Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Yulu Miao, Bin Wang, Jing Hu et al. · 2022 · Frontiers in Pharmacology
Lung infection is a common complication induced by stroke and seriously affects the prognosis and life quality of patients. However, effective therapeutic strategies are still lacking. In the present study, the herb formula GCis was confirmed to prevent pulmonary infection induced by intracerebral hemorrhage (ICH). The animal model of lung infection induced by ICH, GCis (Ginseng Radix et Rhizoma, Aconiti Lateralis Radix Praeparata, and Cistanches Herba) was orally administrated every day for 7 days. Lung microbial biomass and pathological results showed that the GCis formula pretreatment signi
View details →DOI: 10.3389/fphar.2022.888684 Negative / Null Result ReportOpen accessAgriculture
Noor Fitriya Mirta Liana Tata, Syaiful Anwar, Florentina Kusmiyati · 2022 · Jurnal Ilmiah Pertanian
Red chili (Capsicum annum L.) is a vegetable that has high economic value. However, red chili production has decreased because of seed deterioration, such as expired seeds. Seed invigoration attempts to maintain seed germination ability when it has deteriorated. Extracts of onion and banana weevil can be used for invigoration. The research aimed to know the effect of various natural hormones, soaking time, and interaction of the two treatments of expired red chili seeds on germination, growth, and production. The research used a factorial, completely randomized design (CRD), which consisted of
View details →DOI: 10.31849/jip.v19i3.10569 Negative / Null Result ReportOpen accessMedicine (General)
Nahla Tharwat Moussa Ahmed, Hany Ezzat Obaya, Azza Abd Elaziz Abd Elhadi et al. · 2025 · Вестник восстановительной медицины
INTRODUCTION. The double chin is an excessive accumulation of fat in the pre- and post-platysma that can manifest in various forms and sizes. Thin individuals might manifest a double chin, similar to those who are afflicted by obesity. It may result in a reduction in the definition of the mandible and give the perception of obesity or aging. AIM. To evaluate any effect of High-Intensity Focused Ultrasound (HIFU) on sleep quality measures in obese women with a double chin. MATERIALS AND METHODS. Typically, 60 women aged 35–50 years were selected from AL Qasr-Alaini Hospital and were equally div
View details →DOI: 10.38025/2078-1962-2025-24-1-47-54 Negative / Null Result ReportOpen accessMedicine
Anna Keodara, Lukas Jeker, Lars Straub et al. · 2024 · Scientific Reports
Abstract Bees are often exposed to pesticides affecting physiological functions and molecular mechanisms. Studies showed a potential link between altered expression of energy metabolism related transcripts and increased homing flight time of foragers exposed to pesticides. In this study, we investigated the effects of thiamethoxam and pyraclostrobin on longevity, flight behavior, and expression of transcripts involved in endocrine regulation (hbg-3, buffy, vitellogenin) and energy metabolism (cox5a, cox5b, cox17) using radio frequency identification (RFID) technology and quantitative polymeras
View details →DOI: 10.1038/s41598-024-73235-9 Negative / Null Result ReportOpen accessMedicine
Jerzy A Zoladz, Joanna Majerczak, Bruno Grassi et al. · 2016 · PLoS ONE
In this study we have examined the effect of prolonged endurance training program on the pulmonary oxygen uptake (V'O2) kinetics during heavy-intensity cycling-exercise and its impact on maximal cycling and running performance. Twelve healthy, physically active men (mean±SD: age 22.33±1.44 years, V'O2peak 3198±458 mL ∙ min-1) performed an endurance training composed mainly of moderate-intensity cycling, lasting 20 weeks. Training resulted in a decrease (by ~5%, P = 0.027) in V'O2 during prior low-intensity exercise (20 W) and in shortening of τp of the V'O2 on-kinetics (30.1±5.9 s vs. 25.4±1.5
View details →DOI: 10.1371/journal.pone.0154135 Negative / Null Result ReportOpen accessChemistry
Maria A. Rezvova, Pavel A. Nikishau, Miraslau I. Makarevich et al. · 2022 · Nanomaterials
Nanocomposites based on poly(styrene- block -isobutylene- block -styrene) (SIBS) and single-walled carbon nanotubes (CNTs) were prepared and characterized in terms of tensile strength as well as bio- and hemocompatibility. It was shown that modification of CNTs using dodecylamine (DDA), featured by a long non-polar alkane chain, provided much better dispersion of nanotubes in SIBS as compared to unmodified CNTs. As a result of such modification, the tensile strength of the nanocomposite based on SIBS with low molecular weight (M n = 40,000 g mol –1 ) containing 4% of functionalized CNTs was in
