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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 575 of 676

Negative / Null Result Report

Parietal theta burst TMS does not modulate bistable perception

Schauer G, Grassi PR, Gharabaghi A et al. · 2023 · Preprint

The role of the parietal cortex in perceptual awareness and in resolving perceptual ambiguity is unsettled. Early influential TMS studies have revealed differences in conscious perception following parietal stimulation, fuelling the notion…

View details →DOI: 10.31234/osf.io/nrvza
Negative / Null Result ReportOpen accessMedicine

No evidence that sociosexual orientation moderates effects of conception probability on women's preferences for male facial masculinity.

Lee AJ, Jones BC, Zietsch BP et al. · 2023 · Scientific reports

Although many researchers have proposed that women will show stronger preferences for male facial masculinity when conception probability is high, empirical tests of this hypothesis have produced mixed results. One possible explanation for…

View details →DOI: 10.1038/s41598-023-37404-6
Negative / Null Result ReportOpen accessMedicine

A Five-Year Retrospective Study: Relationship Between Cervical Spine Whiplash Injuries and Demyelinating Diseases in the Pediatric Population.

Kardouh MS, Van Wagoner C, Coleman J et al. · 2026 · Cureus

Objectives Whiplash injuries are among the most common cervical spine injuries in the pediatric population. Limited literature demonstrates a potential link between cervical spine trauma and demyelinating disease, such as multiple…

View details →DOI: 10.7759/cureus.104866
Negative / Null Result ReportOpen accessMedicine

Vitamin D Supplementation in Children with Asthma: An Umbrella Review.

Liu J, Long Y, Yang Z · 2026 · Nutrients

Background Growing evidence suggests that vitamin D plays a role in the pathophysiology of childhood asthma. However, its effectiveness in reducing asthma exacerbations and improving asthma-related outcomes remains controversial. Methods…

View details →DOI: 10.3390/nu18101560
Negative / Null Result ReportMedicine

Gastrointestinal tract exposure to particles and DNA damage in animals: A review of studies before, during and after the peak of nanotoxicology.

Møller P, Roursgaard M · 2024 · Mutation research. Reviews in mutation research

Humans ingest particles and fibers on daily basis. Non-digestible carbohydrates are beneficial to health and food additives are considered safe. However, titanium dioxide (E171) has been banned in the European Union because the European…

View details →DOI: 10.1016/j.mrrev.2024.108491
Negative / Null Result ReportOpen accessMedicine

Pro-inflammatory dietary patterns and their association with cardiovascular disease and pancreatic cancer in a hospital population: a cross-sectional study.

Jin Q, Liu Y, Tong Q et al. · 2025 · Frontiers in nutrition

Objective To examine whether a concise, clinic-feasible Patient Inflammatory Diet Score (PIDS) relates to prevalent pancreatic cancer and cardiovascular disease (CVD) in a hospital population, and to explore associations with systemic…

View details →DOI: 10.3389/fnut.2025.1666682
Negative / Null Result ReportMedicine

Learning to draw parametric faces.

Davidenko N, Day J · 2025 · Memory & cognition

Humans' ability to draw faces accurately from memory is extremely rare. One source of difficulty is the drawing process itself, which requires converting a complex, three-dimensional mental representation to a two-dimensional drawing. To…

View details →DOI: 10.3758/s13421-023-01498-0
Negative / Null Result ReportMedicine

Extreme ambient heat and outcomes of assisted reproduction in the continental United States, 1996 to 2018.

Gaskins AJ, Newman AJ, Kawwass JF et al. · 2026 · Environmental research

Background While extreme ambient heat has been associated with several adverse pregnancy and birth outcomes little is known regarding the link between extreme ambient temperatures and human fertility. Objective To evaluate the associations…

View details →DOI: 10.1016/j.envres.2026.123783
Negative / Null Result ReportOpen accessMedicine

No evidence that visual impulses enhance the readout of retrieved long-term memory contents from EEG activity.

van Bree S, Mackenzie AS, Wimber M · 2024 · Imaging neuroscience (Cambridge, Mass.)

The application of multivariate pattern analysis (MVPA) to electroencephalography (EEG) data allows neuroscientists to track neural representations at temporally fine-grained scales. This approach has been leveraged to study the locus and…

View details →DOI: 10.1162/imag_a_00330
Negative / Null Result ReportOpen accessMedicine

Sodium Reduction Program Incorporating Genetic Profile and an AI-Based App: A Randomized Clinical Trial.

Sato K, Inoue K, Yamaguchi T et al. · 2025 · JAMA network open

Importance Excess salt intake is a major modifiable risk factor for hypertension and cardiovascular disease. Personalized interventions using genetic information and digital tools, such as smartphone applications, may enhance sodium…

View details →DOI: 10.1001/jamanetworkopen.2025.37540
Negative / Null Result ReportOpen accessMedicine

No Genetic Causal Relationship Between HIV Infection and Insulin Resistance, Diabetes: A Bidirectional Mendelian Randomization Analysis.

Liu P, Zeng Q · 2025 · Journal of multidisciplinary healthcare

Background The causal relationship between HIV infection and insulin resistance, as well as diabetes mellitus, remains uncertain. This study explores these associations using genome-wide association study data and Mendelian randomization…

View details →DOI: 10.2147/jmdh.s546669
Negative / Null Result ReportOpen accessMedicine

New Vistas for the Relationship between Empathy and Political Ideology.

