Negative / Null Result Report
Turner TJ, Brun P, Gruber R et al. · 2024 · Preprint
Tolebrutinib is a covalent BTK inhibitor designed and selected for potency and CNS exposure to optimize impact on BTK-dependent signaling in CNS-resident cells. We applied a translational approach to evaluate three BTK inhibitors in Phase…
View details →DOI: 10.1101/2024.03.25.586667 Negative / Null Result ReportOpen accessMedicine
Al-Khalaifah H, Al-Nasser A, Al-Surrayai T · 2025 · Life (Basel, Switzerland)
There is growing interest in adding marine algae to poultry feed rations. The aim of the present study is to examine the effect of various inclusions of Sargassum sp., Gracilaria sp., and Spirulina sp. on productive performance, serum…
View details →DOI: 10.3390/life15040670 Negative / Null Result ReportOpen accessMedicine
Zamora Veliz HY, Paredes Cabanillas RY, Gomez Trejo JE et al. · 2025 · Cureus
Introduction Intestinal anastomotic leakage is a serious postoperative complication associated with high morbidity and mortality. Although acute-phase reactants such as procalcitonin (PCT) and CRP have been proposed as early biomarkers,…
View details →DOI: 10.7759/cureus.88190 Negative / Null Result ReportOpen accessMedicine
Halačová M, Mieresová M, Kubele J et al. · 2026 · Pharmacological reports : PR
BACKGROUND: Beta-lactams are the cornerstone of therapy for the treatment of the most serious infections in the intensive care unit (ICU) setting. However, individualization of dosing remains challenging because pharmacokinetics are highly…
View details →DOI: 10.1007/s43440-026-00836-8 Negative / Null Result ReportOpen accessMedicine
Dumont JR, Sheppard PAS, Fodor C et al. · 2025 · Genes, brain, and behavior
Alzheimer's disease is a debilitating neurodegenerative condition characterized by amyloid beta plaques and tau neurofibrillary tangles, which leads to progressive cognitive decline. Several new mouse models of fast amyloid deposition have…
View details →DOI: 10.1111/gbb.70024 Negative / Null Result ReportMedicine
Langevin P, Frémont P, Fait P et al. · 2024 · Disability and rehabilitation
Purpose The objective of this study was to compare the effects of an in-clinic cervicovestibular rehabilitation program (education, home exercises, manual techniques, sub-symptom threshold aerobic exercise [STAE] program) to a similar…
View details →DOI: 10.1080/09638288.2023.2236016 Negative / Null Result ReportMedicine
Schleifenbaum L, Stern J, Driebe JC et al. · 2024 · Hormones and behavior
Previous research on the endogenous effects of ovarian hormones on motivational states in women has focused on sexual motivation. The Motivational Priority Shifts Hypothesis has a broader scope. It predicts a shift from somatic to…
View details →DOI: 10.1016/j.yhbeh.2024.105542 Negative / Null Result ReportMedicine
Fumagalli D, Sonik R, De Vitis LA et al. · 2024 · Gynecologic oncology
Background Advanced epithelial ovarian cancer (OC) patients often present with malnutrition; however, the ideal nutritional evaluation tool is unclear. We aimed to evaluate the role of preoperative albumin, Prognostic Nutritional Index…
View details →DOI: 10.1016/j.ygyno.2024.06.021 Negative / Null Result ReportOpen accessMedicine
Figueiredo RR, de Azevedo AA, Figueiredo GMR et al. · 2026 · Brazilian journal of otorhinolaryngology
Objectives COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our…
View details →DOI: 10.1016/j.bjorl.2026.101857 Negative / Null Result ReportMedicine
Mann S, Juhl CB, Paarup HM et al. · 2024 · Work (Reading, Mass.)