View details →DOI: 10.3390/nano12050733 Negative / Null Result ReportOpen accessForestry
Irwan Mahakam Lesmono Aji, Raden Sutriono, Arna Diansyah · 2020 · Jurnal Belantara
This study aims to find out the effect of submersion by using 1% acetic acid, 100% palm juice, and 100% coconut water to break the dormancy of palm seeds at different maturity levels. The research was conducted in the Green House of Forestry Study Program, University of Mataram, using the experimental method with Complet Random Design (CRD) three factors. The first factor is the maturity level consists of 3 levels, the second factor is the submersion liquid substance consist of 3 levels, and the third factor is the period of submersion consist of 4 levels.The results of this study indicate tha
Negative / Null Result ReportOpen accessForestry
P. Formánek, V. Vránová · 2003 · Journal of Forest Science
The effect of thinning of young spruce stands by 500 trees/ha on biological activity in the soil profile was studied in the mountainous area of the Moravian-Silesian Beskids. The biological activity of soil was determined under optimal laboratory conditions by tests of soil respiration, catalase activity and intensity of cellulose decomposition. No statistically significant differences were found between the individual biological tests when the two experimental stands were compared (P-level 0.05). All biological activities within each stand were correlated, and significant correlations were fo
View details →DOI: 10.17221/4795-jfs Negative / Null Result ReportOpen accessEnvironmental sciences
Mohamed Rashed, Asmaa Khodari · 2022 · Aswan University Journal of Environmental Studies
TiO2 was synthesized from titanium tetraisopropoxide in the presence of H2O and H2O2 to form TiO2(H2O) and TiO2(H2O2) respectively. Thermo gravimetric analysis (TGA) was utilized to investigate the thermal stability and select proper calcination temperatures of the solid powders used to prepare the oxides. Accordingly, TiO2 was obtained by calcination at 550 and 750°C. These oxides were characterized by TEM, XRD, FTIR, XRF and UV-Vis spectroscopy. Results showed that TiO2(H2O2) is more thermally stable than TiO2(H2O) and its nanoparticles are smaller. TiO2(H2O2)(550) was doped with palladium t
View details →DOI: 10.21608/aujes.2022.145415.1076 Negative / Null Result ReportOpen accessAgriculture (General)
Stanisław Sienkiewicz, Sławomir Krzebietke, Jadwiga Wierzbowska et al. · 2004 · Agronomy Science
The objective of the study was to determine modifications in the content of available nutrients, organic carbon, total nitrogen and mineral forms of nitrogen occurring under the effect of long-term mineral and mineral-organic fertilization. The experiments were carried out on two fields between 1998 and 2001. They covered the fourth rotation of a long-term field trial established in 1986. On grey-brown podzolic soil formed from loamy clay, the following crops were grown in rotation: sugar beet, spring barley, maize and spring wheat. The soil analyses carried out prior to the tests showed that
Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Tanja Elnaz Hassanzadeh, Tanja Elnaz Hassanzadeh, Carina Hohmann et al. · 2024 · Frontiers in Pharmacology
Polypharmacy is common among patients with antithrombotic medication, giving rise to concerns about Drug-Related Problems (DRPs). Therefore, these patients would benefit from a Medication Review (MR) along with pharmacist counselling to reduce the risks accompanying polymedication. This prospective study presents a concept for MRs that are applicable in German community pharmacies and can efficiently support pharmacist counselling and improve the safety of drug therapy. As this is a major challenge in everyday pharmacy practice, we used a Decision Support System (DSS) to evaluate its ability t
View details →DOI: 10.3389/fphar.2024.1194201 Negative / Null Result ReportOpen accessDiseases of the respiratory system
Joshua Trivlidis, Noof Aloufi, Fatmah Al-Habeeb et al. · 2021 · Respiratory Research
Abstract Background Pulmonary fibrosis is thought to be driven by recurrent alveolar epithelial injury which leads to the differentiation of fibroblasts into α-smooth muscle actin (α-SMA)-expressing myofibroblasts and subsequent deposition of extracellular matrix (ECM). Transforming growth factor beta-1 (TGF-β1) plays a key role in fibroblast differentiation, which we have recently shown involves human antigen R (HuR). HuR is an RNA binding protein that also increases the translation of hypoxia inducible factor (HIF-1α) mRNA, a transcription factor critical for inducing a metabolic shift from
View details →DOI: 10.1186/s12931-021-01916-4 Negative / Null Result ReportOpen accessSports medicine