Zebarjadi N, Kluge A, Adler E et al. · 2024 · eNeuro

The study of ideological asymmetries in empathy has consistently yielded inconclusive findings. Yet, until recently these inconsistencies relied exclusively on self-reports, which are known to be prone to biases and inaccuracies when…

View details →DOI: 10.1523/eneuro.0086-24.2024
Negative / Null Result ReportOpen accessMedicine

In the eastern Mediterranean, the rat lungworm Angiostrongylus cantonensis is absent or extremely rare according to recent surveys.

Anettová L, Šipková A, Cibulka P et al. · 2025 · Parasitology research

This study summarizes the findings of a comprehensive field investigation into the presence of Angiostrongylus cantonensis, a zoonotic nematode responsible for meningitis, in selected regions of the eastern Mediterranean. Samples were…

View details →DOI: 10.1007/s00436-025-08580-3
Negative / Null Result ReportMedicine

College Student Video Gaming: Risk or Resilience for Mental Health?

Vengurlekar IN, Thudi KR · 2025 · Psychological reports

Video gaming has become a popular method of entertainment for college students. Previous work indicates mixed results regarding the link between video gaming and mental health outcomes. However, little research has addressed how different…

View details →DOI: 10.1177/00332941231196551
Negative / Null Result ReportMedicine

Post-occlusive reactive hyperemia in habituated caffeine users: Effects of abstaining versus consuming typical doses.

Chatlaong MA, Stanford DM, Miller WM et al. · 2024 · Clinical hemorheology and microcirculation

Background Post-occlusive reactive hyperemia (PORH) typically requires caffeine abstinence. For habitual users, it is unknown if abstinence affects PORH. Objective Compare PORH after habitual users consume or abstain from caffeine. Methods…

View details →DOI: 10.3233/ch-232036
Negative / Null Result Report

This is a question? Prosody and the N400 effect

Kaplan-Kahn EA, Russell M, Kellen D et al. · 2023 · Preprint

In spoken language, the prosodic contours of a speaker’s voice, including the volume, duration, and intonation of each syllable, influence the moment-to-moment processing of the utterance’s meaning. A robust body of literature supports the…

View details →DOI: 10.31234/osf.io/hyjzn
Negative / Null Result ReportMedicine

Replicability of Highly Cited Comparative Studies in Orthopedic Journals.

Ashy C, Few WE, Rivas GA et al. · 2026 · HCA healthcare journal of medicine

Introduction Concerns are rising regarding the quality, validity, and reliability of clinical research findings in medical literature. This investigation sought to identify the most cited orthopedic clinical studies and assess the…

View details →DOI: 10.36518/2689-0216.2188
Negative / Null Result ReportOpen accessMedicine

Intake of the Total, Classes, and Subclasses of (Poly)phenols and Breast Cancer Risk: A Prospective Analysis of the EPIC Study.

López-Padilla MF, Seoane-Miraz D, Guiñón-Fort D et al. · 2026 · Antioxidants (Basel, Switzerland)

Polyphenols represent the largest and most diverse class of dietary antioxidants. Epidemiological evidence linking specific (poly)phenol classes, such as flavonoids and lignans, to breast cancer (BC) risk remains limited and largely…

View details →DOI: 10.3390/antiox15030342
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by inducing status competition?

Lazarevic LB, Wagge JR, Balci BB et al. · 2023 · Preprint

The present study presents results of a collaborative registered replication of Griskevicius et al.’s (2010) findings from Experiment 1 conducted by 24 student groups from six countries (N = 3,774) investigating if pro-environmental…

View details →DOI: 10.31234/osf.io/sfmz8
Negative / Null Result ReportOpen accessMedicine

Early and later susceptibility to effects of parenting: Exploring Frankenhuis and Panchanathan's (2011) evolutionary commitment hypothesis.

Zhang X, Machlin L, McLaughlin K et al. · 2025 · Developmental psychology

This study tests Frankenhuis and Panchanathan's (2011) evolutionary commitment hypothesis by examining individual differences in susceptibility to the effects of parenting during early and late childhood. Drawing from the Future of…

View details →DOI: 10.1037/dev0002023
Negative / Null Result ReportOpen accessMedicine

Musical groove listening does not enhance primary motor cortex activation.

O'Connell SR, Wilson GE, Berkowitz DH et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)

Groove is the pleasurable urge to move to the beat of music, a universally experienced human phenomenon. Because listeners are often inspired to move to music with groove, we asked whether high-groove music would promote greater motor…

View details →DOI: 10.1162/imag.a.1185
Negative / Null Result ReportMedicine

Impact of increasing workforce racial diversity on black-white disparities in cardiovascular disease mortality.

Colbeth HL, Riddell CA, Thomas M et al. · 2024 · Journal of epidemiology and community health

Background Structural racism's influence on workforce policies and practices presents possible upstream targets for assessing and reducing racial health disparities. This study is the first to examine workforce racial diversity in…

View details →DOI: 10.1136/jech-2024-222094
Negative / Null Result ReportOpen accessMedicine

Psychobehavioral profiles of eating risk: schema-emotion regulation patterns differ in central adiposity with genotype (FTO rs9939609) as external validator-a pilot study.

Obara-Gołębiowska M · 2026 · Eating and weight disorders : EWD

Purpose To identify person-centered psychological profiles of eating-related risk based on early maladaptive schemas (EMS), emotion regulation difficulties, and eating behaviors, and to examine their external validation using…

View details →DOI: 10.1007/s40519-026-01853-5