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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21350 results · page 578 of 712

Negative / Null Result ReportOpen accessMedicine

Detectability of Automated Tumor-feeder Detection Software Using Angio-computed Tomography in Transarterial Chemoembolization for Hepatocellular Carcinoma.

Ueda M, Mitani H, Nakaki Y et al. · 2025 · Interventional radiology (Higashimatsuyama-shi (Japan)

Purpose: To evaluate the performance of automated tumor-feeder detection software in transarterial chemoembolization for hepatocellular carcinoma using angio-computed tomography. Material and Methods: This was a retrospective study of 107…

View details →DOI: 10.22575/interventionalradiology.2025-0007
Negative / Null Result ReportMedicine

The severity and outcomes in acute pancreatitis do not differ between the elderly and non-elderly patients: Experience in a clinical tertiary center.

Ruiz-Rebollo ML, Muñoz-Moreno MF · 2025 · Medicina clinica

Background Acute pancreatitis can affect elderly people. Conflicting results have been published regarding the role of age in the course of this life-threatening disease. Aim To assess the clinical outcomes of acute pancreatitis in…

View details →DOI: 10.1016/j.medcli.2025.107112
Negative / Null Result ReportMedicine

Optical Genome Mapping in Myelodysplastic Syndromes: Clinical Value and Limitations Derived From a Cohort of 236 Patients.

Wei Q, Wang SA, Garcia-Manero G et al. · 2025 · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Identification of cytogenetic abnormalities is critical for the classification and risk stratification of myelodysplastic syndromes (MDS). Optical genome mapping (OGM) is an emerging cytogenomic platform that enables high-resolution…

View details →DOI: 10.1016/j.modpat.2025.100862
Negative / Null Result ReportOpen accessMedicine

Comparative Diagnostic Accuracy of MRI and Ultrasound in Meniscal Tear Detection: Evaluating Reliability and Limitations Against Arthroscopic Outcomes.

Noorelahi Y · 2025 · Radiology research and practice

Objective Accurate meniscal tear diagnosis is essential for proper knee injury management. While MRI is the gold standard, ultrasound (US) offers a cost-effective alternative. However, its accuracy compared to arthroscopy remains…

View details →DOI: 10.1155/rrp/6270476
Negative / Null Result ReportMedicine

West Nile Virus Antibody Prevalence in Horses During the 2023 Outbreak in Tunisia, North Africa.

Dachraoui K, Ben Osman R, Ben Slama S et al. · 2025 · Vector borne and zoonotic diseases (Larchmont, N.Y.)

A total of 20 horses belonging to the Pasteur Institute of Tunis used for the production of therapeutic serum antiscorpion venom were tested for the presence of antibodies anti-West Nile virus (WNV) during the 2023 outbreak of West Nile…

View details →DOI: 10.1177/15303667251359822
Negative / Null Result ReportMedicine

Performance of creatinine and cystatin C-based equations to estimate glomerular filtration rate in African children with sickle cell anemia.

Nkoy AB, Mumaka FM, Matoka TT et al. · 2026 · Pediatric nephrology (Berlin, Germany)

Background Serum creatinine (SCr), the most used biomarker to evaluate glomerular filtration rate (GFR), might be inaccurate in children with sickle cell anemia (SCA). In this context, cystatin C (SCys) could be of interest. This study…

View details →DOI: 10.1007/s00467-025-06986-w
Negative / Null Result ReportOpen accessMedicine

Genome-resolved metagenomics reveals unexpected diversity and host range of Candidatus Lariskella (Rickettsiales: Midichloriaceae).

Hagenbeek A, Masukagami Y, Palanichamy P et al. · 2026 · BMC genomics

The intracellular endosymbiont Candidatus Lariskella (Alphaproteobacteria, Candidatus Midichloriaceae) has been found across a wide diversity of terrestrial arthropods, including ticks, true bugs, beetles, fleas, wasps and moths. Despite…

View details →DOI: 10.1186/s12864-026-12881-x
Negative / Null Result ReportMedicine

Nationwide Survey of Laboratory Practices for Factor VIII Inhibitor Detection in China.

Wang Y, Kong X, Wei H et al. · 2025 · Haemophilia : the official journal of the World Federation of Hemophilia

Introduction The Bethesda assay (BA) and the Nijmegen-Bethesda assay (NBA) are commonly used to measure inhibitors in patients with haemophilia A (HA). The laboratory results of inhibitor assays have been demonstrated to be highly…

View details →DOI: 10.1111/hae.70084
Failed Experiment Report

† Cryptovaranoides is not a squamate

Caldwell MW, Brownstein CD, Meyer DL et al. · 2025 · Preprint

Accurate reconstruction of the timescale of organismal evolution requires placement of extinct representatives among living branches. In this way, the fossil record has the capacity to revise hypotheses of organismal evolution by producing…

View details →DOI: 10.1101/2025.04.18.649532
Negative / Null Result ReportMedicine

Polymerase chain reaction fails to detect mixed malaria infections in siblings from Ethiopia.