John T. Strony MD, Yazdan Raji MD, Jason G. Ina MD et al. · 2023 · Orthopaedic Journal of Sports Medicine
Background: On August 31, 2017, Ohio passed legislation that regulates how opioids can be prescribed postoperatively. Studies have shown that such legislation is successful in reducing the morphine milligram equivalents (MMEs) prescribed after certain orthopaedic procedures. Purpose: (1) To determine if the opioid prescription–limiting legislation in Ohio reduced the cumulative MMEs prescribed after hip arthroscopy without significantly affecting the rates of emergency department (ED) visits, hospital readmissions, and reoperations within 90 days postoperatively, and (2) to assess risk factors
View details →DOI: 10.1177/23259671231162340 Negative / Null Result ReportOpen accessPublic aspects of medicine
Tatin Wahyanto, Stefanus Supriyanto, Nyoman Anita Damayanti et al. · 2020 · Journal of Public Health Research
Background: The high turnover rate in the healthcare industry needs serious attention since it influences hospital service quality. So, there is a need to develop a new framework known as people equity, that can be used to manage intangible assets and reduce employees’ intention to leave. The purpose of this study therefore was to develop a model of people equity as a strategy for enhancing employees’ intention to stay. Design and methods: An analytical cross-sectional design was used to measure the associations between variables. 154 respondents were selected from stratified random sampling t
View details →DOI: 10.4081/jphr.2020.1843 Negative / Null Result ReportOpen accessMedicine
Hassan Nakisa, Fatemeh Ayoobi, Vahid Ehsani et al. · 2015 · مجله دانشگاه علوم پزشکی بیرجند
Background and Aim: Oxidative stresses are involved in neuronal degeneration of substantia nigra and thereby induction of Parkinson's disease. It is reported that Foeniculum Vulgare L. can affect lactating and modulating dopaminergic system activity and antioxidant activity as well. In the present study, the effects of methanolic extract of Foeniculum Vulgare seeds on a Parkinson’s disease model induced by ICV injection of 6-hydroxydopamin (6-OHDA) in female rats were investigated. Materials and Methods: In this experimental study, 60 female rats were randomly divided into 6 equal groups inclu
Negative / Null Result ReportOpen accessEducation
Candra Mustika, Rahma Nurjanah, Sylvia Kartika Wulan · 2023 · JPPI (Jurnal Penelitian Pendidikan Indonesia)
Poverty and inequality are the main problems faced by a country including Indonesia. The purpose of this study was to determine and analyze the comparison of poverty and inequality levels on the islands of Sumatra and Java and to analyze the effect of the human development index (HDI), gross regional domestic product (GRDP), the level of open unemployment (TPT) and total population on poverty and income distribution inequality in Sumatra and Java. The research method used is quantitative descriptive with multiple regression analysis using panel data with provincial research objects on the isla
View details →DOI: 10.29210/020231686 Negative / Null Result ReportOpen accessAnimal culture
Stefanie Alvarenga Santos, José Maurício de Souza Campos, Sebastião de Campos Valadares Filho et al. · 2010 · Revista Brasileira de Zootecnia
Foram avaliadas dietas com silagem de milho e concentrado à base de farelo de soja ou farelo de algodão para fêmeas leiteiras. Quatro dietas experimentais foram constituídas da combinação de dois níveis de concentrado (1 ou 2 kg) e duas fontes proteicas (farelo de soja ou farelo de algodão). Observou-se efeito da interação nível de concentrado fonte proteica no consumo de matéria seca (MS), fibra em detergente neutro (FDN) e no consumo de nutrientes digestíveis totais (NDT). A quantidade de concentrado influenciou os consumos de proteína bruta (PB), FDN, extrato etéreo (EE), carboidratos nãofi
View details →DOI: 10.1590/s1516-35982010000300025 Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Qiwei Li, Jie Zhou · 2025 · Journal of Medical Internet Research
BackgroundNews portrayals of physicians, especially in China, often depict them as vulnerable—overworked, with inadequate compensation, or as victims of violence. These portrayals may send mixed signals to the public, yet their impact remains underexplored. Understanding their impact is essential for informing media strategies and improving physician-patient relationships. ObjectiveThis study investigated how portrayals of physicians as vulnerable influence public evaluations of their competence, warmth, morality, and overall trust and considered the moderating effects of involvement (ie, hosp