Background Playing the violin often requires a rotated and lateral flexed neck, leading to potential neck and shoulder problems. An ergonomic chinrest (EC) with or without a shoulder rest (SR or WSR) may enhance neutral neck positioning,…
View details →DOI: 10.3233/wor-220518 Negative / Null Result ReportMedicine
Wiener RC, Abuhalimeh B, Cochran J · 2025 · Community dentistry and oral epidemiology
Objective The objective of this research was to determine if the ratio of family income to poverty index is a modifier in the relationship of sugar-sweetened beverages (SSB) and dental caries in U.S. children. Methods A cross-sectional…
View details →DOI: 10.1111/cdoe.70000 Negative / Null Result ReportOpen accessMedicine
Schwarzer NH, Behringer N, Dees P et al. · 2026 · BMC psychology
Background The Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) assesses individual differences in epistemic stances. Although widely used, its German translation has not yet undergone an independent psychometric evaluation.…
View details →DOI: 10.1186/s40359-026-04810-0 Negative / Null Result ReportOpen accessMedicine
Taniajura N, Rincon C, Kennedy S et al. · 2026 · Addictive behaviors reports
Research has demonstrated that exposure to alcohol-related cues (e.g., sight or smell of a preferred beverage) elicits heightened self-reported craving and psychophysiological responses, including changes in heart rate (HR) and heart rate…
View details →DOI: 10.1016/j.abrep.2026.100687 Negative / Null Result ReportOpen accessMedicine
Barrera G, Albiach-Serrano A, Guillén-Salazar F · 2024 · Animal cognition
Studies have shown that horses are sensitive to human attentional cues. Also, there is some evidence that they might be able to infer the knowledge state of a human and communicate intentionally with us. However, this ability is not fully…
View details →DOI: 10.1007/s10071-024-01909-y Negative / Null Result ReportMedicine
Bansal M, Mehta A, Morris DL et al. · 2025 · Proceedings (Baylor University. Medical Center)
Background This study sought to assess the outcomes of pulmonary embolism (PE) admissions at teaching and nonteaching hospitals in the month of July, when new trainees begin their training in the United States. Methods During 2016-2021,…
View details →DOI: 10.1080/08998280.2025.2520125 Negative / Null Result ReportMedicine
Ruiz VH, Gill CM, Nicolau DP · 2024 · The Journal of antimicrobial chemotherapy
Objectives To evaluate the efficacy of human-simulated regimens (HSRs) of ceftazidime, ceftazidime/avibactam, imipenem, imipenem/relebactam, meropenem and meropenem/vaborbactam in a murine thigh infection model against serine…
View details →DOI: 10.1093/jac/dkad412 Negative / Null Result ReportOpen accessMedicine
Schaefer M, Liedtke C, Enge S · 2025 · Scientific reports
Recent reports challenge the view that placebos need to be given in deception. Numerous studies report remarkable effects when giving placebos honestly in an open way. However, the mechanisms of open-label placebos still remain to be…
View details →DOI: 10.1038/s41598-025-27622-5 Negative / Null Result ReportOpen accessMedicine
Tortolani AF, Kunigk NG, Sobinov AR et al. · 2025 · Journal of neural engineering
Objective . As brain-computer interface (BCI) research advances, many new applications are being developed. Tasks can be performed in different virtual environments, and whether a BCI user can switch environments seamlessly will influence…
View details →DOI: 10.1088/1741-2552/adb078 Negative / Null Result ReportOpen accessMedicine
Rogers ER, Sankarasubramanian V, Kyi WHT et al. · 2025 · Journal of pain research
Purpose The analgesic mechanisms and neurophysiological effects of spinal cord stimulation (SCS) and dorsal root ganglion stimulation (DRGS) are poorly understood. In this pilot repeated-measures study, we used quantitative sensory testing…
View details →DOI: 10.2147/jpr.s519187 Negative / Null Result ReportOpen accessMedicine
Stapley V, Anderson RS, Saunders K et al. · 2025 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Introduction Previous research suggests that the electroretinogram (ERG) is reduced and delayed in non-pathological myopia. However, the invasive nature of the electrode and cumbersome equipment required has prevented the widescale uptake…