Hall AD, Whitehurst DA, Mortensen JE et al. · 2025 · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

Malaria remains a significant public health concern in sub-Saharan Africa, particularly in Ethiopia where Plasmodium falciparum and Plasmodium vivax are co-endemic. Most cases in the United States are acquired abroad and imported.…

View details →DOI: 10.1016/j.jiac.2025.102777
Negative / Null Result ReportMedicine

Real-time PCR versus culture of bronchoalveolar lavage fluid for detecting Bordetella bronchiseptica in dogs with persistent lower respiratory signs: a retrospective study of 23 cases.

Atencia S, Mateu N, Rodríguez-Cobos A et al. · 2025 · Veterinary research communications

Bordetella bronchiseptica (Bb) is a frequent pathogen in dogs and a component of the Canine Infectious Respiratory Disease Complex (CIRDC). However, it can also be detected in the lower respiratory tract of healthy animals, complicating…

View details →DOI: 10.1007/s11259-025-10826-5
Negative / Null Result Report

The Effect of Resistance Training Volume on Individual-Level Skeletal Muscle Adaptations: A Novel Replicated Within-Participant Unilateral Trial

Robinson ZP, Steele J, Helms ER et al. · 2025 · Preprint

ABSTRACT Purpose There is growing emphasis on investigating heterogeneity in resistance training (RT) outcomes, likely motivated by observations of substantial gross variability in training effects. However, gross variability does not…

View details →DOI: 10.1101/2025.07.24.666533
Negative / Null Result ReportMedicine

Bactericera maculipennis (Hemiptera: Triozidae) is a vector of "Candidatus Liberibacter solanacearum" to species within the Convolvulaceae (Solanales).

Cooper WR, Ohler B, Wenninger EJ et al. · 2025 · Environmental entomology

Bactericera maculipennis (Crawford) and Bactericera cockerelli (Šulc) (Hemiptera: Triozidae) share hosts within the Solanaceae and Convolvulaceae (Solanales), and both are associated with "Candidatus Liberibacter solanacearum" (Lso). Lso,…

View details →DOI: 10.1093/ee/nvaf088
Negative / Null Result ReportMedicine

Efficacy and safety of chemotherapy combined with iodine-125 seed brachytherapy for intermediate and advanced oncogenic driver gene-negative non-small cell lung cancer.

Xia MH, Liu KC, Zhao W et al. · 2025 · Brachytherapy

Purpose To compare the effectiveness and safety of CT-guided iodine-125 seed brachytherapy in conjunction with chemotherapy against chemotherapy alone for the management of intermediate and advanced non-small cell lung cancer (NSCLC)…

View details →DOI: 10.1016/j.brachy.2024.09.005
Negative / Null Result ReportOpen accessMedicine

Phase 1 LITESPARK-001 study of belzutifan in participants with advanced solid tumors: Results of the glioblastoma expansion cohort.

Strowd RE, de la Fuente M, Bauer TM et al. · 2026 · Neuro-oncology advances

Recurrent isocitrate dehydrogenase (IDH) wild-type glioblastoma has no established standard-of-care treatment. Preclinical models have demonstrated that hypoxia-inducible factor-2 alpha (HIF-2α) contributes to stabilizing the hypoxic…

View details →DOI: 10.1093/noajnl/vdaf242
Failed Experiment ReportMedicine

Identification of novel variants in BRF1 gene from patient with developmental delay, hearing abnormality, and nervous system anomalies.

Yin H, Yu Y, Shen Y · 2024 · International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience

Cerebellofaciodental syndrome characterized with dysmorphic features, intellectual disability, and brain anomalies. Now its clinical spectrum expanded more manifestations including bilateral sensorineural hearing impairment and inner ear…

View details →DOI: 10.1002/jdn.10365
Negative / Null Result ReportOpen accessMedicine

Is Fel d1 Based Component Resolved Diagnosis Associated With Airway Inflammation in Cat Sensitized Children?

Kaya G, Yüksel H, Taneli F et al. · 2026 · Clinical and translational science

In cat sensitized children, decision to eliminate exposure to cats depends on the clinical outcome. In this study, we aimed to examine the relationship between molecular cat allergen sensitization and exhaled breath condensate (EBC) IL-4,…

View details →DOI: 10.1111/cts.70521