance imaging measurements. This study aimed to build models using readily…
View details →DOI: 10.1109/jbhi.2025.3559793 Negative / Null Result ReportMedicine
Hoyle JD Jr, Ekblad G, Dunwoody S et al. · 2026 · Prehospital emergency care
Objectives We sought to decrease pediatric prehospital dosing errors by implementing a bundled drug dosing safety system (DDSS). Multiple studies have demonstrated that pediatric prehospital drug-dosing errors occur at rates of > 30% for…
View details →DOI: 10.1080/10903127.2025.2609784 Negative / Null Result ReportMedicine
Ivanov AL, Reshetnyak EI, Sukacheva SA · 2026 · Stomatologiia
Objective To evaluate mandibular donor site healing after cortical bone graft harvesting in cleft patients, comparing outcomes of osteotomies performed with rotary burs and piezosurgery. Material and methods Fifty-three patients (64 bone…
View details →DOI: 10.17116/stomat202610501137 Negative / Null Result ReportMedicine
Marshall PW, Benatar JR, O'Halloran P et al. · 2026 · Heart, lung & circulation
Aim Suboptimal enrolment and engagement in cardiac rehabilitation remains a persistent issue worldwide. This study evaluated the impact of a nurse-specialist-delivered motivational interviewing (MI) and cognitive behavioural therapy (CBT)…
View details →DOI: 10.1016/j.hlc.2025.10.006 Negative / Null Result Report
Sponholtz MR, Ma D, Byrne PO et al. · 2026 · Preprint
ABSTRACT Herpes simplex virus type 2 (HSV-2) causes genital herpes through latent infection and periodic reactivation. Although antivirals alleviate symptoms, no prophylactic or therapeutic vaccines have been licensed. Glycoprotein B (gB)…
View details →DOI: 10.64898/2026.01.26.701809 Negative / Null Result ReportMedicine
Hagger V, Hendrieckx C, Cotterill A et al. · 2026 · Diabetic medicine : a journal of the British Diabetic Association
Aim To examine changes in psychological and clinical outcomes among adolescents and parents after structured type 1 diabetes education delivered in routine care. Methods Teens Empowered to Actively Manage Type 1 Diabetes (TEAM T1) is a…
View details →DOI: 10.1111/dme.70244 Negative / Null Result ReportMedicine
Nakatsuka M, Pelletier-Roy R, Paturi A et al. · 2026 · Spine
Study design Retrospective cohort study of patients undergoing single-level L5-S1 anterior or transforaminal lumbar interbody fusion between 2012 and 2024 at a single academic institution, with preoperative and one-year postoperative…
View details →DOI: 10.1097/brs.0000000000005643 Negative / Null Result ReportOpen accessMedicine
Perrier Q, Lablanche S, Moro C · 2026 · Lasers in medical science
Photobiomodulation (PBM) has been shown to protect pancreatic islets under inflammatory or metabolic stress, but its effects during hypoxia-reperfusion remain unclear. We evaluated PBM applied as preconditioning or during…
View details →DOI: 10.1007/s10103-026-04867-8 Negative / Null Result ReportMedicine
Li JL, Wu JH, Zhao X et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
BACKGROUND: The role of prophylactic cavotricuspid isthmus (CTI) ablation remains controversial in atrial fibrillation (AF) patients without atrial flutter (AFL). Given the strong association between AF, AFL, and age, this study aimed to…
View details →DOI: 10.1007/s10840-026-02305-x 