View details →DOI: 10.1111/opo.13460 Negative / Null Result ReportOpen accessMedicine
Fowler PV, Keall H, Kennedy D et al. · 2025 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
ObjectivesTo investigate cleft laterality dental arch relationship outcomes of children with non-syndromic complete unilateral cleft lip and palate (UCLP) in New Zealand.DesignA retrospective nationwide study.SettingsVirtual 3D orthodontic…
View details →DOI: 10.1177/10556656241234599 Negative / Null Result ReportOpen accessMedicine
Rachuene PA, Dey R, Kauta NJ et al. · 2024 · SICOT-J
Background Pre-operative planning for reverse shoulder arthroplasty (RSA) poses challenges, particularly when dealing with glenoid bone loss. This modified Delphi study aimed to assess expert consensus on RSA planning processes and…
View details →DOI: 10.1051/sicotj/2024021 Negative / Null Result ReportOpen accessMedicine
Iwagami S, Miyai H, Nishihata M · 2026 · Research and reports in urology
Purpose Transperineal prostate biopsy is essential for diagnosing prostate cancer; however, infection remains a clinically significant issue. We evaluated the safety and outcome of a single, prophylactic oral dose of cefaclor 500mg during…
View details →DOI: 10.2147/rru.s586606 Negative / Null Result ReportOpen accessMedicine
Ashaibi NA, Mason AG, Hector MP et al. · 2025 · Clinical and experimental dental research
Objectives Dental pain of odontogenic origin can be difficult to accurately locate to a specific tooth. This study aimed to determine how effectively volunteers could locate electrical stimuli applied to teeth in both the anterior and…
View details →DOI: 10.1002/cre2.70012 Negative / Null Result Report
Glanzer BM, Ladki MS, Chea M et al. · 2023 · Preprint
This study tests the utilization of Bluetooth noise-canceling headphones in improving the quality of eye exams in patients with hearing loss. University of Texas Medical Branch patients above 55 years of age were screened for hearing loss…
View details →DOI: 10.20944/preprints202310.1157.v1 Negative / Null Result ReportOpen accessMedicine
Schlötelburg W, Hartrampf PE, Kosmala A et al. · 2024 · Endocrine
Purpose We aimed to evaluate the prognostic potential of baseline [ 18 F]FDG PET/CT for overall survival (OS) in patients with adrenocortical carcinoma (ACC). Methods We performed a retrospective analysis of 67 treatment-naïve ACC patients…
View details →DOI: 10.1007/s12020-024-03695-6 Negative / Null Result Report
von Gönner J, Gröning J, Grescho V et al. · 2023 · Preprint
Agricultural pesticides, nutrients, and habitat degradation are major causes of insect declines in lowland streams. To effectively conserve and restore stream habitats, standardized stream monitoring data and societal support for…
View details →DOI: 10.1101/2023.10.27.564349 Negative / Null Result ReportMedicine
Byington CG, Goodman AM, Allendorfer JB et al. · 2024 · Epilepsia
Objective The uncinate fasciculus (UF) has been implicated previously in contributing to the pathophysiology of functional (nonepileptic) seizures (FS). FS are frequently preceded by adverse life events (ALEs) and present with comorbid…
View details →DOI: 10.1111/epi.17896 Negative / Null Result ReportOpen accessMedicine
Mohammadzadeh M, Abdi F, Hadi S et al. · 2026 · BMC nutrition
Background A high-quality diet is an important strategy for preventing chronic diseases, including cancer. The Nutrient Rich Food Score (NRFS) is a very useful index that can compare the value of key micronutrients and macronutrients per…
View details →DOI: 10.1186/s40795-026-01243-1 Negative / Null Result ReportOpen accessMedicine
Soufi R, Salamzadeh J, Alavi Darazam I et al. · 2025 · Iranian journal of pharmaceutical research : IJPR
Background Vancomycin is commonly used in intensive care units (ICUs), but its optimal dosage in patients with acute kidney injury (AKI) remains uncertain. This study aimed to evaluate vancomycin's pharmacokinetic and pharmacodynamic…
View details →DOI: 10.5812/ijpr-159089 