View details →DOI: 10.2196/67947 Negative / Null Result ReportOpen accessPlant culture
Niloofar Montazemi, Akram Halajnia, reza khorassani et al. · 2023 · بوم شناسی کشاورزی
Introduction Organic fertilizer tea is a treated solution of organic fertilizers that contains a variety of organic compounds, nutrients and a wide range of microorganisms and their metabolites. In recent years production and use of organic tea as a liquid biological fertilizer or biological pesticides is expanding towards sustainable agriculture. There are many benefits to using tea compost, including providing the nutrients for plant which can reduce the use of chemical fertilizers. A variety of organic compounds can be used to make tea. In the preparation of aerobic organic tea, except for
View details →DOI: 10.22067/agry.2021.72319.1065 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Ingemansson Sandra, Wickenberg Jennie, Hlebowicz Joanna · 2010 · Nutrition Journal
Abstract Background Previous animal studies have shown that Curcuma (C.) longa lowers plasma glucose. C. longa may thus be a promising ingredient in functional foods aimed at preventing type 2 diabetes. The purpose of the study is to study the effect of C. longa on postprandial plasma glucose, insulin levels and glycemic index (GI) in healthy subjects. Methods Fourteen healthy subjects were assessed in a crossover trial. A standard 75 g oral glucose tolerance test (OGTT) was administered together with capsules containing a placebo or C. longa . Finger-prick capillary and venous blood samples w
View details →DOI: 10.1186/1475-2891-9-43 Negative / Null Result ReportOpen accessEconomics as a science
Endang Rostiana, Yusup Fatah Hillah · 2016 · Jurnal Ekonomi Pembangunan: Kajian Masalah Ekonomi dan Pembangunan
This study attempted to identify internal condition of the farmers who sold their paddy field and analyze the effects of age, education level, number of family members, field productivity, location, and production cost to the total area of paddy field sold. This study used quantitative descriptive method. This research found that age, education level, number of family members, and location of the land had positive relation to the total area of paddy field sold. On the other hand, production cost and field productivity had negative relation to the total area of paddy field sold. Partially, fiel
Negative / Null Result ReportOpen accessVeterinary medicine
Mengen Zhang, Rui Han, Anguo Zhang et al. · 2026 · Animals
This study explored the differences in slaughter performance, blood biochemical indices, and ruminal and colonic microbiota between 6-month-old male and female Small-tailed Han sheep, a typical meat-wool dual-purpose breed in China. Twenty weaned lambs (10 males and 10 females) with uniform body condition were reared under unified feeding management until 6 months of age, followed by slaughter sampling and microbial sequencing detection. Results showed that male lambs had significantly higher pre-slaughter live weight, carcass weight and serum ALP content than females ( p p p p = 0.001). Sex h
View details →DOI: 10.3390/ani16091332 Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Carolina Biliotti, Nicolò Fraccaroli, Michelangelo Puliga et al. · 2025 · Journal of Medical Internet Research
BackgroundAs the spread of the SARS-CoV-2 virus coincided with lockdown measures, it is challenging to distinguish public reactions to lockdowns from responses to COVID-19 itself. Beyond the direct impact on health, lockdowns may have worsened public sentiment toward politics and the economy or even heightened dissatisfaction with health care, imposing a significant cost on both the public and policy makers. ObjectiveThis study aims to analyze the causal effect of COVID-19 lockdown policies on various dimensions of sentiment and uncertainty, using the Italian lockdown of February 2020 as a qua
View details →DOI: 10.2196/64667 Negative / Null Result ReportOpen accessFinance
Mevan Said Ali, Mufeed D. Y. Almula-Dhanoon · 2021 · Tikrit Journal of Administrative and Economic Sciences
The research aims to measure the impact of different variables on the youth unemployment rate in the Arab countries. Youth unemployment rates in the Arab countries are the highest in the world, and this requires serious consideration to address it, as it considered a major factor in political instability. The research used the multiple linear regression method and panel data for the period 1990-2019 for ten Arab countries for which the data required for the research were available: Iraq, Algeria, Libya, Sudan, Tunisia, Syria, Jordan, Morocco, Lebanon and Egypt. The analysis included measuring
View details →DOI: 10.25130/tjaes.17.54.3.26 Negative / Null Result ReportOpen accessMedicine
Mohsen Dalband, Mona Isapour, Pantea Nazeman · 2016 · Regeneration, Reconstruction & Restoration
Introduction: Antibiotics are routinely administered in clinical setting for prevention of infections in surgeries and as a routine supplement to the culture medium. The nobility of the present study was to evaluate the effect of two commonly used antibiotics, clindamycin and cefazolin, in dental treatments, on osteogenic capability of periodontal ligament stem cells (PDLSCs). Materials and Methods: PDLSCs were isolated from periodontal ligament (PDL) of the root section out of four healthy extracted teeth. The cells were incubated in the following medium for 28 days: (1) Osteogenic medium (OM
View details →DOI: 10.22037/rrr.v1i3.13353 Negative / Null Result ReportOpen accessBusiness
RITA SUIRLAN, SUIRLAN · 2024 · Sriwijaya International Journal of Dynamic Economics and Business
This research examines the efforts that must be made by the government in realizing strong food security through indicators of the sustainable food sector on the island of Sumatra for 2018-2022. Food sector indicators include poor population , food inflation, per capita rice consumption, insufficient food consumption, and food insecurity. While indicators to strengthen food security by looking at the food security index. The research findings that the variable food inflation (IBM) has a positive and significant effect on the food security index (IKP), while the variables of the poor (PM), rice
View details →DOI: 10.29259/sijdeb.v8i1.107-128 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Jiawei Chen, Hongsheng Deng, Jiaxi He et al. · 2022 · Frontiers in Oncology
IntroductionThe interval between neoadjuvant immunochemotherapy and surgery in patients with non-small cell lung cancer (NSCLC) has not been well characterized. This study investigated the association between the time-to-surgery (TTS) interval and surgical–pathological outcomes.MethodClinical data of patients who received neoadjuvant immun-ochemotherapy followed by surgery for NSCLC between January 2019 and September 2021 were collected. The patients were divided into three groups based on TTS interval: the early-surgery group (ESG), the standard-surgery group (SSG), and the delayed-surgery gr
View details →DOI: 10.3389/fonc.2022.909726 Negative / Null Result ReportOpen accessMedicine
Amin Ebneshahidi, Mojtaba Akbari, Masood Mohseni · 2013 · Advanced Biomedical Research
Introduction: Haloperidol has an established role in nausea and vomiting prophylaxis and possible effects on multiple aspects of postoperative recovery including pain and sedation. The purpose of this study was to evaluate the effects of low-dose intraoperative intravenous haloperidol on quality of recovery (QoR) and pain control after general anesthesia and surgery. Methods: Ninety eight American Society of Anesthesiologists (ASA) physical status I-II patients undergoing elective general, gynecologic or orthopedic surgery under general anesthesia were enrolled. Participants were randomly allo
View details →DOI: 10.4103/2277-9175.122501 Negative / Null Result ReportOpen accessAgriculture
Dija BHANDARI, Stella ARLOVIĆ, Marija GALIĆ et al. · 2024 · Journal of Central European Agriculture
The cultivation of energy crops and the use of biomass ash are part of a sustainable energy economy and have a major impact on the environment. Biomass ash can be used as a soil conditioner due to its chemical composition with essential micro- and macronutrients and has a proven positive effect on the physicochemical properties of soils. With the increasing interest and use of bioenergy species, the production of biomass ash is also increasing and is expected to increase further in the future. Therefore, the correct use of this product is important. Ensuring its use to enrich soils will streng
View details →DOI: 10.5513/jcea01/25.3.4339 Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Camila Viecceli, Camila Viecceli, Ana Carolina Viana Mattos et al. · 2022 · Frontiers in Endocrinology
ObjectiveThe first-line treatment for Cushing’s disease is transsphenoidal surgery, after which the rates of remission are 60 to 80%, with long-term recurrence of 20 to 30%, even in those with real initial remission. Drug therapies are indicated for patients without initial remission or with surgical contraindications or recurrence, and ketoconazole is one of the main available therapies. The objective of this study was to evaluate the safety profile of and the treatment response to ketoconazole in Cushing’s disease patients followed up at the endocrinology outpatient clinic of a Brazilian uni
View details →DOI: 10.3389/fendo.2022.1017331 